[go: up one dir, main page]

UY33219A - Cetoenoles cíclicos para terapias - Google Patents

Cetoenoles cíclicos para terapias

Info

Publication number
UY33219A
UY33219A UY0001033219A UY33219A UY33219A UY 33219 A UY33219 A UY 33219A UY 0001033219 A UY0001033219 A UY 0001033219A UY 33219 A UY33219 A UY 33219A UY 33219 A UY33219 A UY 33219A
Authority
UY
Uruguay
Prior art keywords
therapies
cetoenols
cyclic
cyclic cetoenols
prophylaxis
Prior art date
Application number
UY0001033219A
Other languages
English (en)
Inventor
Dr Reiner Fischer
Dr Kai Thede
Dr Ningshu Liu
Dr Philip Lienau
Dr Arne Scholz
Dr Christoph-Stephan Hilger
Dr Ulf Bomer
Dr Maher Najjar
Dr Knut Eis
Dr Wahed Ahmed Moradi
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of UY33219A publication Critical patent/UY33219A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/382-Pyrrolones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54Spiro-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)

Abstract

Cetoenoles cíclicos 5´-bifenil-sustituidos para fines terapéuticos, composiciones farmacéuticas y su uso en terapias, en particular para la profilaxis y/o la terapia de trastornos tumorales.
UY0001033219A 2010-02-15 2011-02-08 Cetoenoles cíclicos para terapias UY33219A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102010008644A DE102010008644A1 (de) 2010-02-15 2010-02-15 Zyklische Ketoenole zur Therapie

Publications (1)

Publication Number Publication Date
UY33219A true UY33219A (es) 2011-09-30

Family

ID=43707823

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033219A UY33219A (es) 2010-02-15 2011-02-08 Cetoenoles cíclicos para terapias

Country Status (9)

Country Link
US (1) US20130040935A1 (es)
EP (1) EP2536686A1 (es)
JP (1) JP2013519639A (es)
CN (1) CN102844300A (es)
CA (1) CA2789551A1 (es)
DE (1) DE102010008644A1 (es)
TW (1) TW201130489A (es)
UY (1) UY33219A (es)
WO (1) WO2011098433A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5951642B2 (ja) 2011-01-25 2016-07-13 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH 1−h−ピロリジン−2,4−ジオン誘導体を製造する方法
MA34887B1 (fr) * 2011-02-06 2014-02-01 Bayer Ip Gmbh Utilisation de (5s,8s)-3-(4'-chloro-3'-fluoro-4-méthylbiphényl-3-yl)-4-hydroxy- 8-méthoxy-1-azaspiro[4.5]décane-3-en-2-one (composé a) à des fins thérapeutiques
WO2012110519A1 (de) 2011-02-17 2012-08-23 Bayer Cropscience Ag Substituierte 3-(biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur therapie und halogensubstituierte spirocyclische ketoenole
JP5987007B2 (ja) 2011-03-01 2016-09-06 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH 2−アシルオキシピロリン−4−オン類
US9211333B2 (en) 2012-06-05 2015-12-15 Hong Kong Baptist University Anti-cancer agents synthesized based on miliusane compounds
CN105530940A (zh) 2013-09-12 2016-04-27 辉瑞大药厂 乙酰辅酶a羧化酶抑制剂用于治疗寻常痤疮的用途
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
CN114409664B (zh) * 2021-12-24 2023-07-18 河北威远生物化工有限公司 一种螺杂环四氢吡喃化合物及其制备方法和应用

