UA42739C2 - Method of inhibition of the photodisintegration of pharmaceutical active compounds, tablet and capsule, containing thereof - Google Patents
Method of inhibition of the photodisintegration of pharmaceutical active compounds, tablet and capsule, containing thereofInfo
- Publication number
- UA42739C2 UA42739C2 UA96041574A UA96041574A UA42739C2 UA 42739 C2 UA42739 C2 UA 42739C2 UA 96041574 A UA96041574 A UA 96041574A UA 96041574 A UA96041574 A UA 96041574A UA 42739 C2 UA42739 C2 UA 42739C2
- Authority
- UA
- Ukraine
- Prior art keywords
- dye
- photodisintegration
- capsule
- inhibition
- tablet
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polymerisation Methods In General (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Abstract
Спосіб інгібування фоторозпаду фармацевтично активної сполуки передбачає використання сполуки формули: та її енольної форми чи її фармацевтично прийнятної основної солі, де Х - Н, CI чи F; Y - Н чи CI; R - бензил чи тієніл, кожний необов’язково заміщений CI чи F. У якості засобу, що поглинає світло, використовують барвник, що вибрано з групи, що складається з жовтого барвника N 6, червоного барвника N 40, червоного барвника N 3, жовтого пігменту N 6, червоного пігменту N 40 та червоного пігменту N 3 чи пакувальний матеріал, що ефективний у поглинанні світла.A method of inhibiting the photodegradation of a pharmaceutically active compound involves the use of a compound of formula: and its enol form or a pharmaceutically acceptable base salt thereof, wherein X is H, CI or F; Y - H or CI; R is benzyl or thienyl, each optionally substituted with CI or F. As the light absorbing agent, a dye selected from the group consisting of yellow dye No. 6, red dye No. 40, red dye No. 3, yellow is used. pigment No. 6, red pigment No. 40 and red pigment No. 3 or packaging material that is effective in absorbing light.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB1995/000287 WO1996033701A1 (en) | 1995-04-24 | 1995-04-24 | Inhibiting photodecomposition of 3-substituted-2-oxindoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA42739C2 true UA42739C2 (en) | 2001-11-15 |
Family
ID=36997502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA96041574A UA42739C2 (en) | 1995-04-24 | 1995-04-24 | Method of inhibition of the photodisintegration of pharmaceutical active compounds, tablet and capsule, containing thereof |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0827399A1 (en) |
| JP (1) | JPH10506635A (en) |
| KR (1) | KR100189585B1 (en) |
| CN (1) | CN1053667C (en) |
| AP (1) | AP607A (en) |
| AR (1) | AR002728A1 (en) |
| AU (1) | AU692378B2 (en) |
| BG (1) | BG100531A (en) |
| BR (1) | BR9602024A (en) |
| CO (1) | CO4700418A1 (en) |
| FI (1) | FI973988A0 (en) |
| HR (1) | HRP960194A2 (en) |
| HU (1) | HU216544B (en) |
| IL (1) | IL117969A0 (en) |
| IS (1) | IS4339A (en) |
| MA (1) | MA23848A1 (en) |
| NO (1) | NO961622L (en) |
| NZ (1) | NZ286432A (en) |
| OA (1) | OA10286A (en) |
| PE (1) | PE34397A1 (en) |
| RO (1) | RO113305B1 (en) |
| RU (1) | RU2109510C1 (en) |
| SG (1) | SG64924A1 (en) |
| SI (1) | SI9600133A (en) |
| SK (1) | SK51296A3 (en) |
| TR (1) | TR199600300A2 (en) |
| UA (1) | UA42739C2 (en) |
| WO (1) | WO1996033701A1 (en) |
| YU (1) | YU25096A (en) |
| ZA (1) | ZA963210B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2758128C1 (en) | 2017-12-29 | 2021-10-26 | Крафт Фудс Груп Брэндс Ллк | Improved oxidation stability of oil-in-water emulsions using natural stabilisers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3136282A1 (en) * | 1981-09-12 | 1983-03-24 | Hoechst Ag | "METHOD FOR STABILIZING PHOTO-UNSTABLE MEDICINAL PRODUCTS AND STABILIZED MEDICAL PREPARATIONS" |
| HUT59592A (en) * | 1990-07-20 | 1992-06-29 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of solid medical products |
| TW438798B (en) * | 1992-10-07 | 2001-06-07 | Pfizer | 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions |
-
1995
- 1995-04-24 EP EP95914494A patent/EP0827399A1/en not_active Ceased
- 1995-04-24 RU RU96108120A patent/RU2109510C1/en active
- 1995-04-24 FI FI973988A patent/FI973988A0/en unknown
- 1995-04-24 WO PCT/IB1995/000287 patent/WO1996033701A1/en not_active Ceased
- 1995-04-24 UA UA96041574A patent/UA42739C2/en unknown
- 1995-04-24 SK SK512-96A patent/SK51296A3/en unknown
- 1995-04-24 JP JP8532298A patent/JPH10506635A/en active Pending
-
1996
- 1996-03-07 AP APAP/P/1996/000787A patent/AP607A/en active
- 1996-03-28 AR ARP960101956A patent/AR002728A1/en unknown
- 1996-04-10 TR TR96/00300A patent/TR199600300A2/en unknown
- 1996-04-18 IL IL11796996A patent/IL117969A0/en unknown
- 1996-04-19 IS IS4339A patent/IS4339A/en unknown
- 1996-04-19 SG SG1996009306A patent/SG64924A1/en unknown
- 1996-04-22 PE PE1996000275A patent/PE34397A1/en not_active Application Discontinuation
- 1996-04-22 CN CN96105084A patent/CN1053667C/en not_active Expired - Fee Related
- 1996-04-22 CO CO96019210A patent/CO4700418A1/en unknown
- 1996-04-22 RO RO96-00843A patent/RO113305B1/en unknown
- 1996-04-23 HU HU9601057A patent/HU216544B/en not_active IP Right Cessation
- 1996-04-23 BG BG100531A patent/BG100531A/en unknown
- 1996-04-23 NO NO961622A patent/NO961622L/en unknown
- 1996-04-23 NZ NZ286432A patent/NZ286432A/en unknown
- 1996-04-23 MA MA24209A patent/MA23848A1/en unknown
- 1996-04-23 YU YU25096A patent/YU25096A/en unknown
- 1996-04-23 HR HRPCT/IB95/00287A patent/HRP960194A2/en not_active Application Discontinuation
- 1996-04-23 ZA ZA9603210A patent/ZA963210B/en unknown
- 1996-04-23 AU AU50851/96A patent/AU692378B2/en not_active Ceased
- 1996-04-23 KR KR1019960012356A patent/KR100189585B1/en not_active Expired - Fee Related
- 1996-04-24 OA OA60821A patent/OA10286A/en unknown
- 1996-04-24 BR BR9602024A patent/BR9602024A/en active Search and Examination
- 1996-04-24 SI SI9600133A patent/SI9600133A/en not_active IP Right Cessation
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