M293434 八、新型說明： 【新型所屬之技術領域】 本創作相關於一種生物感測試紙，尤指一種可以保存 穩定、使用方便且低成本的生物感測試紙，其係在相應於 ，待測物進行特異性反應之反應區處上方設有一層^以 山封反區的始封片’藉此達到避免反應區受到外在環境 影響進而延緩生物感測試紙老化的目的。M293434 VIII. New description: [New technical field] This creation is related to a biological test paper, especially a bio-sensing test paper that can be stored stably, conveniently and at low cost, which corresponds to the object to be tested. At the top of the reaction zone where the specific reaction is carried out, a layer of the first sealing film of the mountain sealing zone is provided to prevent the reaction zone from being affected by the external environment and thereby delaying the aging of the biological test paper.
【先前技術】 a由於科技的進步，從前許多必須在醫院才能檢測的檢 ^現在大夕走向居豕測試的方向，目前市面上有許多用 =次後即可^且用於居家自行操作之生物感測試 箄置血糖、膽固醇、尿酸、pH值、農藥等 ί，適5非專業人1及居家護理方便使用，不但不會有污 :的情形發生’並且配合適當的生物感測器裝置，即可測 f出正讀的測量數值。 、 習用的生物感測試紙具有一基板、一導電膜 板及一反應區，在該基板上形成導電膜，該導電膜包含Γ :::ΐΓ:Γ的陽極部分和陰極部分，在該導電： 裸露出之部分-端形成工作= =參器裝置連接，並在該工作 不同以及不同原理而製作。當含有待測物流體=! 反應區後’流财之特纽彳—會歧賴物質= M293434 =並產生電化學變化，再由工作電極與參考電極傳導至 穴：二端之陰極接頭與陽極接頭，藉由與生物感測器 濃度^ 號’並經過計算而將訊號轉換成待測物 活性;==反應區中含有與待測物產生特異性反應的 響口 亥，性物質容易受到外在環境的影 為快、亲、“又的衫響，濕度愈高將導致試紙老化更 達到物感測試紙為了 ^保=的，於包裝時，係將複數片 ： 衣於一放有乾燥劑的乾燥罐中 = 罐子的乾燥，避免罐内的漫w軍，的使用而保持 數個試紙分裝於一個罐子中=法係將 Γ打開取出試紙，此時澄氣即會進二二需： 相收滢氣，但假若罐中保 有乾各 =:r"_罐已經打開 將複數試紙包裝於同— 響，故而此種 Γ縮短試紙的保存期限，並且需要增加‘造== 使用;為二2 紙:個乾燥罐中而導致 f’即將每一片試紙分_蜀一用；^1包裝㈣單片包 紙都分開包裝，因此不合麥變苴侦匕衣由於母一片試 不但會增加成本，並且：二=紙。然而單片包裝 撕開1呂泊取出試紙時，容易被！呂 M293434 箱所割傷。故而，如何克服生物感測試紙的保存問題以及 延緩老化’是為相關製造業者須改進之處。 【新型内容】 為了改善上述習 、 · 十另J 提供 ！於王初激列 試紙的最上層加設有-密封片用以保護反應區而避免受 到外在環境的影響，進而達到單片包裝而使用方便、攜帶 方便、延緩試紙老化及減低成本的目的。 為了達到上述目的，本創作之技術手段在於提供一種 ^物感測，試紙，其係包括一基板、一設於基板上之導電 膜、-覆蓋基板並裸露出部分導電臈之中隔板以及用以進 行反應並與裸露出之部分導電膜接觸的反應區，並在該中 隔板相應於反應區處上方設有—密封片，該密封片係黏貼 式地結合設於中隔板上並密封設置該反應區。 於本幻作之車乂佳貫施例中，該密封片可進一步包括 一撕開部且該㈣片呈—凸字型，較佳地，該撕開部係未 與該中隔板黏貼結合設置。另—方面，本創作所述之生物 感測試紙中，該中隔板相應於該反應區處設有一孔洞、凹 槽或'^開孔，較佳地，兮丨、、P1 & Λττ τγ/ 平乂 I土❿Θ孔洞為矩形且可設於近該中隔板 的一端且裸露出該導電膜之—端，而該凹槽可呈橫向且開 _中隔板之一側’或者，該凹槽可呈縱向且開口向中 板之ir而’另5玄開孔可為圓形或擴圓形穿設於該中隔板 中段處且裸露出導電膜之一端。 斤返之生物感測減紙中，較佳地，該導電膜至少包括 M293434 '工作電極及一參考電極，該導電膜可包括一導電銀膠層 設於該導電銀膠層上之導電碳粉層。所述之生物感^ 4紙中，較佳地，該基板為一矩形片體，並且該基板可 電絕緣基板。 ’ ^另一方面，於本創作之一較佳實施例的生物感測試 、、、氏，其係包括一基板、一設於基板上之導電膜、一覆蓋基 板及V私膜並裸露出部分導電膜之中隔板、用以進行反應 並與裸露出之部分導電膜接觸的反應區、一固定片及一密 f片’該固定片係設於該中隔板上且相應於該反應區之一 ^ &又有滴入口，藉此而與該中隔板在相應於反應區處 形成毛細現象空間’該密封片係黏貼式地設於該固定片上 ^目應於鼓應區處上方並⑽設㈣反應區。較佳地， 该密封片進一步可包括一撕開部且該密封片呈一凸字型。 本創作所述之生物感測試紙中，該固定片係進一步包 ^通虱孔’其係設在相應於該反應區設有滴入口之另 鈿。較佳地，該滴入口係設於 山 氣孔#y + 、 疋片之一鈿處，且該通 ::係7於近中段處而該反應區的長度係介於該滴入口 及通氣孔間的距離長度。另外， ^ ^ ^ . 该中隔板在相應於該反應 槽中。 亥反應區係設於該開孔或凹 用時：ΐ將作之生物感蜊試紙可以單片包裝，並於使 用日才僅需將密封片撕去即可 反應區受到外在環境的影響不但可以達到避免 、尤其疋濕度的影響），並且 M293434 也可延緩試紙老彳卜， 質，另可達到方便样册你可田增加檢測的準確性，提高品 而加設的固定片二用方便以及節省成本的目的。 而穩定與反應區吸人反應區的流體體積，進 準確度。 仃…的流體量，達到檢測穩定且提高 【實施方式】 〇）、一導電膜（2 〇 ) 體示=1:及圖=其係本創作較佳實施例之立 M n、、一纟創作之生物感測試紙包括-基板 中隔板 0 )、至少 個反應區^ 4 〇 )及一密封片（5 0 )，該基板（丄〇 ) 可為-矩形片體’較佳地為具有電絕緣特性。 該導電膜（2 0)塗佈於基板（1〇)上，且較佳地 包括-導電銀膠層（22) 導電碳粉層（24)，該 導電碳粉層（2 4)覆蓋於導電銀膠層（2 導電銀膠層（22)及導電碳粉層（24=少= -條電極’較佳地’該導電膜（2 〇 )之—端與基板（工 0 )之長邊呈縱向且彼此呈平行，其係心與生物感測器 裝置相接觸而偵測電化學的改變。