Family Cites Families (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104043A (en) 1972-12-12 1978-08-01 Union Carbide Corporation Esters of 3-hydroxyindone compounds as herbicides and miticides
US4659372A (en) 1977-03-28 1987-04-21 Union Carbide Corporation Biocidal 2-aryl-1,3-cyclohexanedione enol ester compounds
US4256658A (en) 1977-03-28 1981-03-17 Union Carbide Corporation Method of preparing 2-aryl-1,3-cyclohexanedione compounds
PT67818A (en) 1977-03-28 1978-04-01 Union Carbide Corp Process for the synthesis of biocidal 2-aryl-1,3-cycloalkanedionas and their enol esters
US4256659A (en) 1977-03-28 1981-03-17 Union Carbide Corporation Method of preparing 2-aryl-1,3-cyclohexanedione compounds
US4256657A (en) 1977-03-28 1981-03-17 Union Carbide Corporation Method of preparing 2-aryl-1,3-cyclohexanedione compounds
US4257858A (en) 1977-03-28 1981-03-24 Union Carbide Corporation Photochemical method for producing biocidal 2-aryl-1,3-cyclohexanedione compounds
US4175135A (en) 1978-07-18 1979-11-20 Union Carbide Corporation Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof
US4436666A (en) 1978-09-22 1984-03-13 Union Carbide Corporation Biocidal enol derivatives of 2-aryl-1,3-cycloalkanedione compounds
US4283348A (en) 1978-09-22 1981-08-11 Union Carbide Corporation Method of preparing 2-aryl-3-cyclopentanedione compounds
US4526723A (en) 1978-09-27 1985-07-02 Union Carbide Corporation Biocidal enol esters of non-ortho substituted 2-aryl-1-3-cycloalkanedione compounds
US4338122A (en) 1979-09-26 1982-07-06 Union Carbide Corporation Biocidal 2-aryl-1,3-cyclopentanedione compounds and alkali metal and ammonium salts thereof
US4303669A (en) 1980-03-25 1981-12-01 Union Carbide Corporation Hybrid 1,3-dione-carbamate compounds
US4409153A (en) 1980-03-28 1983-10-11 Union Carbide Corporation O-(2-Aryl-3-oxo-1-cyclohexenyl) phosphates
US4351666A (en) 1980-06-27 1982-09-28 Union Carbide Corporation Enol derivatives of 2-aryl-1,3-cyclohexanedione compound as sugar enhancer for plants
US4551547A (en) 1980-11-10 1985-11-05 Union Carbide Corporation Biocidal 2-aryl-1, 3-cyclopentanedione enol ester compounds
US4613617A (en) 1981-06-26 1986-09-23 Union Carbide Corporation Synergistic insecticidal compositions containing dione esters
US4632698A (en) 1983-09-02 1986-12-30 Union Carbide Corporation Biocidal 2-aryl-1,3-cyclopentanedione enol ester compounds
US4925868A (en) 1986-08-29 1990-05-15 Takeda Chemical Industries, Ltd. 4-Hydroxy-3-pyrrolin-2-ones and treatment of circulatory disorders therewith
US4985063A (en) 1988-08-20 1991-01-15 Bayer Aktiengesellschaft 3-aryl-pyrrolidine-2,4-diones
DE58907411D1 (de) 1989-01-07 1994-05-11 Bayer Ag 3-Aryl-pyrrolidin-2,4-dion-Derivate.
ATE151882T1 (de) 1989-01-17 1997-05-15 Univ Johns Hopkins Karzinomverwandtes haptoglobin (hpr)
