UA107457C2 - Похідні піразолу - Google Patents
Похідні піразолуInfo
- Publication number
- UA107457C2 UA107457C2 UAA201112488A UAA201112488A UA107457C2 UA 107457 C2 UA107457 C2 UA 107457C2 UA A201112488 A UAA201112488 A UA A201112488A UA A201112488 A UAA201112488 A UA A201112488A UA 107457 C2 UA107457 C2 UA 107457C2
- Authority
- UA
- Ukraine
- Prior art keywords
- hydrogen atom
- halogen atom
- substituent
- pyrazole derivatives
- atom
- Prior art date
Links
- 150000003217 pyrazoles Chemical class 0.000 title 1
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Винахід стосується сполуки, що більш сильно пригнічує секрецію кислоти та має противиразкову дію, тощо. Сполука, представлена формулою EMBED ISISServer , (I) де R1 є замісником, R2 означає (і) атом водню, (іі) С1-6-алкіл, який необов'язково містить атом галогену, або (ііі) ціаногрупу, R3 означає (і) атом водню, (іі) атом галогену, (ііі) ціаногрупу, (iv) С1-6-алкіл, який необов'язково містить атом галогену, або (v) С1-6-алкокси, який необов'язково містить атом галогену, один з R2 та R3 означає атом водню та інший є замісником, що не є атомом водню, або її сіль.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009077078 | 2009-03-26 | ||
| PCT/JP2010/055257 WO2010110378A1 (ja) | 2009-03-26 | 2010-03-25 | ピラゾール化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA107457C2 true UA107457C2 (uk) | 2015-01-12 |
Family
ID=42781069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201112488A UA107457C2 (uk) | 2009-03-26 | 2010-03-25 | Похідні піразолу |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8895588B2 (uk) |
| EP (1) | EP2412713B1 (uk) |
| JP (1) | JP5552481B2 (uk) |
| KR (1) | KR101656906B1 (uk) |
| CN (1) | CN102448953B (uk) |
| AU (1) | AU2010228220B2 (uk) |
| BR (1) | BRPI1009090A2 (uk) |
| CA (1) | CA2756086A1 (uk) |
| CL (1) | CL2011002351A1 (uk) |
| CO (1) | CO6460700A2 (uk) |
| CR (1) | CR20110533A (uk) |
| DO (1) | DOP2011000296A (uk) |
| EA (1) | EA019853B1 (uk) |
| EC (1) | ECSP11011419A (uk) |
| GE (1) | GEP20156222B (uk) |
| IL (1) | IL215235A (uk) |
| MA (1) | MA33214B1 (uk) |
| MX (1) | MX2011009943A (uk) |
| NZ (1) | NZ595890A (uk) |
| PE (1) | PE20120618A1 (uk) |
| SG (1) | SG174476A1 (uk) |
| TN (1) | TN2011000474A1 (uk) |
| UA (1) | UA107457C2 (uk) |
| WO (1) | WO2010110378A1 (uk) |
| ZA (1) | ZA201107435B (uk) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI623327B (zh) | 2012-06-27 | 2018-05-11 | 武田藥品工業股份有限公司 | 液狀製劑 |
| PL3524260T3 (pl) * | 2012-09-27 | 2023-11-27 | Elanco Animal Health Incorporated | Kompozycje farmaceutyczne do leczenia braku apetytu |
| BR112017016078A2 (pt) | 2015-01-28 | 2018-04-03 | Aratana Therapeutics Inc | composições e métodos para uso crônico de um composto de ganho de peso |
| CN105067814A (zh) * | 2015-07-24 | 2015-11-18 | 中国科学院成都生物研究所 | 解旋酶水解atp活性测定方法 |
| HUE070031T2 (hu) * | 2020-06-17 | 2025-05-28 | Ildong Pharmaceutical Co Ltd | Új savszekréciós inhibitor és alkalmazása |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3285991A (en) | 1963-03-26 | 1966-11-15 | Union Carbide Corp | Polyepoxides cured with the reaction product of a dihydroxydiphenylsul-fone, an amine, and an aldehyde |
