[go: up one dir, main page]

UY28258A1 - Tratamiento terapeutico - Google Patents

Tratamiento terapeutico

Info

Publication number
UY28258A1
UY28258A1 UY28258A UY28258A UY28258A1 UY 28258 A1 UY28258 A1 UY 28258A1 UY 28258 A UY28258 A UY 28258A UY 28258 A UY28258 A UY 28258A UY 28258 A1 UY28258 A1 UY 28258A1
Authority
UY
Uruguay
Prior art keywords
therapeutic treatment
treatment
constipation
prophylaxis
man
Prior art date
Application number
UY28258A
Other languages
English (en)
Inventor
Hasse Roaland Abrahamssom
Per-Goran Gillberg
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9956272&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY28258(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY28258A1 publication Critical patent/UY28258A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Se describe el uso de un inhibidor del IBAT en el tratamiento y/o profilaxix de la constipación en un animal de sangre caliente, como el hombre.
UY28258A 2003-04-05 2004-04-05 Tratamiento terapeutico UY28258A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0307918.3A GB0307918D0 (en) 2003-04-05 2003-04-05 Therapeutic use

Publications (1)

Publication Number Publication Date
UY28258A1 true UY28258A1 (es) 2004-11-30

Family

ID=9956272

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28258A UY28258A1 (es) 2003-04-05 2004-04-05 Tratamiento terapeutico

Country Status (32)