較佳地，該導電膜（2 〇)至少包括一工作電極及一參考電極。 、 該中隔板（3 0 )覆蓋於部分基板（丄〇 )及導電膜 (2 0 )上，且裸露出導電臈（2 〇 )之—端，裸露出之 導電膜（2 0 )的一端分別用以與生物感測哭導 通偵測電化學的改變，另該中隔板（3〇)二^ 一孔洞（3 1 )而稞露出該導電膜（2 〇 )之另一端，較 M293434 佳地’該孔洞（3 1 )係為矩形。另外，該中隔板（3 〇) 具有電絕緣特性，而該導電銀膠層（22)並未設於相應 於該孔洞（3 1 )處。 —該反應區（4 0 )係覆蓋於基板（1 〇 )及部分導電 膜（2 0 )上且相應於該中隔板（3 〇 )之孔洞（3丄） 處，其係含有生物活性物質（例如酵素）、酵素輔助因子、 安定劑（如高分子聚合物）及緩衝溶液等。該生物活性物 質需適當保存’否則容易受到環境（尤其是濕度）的影響 而減U丨生&加其老化逮度，縮短保存期限並導致檢 本創作於該反應區（4 〇 0)。較佳地’㈣封片（5〇)設有— f撕開部（52)係凸設於該密封片（5〇)之一端Λ 未與該中隔板（3〇)相黏貼結合，且 凸字型。該密封片（50)係覆蓋 :)中：板丄=孔洞（31)上方相應於反應區" 0 )上且σ亥饴封片（5 〇 )係與中隔柘Γ 結合，並與該中隔板（3 ^ ）相黏貼 〇)，該密封片（5=)用狀態遮蓋該反應區(4 受到環境的影響，方便使用護反應1 (4〇)避免 撕開，避免過早暴露於空氣中、，❹時再將密封片（5 0 ) 計可幫助使用者將密封片（^而4撕開部（5 2)的設 山去了月（5 〇 )撕去。 本創作之生物感測試紙使 (5 2 )將該密封片（5 〇 、百先利用該撕開部 50)撕開，即可裸露出反應區（4 M293434 0 ) ’將含有待測物流體經由毛細現象吸入或者直接滴入 反應區（4〇)中與反應區（40)進行反應。當含有待 測物流體接觸反應區（4 0 )後而使得乾燥試劑溶解並進 行反應’進而產生電化學的改變，經由與反應區（4 0 ) 接觸之導電臈（2 0 )電極傳導，而與生物感測器裝置接 觸並由生物感測器裝置接收訊號，再將訊號計算轉換成待 測物7辰度顯示。 配合第三圖觀之，其係本創作第二種較佳實施例之生 .物感測試紙，其係與第一種較佳實施例之差別係在該密封 片（5 0 )與中隔板（3 〇 )間加設有一固定片（4 2 )， 該固定片（4 2 )係設於該中隔板（3 0 )上且包括有一 通氣孔（4 4 )及一滴入口（ 4 6 )，該通氣孔（4 4 ) 係位在相應於該中隔板（3 〇 )孔洞（3 1 )之一端上方， 較佳地’該通氣孔（4 4 )係位於近中段處，而該滴入口 (4 6 )係設於相應於該中隔板（3 〇 )孔洞（3 1 )之 ，另一鈿上方，較佳地，該滴入口（ 4 6 )係設於近邊緣處， 而該反應區（4 1 )係設於該中隔板（3 〇 )之孔洞（3 1 )内且大小約相應於該固定片（4 2 )之通氣孔（4 4) 與滴入口（ 4 6 )間的距離長度。使用時，係先將密封片 (5 0 )撕去，此時將含有待測物的流體滴入該滴入口（ 4 6 )中，經由固定片（4 2 )與中隔板（3 〇 )間的毛細 現象而進入反應區（4 1 )中，再加上通氣孔（44)的 設計，可以加速流體進入反應區（4丄）中而與活性物質 進行反應。另外，經由加設固定片（4 2 )的設計，可以 M293434 固疋進入反應區（4 1 )内的流體體積，達到檢測更為準 確的目的。 再配δ苐四及五圖觀之，其係本創作第三種較佳實施 例之生物感測試紙，其係包括一基板（1 〇 a )、一導電 膜（2〇a)〜、~中隔板（30a)、至少一個反應區（4 0 a)及一役封片（5 〇 a)，於中隔 凹設有至少-凹槽（32)而裸露出導電w(2):at 一端二該導電膜（2 0a)包括-導電銀膠層（2 2a)及 一覆蓋於導電銀膠層（2 2a)上之導電碳粉層（2 4小 °亥凹抬（3 2 )可以呈橫向且開口向該中隔板（3 〇 a) 之一側’或者該凹槽（3 2 )可以呈縱向且開口向該中隔 板（3 〇〇之一端’該密封片（5 0a)包括一撕開部（5 2 a ) D亥撕開邛（5 2 a )係連接設於該密封片（5 〇 & ) 之-側。藉此’使用前，由該撕開部（5 2 =片（5〇a)撕去，而使用時，含有待測物流體:: 可經由毛細現象吸入反應區（4〇a)中而進行反 ㈣第三種較佳實施例之其他結構與本創作第一種較 貫施例的結構相似。 配合第六圖觀之’其係本創作第四種較佳實施例之生 =測试紙，其係包括一基板（1〇b)、一導 〇b)、-中隔板（3〇b)、至少—個反應 及-密封片（5〇b)，該導電膜（2〇b)包 膠層Q2b)及-覆蓋於導電銀膠層（22b)上之^ 碳粉層（2 4b)。該中隔板（3 〇b)具有一開孔（電 M293434 »亥開孔（3 4 )穿設於該中隔板（3 〇b)中段處且裸露 =導電膜（2 Ob)之一端，較佳地，該開孔（3 4)係 呈圓形或橢圓形，而該密封片（5 〇b)包括一用以方便 使用者撕去密封片（5 〇b)的撕開部（5 2b)。藉此， 含有待測物流體即可經由直接滴入的方式與反應區〇 H觸而進行反應，其他結構與本㈣第三種較佳實施 例、、Ό構相似。 士該生物感測試紙可以用以測量農藥、血糖、尿酸、膽 ^等等’若為測量農藥量，則將可能含有農藥的液體^ 含有農藥濃度的液體滴人反應區中，待測的農藥即 =應：中所含有的特異性活性物質反應，經由導電膜 傳‘電化學的改變而檢測出農藥的濃度。 、 猎此，在中隔板上相應於反應區處加設密封片即可 到保護反應區内活性物質的目的，可以避 =響反應區物質’也不會因為複數片試紙保存於= 2子中而導致開瓶時影響其他的試紙，並可達到延緩試紙 老化:增加試紙穩定性進而增加試紙檢測準確性之 綜上所述，本創作具有以下優點·· 一、^生物感測試紙最上層設有-密封片，因此可以 將反應區完全密封住而避免外| 到延緩試紙老化的目的。在^兄影響反應區，即可達 以^密封片撕去即可裸露出反應區用 以進仃反應，故而方便使用者使用。 三、於每-片生物感測試紙最上層加設密封片不若單 12 M293434 片用鋁箔包裝所需耗費更多成本，但 益，故而可以降低成本。 1=1違到相同的效 四、 將每一片試紙經由加設密封片封 乾燥罐包裝的費用，因此可以節省成本。、去使用 五、 將生物感測試紙藉由單片包裝 使用者攜帶外出，且容易攜帶。 