US5759837A (en) 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5336662A (en) 1989-04-25 1994-08-09 Sandoz Ltd. Heterocyclic diones as plant growth regulators
TR24452A (tr) 1989-04-25 1991-11-01 Sandoz Ltd Pestisidler ve bitki bueyueme duezenleyicileri olarak heterosiklik dionlar
DE3929087A1 (de) 1989-09-01 1991-03-07 Bayer Ag 3-aryl-pyrrolidin-2,4-dion-derivate
DE4014420A1 (de) 1989-09-23 1991-04-04 Bayer Ag 5h-furan-2-on-derivate
DE4032090A1 (de) 1990-02-13 1991-08-14 Bayer Ag Polycyclische 3-aryl-pyrrolidin-2,4-dion-derivate
DE4004496A1 (de) 1990-02-14 1991-08-22 Bayer Ag 3-aryl-pyrrolidin-2,4-dion-derivate
DE4107394A1 (de) 1990-05-10 1991-11-14 Bayer Ag 1-h-3-aryl-pyrrolidin-2,4-dion-derivate
IL99834A0 (en) 1990-10-25 1992-08-18 Sandoz Ag Heterocyclic dione derivatives,their preparation and their use as pesticides and plant growth regulators
WO1992016510A1 (en) 1991-03-19 1992-10-01 Ciba-Geigy Ag Novel herbicidally, acaricidally and insecticidally active compounds
DE4109208A1 (de) 1991-03-21 1992-09-24 Bayer Ag 3-hydroxy-4-aryl-5-oxo-pyrazolin-derivate
DE4121365A1 (de) 1991-06-28 1993-01-14 Bayer Ag Substituierte 1-h-3-aryl-pyrrolidin-2,4-dion-derivate
DE4216814A1 (de) 1991-07-16 1993-01-21 Bayer Ag 3-aryl-4-hydroxy-(delta)(pfeil hoch)3(pfeil hoch)-dihydrofuranon- und 3-aryl-4-hydroxy-(delta)(pfeil hoch)3(pfeil hoch)-dihydrothiophenon-derivate
GB9210393D0 (en) 1992-05-15 1992-07-01 Merck Sharp & Dohme Therapeutic agents
DE4308451A1 (de) 1992-09-10 1994-04-14 Bayer Ag 3-Aryl-pyron-Derivate
DE4236400A1 (de) 1992-10-28 1994-05-05 Bayer Ag N-Phenylacetaminonitrile
AU666040B2 (en) 1992-10-28 1996-01-25 Bayer Aktiengesellschaft Substituted 1-H-3-aryl-pyrrolidine-2,4-dione derivatives
DE4243818A1 (de) 1992-12-23 1994-06-30 Bayer Ag 5-Aryl-1,3-thiazin-Derivate
DE4306257A1 (de) 1993-03-01 1994-09-08 Bayer Ag Substituierte 1-H-3-Phenyl-5-cycloalkylpyrrolidin-2,4-dione, ihre Herstellung und ihre Verwendung
DE4306259A1 (de) 1993-03-01 1994-09-08 Bayer Ag Dialkyl-1-H-3-(2,4-dimethylphenyl)-pyrrolidin-2,4-dione, ihre Herstellung und ihre Verwendung
ES2130431T3 (es) 1993-07-05 1999-07-01 Bayer Ag Aril-cetoenolheterociclos substituidos.
EP0647637B1 (de) 1993-09-17 1999-01-27 Bayer Ag 3-Aryl-4-hydroxy-3-dihydrofuranon-Derivate
ES2219457T3 (es) 1993-11-19 2004-12-01 PARKE, DAVIS & COMPANY Derivados de 5,6-dihidropironas como inhibidores de proteasa y agentes antiviricos.
DE4425617A1 (de) 1994-01-28 1995-08-03 Bayer Ag 1-H-3-Aryl-pyrrolidin-2,4-dion-Derivate
DE4431730A1 (de) 1994-02-09 1995-08-10 Bayer Ag Substituierte 1H-3-Aryl-pyrrolidin-2,4-dion-Derivate
DE4410420A1 (de) 1994-03-25 1995-09-28 Bayer Ag 3-Aryl-4-hydroxy- DELTA·3·-dihydrothiophenon-Derivate
CN1075060C (zh) 1994-04-05 2001-11-21 拜尔公司 用作除草剂和农药的烷氧基-烷基取代的1-h-3-芳基-吡咯烷-2,4-二酮
