[go: up one dir, main page]

UY27413A1 - Agonistas de la oxitocina - Google Patents

Agonistas de la oxitocina

Info

Publication number
UY27413A1
UY27413A1 UY27413A UY27413A UY27413A1 UY 27413 A1 UY27413 A1 UY 27413A1 UY 27413 A UY27413 A UY 27413A UY 27413 A UY27413 A UY 27413A UY 27413 A1 UY27413 A1 UY 27413A1
Authority
UY
Uruguay
Prior art keywords
agonists
oxychocine
compounds
ositocin
nr5r6
Prior art date
Application number
UY27413A
Other languages
English (en)
Inventor
Gary Robert William Pitt
David Philip Rooker
Andrzej Roman Batt
Celine Marguerite Simo Laurent
Michael Bryan Roe
Peter Jeremy Hudson
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of UY27413A1 publication Critical patent/UY27413A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Los compuestos de acuerdo con la fórmula general 1, donde G1 es NR5R6 o un grupo policíclico fusionado con novedosos. Son agonistas selectivos y potentes de la ositocina. Las composiciones farmacéuticas de tales compuestos son útiles en el tratamiento de, por ejemplo, la disfunción eréctil.
UY27413A 2001-08-16 2002-08-12 Agonistas de la oxitocina UY27413A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0120051.8A GB0120051D0 (en) 2001-08-16 2001-08-16 Oxytocin agonists

Publications (1)

Publication Number Publication Date
UY27413A1 true UY27413A1 (es) 2003-02-28

Family

ID=9920554

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27413A UY27413A1 (es) 2001-08-16 2002-08-12 Agonistas de la oxitocina

Country Status (17)

Country Link
US (1) US20050032777A1 (es)
EP (1) EP1421087A1 (es)
JP (1) JP2005501858A (es)
KR (1) KR20040023728A (es)
CN (1) CN1285594C (es)
AR (1) AR042591A1 (es)
CA (1) CA2453962A1 (es)
GB (1) GB0120051D0 (es)
IL (1) IL159821A0 (es)
MX (1) MXPA04001447A (es)
NO (1) NO20041819L (es)
NZ (1) NZ530587A (es)
PL (1) PL367543A1 (es)
RU (2) RU2311417C2 (es)
UY (1) UY27413A1 (es)
WO (1) WO2003016316A1 (es)
ZA (1) ZA200400272B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000079D0 (en) 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
EP1449844A1 (en) * 2003-02-14 2004-08-25 Ferring B.V. benzamide derivatives as oxytocin agonists and vasopressin antagonists
KR20060065586A (ko) * 2003-06-23 2006-06-14 씨브이 쎄러퓨틱스, 인코포레이티드 지방산 산화 저해제로서의, 피페라진 및 피페리딘의 우레아유도체
EP1512687A1 (en) * 2003-09-05 2005-03-09 Ferring B.V. Piperazines as oxytocin agonists
EP1632494A1 (en) 2004-08-24 2006-03-08 Ferring B.V. Vasopressin v1a antagonists
RU2008114374A (ru) * 2005-10-24 2009-12-10 Вайет (Us) Трициклические соединения, применяемые в качестве агонистов рецептора окситоцина
GB0903493D0 (en) 2009-02-27 2009-04-08 Vantia Ltd New compounds
GB201004677D0 (en) 2010-03-19 2010-05-05 Vantia Ltd New salt
US9101569B2 (en) 2010-05-18 2015-08-11 Universite De Geneve Methods for the treatment of insulin resistance
WO2011147889A1 (en) 2010-05-25 2011-12-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical composition for the treatment of a feeding disorder with early-onset in a patient
CN103159641A (zh) * 2011-12-14 2013-06-19 天津泰普药品科技发展有限公司 托伐普坦中间体2-甲酸-5-(2-甲基苯甲酰氨基)甲苯的制备方法
PT3551631T (pt) * 2016-12-12 2024-12-10 Kinoxis Therapeutics Pty Ltd Agonistas de recetor de oxitocina não-peptídicos
CN113429379A (zh) * 2021-06-28 2021-09-24 江苏法安德医药科技有限公司 一种lh-1801中间体及其制备方法和应用
CN116120261B (zh) * 2022-11-30 2024-01-23 浙大宁波理工学院 一种3-[（4-磺胺哌嗪-1-基）甲基]苯甲酸类化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2116334A1 (en) * 1992-07-02 1994-01-20 Hidenori Ogawa Oxytocin antagonist
AR011913A1 (es) * 1997-03-06 2000-09-13 Yamano Masaki Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos.
JPH111456A (ja) * 1997-06-13 1999-01-06 Otsuka Pharmaceut Co Ltd アミド誘導体
GB2326639A (en) * 1997-06-18 1998-12-30 Merck & Co Inc Piperazine Oxytocin Receptor Antagonists
US5968938A (en) * 1997-06-18 1999-10-19 Merck & Co., Inc. Piperazine oxytocin receptor antagonists

