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UY30247A1 - IMPROVEMENTS IN THE PREPARATION OF INTERMEDIATES THAT CONDUCT HYDROCLORIDE OF (4- (5-AMINOMETIL-2-FLUORO-PHENYL) -PIPERIDIN - 1-IL) - (4-BROMO-3-METIL-5-PROPOXI-TIOFEN-2 -IL) -METANONA. - Google Patents

IMPROVEMENTS IN THE PREPARATION OF INTERMEDIATES THAT CONDUCT HYDROCLORIDE OF (4- (5-AMINOMETIL-2-FLUORO-PHENYL) -PIPERIDIN - 1-IL) - (4-BROMO-3-METIL-5-PROPOXI-TIOFEN-2 -IL) -METANONA.

Info

Publication number
UY30247A1
UY30247A1 UY30247A UY30247A UY30247A1 UY 30247 A1 UY30247 A1 UY 30247A1 UY 30247 A UY30247 A UY 30247A UY 30247 A UY30247 A UY 30247A UY 30247 A1 UY30247 A1 UY 30247A1
Authority
UY
Uruguay
Prior art keywords
preparation
intermediates
metanona
aminometil
tiofen
Prior art date
Application number
UY30247A
Other languages
Spanish (es)
Inventor
Adam W Sledeski
Original Assignee
Sanofi Aventis Us Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Us Llc filed Critical Sanofi Aventis Us Llc
Publication of UY30247A1 publication Critical patent/UY30247A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/22Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La presente invencion se dirige a mejoras en la preparacion de compuestos de formula 7,8 y 13, que son intermedios utiles para la preparacion del compuesto de formula I.The present invention is directed to improvements in the preparation of compounds of formula 7,8 and 13, which are useful intermediates for the preparation of the compound of formula I.

UY30247A 2006-03-29 2007-03-29 IMPROVEMENTS IN THE PREPARATION OF INTERMEDIATES THAT CONDUCT HYDROCLORIDE OF (4- (5-AMINOMETIL-2-FLUORO-PHENYL) -PIPERIDIN - 1-IL) - (4-BROMO-3-METIL-5-PROPOXI-TIOFEN-2 -IL) -METANONA. UY30247A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74390806P 2006-03-29 2006-03-29

Publications (1)

Publication Number Publication Date
UY30247A1 true UY30247A1 (en) 2007-11-30

Family

ID=38283355

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30247A UY30247A1 (en) 2006-03-29 2007-03-29 IMPROVEMENTS IN THE PREPARATION OF INTERMEDIATES THAT CONDUCT HYDROCLORIDE OF (4- (5-AMINOMETIL-2-FLUORO-PHENYL) -PIPERIDIN - 1-IL) - (4-BROMO-3-METIL-5-PROPOXI-TIOFEN-2 -IL) -METANONA.

Country Status (8)

Country Link
EP (1) EP2001839A1 (en)
CN (1) CN101405262A (en)
AR (1) AR060181A1 (en)
MX (1) MX2008011259A (en)
PE (1) PE20071148A1 (en)
TW (1) TW200811093A (en)
UY (1) UY30247A1 (en)
WO (1) WO2007118010A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2005000039A (en) * 2004-03-26 2005-10-31 Aventis Pharma Inc HYDROCHLORIDE OF [4- (5-AMINOMETIL-2-FLUORO-PHENYL) - PIPERIDIN-1-IL] - (4-BOMO-3-METHYL-5-PROPOXI-TIOFEN-2-IL) -METANONE AS AN INHIBITOR OF THE MASTOCYT TRIPTASE

Also Published As

Publication number Publication date
AR060181A1 (en) 2008-05-28
WO2007118010A1 (en) 2007-10-18
CN101405262A (en) 2009-04-08
MX2008011259A (en) 2008-09-10
TW200811093A (en) 2008-03-01
EP2001839A1 (en) 2008-12-17
PE20071148A1 (en) 2007-12-10

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20130206