US5840661A (en) 1994-07-07 1998-11-24 Bayer Aktiengesellschaft 2-aryl cyclopentane-1,3-dione derivatives
JPH0832530A (ja) 1994-07-15 1996-02-02 Sony Corp データ放送システムおよびデータ受信装置
EP0773920B1 (de) 1994-07-21 2000-01-26 Bayer Ag 2-(2,4,6-trimethylphenyl)-cyclopentan-1,3-dion-derivate
EP0786937A2 (en) 1994-10-17 1997-08-06 Novartis AG Herbicidal compositions
JP3727680B2 (ja) 1994-11-30 2005-12-14 株式会社東芝 あいまい推論装置及びあいまい推論方法
JP3529179B2 (ja) 1994-12-16 2004-05-24 辰一 岡本 推進装置
ES2190790T3 (es) 1994-12-23 2003-08-16 Bayer Cropscience Ag Derivados del acido 3-aril-tetronico, su obtencion y su empleo como agentes pesticidas.
WO1996021652A1 (en) 1995-01-13 1996-07-18 Novartis Ag 4-aryl- and 4-heteroaryl -5-oxopyrazoline derivatives having pesticidal properties
JP4036470B2 (ja) 1995-02-13 2008-01-23 バイエル・アクチエンゲゼルシヤフト 除草剤および有害生物防除剤としての2−フェニル置換複素環式1,3−ケトエノール
BR9608229A (pt) 1995-05-09 1998-12-29 Bayer Ag Cetoenóis alquil-dihalogenofenil-substituídos
RU2195449C2 (ru) 1995-06-28 2002-12-27 Байер Акциенгезельшафт 2,4,5-тризамещенные фенилкетоенолы, промежуточные соединения для их получения, способ и средство для борьбы с насекомыми и паукообразными на их основе
ES2189877T3 (es) 1995-06-30 2003-07-16 Bayer Cropscience Ag Cetoenoles dialquil-halogenofenilsubstituidos para el empleo como herbicidas y pesticidas.
DE19538218A1 (de) 1995-10-13 1997-04-17 Bayer Ag Cyclopentan-1,3-dion-Derivate
DE19540080A1 (de) 1995-10-27 1997-04-30 Bayer Ag 3-Aryl-5-halogen-pyron-Derivate
DE19544457A1 (de) 1995-11-29 1997-06-05 Bayer Ag Oxymethoxy-3-aryl-pyron-Derivate
CA2250417A1 (en) 1996-04-02 1997-10-09 Bayer Aktiengesellschaft Substituted phenyl keto enols as pesticides and herbicides
CN1156470C (zh) 1996-05-10 2004-07-07 拜尔公司 新的取代的吡啶基酮烯醇
DK1277734T3 (da) 1996-08-05 2007-06-04 Bayer Cropscience Ag 2- og 2,5-substituerede phenylketoenoler
DE19632126A1 (de) 1996-08-09 1998-02-12 Bayer Ag Phenylsubstituierte cyclische Ketoenole
DE19651686A1 (de) 1996-12-12 1998-06-18 Bayer Ag Neue substituierte Phenylketoenole
DE19708607A1 (de) 1997-03-03 1998-09-10 Bayer Ag 2-Arylcyclopentan-1,3-dione
JP3526215B2 (ja) 1997-07-03 2004-05-10 大日本印刷株式会社 光ファイバー加工用位相マスク及びその製造方法
DE19742492A1 (de) 1997-09-26 1999-04-01 Bayer Ag Spirocyclische Phenylketoenole
DE19749720A1 (de) 1997-11-11 1999-05-12 Bayer Ag Neue substituierte Phenylketoenole
JPH11152273A (ja) 1997-11-19 1999-06-08 Otsuka Chem Co Ltd 窒素含有6員環ジオン誘導体
DE19808261A1 (de) 1998-02-27 1999-10-28 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
HU228637B1 (en) 1998-03-13 2013-04-29 Syngenta Participations Ag Herbicidally active 3-hydroxy-4-aryl-5-oxopyrazoline derivatives and use thereof
DE19813354A1 (de) * 1998-03-26 1999-09-30 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
DE19818732A1 (de) 1998-04-27 1999-10-28 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