式，可以方便[Previous technology] a Due to the advancement of science and technology, many of the previous inspections that must be detected in the hospital are now in the direction of the test of the residence. Currently, there are many organisms on the market that can be used at home and used for home operation. Sense test set blood sugar, cholesterol, uric acid, pH, pesticides, etc., suitable for non-professionals 1 and home care convenient use, not only will not be contaminated: the situation occurs 'and with appropriate biosensor device, ie It can measure the measured value of f reading. The conventional biosensor test paper has a substrate, a conductive film plate and a reaction zone on which a conductive film is formed, the conductive film comprising an anode portion and a cathode portion of Γ :::ΐΓ:Γ, in the conductive: The exposed part - the end forms the work = = the device is connected, and is made in different work and different principles. When it contains the fluid to be tested =! After the reaction zone, 'the flow of the special 彳 彳 会 会 = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = The connector converts the signal into the activity of the analyte by calculation with the biosensor concentration ^; and the reaction zone contains a specific reaction with the analyte, and the substance is easily exposed. In the environment, the shadow is fast, pro, "the shirt is ringing, the higher the humidity will lead to the aging of the test paper and the physical test paper for the guarantee. In the packaging, the film will be a plurality of tablets: In the dry tank = dry the jar, avoid the use of the tank, and keep several test strips in one jar. The collection of suffocating gas, but if the cans are kept dry =: r " _ cans have been opened to pack the multiple test strips in the same -, so this Γ shortens the shelf life of the test strips, and needs to increase 'made == use; 2 paper: a dry can and cause f' to be each piece The test paper is divided into _ 蜀 one; ^1 packaging (four) single-piece wrapping paper is packaged separately, so the maiden 苴 苴 匕 由于 由于 由于 由于 由于 由于 由于 由于 由于 由于 由于 由于 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母 母When the test paper is taken out, it is easy to be cut by the Lu M293434 box. Therefore, how to overcome the preservation problem of the biological test paper and delay the aging is a improvement for the relevant manufacturers. [New content] In order to improve the above, Ten other J offers! On the top layer of the initial test paper of Wang Chu, the sealing sheet is used to protect the reaction zone from external environment, which is convenient to use, easy to carry, and delays the aging of the test paper. The purpose of reducing the cost is to provide the object sensing method, which comprises a substrate, a conductive film disposed on the substrate, covering the substrate and exposing a portion of the conductive conductive layer. a middle partition plate and a reaction zone for reacting and contacting a portion of the exposed conductive film, and wherein the middle partition is