Country Link
US (1) US7514421B2 (es)
EP (2) EP1894564B1 (es)
JP (2) JP4870552B2 (es)
KR (1) KR101321577B1 (es)
CN (1) CN100366241C (es)
AR (1) AR043985A1 (es)
AT (2) ATE513550T1 (es)
AU (1) AU2004228731B2 (es)
BR (1) BRPI0408858A (es)
CA (1) CA2520109C (es)
CO (1) CO5640076A2 (es)
CY (2) CY1107424T1 (es)
DE (1) DE602004012079T2 (es)
DK (2) DK1610770T3 (es)
ES (2) ES2299832T3 (es)
GB (1) GB0307918D0 (es)
IL (1) IL170913A (es)
IS (1) IS8113A (es)
MX (1) MXPA05010706A (es)
MY (1) MY137757A (es)
NO (1) NO335140B1 (es)
NZ (1) NZ542835A (es)
PL (2) PL1610770T3 (es)
PT (2) PT1610770E (es)
RU (2) RU2342928C2 (es)
SA (1) SA04250066B1 (es)
SI (2) SI1610770T1 (es)
TW (1) TWI338577B (es)
UA (1) UA84141C2 (es)
UY (1) UY28258A1 (es)
WO (1) WO2004089350A1 (es)
ZA (1) ZA200507996B (es)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG26979A (en) 2000-12-21 2015-03-01 Astrazeneca Ab Chemical compounds
GB0121337D0 (en) 2001-09-04 2001-10-24 Astrazeneca Ab Chemical compounds
GB0121621D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
GB0121622D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
ES2278045T3 (es) 2001-09-08 2007-08-01 Astrazeneca Ab Derivados benzotiazepinicos y benzotiadiazepinicos con actividad inhibidora del transporte de acidos biliares del ileon (ibat) para el tratamiento de hiperlipidemia.
GB0209467D0 (en) 2002-04-25 2002-06-05 Astrazeneca Ab Chemical compounds
GB0213669D0 (en) 2002-06-14 2002-07-24 Astrazeneca Ab Chemical compounds
GB0304194D0 (en) 2003-02-25 2003-03-26 Astrazeneca Ab Chemical compounds
GB0307918D0 (en) * 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
AR057828A1 (es) * 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
PL2125711T3 (pl) * 2007-03-08 2014-05-30 Albireo Ab Pochodne kwasy 3-fenylopropionowego oraz ich zastosowanie w leczeniu nieswoistego zapalenia jelit
WO2010062861A2 (en) 2008-11-26 2010-06-03 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of obesity and diabetes
ES2552657T3 (es) 2010-05-26 2015-12-01 Satiogen Pharmaceuticals, Inc. Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias
LT3400944T (lt) 2010-11-04 2020-09-25 Albireo Ab Ibat inhibitoriai, skirt kepenų ligų gydymui
SG10201406155QA (en) 2011-10-28 2014-11-27 Lumena Pharmaceuticals Inc Bile Acid Recycling Inhibitors For Treatment Of Pediatric Cholestatic Liver Diseases
SG11201401849QA (en) 2011-10-28 2014-05-29 Lumena Pharmaceuticals Inc Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
RU2015139731A (ru) 2013-03-15 2017-04-20 ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи Ингибиторы рециркуляции желчных кислот для лечения первичного склерозирующего холангита и воспалительного заболевания кишечника
CN105228615A (zh) 2013-03-15 2016-01-06 鲁美纳医药公司 用于治疗巴雷特食管和胃食管返流疾病的胆汁酸再循环抑制剂
JO3301B1 (ar) 2013-04-26 2018-09-16 Albireo Ab تعديلات بلورية على إيلوبيكسيبات
KR101420315B1 (ko) * 2014-03-19 2014-07-17 남봉길 약학적 액제 조성물
US20170143738A1 (en) * 2014-06-25 2017-05-25 Ea Pharma Co., Ltd. Solid formulation and method for stabilizing the same
KR102560954B1 (ko) 2014-06-25 2023-07-31 이에이 파마 가부시키가이샤 고형 제제 및 그의 착색 방지 또는 착색 감소 방법
EP3012252A1 (en) 2014-10-24 2016-04-27 Ferring BV Crystal modifications of elobixibat
CN109310774A (zh) 2015-08-17 2019-02-05 费林股份公司 含有匹可硫酸盐和柠檬酸镁的液体制剂
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
AR108992A1 (es) 2016-07-08 2018-10-17 Ferring Bv Formulaciones líquidas estabilizadas que contienen picosulfato
RS64722B1 (sr) 2017-06-20 2023-11-30 Takeda Pharmaceuticals Co Heterociklično jedinjenje i njegova upotreba kao pozitivnog alosteričkog modulatora holinergičkog muskarinskog m1 receptora
JP2020530448A (ja) 2017-08-09 2020-10-22 アルビレオ・アクチボラグ コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用
AU2019232477A1 (en) 2018-03-09 2020-09-10 Elobix Ab Process for the preparation of elobixibat
US10428109B1 (en) 2018-03-09 2019-10-01 Elobix Ab Process for the preparation of 1,5-benzothiazepine compounds
ES2942443T3 (es) 2018-06-05 2023-06-01 Albireo Ab Compuestos de benzotia(di)azepina y su uso como moduladores de ácidos biliares
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
PE20210136A1 (es) 2018-06-20 2021-01-21 Albireo Ab Formulacion farmaceutica de odevixibat
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
SMT202300020T1 (it) 2019-02-06 2023-03-17 Albireo Ab Composti di benzotiadiazepine e loro uso come modulatori degli acidi biliari
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
EP3923943B1 (en) 2019-02-12 2024-07-31 Mirum Pharmaceuticals, Inc. Genotype and dose-dependent response to an asbti in patients with bile salt export pump deficiency
WO2021049311A1 (ja) 2019-09-09 2021-03-18 エロビクス・アーベー １，５－ベンゾチアゼピン化合物を製造するための方法
ES2972045T3 (es) 2019-12-04 2024-06-10 Albireo Ab Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar
ES2973549T3 (es) 2019-12-04 2024-06-20 Albireo Ab Compuestos de benzoti(di)azepina y su uso como moduladores de los ácidos biliares
JP7665620B2 (ja) 2019-12-04 2025-04-21 アルビレオ・アクチボラグ ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
EP4069361B1 (en) 2019-12-04 2024-01-03 Albireo AB Benzothia(di)azepine compounds and their use as bile acid modulators
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
ES3002777T3 (en) 2020-08-03 2025-03-07 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
KR20230106651A (ko) 2020-11-12 2023-07-13 알비레오 에이비 진행성 가족성 간내 담즙정체증(pfic)을 치료하기 위한 오데빅시바트
CA3198216A1 (en) 2020-12-04 2022-06-09 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途
WO2022166680A1 (zh) * 2021-06-25 2022-08-11 苏州科睿思制药有限公司 奥德昔巴特的晶型及其制备方法和用途
WO2023203248A1 (en) 2022-04-22 2023-10-26 Albireo Ab Subcutaneous administration of an asbt inhibitor