JP2000053670A (ja) 1998-08-10 2000-02-22 Ube Ind Ltd アルコキシメチルフラノン誘導体及び有害生物防除剤
JP2002542805A (ja) 1999-04-30 2002-12-17 ユニバーシティ オブ フロリダ アデノ随伴ウイルス送達リボザイム組成物および使用方法
CA2382435C (en) 1999-09-07 2009-02-03 Syngenta Participations Ag Novel herbicidally active phenyl-substituted heterocycles
WO2001017973A2 (de) 1999-09-07 2001-03-15 Syngenta Participations Ag Neue herbizide
HU228800B1 (en) 1999-09-07 2013-05-28 Syngenta Participations Ag Synergistic herbicidal composition and use thereof
ATE253824T1 (de) 1999-09-07 2003-11-15 Syngenta Participations Ag Herbizide zusammensetzungen
DK1209973T3 (da) 1999-09-07 2004-06-21 Syngenta Participations Ag Herbicidt middel
DE19946625A1 (de) 1999-09-29 2001-04-05 Bayer Ag Trifluormethylsubstituierte spirocyclische Ketoenole
DE10016544A1 (de) 2000-04-03 2001-10-11 Bayer Ag C2-phenylsubstituierte Ketoenole
DE10019145A1 (de) 2000-04-18 2001-10-25 Bayer Ag Phenylsubstituierte 4-Hydroxy-tetrahydropyridone
JP2002205984A (ja) 2000-05-11 2002-07-23 Sankyo Co Ltd N−置換スピロジヒドロピロール誘導体
DE10030094A1 (de) 2000-06-19 2001-12-20 Bayer Ag Phenylsubstituierte 5,6-Dihydro-pyron-Derivate
ITBS20010059U1 (it) 2001-06-25 2002-12-25 Emer Srl Barra iniettori di combustibile in impianti a gas per autotrazione
DE10139465A1 (de) 2001-08-10 2003-02-20 Bayer Cropscience Ag Selektive Herbizide auf Basis von substituierten, cayclischen Ketoenolen und Safenern
PL207276B1 (pl) 2001-09-27 2010-11-30 Syngenta Participations Ag Kompozycja chwastobójcza oraz sposób selektywnego zwalczania chwastów i traw w uprawach roślin użytkowych
DE10160007A1 (de) 2001-12-06 2003-06-18 Bayer Cropscience Ag [1.2]-Oxazin-3,5-dione
HUP0402592A2 (hu) 2002-01-22 2005-04-28 Syngenta Participations Ag Herbicidekként hasznosítható fenil-szubsztituált heterociklusos vegyületek
DE10231333A1 (de) 2002-07-11 2004-01-22 Bayer Cropscience Ag Cis-Alkoxysubstituierte spirocyclische 1-H-Pyrrolidin-2,4-dion-Derivate
DE10239479A1 (de) 2002-08-28 2004-03-04 Bayer Cropscience Ag Substituierte spirocyclische Ketoenole
DE10301804A1 (de) 2003-01-20 2004-07-29 Bayer Cropscience Ag 2,4-Dihalogen-6-(C2-C3-alkyl)-phenyl substituierte Tetramsäure-Derivate
DE10311300A1 (de) 2003-03-14 2004-09-23 Bayer Cropscience Ag 2,4,6-Phenylsubstituierte cyclische Ketoenole
DE10326386A1 (de) 2003-06-12 2004-12-30 Bayer Cropscience Ag N-Heterocyclyl-phenylsubstituierte cyclische Ketoenole
DE10331675A1 (de) 2003-07-14 2005-02-10 Bayer Cropscience Ag Hetarylsubstituierte Pyrazolidindion-Derivate
DE10337497A1 (de) 2003-08-14 2005-03-10 Bayer Cropscience Ag 4-Biphenylsubstituierte-Pyrazolidin-3,5-dion-Derivate
DE10351646A1 (de) 2003-11-05 2005-06-09 Bayer Cropscience Ag 2-Halogen-6-alkyl-phenyl substituierte spirocyclische Tetramsäure-Derivate
DE10351647A1 (de) 2003-11-05 2005-06-09 Bayer Cropscience Ag 2-Halogen-6-alkyl-phenyl substituierte Tetramsäure-Derivate
