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NO20071107L - 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri (hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors - Google Patents

1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri (hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors

Info

Publication number
NO20071107L
NO20071107L NO20071107A NO20071107A NO20071107L NO 20071107 L NO20071107 L NO 20071107L NO 20071107 A NO20071107 A NO 20071107A NO 20071107 A NO20071107 A NO 20071107A NO 20071107 L NO20071107 L NO 20071107L
Authority
NO
Norway
Prior art keywords
hetero
heterocyclylethanes
arylethanes
tetra
tri
Prior art date
Application number
NO20071107A
Other languages
Norwegian (no)
Inventor
Mark T Bilodeau
Zhicai Wu
John Hartnett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO20071107L publication Critical patent/NO20071107L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Foreliggende oppfinnelse angår forbindelser som har strukturen av formel (I) som er anvendbare som kaliumkanalinhibitorer for behandling av hjertearytmier.The present invention relates to compounds having the structure of formula (I) useful as potassium channel inhibitors for the treatment of cardiac arrhythmias.

NO20071107A 2004-07-29 2007-02-27 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri (hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors NO20071107L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59218104P 2004-07-29 2004-07-29
PCT/US2005/026334 WO2006028590A1 (en) 2004-07-29 2005-07-25 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri (hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors

Publications (1)

Publication Number Publication Date
NO20071107L true NO20071107L (en) 2007-04-19

Family

ID=35613661

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071107A NO20071107L (en) 2004-07-29 2007-02-27 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri (hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors

Country Status (15)

Country Link
KR (1) KR20070043985A (en)
AR (1) AR049847A1 (en)
BR (1) BRPI0513793A (en)
CR (1) CR8876A (en)
EC (1) ECSP077208A (en)
IL (1) IL180846A0 (en)
MA (1) MA28980B1 (en)
MX (1) MX2007001188A (en)
NO (1) NO20071107L (en)
PE (1) PE20060382A1 (en)
RU (1) RU2344134C2 (en)
TW (1) TW200607493A (en)
UA (1) UA88018C2 (en)
WO (1) WO2006028590A1 (en)
ZA (1) ZA200700477B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120029447A1 (en) * 2009-03-18 2012-02-02 Medicure International Inc. Transdermal pharmaceutical preparation and administration of tirofiban
HRP20180815T8 (en) 2012-06-11 2019-02-08 Bristol-Myers Squibb Company 5- [5-Phenyl-4- (pyridin-2-ylmethylamino) quinazolin-2-yl] pyridine-3-sulfonamide PHOSPHORAMIDE ACID PRODUCTS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2140865B2 (en) * 1971-08-14 1979-10-11 Bayer Ag, 5090 Leverkusen 1-imidazolyl-methanephosphonic acid ester, process for their preparation and medicaments containing them
DE19951701A1 (en) * 1999-10-27 2001-05-03 Aventis Pharma Gmbh Use of 2-imidazolyl-substituted carbinols for the manufacture of a medicament for the treatment or prophylaxis of diseases caused by ischemic conditions
ATE400551T1 (en) * 2002-01-04 2008-07-15 Neurosearch As POTASSIUM CHANNEL MODULATORS

Also Published As

Publication number Publication date
IL180846A0 (en) 2007-06-03
RU2344134C2 (en) 2009-01-20
TW200607493A (en) 2006-03-01
PE20060382A1 (en) 2006-05-15
ECSP077208A (en) 2007-02-28
KR20070043985A (en) 2007-04-26
BRPI0513793A (en) 2008-05-13
RU2007107408A (en) 2008-09-10
AR049847A1 (en) 2006-09-06
CR8876A (en) 2007-08-28
ZA200700477B (en) 2009-08-26
MX2007001188A (en) 2007-03-21
WO2006028590A1 (en) 2006-03-16
UA88018C2 (en) 2009-09-10
MA28980B1 (en) 2007-11-01

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application