[go: up one dir, main page]

WO1988007367A3 - Melatonin-derivatives for psychogenic stress and acute anxiety, and immuno-stimulant drugs - Google Patents

Melatonin-derivatives for psychogenic stress and acute anxiety, and immuno-stimulant drugs Download PDF

Info

Publication number
WO1988007367A3
WO1988007367A3 PCT/EP1988/000270 EP8800270W WO8807367A3 WO 1988007367 A3 WO1988007367 A3 WO 1988007367A3 EP 8800270 W EP8800270 W EP 8800270W WO 8807367 A3 WO8807367 A3 WO 8807367A3
Authority
WO
WIPO (PCT)
Prior art keywords
melatonin
immuno
derivatives
acute anxiety
psychogenic stress
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1988/000270
Other languages
French (fr)
Other versions
WO1988007367A2 (en
Inventor
Walter Pierpaoli
Giorgio Maestroni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellena (Cell Engineering) AG
Original Assignee
Cellena (Cell Engineering) AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878707792A external-priority patent/GB8707792D0/en
Priority claimed from GB878707793A external-priority patent/GB8707793D0/en
Application filed by Cellena (Cell Engineering) AG filed Critical Cellena (Cell Engineering) AG
Publication of WO1988007367A2 publication Critical patent/WO1988007367A2/en
Publication of WO1988007367A3 publication Critical patent/WO1988007367A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

The invention relates to the use of melatonin or related active chemical compounds for the production of pharmaceutical compositions for the treatment of psychogenic stress or acute anxiety as well as for the enhancement of immune resistance in a host against viral and parasitical infections.
PCT/EP1988/000270 1987-04-01 1988-04-01 Melatonin-derivatives for psychogenic stress and acute anxiety, and immuno-stimulant drugs Ceased WO1988007367A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8707793 1987-04-01
GB8707792 1987-04-01
GB878707792A GB8707792D0 (en) 1987-04-01 1987-04-01 Compositions containing metatonin/homologues
GB878707793A GB8707793D0 (en) 1987-04-01 1987-04-01 Compositions containing melatonin/homologues

Publications (2)

Publication Number Publication Date
WO1988007367A2 WO1988007367A2 (en) 1988-10-06
WO1988007367A3 true WO1988007367A3 (en) 1989-01-26

Family

ID=26292085

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1988/000270 Ceased WO1988007367A2 (en) 1987-04-01 1988-04-01 Melatonin-derivatives for psychogenic stress and acute anxiety, and immuno-stimulant drugs

Country Status (3)

Country Link
EP (1) EP0311651A1 (en)
AU (1) AU1494788A (en)
WO (1) WO1988007367A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300630A3 (en) * 1987-07-03 1990-03-28 Schering Agrochemicals Limited Melatonin for regulating animal reproduction
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
GR900100024A (en) * 1989-01-17 1991-06-07 Amr Int Method of treating pre-menstual syndrome
EP0711553A1 (en) * 1994-08-09 1996-05-15 Mario Cagnoni Use of the Melatonin in the traetment of the articular symptoms of trheumatoid arthritis
JPWO2002060457A1 (en) * 2001-01-24 2004-05-27 天藤製薬株式会社 Anti-stress agent

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
J. Neutral Transm., suppl. 21, 1986, H.R. Lieberman: "Behavior, sleep and melatonin", pages 233-241 *
Medical Hypotheses, volume 7, no. 6, June 1981, J. Richardson et al.: "The mechanisms of stress and immunosuppression", pages 765-780 *
Peptides, volume 2, suppl. 1, 1981, ANKHO International Inc., (US), P.C. Datta: "Effects of melatonin on startle reflex in rat", pages 155-160 *
Pharmacology Biochemistry & Behavior, volume 15, 1981, ANKHO International Inc., (US), P. Golus et al.: "The effects of melatonin on open field behavior", pages 883-885 *
Pharmacology Biochemistry & Behavior, volume 24, no. 6, June 1986, ANKHO International Inc., (US), K. Neville et al.: "Anxiolytic-like action of melatonin on acquisition but not performance of DRL", pages 1497-1502 *

