US20040231909A1 - Motorized vehicle having forward and backward differential structure - Google Patents
Motorized vehicle having forward and backward differential structure Download PDFInfo
- Publication number
- US20040231909A1 US20040231909A1 US10/440,861 US44086103A US2004231909A1 US 20040231909 A1 US20040231909 A1 US 20040231909A1 US 44086103 A US44086103 A US 44086103A US 2004231909 A1 US2004231909 A1 US 2004231909A1
- Authority
- US
- United States
- Prior art keywords
- motorized vehicle
- propeller shaft
- thrust bearings
- direction thrust
- bearing seat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Definitions
- the present invention relates to a motorized vehicle, and more particularly to a motorized vehicle having a forward and backward differential structure.
- a conventional motorized vehicle comprises a differential mounted on the transmission gear of the gear box.
- the differential consists of a bevel gear set.
- the power of the motor is reduced by the reduction mechanism.
- the reduced power is transmitted by the transmission gear of the gear box and the bevel gear of the differential to the propeller shafts at the left and right sides, to drive and rotate the wheels at the left and right sides.
- the motorized vehicle is turned, the turning diameter of the wheel at the inner side is shorter than that of the wheel at the outer side, so that the differential consisting of the bevel gear set is used to balance the difference of the rotation speed between the wheel at the inner side and the wheel at the outer side.
- the primary objective of the present invention is to provide a motorized vehicle having a forward and backward differential structure.
- Another objective of the present invention is to provide a motorized vehicle, wherein when the two rear wheels are subjected to a drag or resistance and cannot be rotated with the propeller shaft synchronously, the single-direction thrust bearing will idle, thereby producing a differential effect.
- a further objective of the present invention is to provide a motorized vehicle, wherein the single-direction thrust bearings located at one of the two rear wheels is used to drive the motorized vehicle to move forward, and the single-direction thrust bearings located between the other rear wheel is used to drive the motorized vehicle to move backward.
- a further objective of the present invention is to provide a motorized vehicle having a differential structure which can replace the conventional differential consisting of a bevel gear set, thereby reducing costs of fabrication, and thereby simplifying the construction.
- a motorized vehicle comprising:
- a propeller shaft mounted on the two rear wheels and having two ends;
- the single-direction thrust bearings located between one of the two rear wheels and a first end of the propeller shaft has a rotation direction opposite to a normal rotation direction of the propeller shaft to drive the motorized vehicle to move forward;
- the single-direction thrust bearings located between the other one of the two rear wheels and a second end of the propeller shaft has a rotation direction opposite to a reverse rotation direction of the propeller shaft to drive the motorized vehicle to move backward.
- FIG. 1 is a partially exploded perspective view of a motorized vehicle in accordance with the preferred embodiment of the present invention
- FIG. 2 is a front plan cross-sectional assembly view of the motorized vehicle as shown in FIG. 1;
- FIG. 3 is a top plan cross-sectional assembly view of the motorized vehicle as shown in FIG. 1;
- FIG. 4 is a perspective assembly view of the differential structure of the motorized vehicle in accordance with the preferred embodiment of the present invention.
- FIG. 5 is an exploded perspective view of the differential structure of the motorized vehicle in accordance with the preferred embodiment of the present invention.
- FIG. 6 is a side plan cross-sectional view of the differential structure of the motorized vehicle as shown in FIG. 4;
- FIG. 7 is a schematic top plan operational view showing the turning state of the motorized vehicle in accordance with the preferred embodiment of the present invention.
- FIG. 8 is a side plan cross-sectional assembly view showing the normal transmission state of the motorized vehicle in accordance with the preferred embodiment of the present invention.
- FIG. 9 is a side plan cross-sectional assembly view showing the differential state of the motorized vehicle in accordance with the preferred embodiment of the present invention.
- a motorized vehicle 10 having a forward and backward differential structure in accordance with the preferred embodiment of the present invention has a rear portion provided with a propeller shaft 11 having two ends each provided with a catch flange 12 , a keyway 13 (see FIG. 6), and an outer thread 14 (see FIG. 6).
- Each of the two ends of the propeller shaft 11 is provided with a bearing cap 20 , two single-direction thrust bearings 30 , a bearing seat 40 , and a fixing member 50 .
- the bearing seat 40 is formed with a plurality of screw bores 41 .
- the bearing cap 20 is formed with a plurality of through holes 21 .
- the motorized vehicle 10 further comprises a plurality of locking screws 22 each extended through a respective one of the through holes 21 and each screwed into a respective one of the screw bores 41 , thereby fixing the bearing cap 20 on the bearing seat 40 .
- Each of the two single-direction thrust bearings 30 is mounted between the bearing seat 40 and the propeller shaft 11 .
- Each of the two single-direction thrust bearings 30 has an inner race formed with an inner keyway 31 .
- the motorized vehicle 10 further comprises a first key 32 secured in the inner keyway 31 of each of the two single-direction thrust bearings 30 and the keyway 13 of the propeller shaft 11 , so that each of the two single-direction thrust bearings 30 is combined with the propeller shaft 11 .
- Each of the two single-direction thrust bearings 30 has an outer race formed with an outer keyway 310 .
- the bearing seat 40 has two sides each formed with a keyway 42 .