DE10354628A1 (de) 2003-11-22 2005-06-16 Bayer Cropscience Ag 2-Ethyl-4,6-dimethyl-phenyl-substituierte Tetramsäure-Derivate
DE10354629A1 (de) 2003-11-22 2005-06-30 Bayer Cropscience Ag 2-Ethyl-4,6-dimethyl-phenyl substituierte spirocyclische Tetramsäure-Derivate
DE102004001433A1 (de) 2004-01-09 2005-08-18 Bayer Cropscience Ag cis-Alkoxyspiro-substituierte Tetramsäure-Derivate
US7388027B2 (en) 2004-03-04 2008-06-17 Bristol-Myers Squibb Company Bicyclic compounds as modulators of androgen receptor function and method
DE102004014620A1 (de) 2004-03-25 2005-10-06 Bayer Cropscience Ag 2,4,6-phenylsubstituierte cyclische Ketoenole
DE102004030753A1 (de) 2004-06-25 2006-01-19 Bayer Cropscience Ag 3'-Alkoxy spirocyclische Tetram- und Tretronsäuren
DE102004041529A1 (de) 2004-08-27 2006-03-02 Bayer Cropscience Gmbh Herbizid-Kombinationen mit speziellen Ketoenolen
DE102004044827A1 (de) 2004-09-16 2006-03-23 Bayer Cropscience Ag Jod-phenylsubstituierte cyclische Ketoenole
DE102004053192A1 (de) 2004-11-04 2006-05-11 Bayer Cropscience Ag 2-Alkoxy-6-alkyl-phenyl substituierte spirocyclische Tetramsäure-Derivate
DE102004053191A1 (de) 2004-11-04 2006-05-11 Bayer Cropscience Ag 2,6-Diethyl-4-methyl-phenyl substituierte Tetramsäure-Derivate
WO2006055625A2 (en) * 2004-11-18 2006-05-26 The Institutes For Pharmaceutical Discovery, Llc Heterocyclylbiphenyl derivates as protein tyrosine phosphatase inhibitors
DE102005008021A1 (de) 2005-02-22 2006-08-24 Bayer Cropscience Ag Spiroketal-substituierte cyclische Ketoenole
EP1907323B1 (de) 2005-07-16 2018-04-25 Archroma IP GmbH Verfahren zur herstellung von nanopartikeln aus aluminiumoxid und oxiden von elementen der i. und ii. hauptgruppe des periodensystems
JP2009510150A (ja) 2005-10-06 2009-03-12 ノバルティス アクチエンゲゼルシャフト Lfa−1メディエーターとしてのテトラヒドロ−ピロリジノン化合物
DE102005051325A1 (de) 2005-10-27 2007-05-03 Bayer Cropscience Ag Alkoxyalkyl spirocyclische Tetram- und Tetronsäuren
DE102005059892A1 (de) 2005-12-15 2007-06-28 Bayer Cropscience Ag Alkylthio-spirocyclische Tetramsäuren
DE102005059891A1 (de) 2005-12-15 2007-06-28 Bayer Cropscience Ag 3'-Alkoxy-spirocyclopentyl substituierte Tetram- und Tetronsäuren
DE102006000971A1 (de) 2006-01-07 2007-07-12 Bayer Cropscience Ag 2,4,6-Trialkylphenylsubstituierte Cyclopentan-1,3-dione
DE102006007882A1 (de) 2006-02-21 2007-08-30 Bayer Cropscience Ag Cycloalkyl-phenylsubstituierte cyclische Ketoenole
DE102006018828A1 (de) 2006-04-22 2007-10-25 Bayer Cropscience Ag Alkoxyalkyl-substituierte cyclische Ketoenole
DE102006025874A1 (de) 2006-06-02 2007-12-06 Bayer Cropscience Ag Alkoxyalkyl-substituierte cyclische Ketoenole
DE102006039912A1 (de) 2006-08-25 2008-03-20 Bayer Healthcare Ag Substituierte Spirotetronsäuren und ihre Verwendung
DE102006050148A1 (de) 2006-10-25 2008-04-30 Bayer Cropscience Ag Trifluormethoxy-phenylsubstituierte Tetramsäure-Derivate
