UA19808A - Спосіб одержаhhя феhілалкіламіhів або солей цих сполук - Google Patents
Спосіб одержаhhя феhілалкіламіhів або солей цих сполукInfo
- Publication number
- UA19808A UA19808A UA4830945A UA4830945A UA19808A UA 19808 A UA19808 A UA 19808A UA 4830945 A UA4830945 A UA 4830945A UA 4830945 A UA4830945 A UA 4830945A UA 19808 A UA19808 A UA 19808A
- Authority
- UA
- Ukraine
- Prior art keywords
- phenylalkylamines
- starwriterprocess
- salts
- obtaining
- inhibiting
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000035 biogenic effect Effects 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- External Artificial Organs (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Цей винахід належить до органічного синтезу і стосується одержання фенілалкіламінів, що володіють біологічною активністю. Вони використовуються як активнодіюча речовина у фармацевтичних препаратах, стимулюючих центральну нервову систему. Ці сполуки виявляють свою дію на організм, головним чином, за рахунок інгібування нейронного поглинання біогенних амінів.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU864101A HU207280B (en) | 1986-09-25 | 1986-09-25 | Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA19808A true UA19808A (uk) | 1997-12-25 |
Family
ID=10966901
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA4742460A UA19171A (uk) | 1986-09-25 | 1987-09-25 | Спосіб одержаhhя фіhілалкіламіhів або їх фармакологічhо прийhятhих солей |
| UA4355858A UA11100A (uk) | 1986-09-25 | 1987-09-25 | Спосіб одержаhhя феhілалкіламіhів або їх фармакологічhо прийhятhих солей |
| UA4830945A UA19808A (uk) | 1986-09-25 | 1990-09-10 | Спосіб одержаhhя феhілалкіламіhів або солей цих сполук |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA4742460A UA19171A (uk) | 1986-09-25 | 1987-09-25 | Спосіб одержаhhя фіhілалкіламіhів або їх фармакологічhо прийhятhих солей |
| UA4355858A UA11100A (uk) | 1986-09-25 | 1987-09-25 | Спосіб одержаhhя феhілалкіламіhів або їх фармакологічhо прийhятhих солей |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5075338A (uk) |
| EP (1) | EP0284621B1 (uk) |
| KR (1) | KR880701545A (uk) |
| AT (1) | ATE117204T1 (uk) |
| CS (1) | CS277418B6 (uk) |
| DD (1) | DD262226A5 (uk) |
| DE (1) | DE3751006T2 (uk) |
| DK (1) | DK282488D0 (uk) |
| ES (1) | ES2007411A6 (uk) |
| FI (1) | FI882474A0 (uk) |
| GE (1) | GEP19960656B (uk) |
| HU (1) | HU207280B (uk) |
| IL (1) | IL83905A (uk) |
| LT (2) | LT3530B (uk) |
| LV (2) | LV10860B (uk) |
| PL (1) | PL151642B1 (uk) |
| PT (1) | PT85799B (uk) |
| RU (1) | RU2007384C1 (uk) |
| SU (1) | SU1746882A3 (uk) |
| UA (3) | UA19171A (uk) |
| WO (1) | WO1988002254A1 (uk) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5430044A (en) * | 1987-02-06 | 1995-07-04 | Fisons Corporation | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties |
| ES2083972T3 (es) * | 1988-08-12 | 1996-05-01 | Astra Ab | Arilalquil-aminas y -amidas con propiedades anticonvulsivas y neuroprotectoras. |
| AU641394B2 (en) * | 1989-06-02 | 1993-09-23 | John Wyeth & Brother Limited | Amines |
| US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| HUT63579A (en) * | 1991-12-20 | 1993-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes |
| HU228150B1 (en) | 1994-10-21 | 2012-12-28 | Nps Pharma Inc | Calcium receptor-active compounds, medicaments comprising them, and the use of said medicaments |
| US6033682A (en) | 1995-01-13 | 2000-03-07 | Somerset Pharmaceuticals, Inc. | S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions |
| US6348208B1 (en) | 1995-01-13 | 2002-02-19 | Somerset Pharmaceuticals, Inc. | Methods and pharmaceutical compositions employing desmethylselegiline |