- the motorized vehicle 10 further comprises two second keys 320 each secured in the outer keyway 310 of a respective one of the two single-direction thrust bearings 30 and the keyway 42 of the bearing seat 40 , so that each of the two single-direction thrust bearings 30 is combined with the bearing seat 40 .
- One of the two single-direction thrust bearings 30 is rested on and limited by the catch flange 12 of the propeller shaft 11 and the bearing cap 20 .
- the fixing member 50 is secured on the propeller shaft 11 and is rested on the other one of the two single-direction thrust bearings 30 .
- the fixing member 50 is formed with an inner thread 51 screwed on the outer thread 14 of the propeller shaft 11 , so that the fixing member 50 is fixed on the propeller shaft 11 .
- the bearing seat 40 has a periphery provided with a fixing board 43 , and the motorized vehicle 10 further comprises two rear wheels 60 each secured on the fixing board 43 of the respective bearing seat 40 .
- the fixing board 43 of the bearing seat 40 is formed with a plurality of through holes 44 .
- Each of the two rear wheels 60 is formed with a plurality of through holes 62 .
- the motorized vehicle 10 further comprises a plurality of locking bolts 45 each extended through a respective one of the through holes 44 of the fixing board 43 of the bearing seat 40 and a respective one of the through holes 62 of the respective rear wheel 60 , so that each of the two rear wheels 60 is fixed on the fixing board 43 of the respective bearing seat 40 .
- the two single-direction thrust bearings 30 located at a first end of the propeller shaft 11 has a rotation direction opposite to the normal rotation direction (when the motorized vehicle 10 is moved forward) of the propeller shaft 11 to drive the motorized vehicle 10 to move forward
- the two single-direction thrust bearings 30 located at a second end of the propeller shaft 11 has a rotation direction opposite to the reverse rotation direction (when the motorized vehicle 10 is moved backward) of the propeller shaft 11 to drive the motorized vehicle 10 to move backward.
- the single-direction thrust bearings located at one of the two rear wheels is used to drive the motorized vehicle to move forward, and the single-direction thrust bearings located between the other rear wheel is used to drive the motorized vehicle to move backward.
- the single-direction thrust bearing will idle, thereby producing a differential effect.
- the motorized vehicle is driven by the two rear wheels.
- the single-direction thrust bearings located at the left rear wheel is used to drive the motorized vehicle to move forward.
- the single-direction thrust bearings located at the right rear wheel idles.
- the single-direction thrust bearings located at the right rear wheel is used to drive the motorized vehicle to move backward.
- the single-direction thrust bearings located at the left rear wheel idles.
- the single-direction thrust bearings mounted on the two rear wheels form a differential effect when the motorized vehicle is turned or driven on an abnormal road condition.
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Motor Power Transmission Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44086103P | 2003-01-15 | 2003-01-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US20040231909A1 true US20040231909A1 (en) | 2004-11-25 |
Family
ID=32771871
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US10/440,861 Abandoned US20040231909A1 (en) | 2003-01-15 | 2003-05-19 | Motorized vehicle having forward and backward differential structure |
| US10/758,307 Active 2026-04-28 US7569345B2 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
| US12/478,632 Expired - Lifetime US8034565B2 (en) | 2003-01-15 | 2009-06-04 | Gene expression markers for breast cancer prognosis |
| US13/221,549 Expired - Lifetime US8206919B2 (en) | 2003-01-15 | 2011-08-30 | Gene expression markers for breast cancer prognosis |
| US13/473,526 Expired - Lifetime US8741605B2 (en) | 2003-01-15 | 2012-05-16 | Gene expression markers for breast cancer prognosis |
| US14/257,723 Active 2026-07-13 US9944990B2 (en) | 2003-01-15 | 2014-04-21 | Gene expression markers for breast cancer prognosis |
| US15/897,617 Expired - Lifetime US11220715B2 (en) | 2003-01-15 | 2018-02-15 | Gene expression markers for breast cancer prognosis |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US10/758,307 Active 2026-04-28 US7569345B2 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
| US12/478,632 Expired - Lifetime US8034565B2 (en) | 2003-01-15 | 2009-06-04 | Gene expression markers for breast cancer prognosis |
| US13/221,549 Expired - Lifetime US8206919B2 (en) | 2003-01-15 | 2011-08-30 | Gene expression markers for breast cancer prognosis |
| US13/473,526 Expired - Lifetime US8741605B2 (en) | 2003-01-15 | 2012-05-16 | Gene expression markers for breast cancer prognosis |