DE102006057036A1 (de) 2006-12-04 2008-06-05 Bayer Cropscience Ag Biphenylsubstituierte spirocyclische Ketoenole
DE102006057037A1 (de) 2006-12-04 2008-06-05 Bayer Cropscience Ag cis-Alkoxyspirocyclische biphenylsubstituierte Tetramsäure-Derivate
NZ577571A (en) 2006-12-14 2012-03-30 Syngenta Participations Ag 4-phenyl-pyrane-3,5-diones, 4-phenyl-thiopyrane-3,5-diones and cyclohexanetriones as novel herbicides
DE102007001866A1 (de) 2007-01-12 2008-07-17 Bayer Cropscience Ag Spirocyclische Tetronsäure-Derivate
GB0704653D0 (en) 2007-03-09 2007-04-18 Syngenta Participations Ag Novel herbicides
GB0704652D0 (en) 2007-03-09 2007-04-18 Syngenta Participations Ag Novel herbicides
EP1992614A1 (de) 2007-05-16 2008-11-19 Bayer CropScience Aktiengesellschaft 3-(2-Alkoxy-phenyl)-substituierte Tetramate
GB0710223D0 (en) 2007-05-29 2007-07-11 Syngenta Ltd Novel Herbicides
CN102084554B (zh) 2007-07-31 2013-12-04 菲尼克斯电气公司 接线盒
EP2020413A1 (de) 2007-08-02 2009-02-04 Bayer CropScience AG Oxaspirocyclische-spiro-substituierte Tetram- und Tetronsäure-Derivate
GB0715454D0 (en) 2007-08-08 2007-09-19 Syngenta Ltd Novel herbicides
GB0715576D0 (en) 2007-08-09 2007-09-19 Syngenta Ltd Novel herbicides
EP2045240A1 (de) * 2007-09-25 2009-04-08 Bayer CropScience AG Halogenalkoxyspirocyclische Tetram- und Tetronsäure-Derivate
GB0720126D0 (en) 2007-10-15 2007-11-28 Syngenta Participations Ag Chemical compounds
NZ585790A (en) 2007-12-13 2012-02-24 Syngenta Ltd 4-Phenylpyrane-3,5-diones, 4-phenylthiopyrane-3,5-diones and 2-phenylcyclohexane-1,3,5-triones as herbicides
EP2103615A1 (de) 2008-03-19 2009-09-23 Bayer CropScience AG 4'4'-Dioxaspiro-spirocyclisch substituierte Tetramate
GB0812310D0 (en) 2008-07-03 2008-08-13 Syngenta Ltd Novel herbicides
GB0819205D0 (en) 2008-10-20 2008-11-26 Syngenta Ltd Novel herbicides
GB0820344D0 (en) 2008-11-06 2008-12-17 Syngenta Ltd Herbicidal compositions
GB0821167D0 (en) 2008-11-19 2008-12-24 Syngenta Ltd Novel herbicides
US8389443B2 (en) 2008-12-02 2013-03-05 Bayer Cropscience Ag Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives
TW201031335A (en) 2008-12-02 2010-09-01 Syngenta Participations Ag Chemical compounds
TWI396627B (zh) 2008-12-05 2013-05-21 Bobst Sa 在用於處理平板元件之機器中的校準方法
GB0822834D0 (en) 2008-12-15 2009-01-21 Syngenta Ltd Novel herbicides
GB0900641D0 (en) 2009-01-15 2009-02-25 Syngenta Ltd Novel herbicides
GB0900864D0 (en) 2009-01-19 2009-03-04 Syngenta Ltd Novel Herbicides
GB0901086D0 (en) 2009-01-22 2009-03-11 Syngenta Ltd Novel herbicides
GB0901835D0 (en) 2009-02-04 2009-03-11 Syngenta Ltd Novel herbicides
GB0901834D0 (en) 2009-02-04 2009-03-11 Syngenta Ltd Novel herbicides
CN103641709B (zh) 2009-03-11 2017-08-25 拜耳知识产权有限责任公司 被卤代烷基亚甲基氧基苯基取代的酮烯醇
EP2429979A1 (en) 2009-05-16 2012-03-21 Syngenta Limited Novel herbicides