| US4847289A (en) | 1987-06-08 | 1989-07-11 | Merck & Co., Inc. | Thiophene sulfonamide antiglaucoma agents |
| MX9205392A (es) | 1991-10-29 | 1993-04-01 | Du Pont | Triazolcarbozamidas herbicidas y procedimiento para su obtencion. |
| DK0786455T3 (da) | 1994-09-26 | 2004-03-29 | Shionogi & Co | Imidazolderivater |
| JPH0948778A (ja) | 1995-08-04 | 1997-02-18 | Sagami Chem Res Center | ２−置換−３−アルコキシ−５−（ピロール−２−イル）フラン誘導体 |
| CA2235986C (en) | 1995-11-06 | 2006-09-12 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| EP0946508B1 (en) | 1996-12-23 | 2009-09-23 | Bristol-Myers Squibb Pharma Company | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS |
| WO1999042461A1 (en) | 1998-02-23 | 1999-08-26 | Warner-Lambert Company | Substituted quinoxaline derivatives as interleukin-8 receptor antagonists |
| WO2004012659A2 (en) | 2002-08-01 | 2004-02-12 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
| DE602004016992D1 (de) | 2003-05-02 | 2008-11-20 | Elan Pharm Inc | 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazol-3-carbonsäureamid-derivate und verwandte verbindungen als bradykinin b1 rezeptor antagonisten zur behandlung von entzündlichen erkrankungen |
| ES2351393T3 (es) | 2003-05-26 | 2011-02-03 | Takeda Pharmaceutical Company Limited | Sulfopirroles. |
| US7872014B2 (en) | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
| US8048909B2 (en) | 2004-09-30 | 2011-11-01 | Takeda Pharmaceutical Company Limited | Proton pump inhibitors |
| US7977488B2 (en) | 2005-08-30 | 2011-07-12 | Takeda Pharmaceutical Company Limited | 1-heterocyclylsulfonyl, 2-aminomethyl, 5-(hetero-) aryl substituted 1-H-pyrrole derivatives as acid secretion inhibitors |
| US7994205B2 (en) | 2006-03-31 | 2011-08-09 | Takeda Pharmaceutical Company Limited | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors |
| US8933105B2 (en) | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| JP2009077078A (ja) | 2007-09-19 | 2009-04-09 | Brother Ind Ltd | 位置検出システム |
| US20090156642A1 (en) * | 2007-09-28 | 2009-06-18 | Takeda Pharmaceutical Company Limited | 5-Membered heterocyclic compound |
| WO2009041447A1 (ja) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | ５員複素環化合物 |
| PE20091846A1 (es) | 2008-05-19 | 2009-12-16 | Plexxikon Inc | DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS |
| KR20110036044A (ko) | 2008-07-18 | 2011-04-06 | 다케다 파머수티컬 컴패니 리미티드 | 벤즈아제핀 유도체들 및 히스타민 ｈ3 길항제로서 이들의 용도 |
-
2010
- 2010-03-25 EP EP10756174.8A patent/EP2412713B1/en active Active
- 2010-03-25 JP JP2011506117A patent/JP5552481B2/ja active Active
- 2010-03-25 KR KR1020117024240A patent/KR101656906B1/ko active Active
- 2010-03-25 GE GEAP201012426A patent/GEP20156222B/en unknown
- 2010-03-25 AU AU2010228220A patent/AU2010228220B2/en not_active Ceased
- 2010-03-25 CA CA2756086A patent/CA2756086A1/en not_active Abandoned
- 2010-03-25 MX MX2011009943A patent/MX2011009943A/es active IP Right Grant
- 2010-03-25 EA EA201171168A patent/EA019853B1/ru not_active IP Right Cessation