| US14/257,723 Active 2026-07-13 US9944990B2 (en) | 2003-01-15 | 2014-04-21 | Gene expression markers for breast cancer prognosis |
| US15/897,617 Expired - Lifetime US11220715B2 (en) | 2003-01-15 | 2018-02-15 | Gene expression markers for breast cancer prognosis |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US20040231909A1 (fr) |
| EP (4) | EP3059322B1 (fr) |
| JP (1) | JP4723472B2 (fr) |
| AT (1) | ATE470723T1 (fr) |
| AU (2) | AU2004205878B2 (fr) |
| CA (5) | CA3013889A1 (fr) |
| DE (1) | DE602004027600D1 (fr) |
| DK (3) | DK3059322T3 (fr) |
| ES (3) | ES2725892T3 (fr) |
| WO (1) | WO2004065583A2 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103465779A (zh) * | 2013-09-17 | 2013-12-25 | 哈尔滨工程大学 | 双引擎全向四驱行进机构 |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8044259B2 (en) * | 2000-08-03 | 2011-10-25 | The Regents Of The University Of Michigan | Determining the capability of a test compound to affect solid tumor stem cells |
| US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| US20060062786A1 (en) * | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
| US7361341B2 (en) * | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
| US20050214209A1 (en) * | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
| US20050129616A1 (en) * | 2001-05-25 | 2005-06-16 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
| US20090226429A1 (en) * | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
| US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
| CA2471140A1 (fr) * | 2001-12-20 | 2003-07-03 | Human Genome Sciences, Inc. | Anticorps se liant de maniere immunospecifique a des recepteurs trail |
| WO2003078662A1 (fr) * | 2002-03-13 | 2003-09-25 | Genomic Health | Profilage d'expression genique dans des tissus tumoraux ponctionnes |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| WO2005039382A2 (fr) * | 2003-06-24 | 2005-05-06 | Genomic Health | Prediction de probabilite de la recurrence d'un cancer |
| ES2651849T3 (es) | 2003-07-10 | 2018-01-30 | Genomic Health, Inc. | Algoritmo del perfil de expresión y test para el pronóstico del cáncer |
| US20050112622A1 (en) * | 2003-08-11 | 2005-05-26 | Ring Brian Z. | Reagents and methods for use in cancer diagnosis, classification and therapy |
| US20060003391A1 (en) * | 2003-08-11 | 2006-01-05 | Ring Brian Z | Reagents and methods for use in cancer diagnosis, classification and therapy |
| US7871769B2 (en) | 2004-04-09 | 2011-01-18 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| US20080131916A1 (en) * | 2004-08-10 | 2008-06-05 | Ring Brian Z | Reagents and Methods For Use In Cancer Diagnosis, Classification and Therapy |
| MX2007001640A (es) * | 2004-08-10 | 2007-07-25 | Univ Cardiff | Metodos y kit para el pronostico de cancer de mama. |
| AU2005289756B2 (en) * | 2004-09-22 | 2011-10-13 | Tripath Imaging, Inc. | Methods and computer program products for analysis and optimization of marker candidates for cancer prognosis |
| US8065093B2 (en) * | 2004-10-06 | 2011-11-22 | Agency For Science, Technology, And Research | Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers |
| WO2006052862A1 (fr) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Prediction de reaction a la chimiotherapie au moyen de marqueurs d'expression genique |
| EP1815014B1 (fr) * | 2004-11-05 | 2012-03-21 | Genomic Health, Inc. | Indicateurs moléculaires de pronostic du cancer du sein et prédiction de réponse du traitement |
| KR20070085855A (ko) * | 2004-12-07 | 2007-08-27 | 제넨테크, 인크. | Her 억제제를 이용한 치료를 위한 환자 선택 방법 |
| BRPI0518104B8 (pt) | 2005-01-21 | 2021-05-25 | Genentech Inc | artigo industrializado e uso de anticorpo her2 |
| US20060188509A1 (en) | 2005-02-23 | 2006-08-24 | Genentech, Inc. | Extending time to disease progression or survival in cancer patients |
| US20080275652A1 (en) * | 2005-05-13 | 2008-11-06 | Universite Libre De Bruxelles | Gene-based algorithmic cancer prognosis |
| JP2006316040A (ja) | 2005-05-13 | 2006-11-24 | Genentech Inc | Herceptin(登録商標)補助療法 |
| WO2006135886A2 (fr) * | 2005-06-13 | 2006-12-21 | The Regents Of The University Of Michigan | Compositions et methodes pour le traitement et le diagnostic du cancer |
| JP2009505658A (ja) * | 2005-08-24 | 2009-02-12 | ブリストル−マイヤーズ スクイブ カンパニー | 上皮増殖因子受容体モデュレーターに対する感受性を決定するためのバイオマーカーおよび方法 |
| JP5129149B2 (ja) | 2005-10-31 | 2013-01-23 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 癌を処置および診断するための組成物および方法 |
| WO2007141595A2 (fr) * | 2005-11-10 | 2007-12-13 | Aurelium Biopharma Inc. | Diagnostic tissulaire du cancer du sein |
| TW200731980A (en) * | 2005-12-29 | 2007-09-01 | Alcon Mfg Ltd | RNAi-mediated inhibition of HIF1A for treatment of ocular angiogenesis |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| CL2007001571A1 (es) * | 2006-06-02 | 2008-05-16 | Glaxosmithkline Biolog Sa | Perfil genico indicativo de probabilidad aumentada de que un paciente responda o no a una inmunoterapia; uso de dicho perfil; procedimiento de identificacion del perfil; uso de sonda para identificar la expresion diferencial de al menos un gen de act |
