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UY30454A1 - Moduladores tiazolopirimidina de trpv1 - Google Patents

Moduladores tiazolopirimidina de trpv1

Info

Publication number
UY30454A1
UY30454A1 UY30454A UY30454A UY30454A1 UY 30454 A1 UY30454 A1 UY 30454A1 UY 30454 A UY30454 A UY 30454A UY 30454 A UY30454 A UY 30454A UY 30454 A1 UY30454 A1 UY 30454A1
Authority
UY
Uruguay
Prior art keywords
trpv1
modulators
thiazolopirimidine
compounds
pruritus
Prior art date
Application number
UY30454A
Other languages
English (en)
Inventor
Alec D Lebsack
James Guy Breitenbucher
Bryan James Branstetter
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38740251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30454(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of UY30454A1 publication Critical patent/UY30454A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se describen ciertos compuestos de tiazolopirimidina, los cuales son utiles como moduladores de TRPV1. Dichos compuestos se pueden usar en composiciones farmacéuticas y mctodos para el tratamiento de estados patologicos, trastornos y afecciones mediadas por TRPV1, tales como dolor, artritis, prurito, tos, asma o enfermedad de intestino inflamatoria.
UY30454A 2006-06-30 2007-07-02 Moduladores tiazolopirimidina de trpv1 UY30454A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81815306P 2006-06-30 2006-06-30

Publications (1)

Publication Number Publication Date
UY30454A1 true UY30454A1 (es) 2008-01-31

Family

ID=38740251

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30454A UY30454A1 (es) 2006-06-30 2007-07-02 Moduladores tiazolopirimidina de trpv1

Country Status (8)

Country Link
US (1) US20080004253A1 (es)
EP (1) EP2044086A2 (es)
AR (1) AR061761A1 (es)
CL (1) CL2007001921A1 (es)
PE (1) PE20080348A1 (es)
TW (1) TW200821320A (es)
UY (1) UY30454A1 (es)
WO (1) WO2008005303A2 (es)

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US20090156598A1 (en) * 2007-12-17 2009-06-18 Lebsack Alec D Imidazolopyrimidine modulators of TRPV1
US8288397B2 (en) 2007-12-17 2012-10-16 Janssen Pharmaceutica Nv Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1
EP2562166B1 (en) * 2008-01-22 2015-08-19 Dow AgroSciences LLC 5-fluoro pyrimidine derivatives as fungicides
WO2010093704A1 (en) * 2009-02-10 2010-08-19 Abbott Laboratories Agonists and antagonists of the s1p5 receptor, and methods of uses thereof
CA2754890C (en) 2009-03-13 2018-01-16 Piet Herdewijn Bicyclic heterocycles
CN102482278B (zh) 2009-06-29 2015-04-22 因塞特公司 作为pi3k抑制剂的嘧啶酮类
UA106889C2 (uk) * 2009-08-07 2014-10-27 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні n1-ацил-5-фторпіримідинону
PL2462134T3 (pl) 2009-08-07 2014-10-31 Adama Makhteshim Ltd Pochodne n1-sulfonylo-5-fluoropirymidynonu
UA107671C2 (en) * 2009-08-07 2015-02-10 Dow Agrosciences Llc N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives
UA112284C2 (uk) * 2009-08-07 2016-08-25 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні 5-фторпіримідинону
US8759359B2 (en) 2009-12-18 2014-06-24 Incyte Corporation Substituted heteroaryl fused derivatives as PI3K inhibitors
CN102791135B (zh) * 2010-01-07 2015-05-20 陶氏益农公司 噻唑并[5,4-d]嘧啶以及它们作为农用化学品的用途
EP2558463A1 (en) 2010-04-14 2013-02-20 Incyte Corporation Fused derivatives as i3 inhibitors
GB201012889D0 (en) 2010-08-02 2010-09-15 Univ Leuven Kath Antiviral activity of novel bicyclic heterocycles
WO2011163195A1 (en) 2010-06-21 2011-12-29 Incyte Corporation Fused pyrrole derivatives as pi3k inhibitors
GB201015411D0 (en) 2010-09-15 2010-10-27 Univ Leuven Kath Anti-cancer activity of novel bicyclic heterocycles
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WO2012125629A1 (en) 2011-03-14 2012-09-20 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
JP6027611B2 (ja) 2011-07-19 2016-11-16 インフィニティー ファーマシューティカルズ， インコーポレイテッド 複素環式化合物及びその使用
HRP20171776T1 (hr) 2011-08-17 2018-01-26 Adama Makhteshim Ltd. 1-supstituirani-5-fluoro-3,6-dihidro-6-imino-2(1h)-pirimidinonski derivati kao fungicidni agensi za uporabu u zaštiti bilja
EP3196202B1 (en) 2011-09-02 2019-02-27 Incyte Holdings Corporation Heterocyclylamines as pi3k inhibitors
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
DK2938194T3 (da) 2012-12-28 2020-01-02 Adama Makhteshim Ltd N-(substituerede)-5-fluor-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidin-1 (2h)-carboxylatderivater
MX2015008443A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de 1-(benzoilo-sustituido) -5-fluoro-4-imino-3-metil-3, 4-dihidropirimidin-2 (1h)-ona.
JP6258969B2 (ja) 2012-12-28 2018-01-10 アダマ・マクテシム・リミテッド Ｎ−（置換）−５−フルオロ−４−イミノ−３−メチル−２−オキソ−３，４−ジヒドロピリミジン−１（２ｈ）−カルボキサミド誘導体
AU2013370494B2 (en) 2012-12-31 2017-08-17 Adama Makhteshim Ltd. 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1H)-one derivatives as fungicides
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HRP20251086T1 (hr) 2013-12-31 2025-11-07 Adama Makhteshim Ltd Sinergističke fungicidne smjese za kontrolu gljivičnih bolesti u žitaricama
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Also Published As

Publication number Publication date
WO2008005303A2 (en) 2008-01-10
AR061761A1 (es) 2008-09-17
EP2044086A2 (en) 2009-04-08
WO2008005303A3 (en) 2008-04-10
US20080004253A1 (en) 2008-01-03
TW200821320A (en) 2008-05-16
CL2007001921A1 (es) 2008-03-14
PE20080348A1 (es) 2008-04-25

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