[go: up one dir, main page]

UY39858A - Inhibidores peptídicos bicíclicos del receptor de interleucina-23 - Google Patents

Inhibidores peptídicos bicíclicos del receptor de interleucina-23

Info

Publication number
UY39858A
UY39858A UY0001039858A UY39858A UY39858A UY 39858 A UY39858 A UY 39858A UY 0001039858 A UY0001039858 A UY 0001039858A UY 39858 A UY39858 A UY 39858A UY 39858 A UY39858 A UY 39858A
Authority
UY
Uruguay
Prior art keywords
interleukin
receptor
peptide inhibitors
bicyclic peptide
disorders
Prior art date
Application number
UY0001039858A
Other languages
English (en)
Inventor
J Patch Raymond
Chengzao Sun
A Barros Stephanie
Sandeep Somani
Charles Hendrick
Jing Zhang
Elisabetta Bianchi
Roberto Costante
Raffaele Ingenito
Danila Branca
Ashok Bhandari
Brian Frederick
Trung Tran Tran
Francis Neelamkavil Santhosh
Jie Zhang
Original Assignee
Janssen Biotech Inc
Protagonist Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc, Protagonist Therapeutics Inc filed Critical Janssen Biotech Inc
Publication of UY39858A publication Critical patent/UY39858A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)

Abstract

La presente invención se refiere a inhibidores peptídicos bicíclicos novedosos del receptor de interleucina-23 (IL-23R) o sal farmacéuticamente aceptable del mismo, composiciones farmacéuticas correspondientes, métodos y/o usos para el tratamiento de inflamación autoinmune y enfermedades y trastornos relacionados.
UY0001039858A 2021-07-14 2022-07-14 Inhibidores peptídicos bicíclicos del receptor de interleucina-23 UY39858A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202163221854P 2021-07-14 2021-07-14

Publications (1)

Publication Number Publication Date
UY39858A true UY39858A (es) 2023-02-28

Family

ID=84920518

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039858A UY39858A (es) 2021-07-14 2022-07-14 Inhibidores peptídicos bicíclicos del receptor de interleucina-23

Country Status (12)

Country Link
US (1) US20240352073A1 (es)
EP (1) EP4370532A4 (es)
JP (1) JP2024525723A (es)
KR (1) KR20240034223A (es)
CN (1) CN117980320A (es)
AR (1) AR126457A1 (es)
AU (1) AU2022310347A1 (es)
CA (1) CA3226492A1 (es)
MX (1) MX2024000761A (es)
TW (1) TW202321275A (es)
UY (1) UY39858A (es)
WO (1) WO2023288017A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2968443T3 (pl) 2013-03-15 2022-02-07 Protagonist Therapeutics, Inc. Analogi hepcydyny i ich zastosowania
CN113621027A (zh) 2014-05-16 2021-11-09 领导医疗有限公司 α4β7整联蛋白硫醚肽拮抗剂
SG10201810154WA (en) 2014-07-17 2018-12-28 Protagonist Therapeutics Inc Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
WO2019157268A1 (en) 2018-02-08 2019-08-15 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
EP4090669A4 (en) 2020-01-15 2024-11-20 Janssen Biotech, Inc. PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR AND THEIR USE IN TREATING INFLAMMATORY DISEASES
EP4247403A4 (en) 2020-11-20 2024-12-11 JANSSEN Pharmaceutica NV COMPOSITIONS OF PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR
AU2022311814A1 (en) 2021-07-14 2024-02-29 Janssen Biotech, Inc. Lipidated peptide inhibitors of interleukin-23 receptor
WO2024155551A1 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Polycyclic peptide inhibitors of interleukin-23 receptor
EP4471048A1 (en) 2023-06-01 2024-12-04 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
EP4471049A1 (en) 2023-06-01 2024-12-04 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
WO2025051920A1 (en) 2023-09-08 2025-03-13 Sanofi New peptides as selective il-23 receptor inhibitors
WO2025051912A1 (en) 2023-09-08 2025-03-13 Sanofi New peptides as selective il-23 receptor inhibitors
WO2025076414A1 (en) * 2023-10-06 2025-04-10 The Children's Medical Center Corporation Compositions and methods for selecting a subject for inflammatory bowel disease treatment