| WO2008063521A2 (fr) * | 2006-11-13 | 2008-05-29 | The General Hospital Corporation | Système d'évaluation clinique basé sur des gènes |
| WO2008092002A2 (fr) | 2007-01-24 | 2008-07-31 | The Regents Of The University Of Michigan | Compositions et procédés pour le traitement et le diagnostic du cancer du pancréas |
| PE20090681A1 (es) | 2007-03-02 | 2009-06-10 | Genentech Inc | Prediccion de respuesta a un inhibidor her |
| KR20160061439A (ko) | 2007-03-28 | 2016-05-31 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
| WO2008150512A2 (fr) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Procédés pour identifier une plus grande probabilité de récidive du cancer du sein |
| EP2592156B1 (fr) | 2007-06-08 | 2016-04-20 | Genentech, Inc. | Marqueurs d'expression de gène de résistance tumorale à un traitement par inhibiteur HER2 |
| US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
| AU2008289148A1 (en) * | 2007-08-16 | 2009-02-26 | Aventis Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| GB0720113D0 (en) * | 2007-10-15 | 2007-11-28 | Cambridge Cancer Diagnostics L | Diagnostic, prognostic and predictive testing for cancer |
| WO2009067655A2 (fr) * | 2007-11-21 | 2009-05-28 | University Of Florida Research Foundation, Inc. | Procédés de sélection de particularités par apprentissage local ; marqueurs de pronostic du cancer du sein et de la prostate |
| EP2065475A1 (fr) * | 2007-11-30 | 2009-06-03 | Siemens Healthcare Diagnostics GmbH | Procédé pour prédire des thérapies contre les tumeurs avec des irrégulières d'expression d'au moins un ligand VEGF et/ou d'au moins un récepteur ErbB |
| US20110130296A1 (en) * | 2008-03-14 | 2011-06-02 | The Regents Of The University Of California | Multi-gene classifiers and prognostic indicators for cancers |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| WO2010045234A1 (fr) * | 2008-10-14 | 2010-04-22 | University Of Louisville Research Foundation, Inc. | Procédés d’optimisation du traitement des cancers du sein positifs aux récepteurs des œstrogènes |
| GB0821787D0 (en) * | 2008-12-01 | 2009-01-07 | Univ Ulster | A genomic-based method of stratifying breast cancer patients |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| EP2435071A1 (fr) | 2009-05-29 | 2012-04-04 | F. Hoffmann-La Roche AG | Modulateurs de la signalisation her2 chez des patients exprimant her2 souffrant d'un cancer de l'estomac |
| CA2764041A1 (fr) * | 2009-05-29 | 2011-01-13 | Baylor College Of Medicine | Reparation de l'adn ou signature de gene de type brca1 |
| WO2010146059A2 (fr) | 2009-06-16 | 2010-12-23 | F. Hoffmann-La Roche Ag | Biomarqueurs pour une thérapie par inhibiteur d'igf-1r |
| EP2275569A1 (fr) * | 2009-07-17 | 2011-01-19 | Centre Leon Berard | ZNF217, un nouveau biomarqueur pour le pronostic et la prédiction de phénotypes récurrents, invasifs et métastatiques du cancer |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| AU2010321829B2 (en) * | 2009-11-23 | 2015-07-30 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
| WO2011088137A2 (fr) * | 2010-01-12 | 2011-07-21 | H. Lee Moffitt Cancer Center & Research Institute | Signature de gènes impliqués dans la transduction du signal bad |
| WO2011107819A1 (fr) * | 2010-03-01 | 2011-09-09 | Adelbio | Procédés destinés à prédire l'évolution d'un cancer du sein, et/ou le risque de rechute, la réponse ou la survie d'un patient souffrant de celui-ci |
| WO2011146568A1 (fr) | 2010-05-19 | 2011-11-24 | Genentech, Inc. | Prédiction de réponses à un inhibiteur de her |
| EP2591126B1 (fr) | 2010-07-07 | 2020-12-30 | Myriad Genetics, Inc. | Signatures génétiques utilisées pour le pronostic du cancer |
| AU2011274422B2 (en) | 2010-07-09 | 2016-02-11 | Somalogic Operating Co., Inc. | Lung cancer biomarkers and uses thereof |
| BR112013003391B8 (pt) | 2010-08-13 | 2022-10-25 | Somalogic Inc | Método para diagnosticar câncer pancreático em um indivíduo |
| DK2603600T3 (da) | 2010-08-13 | 2019-03-04 | Aileron Therapeutics Inc | Peptidomimetiske makrocyklusser |
| US9605319B2 (en) | 2010-08-30 | 2017-03-28 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| SG190867A1 (en) | 2010-11-23 | 2013-07-31 | Krisani Biosciences P Ltd | Method and system for prognosis and treatment of diseases using portfolio of genes |
| WO2012109233A2 (fr) * | 2011-02-07 | 2012-08-16 | Board Of Regents, The University Of Texas System | Procédés de prédiction du risque de récidive chez des patients atteints d'un cancer du sein |
| RU2639523C2 (ru) | 2011-10-18 | 2017-12-21 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы и их применение |
| WO2013070521A1 (fr) * | 2011-11-08 | 2013-05-16 | Genomic Health, Inc. | Méthode de prédiction du pronostic du cancer du sein |