provided with a sealing sheet corresponding to the reaction zone, The sealing sheet is adhesively combined on the middle partition plate and sealingly sets the reaction zone. In the embodiment of the illusion, the sealing sheet may further comprise a tearing portion and the (four) sheet is convex. Preferably, the tearing portion is not adhesively bonded to the middle partition. In another aspect, in the biosensor test paper of the present invention, the middle partition has a hole corresponding to the reaction zone. , groove or '^ opening, preferably, 兮丨,, P1 & Λττ τγ / 乂 乂 I soil hole is rectangular and can be located near one end of the partition and expose the conductive film - End, and the groove may be lateral and open one side of the partition plate 'or, the groove may be longitudinal and open to the middle plate ir and the other 5 open holes may be round or rounded It is disposed at the middle of the middle partition and exposes one end of the conductive film. Preferably, the conductive film comprises at least a M293434 'working electrode and a reference electrode, and the conductive film may comprise a conductive silver powder layer on the conductive silver adhesive layer. Floor. In the biosensor 4, preferably, the substrate is a rectangular sheet, and the substrate can electrically insulate the substrate. On the other hand, the biosensor test of a preferred embodiment of the present invention includes a substrate, a conductive film disposed on the substrate, a cover substrate, and a V private film and exposed portions. a separator in the conductive film, a reaction zone for reacting and contacting a portion of the exposed conductive film, a fixing piece and a dense piece of the fixing piece are disposed on the intermediate plate and corresponding to the reaction zone One of the ^ & has a drop inlet, thereby forming a capillary phenomenon space corresponding to the middle partition at the reaction zone. The sealing sheet is adhesively disposed on the fixing sheet and should be above the drum area. And (10) set (4) reaction zone. Preferably, the sealing sheet further comprises a tearing portion and the sealing sheet has a convex shape. In the biosensor test paper of the present invention, the fixing sheet is further provided with a through-hole which is provided in the other side corresponding to the reaction zone. Preferably, the drop inlet is disposed at one of the stomata #y + and the sputum, and the passage: the system 7 is at the near middle section and the length of the reaction zone is between the drop inlet and the vent hole The length of the distance. In addition, ^ ^ ^ . The middle partition is in the reaction tank. The reaction zone of the hai is set in the opening or recess: the bio-sensing test paper to be smashed can be packaged in a single piece, and only the sealing piece is torn off on the use day, the reaction zone is