UY27346A1 - Composiciones farmaccuticas que contienen conjuntos de polemero y frrmaco. - Google Patents
Composiciones farmaccuticas que contienen conjuntos de polemero y frrmaco.Info
- Publication number
- UY27346A1 UY27346A1 UY27346A UY27346A UY27346A1 UY 27346 A1 UY27346 A1 UY 27346A1 UY 27346 A UY27346 A UY 27346A UY 27346 A UY27346 A UY 27346A UY 27346 A1 UY27346 A1 UY 27346A1
- Authority
- UY
- Uruguay
- Prior art keywords
- pharmaccutic
- frrmaco
- sets
- containing polymer
- compositions containing
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 230000000712 assembly Effects 0.000 abstract 2
- 238000000429 assembly Methods 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Se describen soluciones que contienen conjuntos de polímero/fármaco de un fármaco de baja solubilidad y un polímero. Además, se describen dichos conjuntos de polímero/fármaco agregados sólidos que comprenden un fármaco de baja solubilidad y polímero.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30025901P | 2001-06-22 | 2001-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY27346A1 true UY27346A1 (es) | 2003-01-31 |
Family
ID=23158343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY27346A UY27346A1 (es) | 2001-06-22 | 2002-06-21 | Composiciones farmaccuticas que contienen conjuntos de polemero y frrmaco. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20030170309A1 (es) |
| EP (1) | EP1401399A2 (es) |
| JP (1) | JP2004534811A (es) |
| AP (1) | AP2002002558A0 (es) |
| AU (1) | AU2002309172A1 (es) |
| BR (1) | BR0211028A (es) |
| CA (1) | CA2450748A1 (es) |
| GT (1) | GT200200125A (es) |
| HN (1) | HN2002000152A (es) |
| MX (1) | MXPA03011935A (es) |
| PA (1) | PA8548801A1 (es) |
| PE (1) | PE20030192A1 (es) |
| SV (1) | SV2003001106A (es) |
| UY (1) | UY27346A1 (es) |
| WO (1) | WO2003000226A2 (es) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7115279B2 (en) * | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
| EE200400024A (et) * | 2001-06-21 | 2004-06-15 | Pfizer Products Inc. | Kolesterüülestri ülekandevalgu inhibiitorite iseemulgeeruvad formulatsioonid |
| AU2002334987A1 (en) * | 2001-10-15 | 2003-04-28 | The Regents Of The University Of Michigan | Systems and methods for the generation of crystalline polymorphs |
| WO2003063822A2 (en) | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus |
| ES2305434T3 (es) | 2002-02-01 | 2008-11-01 | Pfizer Products Inc. | Composiciones framaceuticas de dispersiones amorfas de farmacos y materiales que forman microfases lipofilas. |
| CN1681479A (zh) * | 2002-08-12 | 2005-10-12 | 辉瑞产品公司 | 半有序药物和聚合物的药物组合物 |
| US7838029B1 (en) | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| KR20050104152A (ko) | 2004-04-28 | 2005-11-02 | 최승호 | 경구용 약물의 흡수를 증진하는 약제학적 조성물 |
| CN101123951A (zh) * | 2004-08-31 | 2008-02-13 | 辉瑞产品公司 | 包括低溶解性药物和聚合物的药物剂型 |
| ZA200704767B (en) * | 2004-11-05 | 2008-08-27 | King Pharmaceuticals Res & Dev | Stabilized individually coated ramipril particles, compositions and methods |
| WO2006069162A1 (en) * | 2004-12-20 | 2006-06-29 | Reddy Us Therapeutics, Inc. | Novel heterocyclic compounds and their pharmaceutical compositions |
| US8604055B2 (en) * | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| US9040558B2 (en) | 2004-12-31 | 2015-05-26 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| EP1690528A1 (de) * | 2005-02-11 | 2006-08-16 | Abbott GmbH & Co. KG | Herstellung von Dosierungsformen mit einer festen Dispersion eines mikrokristallinen Wirkstoffs |
| CN101277682B (zh) * | 2005-07-28 | 2015-07-29 | Isp投资有限公司 | 无定形依发韦仑及其生产 |
| CA2621800A1 (en) * | 2005-09-06 | 2007-03-15 | Astellas Pharma Inc. | Fine particles of poorly soluble drug having enteric base material adsorbed on the surface thereof |
| US7811604B1 (en) | 2005-11-14 | 2010-10-12 | Barr Laboratories, Inc. | Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same |
| US20080085315A1 (en) * | 2006-10-10 | 2008-04-10 | John Alfred Doney | Amorphous ezetimibe and the production thereof |