| EP2788500A1 (fr) | 2011-12-09 | 2014-10-15 | F.Hoffmann-La Roche Ag | Identification de non-répondeurs aux inhibiteurs de her2 |
| CA2864120A1 (fr) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Macrocycles peptidomimetiques reticules par triazole et par thioether |
| WO2013170174A1 (fr) | 2012-05-10 | 2013-11-14 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Méthode de diagnostic, de traitement et de détermination de la progression et de la survie de cellules cancéreuses à l'aide de la signature génique de l'antagoniste bcl-2 de la voie de la mort cellulaire (bad) |
| US9890430B2 (en) | 2012-06-12 | 2018-02-13 | Washington University | Copy number aberration driven endocrine response gene signature |
| US9604919B2 (en) | 2012-11-01 | 2017-03-28 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
| EP2920322B1 (fr) | 2012-11-16 | 2023-01-11 | Myriad Genetics, Inc. | Signatures génétiques utilisées en vue du pronostic d'un cancer |
| BR112015012644A2 (pt) | 2012-11-30 | 2017-12-19 | Hoffmann La Roche | método para determinar a necessidade de um paciente com câncer, método de tratamento do câncer, composição farmacêutica, uso de um ácido nucleico ou anticorpo e kit; |
| WO2014113641A1 (fr) | 2013-01-18 | 2014-07-24 | Kline Ellis | Régime de glycosidase sélective pour la programmation immunitaire et le traitement du cancer |
| US10386370B2 (en) | 2013-02-11 | 2019-08-20 | Incuron, Inc. | Use of facilitates chromatin transcription complex (FACT) in cancer |
| CN103558382B (zh) * | 2013-10-28 | 2015-11-18 | 深圳市第二人民医院 | Ccne1基因在检测上尿路上皮癌中的应用 |
| CN103558383B (zh) * | 2013-10-28 | 2015-11-18 | 深圳市第二人民医院 | Aldh2基因在检测上尿路上皮癌中的应用 |
| KR20150088433A (ko) | 2014-01-24 | 2015-08-03 | 삼성전자주식회사 | c-Met 저해제의 효능 예측을 위한 바이오마커 TFF1 |
| CA2947624A1 (fr) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Signatures genetiques utilisees en vue du pronostic d'un cancer |
| US10633710B2 (en) | 2014-08-15 | 2020-04-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for characterizing cancer |
| SG11201702223UA (en) | 2014-09-24 | 2017-04-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| JP2018503595A (ja) | 2014-09-24 | 2018-02-08 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | ペプチド模倣大環状分子およびその製剤 |
| JP7065609B6 (ja) | 2014-10-24 | 2022-06-06 | コーニンクレッカ フィリップス エヌ ヴェ | 複数の細胞シグナル伝達経路活性を用いる治療応答の医学的予後及び予測 |
| CN108064380A (zh) | 2014-10-24 | 2018-05-22 | 皇家飞利浦有限公司 | 使用多种细胞信号传导途径活性的医学预后和治疗反应的预测 |
| CN107077536B (zh) | 2014-10-24 | 2021-09-28 | 皇家飞利浦有限公司 | 使用靶基因表达的数学建模评价TGF-β细胞信号传导途径的活性 |
| US10253067B2 (en) | 2015-03-20 | 2019-04-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| EP3073268A1 (fr) | 2015-03-27 | 2016-09-28 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Panel de biomarqueurs pour le diagnostic du cancer |
| US11450409B2 (en) | 2015-08-14 | 2022-09-20 | Innosign B.V. | Determination of NFkB pathway activity using unique combination of target genes |
| CN107058523A (zh) * | 2017-03-21 | 2017-08-18 | 温州迪安医学检验所有限公司 | 一种乳腺癌复发风险评估21基因检测引物及其应用 |
| EP3461915A1 (fr) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Évaluation de l'activité de la voie de signalisation cellulaire jak-stat1/2 faisant appel à une modélisation mathématique de l'expression du gène cible |
| EP3461916A1 (fr) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Évaluation de l'activité de la voie de signalisation cellulaire jak-stat3 utilisant une modélisation mathématique de l'expression du gène cible |
| EP3502279A1 (fr) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Évaluation de l'activité de la voie de signalisation cellulaire mapk-ap 1 faisant appel à une modélisation mathématique de l'expression du gène cible |
| CN110045120A (zh) * | 2018-01-15 | 2019-07-23 | 长庚医疗财团法人基隆长庚纪念医院 | 检测生物样品中wisp1的浓度在制备用于乳癌筛检及侦测复发的检测试剂盒及其应用 |
| WO2020013355A1 (fr) * | 2018-07-10 | 2020-01-16 | 서울대학교산학협력단 | Composition pour prédire le pronostic d'une tumeur phyllode maligne et kit la comprenant |
| WO2021030460A1 (fr) * | 2019-08-12 | 2021-02-18 | Baylor College Of Medicine | Procédés protéogénomiques de diagnostic du cancer |
| CN113862363A (zh) * | 2021-10-27 | 2021-12-31 | 中山大学附属第一医院 | 免疫相关基因在乳腺癌预后的试剂盒和系统中的应用 |
| CN114480650A (zh) * | 2022-02-08 | 2022-05-13 | 深圳市陆为生物技术有限公司 | 一种预测三阴乳腺癌临床预后复发风险的标志物及模型 |
| WO2025076607A1 (fr) * | 2023-10-09 | 2025-04-17 | Liqsci Biotecnologia Ltda | Procédé in vitro pour le diagnostic et/ou le pronostic de tumeurs dans des échantillons liquides, kit et procédé in vitro pour la surveillance du tableau clinique |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6378397B1 (en) * | 2000-10-25 | 2002-04-30 | Jenn Jianq Co., Ltd. | Differential gearing device |
| US6655515B2 (en) * | 2001-05-24 | 2003-12-02 | Tecumseh Products Company | Modular bi-directional overrunning wheel clutch |
Family Cites Families (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4699877A (en) | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| IE56509B1 (en) | 1982-11-04 | 1991-08-28 | Univ California | Methods for oncogenic detection |