affected by the external environment. Can avoid the impact of avoiding, especially the humidity, and M293434 can also delay the test strip, the quality, and the convenient sample book, you can increase the accuracy of the test, improve the product and add the fixed piece and easy to use The purpose of cost saving. The stability and the reaction zone absorb the fluid volume of the reaction zone, and the accuracy is improved. The amount of fluid in the ,... is stable and improved. [Embodiment] 一), a conductive film (2 〇) body =1: and Fig. = the MN, the creation of the preferred embodiment of the present invention The biosensor test paper comprises - a spacer 0 in the substrate, at least one reaction zone ^ 4 〇) and a sealing sheet (50), and the substrate (丄〇) can be a - rectangular sheet ' preferably having electricity Insulation properties. The conductive film (20) is coated on the substrate (1), and preferably comprises a conductive silver paste layer (22) conductive carbon powder layer (24), the conductive carbon powder layer (24) covering the conductive Silver glue layer (2 conductive silver glue layer (22) and conductive carbon powder layer (24 = less = - strip electrode 'better' the end of the conductive film (2 〇) and the substrate (work 0) Longitudinally and in parallel with each other, the core is in contact with the biosensor device to detect an electrochemical change. Preferably, the conductive film (2 〇) includes at least a working electrode and a reference electrode. The plate (30) covers a portion of the substrate (丄〇) and the conductive film (20), and the end of the conductive 臈 (2 〇) is exposed, and one end of the exposed conductive film (20) is used for The biological sensing crying conduction detects the change of the electrochemical, and the middle partition (3 〇) two holes (3 1 ) exposes the other end of the conductive film (2 〇), which is better than the M293434 (3 1 ) is rectangular. In addition, the middle partition (3 〇) has electrical insulating properties, and the conductive silver adhesive layer (22) is not disposed at the corresponding hole (3 1 ). The region (40) covers the substrate (1 〇) and a portion of the conductive film (20) and corresponds to the hole (3丄) of the middle separator (3 ,), which contains a biologically active substance (such as an enzyme) ), enzyme cofactors, stabilizers (such as high molecular weight polymers), buffer solutions, etc. The bioactive substances need to be properly preserved 'otherwise susceptible to the environment (especially humidity) minus U Shengsheng & plus its aging arrest Degree, shortening the shelf life and causing the specimen to be created in the reaction zone (4 〇 0). Preferably, the (4) cover (5 〇) is provided with a - f tearing portion (52) protruding from the sealing sheet (5) 〇) One end Λ is not bonded to the middle partition (3〇), and is convex type. The sealing sheet (50) is covered:) Medium: 丄 = hole above the hole (31) corresponding to the reaction zone " 0) The upper σ 饴 饴 ( 5 5 5 5 5 5 柘Γ 柘Γ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ σ 4 Under the influence of the environment, it is convenient to use the protective reaction 1 (4〇) to avoid tearing, avoid premature exposure to the air, and then seal the sealing piece (50) It can help the user to tear off the sealing piece (^4 and the tearing part (5 2) of the mountain (5 〇). The biosensor test paper of this creation makes (5 2 ) the sealing piece (5 〇 , the first use of the tearing portion 50) to tear open, the bare reaction zone (4 M293434 0 ) 'to contain the fluid to be tested through the capillary phenomenon or directly into the reaction zone (4 〇) and the reaction zone ( 40) carrying out the reaction. When the fluid containing the analyte is contacted with the reaction zone (40), the dry reagent is dissolved and reacted', thereby generating an electrochemical change, via the conductive enthalpy (2 0) in contact with the reaction zone (40). The electrode is conductive, and is in contact with the biosensor device and receives the signal by the biosensor device, and then converts the signal calculation into a display of the object to be tested. In conjunction with the third figure, it is the second preferred embodiment of the present invention. The texture test paper is different from the first preferred embodiment in the sealing sheet (50) and the septum. A fixing piece (4 2 ) is disposed between the plate (3 〇), and the fixing piece (4 2 ) is disposed on the middle partition plate (30) and includes a vent hole (4 4 ) and a drop inlet (4 6 ) The vent hole (4 4 ) is located above one end corresponding to the middle partition (3 〇) hole (3 1 ), preferably the vent hole (4 4 ) is located at a near middle portion, and The drop inlet (4 6 ) is disposed above the other partition corresponding to the middle partition (3 )), preferably, the drop inlet (46) is disposed at the near edge, and The reaction zone (4 1 ) is disposed in the hole ( 3 1 ) of the middle partition (3 ) ) and has a size corresponding to the vent hole ( 4 4 ) of the fixing piece ( 4 2 ) and the drip inlet ( 4 6 ) The length of the distance between). In use, the sealing sheet (50) is first peeled off, at which time the fluid containing the analyte is dropped into the drop inlet (46), via the fixing piece (4 2 ) and the middle partition (3 〇). The capillary phenomenon enters the reaction zone (41), and the design of the vent (44) accelerates the entry of the fluid into the reaction zone (4丄) to react with the active material. In addition, through the design of the fixed piece (4 2 ), the volume of fluid entering the reaction zone (4 1 ) can be fixed by M293434 for more accurate detection. Further, with δ苐4 and 5, it is a biosensor test paper of a third preferred embodiment of the present