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4771072A (en) 1985-01-10 1988-09-13 Tanabe Seiyaku Co., Ltd. Alkoxynaphthalene derivatives
JPS6310746A (ja) 1986-07-01 1988-01-18 Tanabe Seiyaku Co Ltd ナフタレン誘導体
US4900757A (en) 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
DE3930696A1 (de) 1989-09-14 1991-03-28 Hoechst Ag Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
FI106800B (fi) 1990-12-06 2001-04-12 Hoechst Ag Menetelmä uusien terapeuttisesti käyttökelpoisten dimeeristen sappihappojohdannaisten valmistamiseksi
DE69228262D1 (de) 1991-10-17 1999-03-04 Shionogi & Co Verfahren zum Herstellen von Lignin-Analoga und Ausgangsprodukte dafür
ATE135380T1 (de) 1991-12-20 1996-03-15 Hoechst Ag Polymere und oligomere von gallensäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH05186357A (ja) * 1991-12-31 1993-07-27 Shigeo Ochi 飲食物消化分解産物吸収抑制手段
GB9201180D0 (en) * 1992-01-21 1992-03-11 Glaxo Group Ltd Chemical compounds
GB9203347D0 (en) 1992-02-17 1992-04-01 Wellcome Found Hypolipidaemic compounds
ATE160783T1 (de) 1992-06-12 1997-12-15 Hoechst Ag Gallensäurederivate, verfahren zu ihrer herstellung und verwendung dieser verbindungen als arzneimittel
IL108633A (en) 1993-02-15 1998-07-15 Wellcome Found History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them
IL108634A0 (en) 1993-02-15 1994-05-30 Wellcome Found Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
JP3411036B2 (ja) 1993-04-16 2003-05-26 塩野義製薬株式会社 リグナン系化合物の製造方法
TW289021B (es) 1993-05-08 1996-10-21 Hoechst Ag
TW289020B (es) 1993-05-08 1996-10-21 Hoechst Sktiengesellschaft
EP0624593A3 (de) 1993-05-08 1995-06-07 Hoechst Ag Gallensäurederivate, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen als Arzneimittel.
ZA956647B (en) 1994-08-10 1997-02-10 Wellcome Found Hypolipidaemic compounds.
CN1084741C (zh) 1994-09-13 2002-05-15 孟山都公司 具有回肠胆汁酸转运和牛磺胆酸盐摄入抑制剂作用的新的苯并硫杂䓬
US5994391A (en) 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
GB9423172D0 (en) 1994-11-17 1995-01-04 Wellcom Foundation The Limited Hypolipidemic benzothiazepines
CN1515567A (zh) 1996-03-11 2004-07-28 G.D.ɪ����˾ 具有作为回肠胆汁酸转运和牛磺胆酸盐吸收抑制剂活性的新的苯并噻庚因
WO1998007749A1 (en) 1996-08-23 1998-02-26 Human Genome Sciences, Inc. Novel human growth factors
JPH1072371A (ja) 1996-08-28 1998-03-17 Sankyo Co Ltd 回腸型胆汁酸トランスポーター阻害剤
GB9704208D0 (en) 1997-02-28 1997-04-16 Glaxo Group Ltd Chemical compounds
IL131872A0 (en) 1997-03-11 2001-03-19 Searle & Co Composition comprising an ileal bile acid transport inhibiting benzothiepines and hmg co-a reductase inhibitors
DE69815180T2 (de) 1997-03-14 2004-04-29 Aventis Pharma Deutschland Gmbh Hypolipidemische 1,4-Benzothiazepin-1,1-dioxide
EP0869121B1 (de) 1997-04-04 2004-06-09 Aventis Pharma Deutschland GmbH Hypolipidämische Propanolaminderivate
DE19845402B4 (de) 1998-10-02 2005-04-07 Aventis Pharma Deutschland Gmbh Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
WO1998056757A1 (fr) 1997-06-11 1998-12-17 Sankyo Company, Limited Derives de benzylamine
AUPO763197A0 (en) * 1997-06-30 1997-07-24 Sigma Pharmaceuticals Pty Ltd Health supplement
ES2195428T3 (es) 1997-12-19 2003-12-01 Searle & Co Metodo para preparar oxidos de tetrahidrobenzotiepina enriquecidos enantiometricamente.
GB9800428D0 (en) 1998-01-10 1998-03-04 Glaxo Group Ltd Chemical compounds
DE19825804C2 (de) 1998-06-10 2000-08-24 Aventis Pharma Gmbh 1,4-Benzothiepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19845405C2 (de) 1998-10-02 2000-07-13 Aventis Pharma Gmbh Arylsubstituierte Propanolaminderivate und deren Verwendung