| USRE35491E (en) | 1982-11-04 | 1997-04-08 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US7838216B1 (en) | 1986-03-05 | 2010-11-23 | The United States Of America, As Represented By The Department Of Health And Human Services | Human gene related to but distinct from EGF receptor gene |
| US5015568A (en) | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
| US5202429A (en) | 1986-07-09 | 1993-04-13 | The Wistar Institute | DNA molecules having human BCL-2 gene sequences |
| US4968603A (en) | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
| US5831066A (en) | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
| US5922855A (en) * | 1993-12-17 | 1999-07-13 | Oregon Health Sciences University | Mammalian DNA mismatch repair genes MLH1 and PMS1 |
| US6037134A (en) * | 1994-03-07 | 2000-03-14 | New York University Medical Center | Methods that detect compounds that disrupt receptor tyrosine kinase/GRB-7 complexes |
| US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
| US5858678A (en) | 1994-08-02 | 1999-01-12 | St. Louis University | Apoptosis-regulating proteins |
| US5830753A (en) | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
| WO1998004689A1 (fr) | 1995-07-31 | 1998-02-05 | Urocor, Inc. | Biomarqueurs et cibles de diagnostic, de pronostic et de traitement du cancer de la prostate |
| US6218529B1 (en) * | 1995-07-31 | 2001-04-17 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer |
| US6716575B2 (en) | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| KR100459052B1 (ko) | 1995-12-18 | 2005-01-15 | 서젠, 인크. | Aur-1및(또는)aur-2관련질병의진단및치료 |
| US5670325A (en) | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| US5741650A (en) | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
| US5821082A (en) | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
| US6143529A (en) | 1996-08-14 | 2000-11-07 | Exact Laboratories, Inc. | Methods for improving sensitivity and specificity of screening assays |
| US6146828A (en) | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
| US5928870A (en) | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6020137A (en) | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
| US5952178A (en) | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
| US6100029A (en) | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
| US5861278A (en) | 1996-11-01 | 1999-01-19 | Genetics Institute, Inc. | HNF3δ compositions |
| JP4672092B2 (ja) | 1996-11-20 | 2011-04-20 | イェール ユニバーシティ | 細胞アポトーシスを阻害するタンパク質であるサービビン(Survivin)、およびその調節 |
| US5830665A (en) | 1997-03-03 | 1998-11-03 | Exact Laboratories, Inc. | Contiguous genomic sequence scanning |
| US6033893A (en) | 1997-06-26 | 2000-03-07 | Incyte Pharmaceuticals, Inc. | Human cathepsin |
| WO1999002714A1 (fr) | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reactifs et procedes utilises pour detecter les maladies du sein |
| EP1025220B1 (fr) * | 1997-10-21 | 2007-01-03 | The University Court Of The University Of Glasgow | JMY QUI EST UN COACTIVATEUR DE p300/CBP, ACIDE NUCLEIQUE CODANT JMY ET LEURS UTILISATIONS |
| WO1999044062A1 (fr) * | 1998-02-25 | 1999-09-02 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | Arrangements cellulaires permettant une definition de profil moleculaire rapide |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| WO1999064627A2 (fr) | 1998-06-06 | 1999-12-16 | Genostic Pharma Limited | Sondes utilisees pour profilage genetique |
| WO1999064626A2 (fr) | 1998-06-06 | 1999-12-16 | Genostic Pharma Limited | Sondes permettant de determiner un profil genetique |
| US6696558B2 (en) | 1998-09-09 | 2004-02-24 | The Burnham Institute | Bag proteins and nucleic acid molecules encoding them |
| CA2348003A1 (fr) | 1998-09-23 | 2000-04-20 | Cleveland Clinic Foundation | Nouveaux genes stimules ou reprimes par l'interferon |
| US6251601B1 (en) | 1999-02-02 | 2001-06-26 | Vysis, Inc. | Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays |
| US9534254B1 (en) * | 1999-02-02 | 2017-01-03 | Abbott Molecular Inc. | Patient stratification for cancer therapy based on genomic DNA microarray analysis |
| AU3246200A (en) | 1999-02-25 | 2000-09-14 | Boris Bilynsky | Nucleic acid molecules associated with melanoma and thyroid tumors |
| US20020039764A1 (en) | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
| AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US6960439B2 (en) | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US6692916B2 (en) | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US6326148B1 (en) | 1999-07-12 | 2001-12-04 | The Regents Of The University Of California | Detection of copy number changes in colon cancer |
| US6710170B2 (en) | 1999-09-10 | 2004-03-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| US6271002B1 (en) | 1999-10-04 | 2001-08-07 | Rosetta Inpharmatics, Inc. | RNA amplification method |
