[go: up one dir, main page]

UA97092C2 - T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение - Google Patents

T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение

Info

Publication number
UA97092C2
UA97092C2 UAA200712736A UAA200712736A UA97092C2 UA 97092 C2 UA97092 C2 UA 97092C2 UA A200712736 A UAA200712736 A UA A200712736A UA A200712736 A UAA200712736 A UA A200712736A UA 97092 C2 UA97092 C2 UA 97092C2
Authority
UA
Ukraine
Prior art keywords
laminin receptor
oncofetal antigen
receptor protein
cell epitopes
medical uses
Prior art date
Application number
UAA200712736A
Other languages
English (en)
Ukrainian (uk)
Inventor
Маттиас Цайс
Original Assignee
Имматикс Биотекнолоджис Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Имматикс Биотекнолоджис Гмбх filed Critical Имматикс Биотекнолоджис Гмбх
Publication of UA97092C2 publication Critical patent/UA97092C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Данное изобретение относится к методам иммунотерапии, а также к молекулам и клеткам, которые применяются в иммунотерапевтических методах, к новой пептидной последовательности, полученной из молекул HLA I или II класса раково-эмбрионального антиген-незрелого рецептора ламинина (OFA/ilr) человека, который может использоваться в вакцинных или других фармацевтических композициях для стимулирования противоопухолевых иммунных реакций.
UAA200712736A 2005-04-26 2006-04-26 T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение UA97092C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05009095A EP1717245B1 (en) 2005-04-26 2005-04-26 T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof
PCT/EP2006/003888 WO2006114307A1 (en) 2005-04-26 2006-04-26 T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof

Publications (1)

Publication Number Publication Date
UA97092C2 true UA97092C2 (ru) 2012-01-10

Family

ID=34935739

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200712736A UA97092C2 (ru) 2005-04-26 2006-04-26 T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение

Country Status (14)

Country Link
US (1) US7968097B2 (ru)
EP (2) EP1717245B1 (ru)
JP (1) JP4870751B2 (ru)
CN (1) CN101166759B (ru)
AT (1) ATE512160T1 (ru)
AU (1) AU2006239505B2 (ru)
BR (1) BRPI0610841A2 (ru)
CA (1) CA2606088C (ru)
EA (1) EA013598B1 (ru)
ES (1) ES2367643T3 (ru)
NO (1) NO20076041L (ru)
NZ (1) NZ563432A (ru)
UA (1) UA97092C2 (ru)
WO (1) WO2006114307A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2565578T3 (es) * 2002-08-02 2016-04-05 South Alabama Medical Science Foundation Vacunas contra el cáncer que contienen epítopos de antígeno oncofetal
US20090004213A1 (en) 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
WO2009015841A1 (en) * 2007-07-27 2009-02-05 Immatics Biotechnologies Gmbh Composition of tumour-associated peptides and related anti-cancer vaccine
SI2113253T1 (sl) * 2008-04-30 2010-06-30 Immatics Biotechnologies Gmbh Nove formulacije s tumorjem povezanih peptidov ki se vežejo na molekule humanega levkocitnega antigena HLA razreda I ali II za cepiva
CN102574925A (zh) * 2009-03-26 2012-07-11 昆腾免疫有限公司 用于诊断及临床应用的癌胚胎抗原/未成熟层粘连蛋白受体抗体
US20130052211A1 (en) * 2009-07-09 2013-02-28 South Alabama Medical Science Vaccines with oncofetal antigen/ilrp-loaded autologous dendritic cells and uses thereof
WO2011024791A1 (ja) * 2009-08-25 2011-03-03 タカラバイオ株式会社 レチノイン酸存在下でのｔ細胞集団の製造方法
EP2330122A1 (en) 2009-12-02 2011-06-08 Asklepios Kliniken Hamburg Gmbh OFA/iLRP derived modified peptide
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
EP4317432A3 (en) 2016-12-08 2024-04-17 Immatics Biotechnologies GmbH T cell receptors with improved pairing
CN111533796A (zh) * 2017-04-10 2020-08-14 伊玛提克斯生物技术有限公司 用于癌症免疫治疗的肽及其肽组合物
WO2018224166A1 (en) * 2017-06-09 2018-12-13 Biontech Rna Pharmaceuticals Gmbh Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
WO2019222760A1 (en) * 2018-05-18 2019-11-21 Children's National Medical Center Improved targeted t-cell therapy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2195642A1 (en) 1994-07-27 1996-02-08 Andreas Suhrbier Polyepitope vaccines
CA2243235C (en) 1996-01-17 2010-08-10 Imperial College Innovations Limited Immunotherapy using cytotoxic t lymphocytes (ctl)
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
ES2565578T3 (es) 2002-08-02 2016-04-05 South Alabama Medical Science Foundation Vacunas contra el cáncer que contienen epítopos de antígeno oncofetal
AU2003295328A1 (en) 2002-10-02 2004-04-23 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2005017102A2 (en) * 2003-05-30 2005-02-24 Diadexus, Inc. Compositions, splice variants and methods relating to ovarian specific nucleic acids and proteins
US20080206270A1 (en) * 2004-07-08 2008-08-28 Minev Boris R Enhancing Class I Antigen Presentation With Synthetic Sequences

Also Published As

Publication number Publication date
EA200702202A1 (ru) 2008-04-28
ATE512160T1 (de) 2011-06-15
CN101166759A (zh) 2008-04-23
CN101166759B (zh) 2012-09-05
AU2006239505B2 (en) 2012-05-10
US20090041794A1 (en) 2009-02-12
JP4870751B2 (ja) 2012-02-08
EP1717245B1 (en) 2011-06-08
JP2008538901A (ja) 2008-11-13
EP1874810A1 (en) 2008-01-09
EP1717245A1 (en) 2006-11-02
NO20076041L (no) 2007-11-23
US7968097B2 (en) 2011-06-28
EA013598B1 (ru) 2010-06-30
NZ563432A (en) 2010-11-26
BRPI0610841A2 (pt) 2010-07-27
CA2606088A1 (en) 2006-11-02
CA2606088C (en) 2015-05-26
WO2006114307A1 (en) 2006-11-02
AU2006239505A1 (en) 2006-11-02
ES2367643T3 (es) 2011-11-07

Similar Documents

Publication Publication Date Title
NO20076041L (no) Identifisering av HLA-A2-presenterte T-celleepitoper som er avledet fra onkofotalt antigen-umodent lamininreseptorprotein og anvendelser derav
DK1760089T3 (da) Tumor-associeret peptides bindende til human leukocyte antigen (HLA) class I eller II molecules og relateret anti-cancer vaccine
EA200800677A1 (ru) Опухолеассоциированные пептиды, беспорядочно связывающиеся с молекулами класса ii человеческого лейкоцитарного антигена (hla)
PL1794190T3 (pl) Immunogenne epitopy komórek pomocniczych T pochodzące z ludzkich antygenów nowotworowych oraz sposoby stosowania tych epitopów w immunoterapii