Also Published As

Publication number Publication date
US20130040935A1 (en) 2013-02-14
CN102844300A (zh) 2012-12-26
JP2013519639A (ja) 2013-05-30
CA2789551A1 (en) 2011-08-18
WO2011098433A1 (de) 2011-08-18
TW201130489A (en) 2011-09-16
DE102010008644A1 (de) 2011-08-18
EP2536686A1 (de) 2012-12-26

Similar Documents

Publication Publication Date Title
SG10201808102WA (en) Bicyclic heterocycle compounds and their uses in therapy
IN2012DN06720A (es)
AU2012253759A8 (en) Tricyclic sulfonamide compounds and methods of making and using same
MX2013011908A (es) Composiciones y usos terapeuticos de inhibidores de cinasa epsilon relacionados con cinasa i-kappa b (ikk) y cinasa 1 de union tank.
PH12015500940A1 (en) Bruton`s tyrosine kinase inhibitors
AU2012253757A8 (en) Partially saturated tricyclic compounds and methods of making and using same
PH12015501067A1 (en) Pyrrolopyrimidine compounds as kinase inhibitors
PH12016500575A1 (en) Inhibitors of bruton`s tyrosine kinase
PH12014501815A1 (en) Purinone compounds as kinase inhibitors
AU2011328009A8 (en) Compounds and methods for treating pain
UY33219A (es) Cetoenoles cíclicos para terapias
EA201390803A1 (ru) Ингибиторы бромодомена и их применение
MX2014008705A (es) Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos.
MX2014008706A (es) Compuestos tricíclicos de sulfonamida y métodos para elaborarlos y usarlos.
MX343688B (es) Compuestos tricíclicos de sulfonamida y pirazolo y métodos para su fabricación y uso.
MX339201B (es) Compuestos de sulfonamida y métodos para elaborarlos y usarlos.
WO2015009726A3 (en) Medical uses of cd38 agonists
UA107550C2 (uk) Похідні естра-1,3,5(10),16-тетраєн-3-карбоксаміду, способи їх одержання, фармацевтичні препарати, що їх містять, та їх застосування для виготовлення лікарських засобів
CR20140063A (es) 3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-onas sustituidas
BR112014027981A2 (pt) compostos do tipo fumagilol e métodos de produção e utilização dos mesmos
IN2015MN00001A (es)
CY1116234T1 (el) Υποκατεστημενα 2-οξυ-κινολινο-3-καρβοξαμιδια σαν διαμορφωτες kcnq2/3
GB201302343D0 (en) Pharmaceutical compositions comprising 15-OHEPA and methods for using the same
MX2015005732A (es) Compuestos tricíclicos y métodos para hacer y utilizar los mismos.
TR201905218T4 (tr) Nörodejenerati̇f hastaliklarin tedavi̇si̇ i̇çi̇n yararli vi̇tanoli̇dler.

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20191212