| AU777096B2 (en) | 1999-10-06 | 2004-09-30 | Regents Of The University Of California, The | Differentially expressed genes associated with Her-2/neu overexpression |
| EP2228446A1 (fr) | 1999-12-01 | 2010-09-15 | Genentech, Inc. | Polypeptides secrétés et transmembranaires et acides nucléiques codant pour ceux-ci |
| US6750013B2 (en) | 1999-12-02 | 2004-06-15 | Protein Design Labs, Inc. | Methods for detection and diagnosing of breast cancer |
| US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| WO2001051664A2 (fr) * | 2000-01-12 | 2001-07-19 | Dana-Farber Cancer Institute, Inc. | Procede de detection et de caracterisation d'un neoplasme |
| AU2001232485A1 (en) | 2000-01-13 | 2001-07-24 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
| US6322986B1 (en) | 2000-01-18 | 2001-11-27 | Albany Medical College | Method for colorectal cancer prognosis and treatment selection |
| CA2398107C (fr) | 2000-01-28 | 2013-11-19 | Althea Technologies, Inc. | Procedes d'analyse de l'expression genique |
| WO2001055206A1 (fr) | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Acides nucleiques, proteines et anticorps |
| WO2001070979A2 (fr) | 2000-03-21 | 2001-09-27 | Millennium Pharmaceuticals, Inc. | Nouveaux genes, compositions, trousses et methodes d'identification, de verification, de prevention et de traitement du cancer des ovaires |
| WO2001075159A2 (fr) | 2000-03-31 | 2001-10-11 | Sir Mortimer B. Davis Jewish General Hospital | Microechantillons de genes regulateurs |
| AU2001266787A1 (en) | 2000-06-07 | 2002-01-08 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| JP2004504059A (ja) | 2000-07-21 | 2004-02-12 | グローバル ジェノミクス アクティエボラーグ | 転写された遺伝子を分析、及び同定するための方法、及びフインガープリント法 |
| WO2002008282A2 (fr) | 2000-07-26 | 2002-01-31 | Stanford University | Proteine bstp-ras/rerg et reactifs apparentes, procedes d'utilisation de ces derniers |
| AU2001278011A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ecg1 protein and related reagents and methods of use thereof |
| WO2002008765A2 (fr) | 2000-07-26 | 2002-01-31 | Stanford University | Marqueurs basocellulaires du cancer du sein et leurs utilisations |
| WO2002010436A2 (fr) * | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Classification de pronostics de cancer du sein |
| US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
| US6602670B2 (en) | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| US6582919B2 (en) | 2001-06-11 | 2003-06-24 | Response Genetics, Inc. | Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates |
| JP2004537261A (ja) * | 2000-12-08 | 2004-12-16 | イプソゲン | 候補遺伝子のアレイを用いた原発性乳がんの遺伝子発現プロファイリング |
| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| US7776518B2 (en) | 2001-01-12 | 2010-08-17 | Yale University | Detection of survivin in the biological fluids of cancer patients |
| JP4368110B2 (ja) | 2001-01-12 | 2009-11-18 | エール ユニヴァーシティ | 癌患者の生物学的流体中のサバイビンの検出 |
| AU2002245317A1 (en) | 2001-01-24 | 2002-08-06 | Protein Design Labs | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer |
| US20070015148A1 (en) | 2001-01-25 | 2007-01-18 | Orr Michael S | Gene expression profiles in breast tissue |
| NZ528205A (en) | 2001-03-12 | 2006-09-29 | Monogen Inc | Cell-based detection and differentiation of disease status in a cytological sample using a panel comprising a plurality of probes |
| US20050260572A1 (en) * | 2001-03-14 | 2005-11-24 | Kikuya Kato | Method of predicting cancer |
| ATE503023T1 (de) | 2001-06-18 | 2011-04-15 | Rosetta Inpharmatics Llc | Diagnose und prognose von brustkrebspatientinnen |
| WO2003011897A1 (fr) | 2001-07-27 | 2003-02-13 | The Regents Of The University Of California | Modulation de l'hereguline et de l'interaction du recepteur her3 |
| US6898531B2 (en) * | 2001-09-05 | 2005-05-24 | Perlegen Sciences, Inc. | Algorithms for selection of primer pairs |
| US20040009489A1 (en) | 2001-09-28 | 2004-01-15 | Golub Todd R. | Classification of lung carcinomas using gene expression analysis |
| KR20040064275A (ko) | 2001-11-09 | 2004-07-16 | 소스 프리시전 메디슨, 인코포레이티드 | 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인 |
| US20030198972A1 (en) | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| WO2003078662A1 (fr) | 2002-03-13 | 2003-09-25 | Genomic Health | Profilage d'expression genique dans des tissus tumoraux ponctionnes |
| EP1492871A2 (fr) | 2002-03-28 | 2005-01-05 | QLT Inc. | Proteines kinases associees au cancer et leurs utilisations |
| EP1900827A3 (fr) | 2002-05-21 | 2008-04-16 | Bayer HealthCare AG | Procédés et compositions pour la prédiction, le diagnostic, le pronostic et la prévention et le traitement de néoplasies malignes |
| EP2284266B1 (fr) * | 2002-11-14 | 2013-11-06 | Thermo Fisher Scientific Biosciences Inc. | Molécule siRNA anti tp53 |
