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UY30506A1 - Derivados de indol - Google Patents

Derivados de indol

Info

Publication number
UY30506A1
UY30506A1 UY30506A UY30506A UY30506A1 UY 30506 A1 UY30506 A1 UY 30506A1 UY 30506 A UY30506 A UY 30506A UY 30506 A UY30506 A UY 30506A UY 30506 A1 UY30506 A1 UY 30506A1
Authority
UY
Uruguay
Prior art keywords
fluorine
formula
indol derivatives
derivatives
indol
Prior art date
Application number
UY30506A
Other languages
English (en)
Inventor
Shigeki Sakamaki
Sumihiro Nomura
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38515468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30506(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of UY30506A1 publication Critical patent/UY30506A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Nuevos derivados de indol de la formula (I) o una de sus sales farmacéuticamente aceptables: en donde R1 es fluor o cloro, y R2 es hidrogeno o fluor. Los compuestos de la formula (I) son inhibidores de SGLT y son de utilidad para el tratamiento o la prevencion de diabetes y condiciones relacionadas.
UY30506A 2006-07-27 2007-07-25 Derivados de indol UY30506A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82060406P 2006-07-27 2006-07-27
US88617807P 2007-01-23 2007-01-23

Publications (1)

Publication Number Publication Date
UY30506A1 true UY30506A1 (es) 2008-01-31

Family

ID=38515468

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30506A UY30506A1 (es) 2006-07-27 2007-07-25 Derivados de indol

Country Status (31)

Country Link
US (1) US7851617B2 (es)
EP (1) EP2049557B1 (es)
JP (1) JP5102294B2 (es)
KR (1) KR101179312B1 (es)
CN (1) CN101501053B (es)
AR (1) AR062111A1 (es)
AT (1) ATE501159T1 (es)
AU (1) AU2007277662B2 (es)
BR (1) BRPI0715369A2 (es)
CA (1) CA2658116C (es)
CL (1) CL2007002197A1 (es)
CO (1) CO6150170A2 (es)
CR (1) CR10583A (es)
DE (1) DE602007013056D1 (es)
DK (1) DK2049557T3 (es)
EA (1) EA016819B1 (es)
GT (1) GT200900014A (es)
HN (1) HN2009000161A (es)
IL (1) IL196267A0 (es)
JO (1) JO2681B1 (es)
MX (1) MX2009000995A (es)
MY (1) MY145106A (es)
NO (1) NO20085337L (es)
NZ (1) NZ574072A (es)
PE (1) PE20080522A1 (es)
PL (1) PL2049557T3 (es)
PT (1) PT2049557E (es)
TW (1) TWI418556B (es)
UA (1) UA92100C2 (es)
UY (1) UY30506A1 (es)
WO (1) WO2008013322A1 (es)

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TWI542596B (zh) 2011-05-09 2016-07-21 健生藥品公司 （２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體
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Also Published As

Publication number Publication date
CL2007002197A1 (es) 2008-02-15
PE20080522A1 (es) 2008-06-13
JP2009544693A (ja) 2009-12-17
TWI418556B (zh) 2013-12-11
JP5102294B2 (ja) 2012-12-19
TW200811149A (en) 2008-03-01
HN2009000161A (es) 2011-05-25
AU2007277662A1 (en) 2008-01-31
EP2049557B1 (en) 2011-03-09
KR101179312B1 (ko) 2012-09-03
UA92100C2 (uk) 2010-09-27
ATE501159T1 (de) 2011-03-15
KR20090040356A (ko) 2009-04-23
GT200900014A (es) 2010-02-09
CO6150170A2 (es) 2010-04-20
EP2049557A1 (en) 2009-04-22
MY145106A (en) 2011-12-30
IL196267A0 (en) 2009-09-22
EA200970161A1 (ru) 2009-06-30
NZ574072A (en) 2011-05-27
CR10583A (es) 2009-06-05
EA016819B1 (ru) 2012-07-30
US7851617B2 (en) 2010-12-14
US20080027122A1 (en) 2008-01-31
JO2681B1 (en) 2013-03-03
AU2007277662B2 (en) 2011-02-03
CN101501053A (zh) 2009-08-05
WO2008013322A1 (en) 2008-01-31
PT2049557E (pt) 2011-05-05
AR062111A1 (es) 2008-10-15
DK2049557T3 (da) 2011-06-14
PL2049557T3 (pl) 2011-07-29
MX2009000995A (es) 2009-02-04
DE602007013056D1 (de) 2011-04-21
CN101501053B (zh) 2012-10-03
CA2658116A1 (en) 2008-01-31
NO20085337L (no) 2009-04-24
CA2658116C (en) 2011-07-19
BRPI0715369A2 (pt) 2013-06-18

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