| WO2008065506A2 (en) * | 2006-11-29 | 2008-06-05 | Pfizer Products Inc. | Pharmaceutical compositions comprising nanoparticles comprising enteric polymers and casein |
| US8613946B2 (en) * | 2006-12-21 | 2013-12-24 | Isp Investment Inc. | Carotenoids of enhanced bioavailability |
| EP2125938A2 (en) * | 2007-01-26 | 2009-12-02 | Isp Investments Inc. | Formulation process method to produce spray dried products |
| CA2676670C (en) | 2007-02-02 | 2012-03-13 | Pfizer Products Inc. | Tricyclic compounds, compositions, and methods |
| JP5828616B2 (ja) * | 2007-03-30 | 2015-12-09 | 味の素株式会社 | 固体分散体製剤 |
| JP5328643B2 (ja) * | 2007-04-20 | 2013-10-30 | 大同化成工業株式会社 | 新規乾式固体分散体用基剤、該基剤を含有する固体分散体及び該分散体を含有する組成物 |
| WO2008135855A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
| WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
| EP2162120B1 (en) | 2007-06-04 | 2016-05-04 | Bend Research, Inc | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
| US9545384B2 (en) | 2007-06-04 | 2017-01-17 | Bend Research, Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate |
| WO2009073215A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
| EP2240162A4 (en) | 2007-12-06 | 2013-10-09 | Bend Res Inc | NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER |
| US20110002989A1 (en) * | 2008-03-07 | 2011-01-06 | Pfizer Inc. | Methods, dosage forms and kits for administering ziprasidone without food |
| IL192262A (en) * | 2008-06-17 | 2016-05-31 | Z H T Eng Equipment And Tech Ltd | A polymer that releases drugs into the animal body, a medicinal product containing it and a method for its preparation |
| EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
| US20130108701A1 (en) | 2010-05-25 | 2013-05-02 | Krishna Murthy Bhavanasi | Solid Dosage Forms of Antipsychotics |
| TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠(olopatadine)眼用組成物 |
| US9199967B2 (en) | 2011-08-18 | 2015-12-01 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (CETP) inhibitors |
| IN2014CN02290A (es) | 2011-09-27 | 2015-06-19 | Reddys Lab Ltd Dr | |
| US10076496B2 (en) * | 2011-11-11 | 2018-09-18 | The Chinese University Of Hong Kong | Engineering of polymer-stabilized nanoparticles for drugs with Log P values below 6 by controlled antisolvent precipitation |
| US9211290B2 (en) * | 2012-12-31 | 2015-12-15 | Noven Therapeutics, Llc | Solid dispersions of amorphous paroxetine mesylate |
| CA2935307C (en) | 2013-12-31 | 2023-05-09 | Ascendia Pharmaceuticals, Llc | Pharmaceutical compositions for poorly water-soluble compounds |
| US20180185399A1 (en) * | 2015-07-03 | 2018-07-05 | Zhejiang Hisun Pharmaceutical Co., Ltd. | Ginsenoside c-k oral solid preparation and preparation method thereof |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4127647A (en) * | 1975-04-08 | 1978-11-28 | Meiji Seika Kaisha, Ltd. | Process for preparation of stable amorphous macrolide antibiotic solids |
| US4344934A (en) * | 1978-11-20 | 1982-08-17 | American Home Products Corporation | Therapeutic compositions with enhanced bioavailability |
| DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
| FR2525108B1 (fr) * | 1982-04-19 | 1989-05-12 | Elan Corp Ltd | Medicaments a haut degre de solubilite et procede pour leur obtention |
| US4826689A (en) * | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
| IT1187751B (it) * | 1985-10-15 | 1987-12-23 | Eurand Spa | Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute |
| IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
| FR2608988B1 (fr) * | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
| ES2043766T3 (es) * | 1987-11-11 | 1994-01-01 | Pharmascience Lab | Una nueva composicion farmaceutica que comprende exifona y un polimero soluble en agua. |
| JP2528706B2 (ja) * | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
| US5368864A (en) * | 1988-11-25 | 1994-11-29 | Henning Berlin Gmbh Chemie- Und Pharmawerk | Formulation of oxypurinol and/or its alkali and alkaline earth salts |