DE19845406C2 (de) 1998-10-02 2001-10-18 Aventis Pharma Gmbh Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19845403B4 (de) 1998-10-02 2005-02-10 Aventis Pharma Deutschland Gmbh Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
WO2000035889A1 (en) 1998-12-11 2000-06-22 Sankyo Company, Limited Substituted benzylamines
AU776620B2 (en) 1998-12-23 2004-09-16 G.D. Searle Llc Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
ATE240120T1 (de) 1998-12-23 2003-05-15 Searle Llc Kombinationen von ileumgallensäuretransports inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
EP1354604A1 (en) 1998-12-23 2003-10-22 G.D. Searle LLC. Combinations for cardiovascular indications
EA004877B1 (ru) 1998-12-23 2004-08-26 Джи.Ди.Сирл Ллс Сочетания ингибиторов транспорта желчных кислот в подвздошной кишке и агентов, секвестрирующих желчные кислоты, для сердечно-сосудистых показаний
ES2188285T3 (es) 1998-12-23 2003-06-16 Searle Llc Combinaciones de inhibidores del transporte de acidos biliares ileales y derivados de acido nicotinico para indicaciones cardiovasculares.
JP2002536440A (ja) 1999-02-12 2002-10-29 ジー．ディー．サール エルエルシー 回腸胆汁酸輸送およびタウロコール酸塩取り込みの阻害剤としての活性を有する新規１，２−ベンゾチアゼピン
DE19916108C1 (de) 1999-04-09 2001-01-11 Aventis Pharma Gmbh Mit Zuckerresten substituierte 1,4-Benzothiazepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
SE9901387D0 (sv) 1999-04-19 1999-04-19 Astra Ab New pharmaceutical foromaulations
US6287609B1 (en) 1999-06-09 2001-09-11 Wisconsin Alumni Research Foundation Unfermented gel fraction from psyllium seed husks
CZ290178B6 (cs) 1999-07-22 2002-06-12 Sankyo Company Limited Deriváty cyklobutenu
WO2001034570A1 (en) 1999-11-08 2001-05-17 Sankyo Company, Limited Nitrogenous heterocycle derivatives
CA2400021A1 (en) 2000-02-18 2001-08-23 Merck & Co., Inc. Aryloxyacetic acids for diabetes and lipid disorders
SE0000772D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab Chemical compounds
AU2001240115A1 (en) 2000-03-10 2001-09-24 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20020061888A1 (en) 2000-03-10 2002-05-23 Keller Bradley T. Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
US20020183307A1 (en) 2000-07-26 2002-12-05 Tremont Samuel J. Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake
SE0003766D0 (sv) 2000-10-18 2000-10-18 Astrazeneca Ab Novel formulation
EG26979A (en) * 2000-12-21 2015-03-01 Astrazeneca Ab Chemical compounds
WO2002053548A1 (fr) 2000-12-27 2002-07-11 Banyu Pharmaceutical Co.,Ltd. Derives de la benzothiazepine
US6506921B1 (en) * 2001-06-29 2003-01-14 Virginia Tech Intellectual Properties, Inc. Amine compounds and curable compositions derived therefrom
GB0121337D0 (en) 2001-09-04 2001-10-24 Astrazeneca Ab Chemical compounds
AR036873A1 (es) * 2001-09-07 2004-10-13 Euro Celtique Sa Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento
GB0121622D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
GB0121621D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
ES2278045T3 (es) * 2001-09-08 2007-08-01 Astrazeneca Ab Derivados benzotiazepinicos y benzotiadiazepinicos con actividad inhibidora del transporte de acidos biliares del ileon (ibat) para el tratamiento de hiperlipidemia.
GB0201850D0 (en) * 2002-01-26 2002-03-13 Astrazeneca Ab Therapeutic treatment
GB0209467D0 (en) 2002-04-25 2002-06-05 Astrazeneca Ab Chemical compounds
GB0213669D0 (en) 2002-06-14 2002-07-24 Astrazeneca Ab Chemical compounds
GB0216321D0 (en) 2002-07-13 2002-08-21 Astrazeneca Ab Therapeutic treatment
GB0304194D0 (en) 2003-02-25 2003-03-26 Astrazeneca Ab Chemical compounds
GB0307918D0 (en) * 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use