Also Published As

Publication number Publication date
KR20040023728A (ko) 2004-03-18
WO2003016316A1 (en) 2003-02-27
AR042591A1 (es) 2005-06-29
GB0120051D0 (en) 2001-10-10
EP1421087A1 (en) 2004-05-26
WO2003016316A8 (en) 2003-10-02
PL367543A1 (en) 2005-02-21
RU2004101060A (ru) 2005-06-27
CN1543467A (zh) 2004-11-03
RU2007121219A (ru) 2008-12-20
CA2453962A1 (en) 2003-02-27
ZA200400272B (en) 2004-11-18
IL159821A0 (en) 2004-06-20
CN1285594C (zh) 2006-11-22
JP2005501858A (ja) 2005-01-20
RU2311417C2 (ru) 2007-11-27
NO20041819L (no) 2004-05-14
HK1071132A1 (en) 2005-07-08
MXPA04001447A (es) 2004-07-08
US20050032777A1 (en) 2005-02-10
NZ530587A (en) 2004-12-24

Similar Documents

Publication Publication Date Title
ATE291021T1 (de) Oxytocin agonisten
UY27413A1 (es) Agonistas de la oxitocina
ES2190440T3 (es) Compuestos antitumorales, composiciones farmaceuticas, modos de preparacion y para el tratamiento.
CY1107747T1 (el) Υποκατεστημενα τετρακυκλικα παραγωγα πυρρολοκινολονης χρησιμα ως αναστολεις της φωσφοδιεστερασης
PA8503301A1 (es) Compuestos para el tratamiento de la isquemia
UY28150A1 (es) Agentes terapeuticos
PA8465901A1 (es) Nuevos derivados de la eritromicina
ATE337316T1 (de) Imidazo 1,2-aöpyridin-derivate zur prophylaxe und behandlung von herpes-infektionen
ECSP045073A (es) Nuevos derivados de piperazina
ES2188604T3 (es) Inhibidores de proteasa del vih en combinaciones farmaceuticas para eltratamiento del sida.
CY1109808T1 (el) Αρυλινδενο-πυριδινες και αρυλινδενο-πυριμιδινες και η χρηση τους ως ανταγωνιστων των υποδοχεων αδενοσινης α2α
EA200600694A1 (ru) Дисульфидные, сульфидные, сульфоксидные и сульфоновые производные циклических сахаров и их применение
UY27203A1 (es) Bencimidazoles útiles en el tratamiento de la disfunción sexual
UY27410A1 (es) Formas novedosas crudas cristalinas
GT200100251A (es) Procedimiento para la preparacion de imidazotriazinonas substituidas con sulfonamida
AR044275A1 (es) Uso de derivados de sulfonamidas para la fabricacion de un medicamento para la profilaxis y/o tratamiento de las disfunciones alimentarias
ES2183500T3 (es) Nuevos compuestos y composiciones farmaceuticas que los contienen.
AR032341A1 (es) N-(2-metansulfonil-etil)-n-hidroxiformamidas, su uso en la produccion de medicamentos, composiciones farmaceuticas que las contienen, procedimiento para preparar dichos compuestos e intermediarios para su preparacion
SE0100296D0 (sv) New compounds
SE0100295D0 (sv) New compounds
SE0303451D0 (sv) New compounds
SE9902147D0 (sv) Nya föreningar och farmaceutiska kompositioner innehållande desamma
ECSP993209A (es) Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores
ES2086395T3 (es) Fosfolipidos para el tratamiento de esclerosis multiple.
UY27235A1 (es) Compuestos de dihidropirimidina ciano sustituidos y su uso para tratar padecimientos

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20150212