| DK546289D0 (da) * | 1989-11-02 | 1989-11-02 | Danochemo As | Carotenoidpulvere |
| IE67187B1 (en) * | 1990-06-15 | 1996-03-06 | Merck & Co Inc | A crystallization method to improve crystal structure and size |
| AU641267B2 (en) * | 1990-07-19 | 1993-09-16 | Otsuka Pharmaceutical Co., Ltd. | Solid preparation |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| JP2527107B2 (ja) * | 1991-04-16 | 1996-08-21 | 日本新薬株式会社 | 固体分散体の製造方法 |
| ES2034891B1 (es) * | 1991-08-08 | 1993-12-16 | Cusi Lab | Procedimiento de elaboracion en continuo de sistemas coloidales dispersos, en forma de nanocapsulas o nanoparticulas. |
| US5340591A (en) * | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
| IT1255792B (it) * | 1992-08-05 | 1995-11-16 | Bayer Italia Spa | Composizioni farmaceutiche per la somministrazione orale di diidropiridine in forma di bevanda |
| DE4244466C2 (de) * | 1992-12-24 | 1995-02-23 | Pharmatech Gmbh | Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten |
| US5885486A (en) * | 1993-03-05 | 1999-03-23 | Pharmaciaand Upjohn Ab | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
| DE4316537A1 (de) * | 1993-05-18 | 1994-11-24 | Basf Ag | Zubereitungen in Form fester Lösungen |
| FR2721510B1 (fr) * | 1994-06-22 | 1996-07-26 | Rhone Poulenc Rorer Sa | Nanoparticules filtrables dans des conditions stériles. |
| FR2722984B1 (fr) * | 1994-07-26 | 1996-10-18 | Effik Lab | Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees |
| SE9403846D0 (sv) * | 1994-11-09 | 1994-11-09 | Univ Ohio State Res Found | Small particle formation |
| US5716642A (en) * | 1995-01-10 | 1998-02-10 | Nano Systems L.L.C. | Microprecipitation of nanoparticulate pharmaceutical agents using surface active material derived from similar pharmaceutical agents |
| US5665331A (en) * | 1995-01-10 | 1997-09-09 | Nanosystems L.L.C. | Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers |
| US5560932A (en) * | 1995-01-10 | 1996-10-01 | Nano Systems L.L.C. | Microprecipitation of nanoparticulate pharmaceutical agents |
| US5662883A (en) * | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5510118A (en) * | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
| US20040018236A1 (en) * | 1995-05-08 | 2004-01-29 | Robert Gurny | Nanoparticles for oral administration of pharmaceutical agents of low solubility |
| US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| DE19531684A1 (de) * | 1995-08-29 | 1997-03-06 | Bayer Ag | Verfahren zur Herstellung von Arzneimittelzubereitungen mit kontrollierter Freisetzung |
| WO1997014407A1 (en) * | 1995-10-17 | 1997-04-24 | Research Triangle Pharmaceuticals | Insoluble drug delivery |
| FR2742357B1 (fr) * | 1995-12-19 | 1998-01-09 | Rhone Poulenc Rorer Sa | Nanoparticules stabilisees et filtrables dans des conditions steriles |
| DE19637517A1 (de) * | 1996-09-13 | 1998-03-19 | Basf Ag | Herstellung von pulverförmigen, kaltwasserdispergierbaren Carotinoid-Zubereitungen und die Verwendung der neuen Carotinoid-Zubereitungen |
| US6045829A (en) * | 1997-02-13 | 2000-04-04 | Elan Pharma International Limited | Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers |
| US5955475A (en) * | 1997-06-30 | 1999-09-21 | Endo Pharmaceuticals Inc. | Process for manufacturing paroxetine solid dispersions |
| ATE364374T1 (de) * | 1997-08-11 | 2007-07-15 | Pfizer Prod Inc | Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit |
| US6027747A (en) * | 1997-11-11 | 2000-02-22 | Terracol; Didier | Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions |
| US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
| US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
| US6428814B1 (en) * | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
| ES2307482T3 (es) * | 1999-02-10 | 2008-12-01 | Pfizer Products Inc. | Dispersiones farmaceuticas solidas. |
| US6706283B1 (en) * | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
| EP1027887B1 (en) * | 1999-02-10 | 2008-08-13 | Pfizer Products Inc. | Matrix controlled release device |
