UA93254C2 - Способ получения препарата инсулина для перорального применения - Google Patents
Способ получения препарата инсулина для перорального примененияInfo
- Publication number
- UA93254C2 UA93254C2 UAA200900222A UAA200900222A UA93254C2 UA 93254 C2 UA93254 C2 UA 93254C2 UA A200900222 A UAA200900222 A UA A200900222A UA A200900222 A UAA200900222 A UA A200900222A UA 93254 C2 UA93254 C2 UA 93254C2
- Authority
- UA
- Ukraine
- Prior art keywords
- insulin preparation
- ranges
- producing insulin
- insulin
- peroral use
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
- 102000004877 Insulin Human genes 0.000 title abstract 3
- 108090001061 Insulin Proteins 0.000 title abstract 3
- 229940125396 insulin Drugs 0.000 title abstract 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000005865 ionizing radiation Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
- A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006132763/15A RU2316339C1 (ru) | 2006-09-13 | 2006-09-13 | Способ получения препарата инсулина для перорального применения |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA93254C2 true UA93254C2 (ru) | 2011-01-25 |
Family
ID=39184228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200900222A UA93254C2 (ru) | 2006-09-13 | 2007-11-09 | Способ получения препарата инсулина для перорального применения |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20090312235A1 (ru) |
| EP (1) | EP2067484A4 (ru) |
| JP (1) | JP2010503665A (ru) |
| CN (1) | CN101384276A (ru) |
| AU (1) | AU2007295132A1 (ru) |
| CA (1) | CA2662799A1 (ru) |
| EA (1) | EA012884B1 (ru) |
| IL (1) | IL197470A0 (ru) |
| MX (1) | MX2009001286A (ru) |
| RU (1) | RU2316339C1 (ru) |
| UA (1) | UA93254C2 (ru) |
| WO (1) | WO2008033058A2 (ru) |
| ZA (1) | ZA200807272B (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA90013C2 (ru) | 2008-03-19 | 2010-03-25 | Давид Анатолійович Нога | Фармацевтическая композиция, содержащая инсулин, и способ его получения |
| RU2395296C1 (ru) * | 2009-02-19 | 2010-07-27 | Общество С Ограниченной Ответственностью "Концерн О3" | Способ получения препарата проинсулина для перорального применения |
| RU2413531C2 (ru) * | 2009-03-31 | 2011-03-10 | Общество С Ограниченной Ответственностью "Концерн О3" | Способ получения препарата с-пептида проинсулина для перорального применения |
| RU2441036C1 (ru) * | 2010-09-30 | 2012-01-27 | Общество с ограниченной ответственностью Научно-производственное объединение "Перспектива" (ООО НПО "Перспектива") | Способ получения активированного полиэтиленоксида |
| RU2452509C1 (ru) * | 2011-01-31 | 2012-06-10 | Общество с ограниченной ответственностью "Саентифик Фьючер Менеджмент" ООО "Саентифик Фьючер Менеджмент" | Средство для стимуляции роста организма |
| CN107007608B (zh) * | 2011-12-12 | 2021-04-23 | 梅里奥尔医药I公司 | I型和ii型糖尿病的治疗 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2066551C1 (ru) * | 1994-03-23 | 1996-09-20 | Институт нефтехимического синтеза РАН | Способ получения инсулинсодержащих полимерных гидрогелей |
| RU2117488C1 (ru) * | 1997-07-30 | 1998-08-20 | Институт нефтехимического синтеза им.А.В.Топчиева РАН | Твердое инсулинсодержащее лекарственное средство |
| RU2213557C2 (ru) * | 2001-12-26 | 2003-10-10 | Закрытое акционерное общество "Аксис" | Фармацевтическая композиция, обладающая тромболитическими, противовоспалительными и цитопротективными свойствами |
-
2006
- 2006-09-13 RU RU2006132763/15A patent/RU2316339C1/ru active IP Right Revival
-
2007
- 2007-09-11 MX MX2009001286A patent/MX2009001286A/es unknown
- 2007-09-11 AU AU2007295132A patent/AU2007295132A1/en not_active Abandoned
- 2007-09-11 EA EA200801259A patent/EA012884B1/ru not_active IP Right Cessation
- 2007-09-11 WO PCT/RU2007/000483 patent/WO2008033058A2/ru not_active Ceased
- 2007-09-11 JP JP2009528195A patent/JP2010503665A/ja not_active Withdrawn
- 2007-09-11 CN CNA2007800060392A patent/CN101384276A/zh active Pending
- 2007-09-11 EP EP07834992A patent/EP2067484A4/de not_active Withdrawn
- 2007-09-11 US US12/310,892 patent/US20090312235A1/en not_active Abandoned
- 2007-09-11 CA CA002662799A patent/CA2662799A1/en not_active Abandoned
- 2007-11-09 UA UAA200900222A patent/UA93254C2/ru unknown
-
2008
- 2008-08-22 ZA ZA200807272A patent/ZA200807272B/xx unknown
-
2009
- 2009-03-08 IL IL197470A patent/IL197470A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101384276A (zh) | 2009-03-11 |
| ZA200807272B (en) | 2009-07-29 |
| WO2008033058A3 (en) | 2008-05-08 |
| MX2009001286A (es) | 2009-03-20 |
| CA2662799A1 (en) | 2008-03-20 |
| JP2010503665A (ja) | 2010-02-04 |
| RU2316339C1 (ru) | 2008-02-10 |
| IL197470A0 (en) | 2011-08-01 |
| EA012884B1 (ru) | 2009-12-30 |
| EA200801259A1 (ru) | 2008-08-29 |
| EP2067484A4 (de) | 2009-10-28 |
| EP2067484A2 (de) | 2009-06-10 |
| AU2007295132A1 (en) | 2008-03-20 |
| WO2008033058A2 (en) | 2008-03-20 |
| US20090312235A1 (en) | 2009-12-17 |
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