[go: up one dir, main page]

WO1992021654A3 - Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique - Google Patents

Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique Download PDF

Info

Publication number
WO1992021654A3
WO1992021654A3 PCT/US1992/001652 US9201652W WO9221654A3 WO 1992021654 A3 WO1992021654 A3 WO 1992021654A3 US 9201652 W US9201652 W US 9201652W WO 9221654 A3 WO9221654 A3 WO 9221654A3
Authority
WO
WIPO (PCT)
Prior art keywords
carboxamido
carbocyclic
aminotetralin derivatives
aminotetralin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1992/001652
Other languages
English (en)
Other versions
WO1992021654A2 (fr
Inventor
Chiu-Hong Lin
Montford E Piercey
Susanne R Haadsma-Svensson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to JP5500378A priority Critical patent/JPH06507906A/ja
Publication of WO1992021654A2 publication Critical patent/WO1992021654A2/fr
Publication of WO1992021654A3 publication Critical patent/WO1992021654A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)

Abstract

L'invention concerne des tetralines aux propriétés thérapeutiques et des sels d'addition acides pharmaceutiquement acceptables de ces tétralines de formule (I) où R est alkyle C1-C8 et n est 1 ou 2.
PCT/US1992/001652 1991-05-20 1992-03-11 Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique Ceased WO1992021654A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5500378A JPH06507906A (ja) 1991-05-20 1992-03-11 カルボキサミド−（３，２ｎ）−カルボサイクリック−２−アミノテトラリン誘導体

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70281391A 1991-05-20 1991-05-20
US702,813 1991-05-20

Publications (2)

Publication Number Publication Date
WO1992021654A2 WO1992021654A2 (fr) 1992-12-10
WO1992021654A3 true WO1992021654A3 (fr) 1993-01-07

Family

ID=24822712

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1992/001652 Ceased WO1992021654A2 (fr) 1991-05-20 1992-03-11 Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique

Country Status (6)

Country Link
EP (1) EP0586553A1 (fr)
JP (1) JPH06507906A (fr)
AU (1) AU2153592A (fr)
MX (1) MX9202291A (fr)
TW (1) TW200460B (fr)
WO (1) WO1992021654A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9612153D0 (en) * 1996-06-11 1996-08-14 Smithkline Beecham Plc Compounds
DE19834714A1 (de) * 1998-07-31 2000-02-03 Boehringer Ingelheim Pharma Neue 2,3,3a,4,9,9a-Hexahydro-8-hydroxy-1H-ben[f]indole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402601A1 (de) * 1983-02-01 1984-08-02 Sandoz-Patent-GmbH, 7850 Lörrach Neue pharmazeutisch aktive 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate, deren herstellung und verwendung
EP0272534A2 (fr) * 1986-12-22 1988-06-29 Bayer Ag Tétralines 2-amino 8-substituées
WO1991000856A2 (fr) * 1989-07-13 1991-01-24 The Upjohn Company DERIVES DE (1,2N) et (3,2N)-CARBOCYCLIQUE-2-AMINO TETRALINES

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402601A1 (de) * 1983-02-01 1984-08-02 Sandoz-Patent-GmbH, 7850 Lörrach Neue pharmazeutisch aktive 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate, deren herstellung und verwendung
EP0272534A2 (fr) * 1986-12-22 1988-06-29 Bayer Ag Tétralines 2-amino 8-substituées
WO1991000856A2 (fr) * 1989-07-13 1991-01-24 The Upjohn Company DERIVES DE (1,2N) et (3,2N)-CARBOCYCLIQUE-2-AMINO TETRALINES

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 106, no. 3, 19 January 1987, Columbus, Ohio, US; abstract no. 18332B, 'p-dimethoxy-substituted trans-octahydrobenzo(f)- and -(g)quinolines: synthesis and assessment of dopaminergic agonist effects' page 584 ; *
MOLECULAR PHARMACOLOGY vol. 35, no. 5, 1989, pages 643 - 651; 'characterization of dopamine receptor subtypes by comparative structure-activity relationships' *
PHARMAC. BIOCHEM. BEHAV. vol. 17, no. SUP1, 1982, pages 11 - 19; 'presynaptic Dopamine Receptor Agonists' *

Also Published As

Publication number Publication date
AU2153592A (en) 1993-01-08
WO1992021654A2 (fr) 1992-12-10
JPH06507906A (ja) 1994-09-08
MX9202291A (es) 1992-11-01
TW200460B (fr) 1993-02-21
EP0586553A1 (fr) 1994-03-16

Similar Documents

Publication Publication Date Title
AU5571190A (en) Retroviral protease inhibiting compounds
AU694417B2 (en) Cyclic ureas and analogues useful as retroviral protease inhibitiors
CA2064634A1 (fr) Derives de 9-desoxo-8a-aza-8a-homoerythromycine a modifies en positions 4"- et 8a
CA2165819A1 (fr) Derives de dc-89
CA2039056A1 (fr) Derives 3,5-di-butyle tertiaire-4-hydroxyphenylmethylene de triazolidinones, oxazolidinones et imidazolidinones a substitution en position 2, comme agents antiinflammatoires
CA2110693A1 (fr) Derive d'acide amine anticonvulsif
WO1992022523A3 (fr) Derives peptidiques utilises comme inhibiteurs de collagenase
AU1614492A (en) New peptide compound and a process for the preparation thereof
CA2129542A1 (fr) Preparation pharmaceutique a base de rhamnolipide
CA2204204A1 (fr) Derives de glucides
CA2066304A1 (fr) Composition pharmaceutique pour le traitement de maladies autoimmunes
DE69030665D1 (de) (1,2n) und (3,2n)-karbozyklische-2-amino-tetralinderivate
AU2496888A (en) Antibacterial 9-deoxo-9a-allyl and propargyl-9a-aza-9a-homoerythromycin a derivatives
WO1992021654A3 (fr) Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique
EP0201349A3 (fr) Dérivés de tétrazole
FI895139A0 (fi) Pyrrolidinderivat.
AU6231090A (en) N-azabicyclo(3.3.0)octane amides of aromatic acids
EP0784973A3 (fr) Dérivés de la quinoxaline pour le traitement du tintement d'oreille
AU2532692A (en) Method for treating hypertension
AU2014188A (en) Naphthothiazepine derivatives and preparation thereof
AP9400608A0 (en) "New nicotinic acid derivative".
TW275629B (fr)
AU3739595A (en) Antiherpes peptidomimetic compounds
IE901105L (en) Antibacterial 2-carbapenem derivatives
ES8703421A1 (es) Procedimiento para preparar derivados de pirrolidindiona.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU BB BG BR CA CS FI HU JP KP KR LK MG MN MW NO PL RO RU SD US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE BF BJ CF CG CH CI CM DE DK ES FR GA GB GN GR IT LU MC ML MR NL SE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AU BB BG BR CA CS FI HU JP KP KR LK MG MN MW NO PL RO RU SD US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE BF BJ CF CG CH CI CM DE DK ES FR GA GB GN GR IT LU MC ML MR NL SE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
EX32 Extension under rule 32 effected after completion of technical preparation for international publication

Ref country code: UA

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: PAT.BUL.31/92 UNDER INID (22) INTERNATIONAL FILING DATE REPLACE "920211" BY "920311"

LE32 Later election for international application filed prior to expiration of 19th month from priority date or according to rule 32.2 (b)

Ref country code: UA

WWE Wipo information: entry into national phase

Ref document number: 1992912819

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1992912819

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: CA

WWW Wipo information: withdrawn in national office

Ref document number: 1992912819

Country of ref document: EP