| EP1998177A3 (fr) * | 2003-01-06 | 2009-02-18 | Wyeth | Compositions et procédés de diagnostic et de traitement des cancers du colon |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| ATE412779T1 (de) | 2003-02-20 | 2008-11-15 | Genomic Health Inc | Benutzung von intronischen rna sequenzen zur quantifizierung der genexpression |
| WO2004111603A2 (fr) | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Marqueurs de l'expression genetique permettant de predire la reponse une chimiotherapie |
| WO2005039382A2 (fr) * | 2003-06-24 | 2005-05-06 | Genomic Health | Prediction de probabilite de la recurrence d'un cancer |
| ES2651849T3 (es) | 2003-07-10 | 2018-01-30 | Genomic Health, Inc. | Algoritmo del perfil de expresión y test para el pronóstico del cáncer |
| US7871769B2 (en) | 2004-04-09 | 2011-01-18 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| WO2006052862A1 (fr) | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Prediction de reaction a la chimiotherapie au moyen de marqueurs d'expression genique |
| EP1815014B1 (fr) | 2004-11-05 | 2012-03-21 | Genomic Health, Inc. | Indicateurs moléculaires de pronostic du cancer du sein et prédiction de réponse du traitement |
| CA2620936A1 (fr) | 2005-09-01 | 2007-03-08 | Precision Therapeutics, Inc. | Tests de chimiosensibilite faisant appel a des cellules tumorales presentant des caracteristiques phenotypiques persistantes |
| EP1777523A1 (fr) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthode pour pronostiquer la progression d'un cancer et les résultats du patient et les moyens pour performer la méthode |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| AU2008289148A1 (en) | 2007-08-16 | 2009-02-26 | Aventis Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| EP2641977B1 (fr) | 2008-05-12 | 2014-09-03 | Genomic Health, Inc. | Tests pour prédire une sensibilité de patients atteints de cancer à des options de traitement de chimiothérapie |
| EP2448973A1 (fr) | 2009-07-02 | 2012-05-09 | Basf Se | Dispersions co-agglomérées de polymères de latex et leurs procédés de préparation et d utilisation |
| AU2010321829B2 (en) | 2009-11-23 | 2015-07-30 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
-
2003
- 2003-05-19 US US10/440,861 patent/US20040231909A1/en not_active Abandoned
-
2004
- 2004-01-14 CA CA3013889A patent/CA3013889A1/fr not_active Abandoned
- 2004-01-14 EP EP15190640.1A patent/EP3059322B1/fr not_active Expired - Lifetime
- 2004-01-14 CA CA2829476A patent/CA2829476C/fr not_active Expired - Lifetime
- 2004-01-14 CA CA2829477A patent/CA2829477C/fr not_active Expired - Lifetime
- 2004-01-14 ES ES15190640T patent/ES2725892T3/es not_active Expired - Lifetime
- 2004-01-14 DK DK15190640.1T patent/DK3059322T3/da active
- 2004-01-14 CA CA2829472A patent/CA2829472C/fr not_active Expired - Lifetime
- 2004-01-14 DE DE602004027600T patent/DE602004027600D1/de not_active Expired - Lifetime
- 2004-01-14 ES ES10162868.3T patent/ES2561179T3/es not_active Expired - Lifetime
- 2004-01-14 ES ES04702177T patent/ES2346967T3/es not_active Expired - Lifetime
- 2004-01-14 EP EP04702177A patent/EP1587957B1/fr not_active Expired - Lifetime
- 2004-01-14 EP EP10162867A patent/EP2230318A1/fr not_active Ceased
- 2004-01-14 US US10/758,307 patent/US7569345B2/en active Active
- 2004-01-14 WO PCT/US2004/000985 patent/WO2004065583A2/fr not_active Ceased
- 2004-01-14 AT AT04702177T patent/ATE470723T1/de active
- 2004-01-14 EP EP10162868.3A patent/EP2230319B1/fr not_active Expired - Lifetime
- 2004-01-14 AU AU2004205878A patent/AU2004205878B2/en not_active Expired
- 2004-01-14 CA CA2513117A patent/CA2513117C/fr not_active Expired - Lifetime
- 2004-01-14 JP JP2006500964A patent/JP4723472B2/ja not_active Expired - Lifetime
- 2004-01-14 DK DK04702177.9T patent/DK1587957T3/da active
- 2004-01-14 DK DK10162868.3T patent/DK2230319T3/en active
-
2009
- 2009-06-04 US US12/478,632 patent/US8034565B2/en not_active Expired - Lifetime
- 2009-11-16 AU AU2009238287A patent/AU2009238287B2/en not_active Expired
-
2011
- 2011-08-30 US US13/221,549 patent/US8206919B2/en not_active Expired - Lifetime
-
2012
- 2012-05-16 US US13/473,526 patent/US8741605B2/en not_active Expired - Lifetime
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2014
- 2014-04-21 US US14/257,723 patent/US9944990B2/en active Active
-
2018
- 2018-02-15 US US15/897,617 patent/US11220715B2/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6378397B1 (en) * | 2000-10-25 | 2002-04-30 | Jenn Jianq Co., Ltd. | Differential gearing device |
| US6655515B2 (en) * | 2001-05-24 | 2003-12-02 | Tecumseh Products Company | Modular bi-directional overrunning wheel clutch |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103465779A (zh) * | 2013-09-17 | 2013-12-25 | 哈尔滨工程大学 | 双引擎全向四驱行进机构 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AS | Assignment |
Owner name: TAIWAN POWER INDUSTRIAL CO., LTD., TAIWAN Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:LUH, TAI-YANG;REEL/FRAME:014095/0612 Effective date: 20030505 |
|
| STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |