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UA82853C2 - Carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof - Google Patents

Carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof Download PDF

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Publication number
UA82853C2
UA82853C2 UAA200502601A UA2005002601A UA82853C2 UA 82853 C2 UA82853 C2 UA 82853C2 UA A200502601 A UAA200502601 A UA A200502601A UA 2005002601 A UA2005002601 A UA 2005002601A UA 82853 C2 UA82853 C2 UA 82853C2
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UA
Ukraine
Prior art keywords
group
phenyl
pyrrolidin
carboxylic acid
ylmethylphenyl
Prior art date
Application number
UAA200502601A
Other languages
English (en)
Ukrainian (uk)
Inventor
Thorsten Lehmann-Lintz
Dirk Stenkamp
Martin Lenter
Klaus Rudolf
Stefan Georg Muller
Kirsten Arndt
Philipp Lustenberger
Original Assignee
Boehringer Ingelheim Pharma
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Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UA82853C2 publication Critical patent/UA82853C2/uk

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    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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UAA200502601A 2002-08-24 2003-08-16 Carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof UA82853C2 (en)

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CA2496563A1 (en) 2004-03-25
CN1678591A (zh) 2005-10-05
PE20040974A1 (es) 2005-01-12
RS20050173A (sr) 2007-09-21
DE10238865A1 (de) 2004-03-11
BR0313790A (pt) 2005-07-12
AU2003258620A1 (en) 2004-04-30
MXPA05002158A (es) 2005-05-23

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