Also Published As

Publication number Publication date
AU1494788A (en) 1988-11-02
WO1988007367A2 (en) 1988-10-06
EP0311651A1 (en) 1989-04-19

Similar Documents

Publication Publication Date Title
HUP0002224A1 (en) Benzimidazole derivatives of antivirus activity
MY138860A (en) Hiv protease inhibitors.
PT88930A (en) METHOD FOR THE PREPARATION OF NEW ANALYSES OF NUCLEOSIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
MXPA04012965A (en) Viral inhibitors.
BR0309875A (en) methods and compositions for treating peripheral nervous system disorders and novel compounds useful therefor
NO20052739L (en) CCR5 antagonists as drugs
SE0104340D0 (en) New compounds
NO324227B1 (en) Cyclopropyl-fused pyrrolidine-based compounds, pharmaceutical compositions and combinations containing them as well as the use thereof for the manufacture of medicaments for the treatment of diseases
MD1224B2 (en) Application of nucleoside analogues with 1,3-oxathiolan for treatment of hepatitis B
EA200700362A1 (en) CONJUGAT, CONTAINING ANTI-VIRUS COMPOUND, IN PARTICULAR INHIBITING HIV, PHARMACEUTICAL COMPOSITION AND SET OF STANDARD DOSE OF THE MEDICINAL DRUG ON ITS BASIS, METHOD OF INHIBITING THE SOFTWARE PRO.
BRPI0409136A (en) pentacyclic heteroaromatic compound and medicinal use thereof
BRPI0307351B8 (en) compound, pharmaceutical composition, use of a compound, and, process for preparing a compound
DE60234577D1 (en) PHARMACEUTICAL MIXTURE FOR THE TREATMENT OF CANCER CONTAINING DIOXOLANE NUCLEOSIDE ANALOGUE
NO302574B1 (en) Indolcarbazolimides and their use
MA26435A1 (en) AMIDO-SUBSTITUTED BENZYLAMINE DERIVATIVES, THEIR PRECURSOR DERIVATIVES FOR MEDICAMENTS, THEIR PREPARATION PROCESSES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND TREATMENT METHOD USING THE SAME.
NO954545D0 (en) Inclusion complexes of taxol or taxotes, or taxus extract formed with cyclodextrin, as well as the preparation and use thereof
ATE361918T1 (en) 4-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA AND ITS USE IN THE TREATMENT OF GLYCOGEN SYNTHASE KINASE-3 (GSK3)-ASSOCIATED CONDITIONS
KR970705563A (en) (2-amino-6- (cyclopropylamino) -9H-purin-9-yl) -2-cyclopentene-1-methanol succinate -9H-Purin-9-yl) -2-cyclopentene-1-methanol Succinate as Antiviral Agent)
BR9809234A (en) Compound, pharmaceutical composition, use of a compound, processes to treat or prevent diseases of the endocrinological system, to manufacture a drug, to prepare a compound and a set, and use of it.
ATE234082T1 (en) MEDICINAL PRODUCT CONTAINING ADENOSINE
IL88971A (en) Disubstituted pyridines, process and intermediates, their preparation and pharmaceutical compositions containing them
AP9801286A0 (en) Therapeutic compounds.
WO1988007367A3 (en) Melatonin-derivatives for psychogenic stress and acute anxiety, and immuno-stimulant drugs
EP0328924A3 (en) Thienotriazolodiazepine compounds and pharmaceutical uses thereof
WO1990013281A3 (en) Method of suppressing hiv infection

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE FR GB IT LU NL SE

WWE Wipo information: entry into national phase

Ref document number: 1988902848

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1988902848

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1988902848

Country of ref document: EP