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UY39857A - Inhibidores peptídicos lipidados del receptor de interleucina-23 - Google Patents

Inhibidores peptídicos lipidados del receptor de interleucina-23

Info

Publication number
UY39857A
UY39857A UY0001039857A UY39857A UY39857A UY 39857 A UY39857 A UY 39857A UY 0001039857 A UY0001039857 A UY 0001039857A UY 39857 A UY39857 A UY 39857A UY 39857 A UY39857 A UY 39857A
Authority
UY
Uruguay
Prior art keywords
interleukin
receptor
peptide inhibitors
lipidated peptide
inhibitors
Prior art date
Application number
UY0001039857A
Other languages
English (en)
Inventor
J Patch Raymond
Chengzao Sun
A Barros Stephanie
Sandeep Somani
Charles Hendrick
Jing Zhang
Elisabetta Bianchi
Roberto Costante
Danila Branca
Ashok Bhandari
Brian Frederick
James Daniel
Trung Tran Tran
Francis Neelamkavil Santhosh
Douglas Riexinger
Frederica Rosolia
Martina Lollobrigida
Del Rizzo Sonja
Original Assignee
Janssen Biotech Inc
Protagonist Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc, Protagonist Therapeutics Inc filed Critical Janssen Biotech Inc
Publication of UY39857A publication Critical patent/UY39857A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a nuevos inhibidores peptídicos lipidados del receptor de interleucina-23 (IL-23R) o sales farmacéuticamente aceptables, solvatos y/u otras formas de los mismos, composiciones farmacéuticas correspondientes, métodos y/o usos de los inhibidores de IL-23R para el tratamiento de enfermedades inflamatorias autoinmunes y/o trastornos relacionados.
UY0001039857A 2021-07-14 2022-07-14 Inhibidores peptídicos lipidados del receptor de interleucina-23 UY39857A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202163221697P 2021-07-14 2021-07-14

Publications (1)

Publication Number Publication Date
UY39857A true UY39857A (es) 2023-02-28

Family

ID=84920513

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039857A UY39857A (es) 2021-07-14 2022-07-14 Inhibidores peptídicos lipidados del receptor de interleucina-23

Country Status (16)

Country Link
US (1) US12478617B2 (es)
EP (1) EP4370146A4 (es)
JP (1) JP2024525732A (es)
KR (1) KR20240034224A (es)
CN (1) CN118055773A (es)
AU (1) AU2022311814A1 (es)
CA (1) CA3226532A1 (es)
CL (1) CL2024000099A1 (es)
CO (1) CO2024000999A2 (es)
DO (1) DOP2024000011A (es)
IL (1) IL310061A (es)
MX (1) MX2024000760A (es)
PE (1) PE20240595A1 (es)
TW (1) TW202330013A (es)
UY (1) UY39857A (es)
WO (1) WO2023288019A2 (es)

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EP4090669A4 (en) 2020-01-15 2024-11-20 Janssen Biotech, Inc. PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR AND THEIR USE IN TREATING INFLAMMATORY DISEASES
EP4247403A4 (en) 2020-11-20 2024-12-11 JANSSEN Pharmaceutica NV COMPOSITIONS OF PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR
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CA3261954A1 (en) * 2022-07-14 2024-01-18 Janssen Pharmaceutica Nv IL-23 CYCLIC PEPTIDE INHIBITORS
EP4652182A1 (en) * 2023-01-16 2025-11-26 Janssen Pharmaceutica NV Peptide inhibitors of interleukin-23 receptor
WO2024155551A1 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Polycyclic peptide inhibitors of interleukin-23 receptor
WO2024155553A1 (en) 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Lipidated peptide inhibitors of interleukin-23 receptor
AU2024214418A1 (en) * 2023-01-31 2025-09-18 Janssen Pharmaceutica Nv Methods for preparing crystalline peptide inhibitors of interleukin-23 receptor
AU2024233524A1 (en) * 2023-03-03 2025-10-16 Janssen Pharmaceutica Nv Interleukin-23 receptor antagonist peptides for use in the treatment of psoriasis
EP4471048A1 (en) 2023-06-01 2024-12-04 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
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