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201810154WA (en) * 2014-07-17 2018-12-28 Protagonist Therapeutics Inc Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
US10301371B2 (en) * 2014-10-01 2019-05-28 Protagonist Therapeutics, Inc. Cyclic monomer and dimer peptides having integrin antagonist activity
SG10201912066SA (en) * 2015-07-15 2020-02-27 Protagonist Therapeutics Inc Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
AU2017371472B2 (en) * 2016-12-06 2024-08-08 Universiteit Van Amsterdam Multicyclic peptides and methods for their preparation
US20200291096A1 (en) * 2017-08-14 2020-09-17 Bicyclerd Limited Bicyclic peptide ligand sting conjugates and uses thereof
CA3085337A1 (en) * 2017-12-15 2019-06-20 Janssen Biotech, Inc. Cyclic dinucleotides as sting agonists
EP3820883A4 (en) * 2018-07-12 2022-04-20 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
TW202116793A (zh) * 2019-07-10 2021-05-01 美商領導醫療有限公司 介白素-23受體之肽抑制劑及其於治療發炎疾病的用途

Also Published As

Publication number Publication date
KR20240034223A (ko) 2024-03-13
US20240352073A1 (en) 2024-10-24
AU2022310347A1 (en) 2024-02-29
WO2023288017A2 (en) 2023-01-19
AR126457A1 (es) 2023-10-11
JP2024525723A (ja) 2024-07-12
CN117980320A (zh) 2024-05-03
WO2023288017A3 (en) 2023-03-09
EP4370532A4 (en) 2025-09-03
MX2024000761A (es) 2024-04-18
CA3226492A1 (en) 2023-01-19
EP4370532A2 (en) 2024-05-22
TW202321275A (zh) 2023-06-01

Similar Documents

Publication Publication Date Title
UY39858A (es) Inhibidores peptídicos bicíclicos del receptor de interleucina-23
UY39856A (es) Inhibidores peptídicos del receptor de interleucina-23
CO2023007172A2 (es) Composiciones de inhibidores peptídicos del receptor de interleucina-23
UY39857A (es) Inhibidores peptídicos lipidados del receptor de interleucina-23
ECSP22063238A (es) Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias
MX2022008740A (es) Peptidos inhibidores del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.
AR119389A1 (es) Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias
BR112022000328A2 (pt) Inibidores peptídicos do receptor de interleucina-23 e seu uso para tratar doenças inflamatórias
MX2024009477A (es) Inhibidores peptídicos del receptor de interleucina-23 y composiciones farmacéuticas de estos
TR201816176T4 (tr) Histon deasetilaz 6 inhibitörleri olarak yeni bileşikler ve bunu içeren farmasötik bileşimler.
CO2024005925A2 (es) Moléculas pequeñas para el tratamiento del cáncer
MX2023003348A (es) Compuestos y composiciones como moduladores de señalización tlr.
ECSP19084722A (es) Compuestos bicíclicos 5,6-fusionados y composiciones para el tratamiento de enfermedades parasitarias
CO2025010249A2 (es) Inhibidores peptídicos del receptor de interleucina-23
DOP2025000151A (es) Inhibidores peptídicos del receptor de interleucina-23
WO2024155547A3 (en) Peptide inhibitors of interleukin-23 receptor
MX2022005843A (es) Derivados de bencilamida como inhibidores del receptor i del factor de crecimiento transformante beta/ cinasa similar al receptor de activina 5 (alk5).
MX2025008274A (es) Formulaciones de inhibidores peptidicos lipidados del receptor de interleucina-23
UY40134A (es) Motor de presión negativa