| DE19918434A1 (de) * | 1999-04-23 | 2000-10-26 | Basf Ag | Feste Pharmazeutische Formulierungen von säurelabilen Protonenpumpenblockern |
| PT1239831E (pt) * | 1999-12-23 | 2013-01-23 | Mayne Pharma International Pty Ltd | Composições farmacêuticas melhoradas para fármacos fracamente solúveis |
| EA004370B1 (ru) * | 1999-12-23 | 2004-04-29 | Пфайзер Продактс Инк. | Лекарственная форма с высвобождением лекарства под действием гидрогеля |
| CZ20022047A3 (cs) * | 1999-12-23 | 2003-09-17 | Pfizer Products Inc. | Farmaceutické kompozice poskytující zvýšenou koncentraci léčiva |
| BR0016707A (pt) * | 1999-12-23 | 2002-09-03 | Pfizer Prod Inc | Forma de dosagem de droga em camadas acionada por hidrogel |
| US20040009229A1 (en) * | 2000-01-05 | 2004-01-15 | Unger Evan Charles | Stabilized nanoparticle formulations of camptotheca derivatives |
| CA2400172C (en) * | 2000-02-28 | 2010-04-20 | Genesegues, Inc. | Nanocapsule encapsulation system and method |
| AR027656A1 (es) * | 2000-03-16 | 2003-04-09 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la glucogeno-fosforilasa |
| US20010053791A1 (en) * | 2000-03-16 | 2001-12-20 | Babcock Walter C. | Glycogen phosphorylase inhibitor |
| US6623765B1 (en) * | 2000-08-01 | 2003-09-23 | University Of Florida, Research Foundation, Incorporated | Microemulsion and micelle systems for solubilizing drugs |
| US7115279B2 (en) * | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
| US8551526B2 (en) * | 2000-11-03 | 2013-10-08 | Board Of Regents, The University Of Texas System | Preparation of drug particles using evaporation precipitation into aqueous solutions |
| US6756062B2 (en) * | 2000-11-03 | 2004-06-29 | Board Of Regents University Of Texas System | Preparation of drug particles using evaporation precipitation into aqueous solutions |
| US6951656B2 (en) * | 2000-12-22 | 2005-10-04 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6607784B2 (en) * | 2000-12-22 | 2003-08-19 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US8067032B2 (en) * | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| FR2820320B1 (fr) * | 2001-02-02 | 2003-04-04 | Oreal | Suspension de nanospheres de principe actif lipophile stabilisee par des polymeres hydrodispersibles |
| US8137699B2 (en) * | 2002-03-29 | 2012-03-20 | Trustees Of Princeton University | Process and apparatuses for preparing nanoparticle compositions with amphiphilic copolymers and their use |
| SG126676A1 (en) * | 2001-05-09 | 2007-01-30 | Nanomaterials Tech Pte Ltd | Process for the controlled production of organic particles |
| DE10124952A1 (de) * | 2001-05-21 | 2002-12-12 | Bayer Ag | Verfahren zur Herstellung von Nanodispersionen |
| WO2003000294A1 (en) * | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions containing a solid dispersion of a poorly-soluble drug in a matrix and a solubility-enhancing polymer |
| CA2456806C (en) * | 2001-08-08 | 2011-10-18 | Brown University Research Foundation | Methods for micronization of hydrophobic drugs |
| US20030049323A1 (en) * | 2001-08-29 | 2003-03-13 | Hitt James E. | Process to precipitate drug particles |
| ES2280582T3 (es) * | 2001-09-19 | 2007-09-16 | Elan Pharma International Limited | Formulaciones de insulina en nanoparticulas. |
| US6878693B2 (en) * | 2001-09-28 | 2005-04-12 | Solubest Ltd. | Hydrophilic complexes of lipophilic materials and an apparatus and method for their production |
| EP1458361A4 (en) * | 2001-11-20 | 2007-04-25 | Advanced Inhalation Res Inc | COMPOSITIONS FOR DISTRIBUTING PRODUCTS WITH LASTING EFFECT |
| AU2002360549A1 (en) * | 2001-12-10 | 2003-06-23 | Spherics, Inc. | Methods and products useful in the formation and isolation of microparticles |
| WO2003063822A2 (en) * | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus |
| US7455858B2 (en) * | 2002-05-16 | 2008-11-25 | Qlt Inc. | Compositions and methods for delivery of photosensitive drugs |
