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UA42739C2 - Спосіб інгібування фоторозкладу фармацевтично активних сполук, таблетка та капсула, що їх містять - Google Patents

Спосіб інгібування фоторозкладу фармацевтично активних сполук, таблетка та капсула, що їх містять

Info

Publication number
UA42739C2
UA42739C2 UA96041574A UA96041574A UA42739C2 UA 42739 C2 UA42739 C2 UA 42739C2 UA 96041574 A UA96041574 A UA 96041574A UA 96041574 A UA96041574 A UA 96041574A UA 42739 C2 UA42739 C2 UA 42739C2
Authority
UA
Ukraine
Prior art keywords
dye
photodisintegration
capsule
inhibition
tablet
Prior art date
Application number
UA96041574A
Other languages
English (en)
Russian (ru)
Inventor
Віллард мол. Ньюлін
Виллард мл. Ньюлин
Шарон М. Лафлін
Шарон М. ЛАФЛИН
Original Assignee
Пфайзер Інк.
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Інк., Пфайзер Инк. filed Critical Пфайзер Інк.
Publication of UA42739C2 publication Critical patent/UA42739C2/uk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4883Capsule finishing, e.g. dyeing, aromatising, polishing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polymerisation Methods In General (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

Спосіб інгібування фоторозпаду фармацевтично активної сполуки передбачає використання сполуки формули: та її енольної форми чи її фармацевтично прийнятної основної солі, де Х - Н, CI чи F; Y - Н чи CI; R - бензил чи тієніл, кожний необов’язково заміщений CI чи F. У якості засобу, що поглинає світло, використовують барвник, що вибрано з групи, що складається з жовтого барвника N 6, червоного барвника N 40, червоного барвника N 3, жовтого пігменту N 6, червоного пігменту N 40 та червоного пігменту N 3 чи пакувальний матеріал, що ефективний у поглинанні світла.
UA96041574A 1995-04-24 1995-04-24 Спосіб інгібування фоторозкладу фармацевтично активних сполук, таблетка та капсула, що їх містять UA42739C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB1995/000287 WO1996033701A1 (en) 1995-04-24 1995-04-24 Inhibiting photodecomposition of 3-substituted-2-oxindoles

Publications (1)

Publication Number Publication Date
UA42739C2 true UA42739C2 (uk) 2001-11-15

Family

ID=36997502

Family Applications (1)

Application Number Title Priority Date Filing Date
UA96041574A UA42739C2 (uk) 1995-04-24 1995-04-24 Спосіб інгібування фоторозкладу фармацевтично активних сполук, таблетка та капсула, що їх містять

Country Status (30)

Country Link
EP (1) EP0827399A1 (uk)
JP (1) JPH10506635A (uk)
KR (1) KR100189585B1 (uk)
CN (1) CN1053667C (uk)
AP (1) AP607A (uk)
AR (1) AR002728A1 (uk)
AU (1) AU692378B2 (uk)
BG (1) BG100531A (uk)
BR (1) BR9602024A (uk)
CO (1) CO4700418A1 (uk)
FI (1) FI973988A0 (uk)
HR (1) HRP960194A2 (uk)
HU (1) HU216544B (uk)
IL (1) IL117969A0 (uk)
IS (1) IS4339A (uk)
MA (1) MA23848A1 (uk)
NO (1) NO961622L (uk)
NZ (1) NZ286432A (uk)
OA (1) OA10286A (uk)
PE (1) PE34397A1 (uk)
RO (1) RO113305B1 (uk)
RU (1) RU2109510C1 (uk)
SG (1) SG64924A1 (uk)
SI (1) SI9600133A (uk)
SK (1) SK51296A3 (uk)
TR (1) TR199600300A2 (uk)
UA (1) UA42739C2 (uk)
WO (1) WO1996033701A1 (uk)
YU (1) YU25096A (uk)
ZA (1) ZA963210B (uk)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2758128C1 (ru) 2017-12-29 2021-10-26 Крафт Фудс Груп Брэндс Ллк Улучшенная устойчивость к окислению эмульсий типа "масло в воде" при помощи натуральных стабилизаторов

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3136282A1 (de) * 1981-09-12 1983-03-24 Hoechst Ag "verfahren zur stabilisierung photoinstabiler arzneistoffe sowie stabilisierte arzneizubereitungen"
HUT59592A (en) * 1990-07-20 1992-06-29 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of solid medical products
TW438798B (en) * 1992-10-07 2001-06-07 Pfizer 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions

Also Published As

Publication number Publication date
WO1996033701A1 (en) 1996-10-31
BG100531A (bg) 1997-06-30
HUP9601057A2 (en) 1997-04-28
AP9600787A0 (en) 1996-04-30
SK51296A3 (en) 1997-04-09
KR960037656A (ko) 1996-11-19
IS4339A (is) 1996-10-25
FI973988A7 (fi) 1997-10-17
HU9601057D0 (en) 1996-06-28
NO961622L (no) 1996-10-25
RU2109510C1 (ru) 1998-04-27
AU5085196A (en) 1996-11-07
EP0827399A1 (en) 1998-03-11
SG64924A1 (en) 1999-05-25
HU216544B (hu) 1999-07-28
HRP960194A2 (en) 1998-02-28
TR199600300A2 (tr) 1996-11-21
CN1053667C (zh) 2000-06-21
BR9602024A (pt) 1998-10-06
ZA963210B (en) 1997-10-23
PE34397A1 (es) 1997-09-29
HUP9601057A3 (en) 1997-05-28
AR002728A1 (es) 1998-04-29
FI973988L (fi) 1997-10-17
CN1139110A (zh) 1997-01-01
CO4700418A1 (es) 1998-12-29
KR100189585B1 (ko) 1999-06-01
NO961622D0 (no) 1996-04-23
MA23848A1 (fr) 1996-12-31
YU25096A (sh) 1998-08-14
IL117969A0 (en) 1996-08-04
JPH10506635A (ja) 1998-06-30
NZ286432A (en) 1998-05-27
RO113305B1 (ro) 1998-06-30
SI9600133A (en) 1996-10-31
AP607A (en) 1997-08-27
OA10286A (en) 1997-09-19
AU692378B2 (en) 1998-06-04
FI973988A0 (fi) 1997-10-17

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