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Application filed by Институт Органической Химии Нан УкраиныfiledCriticalИнститут Органической Химии Нан Украины
Priority to UAA200713679ApriorityCriticalpatent/UA84821C2/en
Publication of UA84821C2publicationCriticalpatent/UA84821C2/en
The invention relates to a process for the preparation of chiral 4-amino-4-aryl-5,5,5-trifluoropentane-2-ones of general formula I:, Іwherein Аr = Ph, 4-FCH, 3-MeCH, 4-MeCH, 4-МеОСН,which consists in that aryltrifluoromethyl ketimines are subjected to interaction with acetone in dimethyl sulfoxide solution at room temperature in the presence of 10-% catalytic amount of L- or D-proline followed by isolation of desired products by conventional methods.
UAA200713679A2007-12-072007-12-07Process for the preparation of chiral 4-amino-4-aryl-5,5,5-trifluoropentane-2-ones
UA84821C2
(en)