| EP1569620A4 (en) * | 2002-10-30 | 2006-03-22 | Spherics Inc | NANOPARTICULAR BIOACTIVE AGENTS |
| KR20050088190A (ko) * | 2002-12-20 | 2005-09-02 | 화이자 프로덕츠 인코포레이티드 | 콜레스테릴 에스터 전달 단백질 억제제 및 hmg-coa환원 효소 억제제를 포함하는 투약 형태 |
| US20040247624A1 (en) * | 2003-06-05 | 2004-12-09 | Unger Evan Charles | Methods of making pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
| JP2007513937A (ja) * | 2003-12-09 | 2007-05-31 | ファイザー インコーポレイテッド | Hivプロテアーゼ阻害剤を含む組成物 |
-
2002
- 2002-06-17 WO PCT/IB2002/002256 patent/WO2003000226A2/en not_active Ceased
- 2002-06-17 JP JP2003506873A patent/JP2004534811A/ja active Pending
- 2002-06-17 MX MXPA03011935A patent/MXPA03011935A/es not_active Application Discontinuation
- 2002-06-17 AU AU2002309172A patent/AU2002309172A1/en not_active Abandoned
- 2002-06-17 EP EP02735849A patent/EP1401399A2/en not_active Ceased
- 2002-06-17 BR BR0211028-8A patent/BR0211028A/pt not_active IP Right Cessation
- 2002-06-17 US US10/173,945 patent/US20030170309A1/en not_active Abandoned
- 2002-06-17 CA CA002450748A patent/CA2450748A1/en not_active Abandoned
- 2002-06-20 PE PE2002000535A patent/PE20030192A1/es not_active Application Discontinuation
- 2002-06-20 AP APAP/P/2002/002558A patent/AP2002002558A0/en unknown
- 2002-06-20 GT GT200200125A patent/GT200200125A/es unknown
- 2002-06-20 HN HN2002000152A patent/HN2002000152A/es unknown
- 2002-06-21 UY UY27346A patent/UY27346A1/es not_active Application Discontinuation
- 2002-06-21 SV SV2002001106A patent/SV2003001106A/es not_active Application Discontinuation
- 2002-06-21 PA PA20028548801A patent/PA8548801A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2450748A1 (en) | 2003-01-03 |
| WO2003000226A3 (en) | 2003-10-23 |
| HN2002000152A (es) | 2003-06-07 |
| AP2002002558A0 (en) | 2002-06-30 |
| WO2003000226A2 (en) | 2003-01-03 |
| BR0211028A (pt) | 2004-06-15 |
| EP1401399A2 (en) | 2004-03-31 |
| MXPA03011935A (es) | 2004-03-26 |
| PE20030192A1 (es) | 2003-03-12 |
| JP2004534811A (ja) | 2004-11-18 |
| SV2003001106A (es) | 2003-03-18 |
| AU2002309172A1 (en) | 2003-01-08 |
| PA8548801A1 (es) | 2003-09-17 |
| GT200200125A (es) | 2003-05-15 |
| US20030170309A1 (en) | 2003-09-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY27346A1 (es) | Composiciones farmaccuticas que contienen conjuntos de polemero y frrmaco. | |
| CR7171A (es) | Composiciones farmaceuticas de farmacos y polimeros acidos neutralizados | |
| BR0215405A (pt) | Composições e processos de uso de collajolie | |
| PA8513601A1 (es) | Composiciones farmaceuticas de inhibidores de la glucogenofosforilasa | |
| UY27381A1 (es) | 2-tio-3,5-diciano-4-fenil-6-aminopiridinas sustituidas y su uso | |
| GT200100039A (es) | Inhibidor de la glucogeno fosforilasa. | |
| HN2001000244A (es) | Inhibidores de espiropirimidin - 2, 4, 6 - triona metaloproteinasas. | |
| HRP20030383B1 (hr) | Laktamski spoj | |
| PE20020108A1 (es) | Estructuras y composiciones que aumentan la estabilidad de activos de peroxido | |
| DE60111933D1 (de) | Gel zusammensetzungen | |
| CR8824A (es) | Derivados de 2-carbamida-4-feniltiazol, su preparacion y su aplicacion en terapeutica | |
| BR0116166A (pt) | Inibidores da serina protease | |
| SE9901077D0 (sv) | Novel use | |
| NO20015892D0 (no) | Inhibitorer av metallproteinaser | |
| DK1204659T3 (da) | Serotonerge benzofuraner | |
| DE50205129D1 (de) | 8-tetradecenal als duft- oder aromastoff | |
| PT1244643E (pt) | Inibidores da triptase | |
| HRP20050611B1 (hr) | Kombinacijski lijek | |
| DK1244614T3 (da) | Tryptase-inhibitorer | |
| ATE388723T1 (de) | Zusammensetzung enthaltend epigallocatechin- gallat | |
| DOP2002000421A (es) | Composiciones farmaceuticas que contienen conjunto de pollimero y farmaco. | |
| PT1299114E (pt) | Composicao farmaceutica de diclofenac com base em vitamina e, papina e hialuronidase | |
| BR9901387A (pt) | Composições para a cura de polìmero. | |
| ATE364037T1 (de) | Tryptasehemmer | |
| ATE263764T1 (de) | Trioxepan verbindungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20141203 |