- 2010-03-25 UA UAA201112488A patent/UA107457C2/uk unknown
- 2010-03-25 MA MA34275A patent/MA33214B1/fr unknown
- 2010-03-25 CN CN201080023162.7A patent/CN102448953B/zh active Active
- 2010-03-25 SG SG2011067808A patent/SG174476A1/en unknown
- 2010-03-25 WO PCT/JP2010/055257 patent/WO2010110378A1/ja not_active Ceased
- 2010-03-25 US US13/260,507 patent/US8895588B2/en active Active
- 2010-03-25 BR BRPI1009090A patent/BRPI1009090A2/pt not_active IP Right Cessation
- 2010-03-25 NZ NZ595890A patent/NZ595890A/xx not_active IP Right Cessation
- 2010-03-25 PE PE2011001696A patent/PE20120618A1/es not_active Application Discontinuation
-
2011
- 2011-08-25 EC EC2011011419A patent/ECSP11011419A/es unknown
- 2011-09-19 IL IL215235A patent/IL215235A/en not_active IP Right Cessation
- 2011-09-21 TN TN2011000474A patent/TN2011000474A1/fr unknown
- 2011-09-23 DO DO2011000296A patent/DOP2011000296A/es unknown
- 2011-09-23 CL CL2011002351A patent/CL2011002351A1/es unknown
- 2011-10-11 ZA ZA2011/07435A patent/ZA201107435B/en unknown
- 2011-10-12 CR CR20110533A patent/CR20110533A/es unknown
- 2011-10-26 CO CO11144548A patent/CO6460700A2/es active IP Right Grant
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009004920A (es) | Nuevos derivados de aminopirimidina como inhibidores de plk1. | |
| MX2011008305A (es) | Compuestos de piridazinona. | |
| WO2009069736A1 (ja) | 含窒素化合物 | |
| WO2008108380A3 (en) | Pyrrole compounds | |
| WO2008108378A3 (en) | Bicyclic oxomorpholine derivative | |
| PH12013501873A1 (en) | Novel imidazo-oxazine compound or salt thereof | |
| UA105185C2 (uk) | Піроли | |
| MY148703A (en) | Polycyclic cinnamide derivatives | |
| MY160443A (en) | Nitrogen-containing heterocyclic compound and agricultural fungicide | |
| NZ592497A (en) | Derivatives of 1-amino-2-cyclobutylethylboronic acid | |
| WO2010014930A3 (en) | Piperidine derivatives as jak3 inhibitors | |
| UA99637C2 (uk) | Похідні піридину, заміщені гетероциклічним кільцем і фосфоноксиметильною групою, і протигрибковий засіб, що їх містить | |
| MX2011009146A (es) | Sales de adicion de aminas que contienen grupos hidroxilo y/o carboxilicos con derivados de acido aminonicotinico como inhibidores de dhodh. | |
| WO2008129951A1 (ja) | 新規なジベンジルアミン構造を有するピリミジン化合物及びこれを含有する医薬 | |
| WO2008140066A3 (en) | Pyridone derivatives as p38a mapk inhibitors | |
| WO2008126901A1 (ja) | 含窒素複素環化合物およびそれを含有する医薬組成物 | |
| MY159870A (en) | Piperazine compound capable of inhibiting prostaglandin d synthase | |
| WO2008136444A1 (ja) | 縮合複素環誘導体 | |
| WO2009118473A3 (fr) | Composés dérivés d'azétidines, leur préparation et leur application en thérapeutique | |
| AU2010332955A8 (en) | 3,4,4A,10B-tetrahydro-1H-thiopyrano-[4, 3-c] isoquinoline derivatives | |
| MX2014000937A (es) | Compuesto de amidina o sal del mismo. | |
| UA107457C2 (uk) | Похідні піразолу | |
| WO2008136378A1 (ja) | 新規なスルホンアミド誘導体またはその塩 | |
| MX2010010471A (es) | Derivado de tetrahidroisoquinolina novedoso. | |
| EA200700360A1 (ru) | Новые производные амида гетероциклической карбоновой кислоты |