| US6299901B1 (en) | 1995-01-13 | 2001-10-09 | Somerset Pharmaceuticals, Inc. | Methods and pharmaceutical compositions employing desmethylselegiline |
| US6319954B1 (en) | 1995-01-13 | 2001-11-20 | Somerset Pharmaceuticals, Inc. | S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions |
| US6316022B1 (en) | 1995-06-07 | 2001-11-13 | Noven Pharmaceuticals, Inc. | Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures |
| CA2223588C (en) * | 1995-06-07 | 2004-01-06 | Noven Pharmaceuticals, Inc. | Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures |
| EP0907631B1 (en) * | 1996-05-01 | 2003-06-18 | Nps Pharmaceuticals, Inc. | Inorganic ion receptor-active compounds |
| CA2267315C (en) * | 1997-08-07 | 2008-01-08 | Fujimoto Brothers Co., Ltd. | Ethylamine derivatives |
| JP4499208B2 (ja) * | 1998-10-29 | 2010-07-07 | 株式会社フジモト・コーポレーション | 新規な光学活性アミノペンタン誘導体 |
| US20030119884A1 (en) * | 2000-11-01 | 2003-06-26 | Epstein Mel H. | Methods and compositions for regulating memory consolidation |
| EP1420768A2 (en) * | 2000-11-01 | 2004-05-26 | Sention, Inc. | Methods and compositions for regulating memory consolidation |
| US20030232890A1 (en) * | 2000-11-01 | 2003-12-18 | Sention, Inc. | Methods for treating an impairment in memory consolidation |
| US20050059743A1 (en) * | 2000-11-01 | 2005-03-17 | Sention, Inc. | Methods for treating mild cognitive impairment and alzheimer's disease |
| US20070117869A1 (en) * | 2000-11-01 | 2007-05-24 | Cognition Pharmaceuticals Llc | Methods for treating coginitive impairment and improving cognition |
| US7619005B2 (en) * | 2000-11-01 | 2009-11-17 | Cognition Pharmaceuticals Llc | Methods for treating cognitive impairment in humans with Multiple Sclerosis |
| WO2005000203A2 (en) | 2001-10-31 | 2005-01-06 | Sention, Inc. | Methods for treating cognitive impairment and improving cognition |
| CA2446074C (en) * | 2001-05-02 | 2011-09-06 | Blanchette Rockefeller Neurosciences Institute | Carbonic anhydrase activators for enhancing learning and memory |
| EP1935414A3 (en) * | 2001-05-02 | 2010-08-18 | Blanchette Rockefeller Neurosciences Institute | Carbonic anhydrase activators for enhancig learning and memory |
| TW201206425A (en) | 2004-05-18 | 2012-02-16 | Brni Neurosciences Inst | Treatment of depressive disorders |
| EP2419400A1 (en) | 2009-04-15 | 2012-02-22 | Research Triangle Institute | Monoamine reuptake inhibitors |
| CA2968806A1 (en) | 2014-12-05 | 2016-06-09 | Semmelweis University | Use of arylalkylamine monoamine oxidase inhibitors in the treatment or prevention of cancer |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US485926A (en) | 1892-11-08 | Field | ||
| DE767263C (de) * | 1937-10-03 | 1952-03-31 | Theodor H Temmler | Verfahren zur Herstellung von ª-Aralkylaminen |
| DE893341C (de) * | 1950-08-23 | 1953-10-15 | Troponwerke Dinklage & Co | Verfahren zur Herstellung von N-Aralkyl-ª-phenyl-isopropylaminen |
| US2797242A (en) * | 1953-08-11 | 1957-06-25 | Parke Davis & Co | Substituted alpha-benzylphenethylamines and methods for producing the same |
| DE227447C (uk) | 1955-03-23 | 1910-10-21 | ||
| DE1210873B (de) * | 1959-03-18 | 1966-02-17 | Hoffmann La Roche | Verfahren zur Herstellung von Halogenalkylaminen |
| US3044932A (en) * | 1960-02-24 | 1962-07-17 | Upjohn Co | Appetite suppressant drugs |
| DE1133395B (de) * | 1960-11-12 | 1962-07-19 | Hoechst Ag | Verfahren zur Herstellung von herz- und kreislaufwirksamen Phenylalkylaminen |
| GB1031425A (en) * | 1962-03-30 | 1966-06-02 | Chinoin Gyogyszer Es Vegyeszet | New aralkylamines and their preparation |
| DE1227447B (de) * | 1962-03-30 | 1966-10-27 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von Phenylisopropylaminen |