Also Published As

Publication number Publication date
SA04250066B1 (ar) 2008-09-22
US7514421B2 (en) 2009-04-07
MXPA05010706A (es) 2005-12-12
NO20054369D0 (no) 2005-09-21
CN1771027A (zh) 2006-05-10
DK1610770T3 (da) 2008-05-13
DE602004012079T2 (de) 2009-02-26
IL170913A (en) 2010-11-30
SI1894564T1 (sl) 2011-08-31
EP1894564A3 (en) 2009-09-09
AU2004228731B2 (en) 2008-02-28
SI1610770T1 (sl) 2008-06-30
RU2482850C2 (ru) 2013-05-27
BRPI0408858A (pt) 2006-04-11
ES2368350T3 (es) 2011-11-16
CY1107424T1 (el) 2012-12-19
RU2005128792A (ru) 2006-05-10
ATE513550T1 (de) 2011-07-15
JP4870552B2 (ja) 2012-02-08
ZA200507996B (en) 2007-04-25
ATE387194T1 (de) 2008-03-15
WO2004089350A1 (en) 2004-10-21
MY137757A (en) 2009-03-31
CN100366241C (zh) 2008-02-06
CA2520109A1 (en) 2004-10-21
NO335140B1 (no) 2014-09-29
CO5640076A2 (es) 2006-05-31
EP1610770A1 (en) 2006-01-04
EP1610770B1 (en) 2008-02-27
PT1894564E (pt) 2011-07-26
EP1894564A2 (en) 2008-03-05
KR20050121241A (ko) 2005-12-26
AU2004228731A1 (en) 2004-10-21
PL1894564T3 (pl) 2011-11-30
ES2299832T3 (es) 2008-06-01
UA84141C2 (ru) 2008-09-25
CY1111995T1 (el) 2015-11-04
TWI338577B (en) 2011-03-11
RU2008129204A (ru) 2010-01-27
RU2342928C2 (ru) 2009-01-10
PL1610770T3 (pl) 2008-07-31
NZ542835A (en) 2009-01-31
CA2520109C (en) 2012-03-20
DE602004012079D1 (de) 2008-04-10
JP5421326B2 (ja) 2014-02-19
HK1085666A1 (en) 2006-09-01
TW200505434A (en) 2005-02-16
EP1894564B1 (en) 2011-06-22
GB0307918D0 (en) 2003-05-14
AR043985A1 (es) 2005-08-17
PT1610770E (pt) 2008-04-10
KR101321577B1 (ko) 2013-10-25
JP2011173925A (ja) 2011-09-08
JP2006522082A (ja) 2006-09-28
NO20054369L (no) 2005-11-15
US20060199797A1 (en) 2006-09-07
DK1894564T3 (da) 2011-08-29
IS8113A (is) 2005-11-01

Similar Documents

Publication Publication Date Title
UY28258A1 (es) Tratamiento terapeutico
ATE461217T1 (de) Glp-1-verbindungen
ES2319886T3 (es) Compuestos azabiciclicos condensados que inhiben el sutipo 1 del receptor valinoide (vr1).
NO20055253L (no) Behandling av autoimmun sykdom i en pasient med utilstrekkelig respons pa en TNF-alfa-inhibitor
CL2007002384A1 (es) Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento de la psoriasis.
NI200700111A (es) Uso de un inhibidor de mtor en el tratamiento del leiomioma del útero
CR7993A (es) Combinaciones antineoplasicas
BR0209645A (pt) Oxazolo- e furopirimidinas e seu uso como medicamentos
SE0301650D0 (sv) Novel compounds
DE60122559D1 (de) Indolderivate als pde5-inhibitoren
TR200302134T4 (tr) 2-metil-tiazolidin-2,4-dikarboksilik asit ve/veya bunun fizyolojik olarak uygun tuzlarının anti-kanser ajanları olarak kullanımı.
MXPA02012911A (es) Compuestos de rutenio (ii) para el uso en terapia del cancer.
HRP20090513T1 (hr) S-mirtazapin, namijenjen liječenju napadaja vrućine
UY26648A1 (es) Inhibidores de vasopeptidasa para tratar hipertensión sistólica aislada
ATE399532T1 (de) Medizinische seife
DE50309647D1 (de) Ng fibrotischer erkrankungen
GT200400224A (es) Metodo de tratamiento del linfoma de celulas del manto
NO20071330L (no) Enzyminhibitor i leukemi
EA200600573A1 (ru) Активаторы плазминогена, имеющие сниженную способность связывать лизин
ATE491457T1 (de) Kombinationstherapie gegen tumoren mit substituierten acryloyl-distamycin-derivaten, taxanen und/oder antimetaboliten
CY1111319T1 (el) Ενωση 4-μεθυλεξανοϊκης κααλαλιδης f
ATE348803T1 (de) Tryptase-inhibitoren
BR0214848A (pt) Tratamento de glioblastoma com timosina alfa-1
ATE364037T1 (de) Tryptasehemmer
ATE358488T1 (de) Behandlung von dyskinesie mit 2,3-benzodiazepinen

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160621