UY29832A1 - Derivados de 2-aminotiazoles y 2-aminooxazoles, procesos para su preparación y su uso como compuestos farmacéuticos. - Google Patents
Derivados de 2-aminotiazoles y 2-aminooxazoles, procesos para su preparación y su uso como compuestos farmacéuticos.Info
- Publication number
- UY29832A1 UY29832A1 UY29832A UY29832A UY29832A1 UY 29832 A1 UY29832 A1 UY 29832A1 UY 29832 A UY29832 A UY 29832A UY 29832 A UY29832 A UY 29832A UY 29832 A1 UY29832 A1 UY 29832A1
- Authority
- UY
- Uruguay
- Prior art keywords
- disorders
- aminooxazoles
- derivatives
- processes
- aminotiazoles
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- ACTKAGSPIFDCMF-UHFFFAOYSA-N 1,3-oxazol-2-amine Chemical class NC1=NC=CO1 ACTKAGSPIFDCMF-UHFFFAOYSA-N 0.000 abstract 1
- RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 abstract 1
- 208000016192 Demyelinating disease Diseases 0.000 abstract 1
- 206010012305 Demyelination Diseases 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 108010015181 PPAR delta Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Derivados de 2-aminotiazoles y 2-aminooxazoles en todas sus formas estereoisoméricas, formas enantioméricas y mezclas en cualquier relación, y sus sales fisiológicamente aceptables y formas tautoméricas que muestran actividad agonistas de PPARdelta, sus sales fisiológicamente aceptables, y procesos para sus preparaciones. Los compuestos son adecuados para el tratamiento y/o prevención de trastornos de metabolismo de ácidos grasos y trastornos de utilización de la glucosa así como de trastornos en los que está implicada la resistencia a la insulina y la desmielinización y otros trastornos neutodegenerativos del sistema nervioso central y periférico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05021279 | 2005-09-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY29832A1 true UY29832A1 (es) | 2007-04-30 |
Family
ID=35764446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY29832A UY29832A1 (es) | 2005-09-29 | 2006-09-29 | Derivados de 2-aminotiazoles y 2-aminooxazoles, procesos para su preparación y su uso como compuestos farmacéuticos. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7655679B2 (es) |
| EP (1) | EP1931659B1 (es) |
| JP (1) | JP2009509987A (es) |
| KR (1) | KR20080048510A (es) |
| CN (1) | CN101277953A (es) |
| AR (1) | AR056542A1 (es) |
| AT (1) | ATE480536T1 (es) |
| AU (1) | AU2006299090A1 (es) |
| BR (1) | BRPI0616477A2 (es) |
| CA (1) | CA2624100A1 (es) |
| DE (1) | DE602006016830D1 (es) |
| IL (1) | IL190230A0 (es) |
| MA (1) | MA29806B1 (es) |
| MY (1) | MY148883A (es) |
| NO (1) | NO20081368L (es) |
| NZ (1) | NZ566876A (es) |
| RU (1) | RU2008112199A (es) |
| TW (1) | TW200732328A (es) |
| UY (1) | UY29832A1 (es) |
| WO (1) | WO2007039176A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0820400A2 (pt) | 2007-11-20 | 2015-05-19 | Sumitomo Chemical Co | Composto de piridina, composição pesticida e método de controle de pragas. |
| US9073881B2 (en) | 2011-09-23 | 2015-07-07 | Hoffmann-La Roche Inc. | Benzoic acid derivatives |
| WO2013066839A2 (en) * | 2011-10-31 | 2013-05-10 | Glaxosmithkline Llc | Compounds and methods |
| EP3976053A4 (en) * | 2019-05-31 | 2022-11-23 | Avolynt | COMPOSITIONS AND METHODS OF TREATING A METABOLIC DISEASE |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641796A (en) | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
| GB9919413D0 (en) | 1999-08-18 | 1999-10-20 | Zeneca Ltd | Chemical compounds |
| AU2003224632A1 (en) * | 2002-03-01 | 2003-09-16 | Smithkline Beecham Corporation | Hppars activators |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| EP1586573B1 (en) | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
-
2006
- 2006-09-26 AU AU2006299090A patent/AU2006299090A1/en not_active Abandoned
- 2006-09-26 KR KR1020087007472A patent/KR20080048510A/ko not_active Withdrawn
- 2006-09-26 WO PCT/EP2006/009302 patent/WO2007039176A1/en not_active Ceased
- 2006-09-26 JP JP2008532646A patent/JP2009509987A/ja not_active Abandoned
- 2006-09-26 EP EP06792250A patent/EP1931659B1/en active Active
- 2006-09-26 RU RU2008112199/04A patent/RU2008112199A/ru not_active Application Discontinuation
- 2006-09-26 CN CNA2006800360458A patent/CN101277953A/zh active Pending
- 2006-09-26 BR BRPI0616477-3A patent/BRPI0616477A2/pt not_active IP Right Cessation
- 2006-09-26 AT AT06792250T patent/ATE480536T1/de not_active IP Right Cessation
- 2006-09-26 CA CA002624100A patent/CA2624100A1/en not_active Abandoned
- 2006-09-26 DE DE602006016830T patent/DE602006016830D1/de active Active
- 2006-09-26 NZ NZ566876A patent/NZ566876A/en not_active IP Right Cessation
- 2006-09-27 MY MYPI20064226A patent/MY148883A/en unknown
- 2006-09-27 AR ARP060104224A patent/AR056542A1/es not_active Application Discontinuation
- 2006-09-27 TW TW095135659A patent/TW200732328A/zh unknown
- 2006-09-29 UY UY29832A patent/UY29832A1/es not_active Application Discontinuation
-
2008
- 2008-03-14 NO NO20081368A patent/NO20081368L/no not_active Application Discontinuation
- 2008-03-17 IL IL190230A patent/IL190230A0/en unknown
- 2008-03-24 MA MA30782A patent/MA29806B1/fr unknown
- 2008-03-26 US US12/055,771 patent/US7655679B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1931659A1 (en) | 2008-06-18 |
| NZ566876A (en) | 2010-05-28 |
| ATE480536T1 (de) | 2010-09-15 |
| WO2007039176A1 (en) | 2007-04-12 |
| KR20080048510A (ko) | 2008-06-02 |
| RU2008112199A (ru) | 2009-10-10 |
| MA29806B1 (fr) | 2008-09-01 |
| DE602006016830D1 (de) | 2010-10-21 |
| US7655679B2 (en) | 2010-02-02 |
| CA2624100A1 (en) | 2007-04-12 |
| BRPI0616477A2 (pt) | 2011-06-21 |
| US20080227834A1 (en) | 2008-09-18 |
| MY148883A (en) | 2013-06-14 |
| NO20081368L (no) | 2008-06-18 |
| CN101277953A (zh) | 2008-10-01 |
| EP1931659B1 (en) | 2010-09-08 |
| JP2009509987A (ja) | 2009-03-12 |
| AR056542A1 (es) | 2007-10-10 |
| TW200732328A (en) | 2007-09-01 |
| AU2006299090A1 (en) | 2007-04-12 |
| IL190230A0 (en) | 2008-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20130128 |