| FR1478311A (fr) * | 1963-10-18 | 1967-04-28 | Koninklijke Pharma Fab Nv | Procédé de préparation d'aminoalcanes et produits en résultant |
| GB1218135A (en) * | 1967-07-28 | 1971-01-06 | Abbott Lab | Substituted phenethylamine derivatives |
| DE2143204C3 (de) * | 1971-08-28 | 1979-09-27 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis |
| US4025624A (en) * | 1975-11-18 | 1977-05-24 | A. H. Robins Company, Incorporated | Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy |
| US4404222A (en) * | 1980-08-25 | 1983-09-13 | American Cyanamid Company | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby |
| DD145599A1 (de) * | 1979-08-23 | 1980-12-24 | Roswitha Toepfer | Mittel zur regulierung des pflanzenwachstums |
-
1986
- 1986-09-25 HU HU864101A patent/HU207280B/hu not_active IP Right Cessation
-
1987
- 1987-09-15 IL IL83905A patent/IL83905A/xx not_active IP Right Cessation
- 1987-09-21 DD DD87307094A patent/DD262226A5/de not_active IP Right Cessation
- 1987-09-23 ES ES8702717A patent/ES2007411A6/es not_active Expired
- 1987-09-25 UA UA4742460A patent/UA19171A/uk unknown
- 1987-09-25 AT AT87906316T patent/ATE117204T1/de not_active IP Right Cessation
- 1987-09-25 PT PT85799A patent/PT85799B/pt not_active IP Right Cessation
- 1987-09-25 EP EP87906316A patent/EP0284621B1/en not_active Expired - Lifetime
- 1987-09-25 WO PCT/HU1987/000040 patent/WO1988002254A1/en not_active Ceased
- 1987-09-25 CS CS876898A patent/CS277418B6/cs unknown
- 1987-09-25 PL PL1987267913A patent/PL151642B1/pl unknown
- 1987-09-25 UA UA4355858A patent/UA11100A/uk unknown
- 1987-09-25 DE DE3751006T patent/DE3751006T2/de not_active Expired - Fee Related
-
1988
- 1988-05-24 KR KR1019880700574A patent/KR880701545A/ko not_active Ceased
- 1988-05-24 DK DK282488A patent/DK282488D0/da not_active Application Discontinuation
- 1988-05-24 SU SU884355858A patent/SU1746882A3/ru active
- 1988-05-25 FI FI882474A patent/FI882474A0/fi not_active IP Right Cessation
-
1989
- 1989-10-11 US US07/420,058 patent/US5075338A/en not_active Expired - Fee Related
- 1989-11-23 RU SU894742460A patent/RU2007384C1/ru active
-
1990
- 1990-09-10 UA UA4830945A patent/UA19808A/uk unknown
-
1993
- 1993-06-22 LV LVP-93-650A patent/LV10860B/lv unknown
- 1993-06-22 LV LVP-93-651A patent/LV10709B/lv unknown
- 1993-08-12 GE GEAP19931393A patent/GEP19960656B/en unknown
- 1993-08-19 LT LTIP878A patent/LT3530B/lt not_active IP Right Cessation
- 1993-08-19 LT LTIP879A patent/LT3531B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| LTIP879A (en) | 1995-03-27 |
| UA11100A (uk) | 1996-12-25 |
| CS277418B6 (en) | 1993-03-17 |
| PL151642B1 (en) | 1990-09-28 |
| LV10860A (lv) | 1995-10-20 |
| PT85799B (pt) | 1990-08-31 |
| UA19171A (uk) | 1997-12-25 |
| DK282488A (da) | 1988-05-24 |
| CS689887A3 (en) | 1992-08-12 |
| FI882474A7 (fi) | 1988-05-25 |
| EP0284621B1 (en) | 1995-01-18 |
| US5075338A (en) | 1991-12-24 |
| PT85799A (en) | 1987-10-01 |
| LT3531B (en) | 1995-11-27 |
| PL267913A1 (en) | 1989-03-06 |
| KR880701545A (ko) | 1988-11-03 |
| ES2007411A6 (es) | 1989-06-16 |
| WO1988002254A1 (en) | 1988-04-07 |
| LT3530B (en) | 1995-11-27 |
| DE3751006T2 (de) | 1995-05-24 |
| LV10709A (lv) | 1995-06-20 |
| LTIP878A (en) | 1995-03-27 |
| RU2007384C1 (ru) | 1994-02-15 |
| HU207280B (en) | 1993-03-29 |
| DK282488D0 (da) | 1988-05-24 |
| HUT45962A (en) | 1988-09-28 |
| GEP19960656B (en) | 1996-12-24 |
| IL83905A (en) | 1993-07-08 |
| FI882474A0 (fi) | 1988-05-25 |
| DE3751006D1 (de) | 1995-03-02 |
| ATE117204T1 (de) | 1995-02-15 |
| DD262226A5 (de) | 1988-11-23 |
| SU1746882A3 (ru) | 1992-07-07 |
| LV10709B (en) | 1995-12-20 |
| EP0284621A1 (en) | 1988-10-05 |
| LV10860B (en) | 1996-04-20 |
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