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UA88018C2 - Potassium channel inhibitors - Google Patents

Potassium channel inhibitors

Info

Publication number
UA88018C2
UA88018C2 UAA200702125A UAA200702125A UA88018C2 UA 88018 C2 UA88018 C2 UA 88018C2 UA A200702125 A UAA200702125 A UA A200702125A UA A200702125 A UAA200702125 A UA A200702125A UA 88018 C2 UA88018 C2 UA 88018C2
Authority
UA
Ukraine
Prior art keywords
potassium channel
channel inhibitors
inhibitors
compounds
useful
Prior art date
Application number
UAA200702125A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Марк Т. БИЛОДО
Чжицай У
Джон Хартнетт
Original Assignee
Мерк Энд Ко., Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мерк Энд Ко., Инк. filed Critical Мерк Энд Ко., Инк.
Publication of UA88018C2 publication Critical patent/UA88018C2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to compounds having the structure Formula (I) useful as potassium channel inhibitors to treat cardiac arrhythmias.
UAA200702125A 2004-07-29 2005-07-25 Potassium channel inhibitors UA88018C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59218104P 2004-07-29 2004-07-29

Publications (1)

Publication Number Publication Date
UA88018C2 true UA88018C2 (en) 2009-09-10

Family

ID=35613661

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200702125A UA88018C2 (en) 2004-07-29 2005-07-25 Potassium channel inhibitors

Country Status (15)

Country Link
KR (1) KR20070043985A (en)
AR (1) AR049847A1 (en)
BR (1) BRPI0513793A (en)
CR (1) CR8876A (en)
EC (1) ECSP077208A (en)
IL (1) IL180846A0 (en)
MA (1) MA28980B1 (en)
MX (1) MX2007001188A (en)
NO (1) NO20071107L (en)
PE (1) PE20060382A1 (en)
RU (1) RU2344134C2 (en)
TW (1) TW200607493A (en)
UA (1) UA88018C2 (en)
WO (1) WO2006028590A1 (en)
ZA (1) ZA200700477B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010225405B2 (en) * 2009-03-18 2014-10-23 Medicure International Inc. Transdermal pharmaceutical preparation and administration of tirofiban
CA2876359C (en) 2012-06-11 2020-01-21 Bristol-Myers Squibb Company Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino) quinazolin-2-yl] pyridine-3-sulfonamide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2140865B2 (en) * 1971-08-14 1979-10-11 Bayer Ag, 5090 Leverkusen 1-imidazolyl-methanephosphonic acid ester, process for their preparation and medicaments containing them
DE19951701A1 (en) * 1999-10-27 2001-05-03 Aventis Pharma Gmbh Use of 2-imidazolyl-substituted carbinols for the manufacture of a medicament for the treatment or prophylaxis of diseases caused by ischemic conditions
EP2292595A1 (en) * 2002-01-04 2011-03-09 NeuroSearch AS Potassium channel modulators

Also Published As

Publication number Publication date
TW200607493A (en) 2006-03-01
PE20060382A1 (en) 2006-05-15
KR20070043985A (en) 2007-04-26
CR8876A (en) 2007-08-28
WO2006028590A1 (en) 2006-03-16
RU2344134C2 (en) 2009-01-20
AR049847A1 (en) 2006-09-06
MA28980B1 (en) 2007-11-01
MX2007001188A (en) 2007-03-21
NO20071107L (en) 2007-04-19
BRPI0513793A (en) 2008-05-13
ECSP077208A (en) 2007-02-28
IL180846A0 (en) 2007-06-03
RU2007107408A (en) 2008-09-10
ZA200700477B (en) 2009-08-26

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