invention, which comprises a substrate (1 〇a) and a conductive film (2〇a)~,~ The intermediate partition (30a), the at least one reaction zone (40 a), and the one seal (5 〇a) are provided with at least a groove (32) in the septum recess to expose the conductive w(2): at one end The conductive film (20a) comprises a conductive silver paste layer (2 2a) and a conductive carbon powder layer covering the conductive silver paste layer (2 2a) (2 4 small ° 凹 concave lift (3 2 ) can be Transversely and open to one side of the middle partition (3 〇a) or the groove (32) may be longitudinal and open to the middle partition (one end of the 3'' the sealing sheet (50a) A tearing portion (5 2 a ) is provided on the side of the sealing sheet (5 〇 & ). By this, the tearing portion (5 2 is used before use) = sheet (5〇a) is torn off, and when used, contains the fluid to be tested:: can be inhaled into the reaction zone (4〇a) via capillary phenomenon and reversed. (IV) Other structures and the third preferred embodiment The structure of the first comparative example is similar. The present invention is the fourth preferred embodiment of the present invention. The test paper comprises a substrate (1〇b), a guide b), a middle partition (3〇b), at least— a reaction and sealing sheet (5〇b), the conductive film (2〇b) cladding layer Q2b) and a carbon powder layer (24b) covering the conductive silver paste layer (22b). The plate (3 〇b) has an opening (electric M293434 » hai hole (3 4 ) is disposed at a middle portion of the middle partition (3 〇b) and exposed = one end of the conductive film (2 Ob), preferably The opening (34) is circular or elliptical, and the sealing piece (5 〇b) includes a tearing portion (52b) for facilitating the user to tear off the sealing piece (5 〇b). Thereby, the fluid containing the analyte can be reacted with the reaction zone by direct instillation, and the other structures are similar to the third preferred embodiment and the structure of the fourth embodiment. Can be used to measure pesticides, blood sugar, uric acid, gallbladder, etc. 'If it is to measure the amount of pesticides, it will contain liquids containing pesticides ^ Liquid containing pesticide concentration in the human reaction zone, the pesticide to be tested = should be: Specific The active material reacts, and the concentration of the pesticide is detected by the electrochemical change of the conductive film. In this case, the sealing sheet is added to the reaction plate at the intermediate partition to protect the active material in the reaction zone. Can avoid the sound of the reaction zone material 'will not affect the other test papers when the bottle is stored in the = 2, which can affect the aging of the test paper: increase the stability of the test paper and increase the accuracy of the test paper. As described above, the present invention has the following advantages: 1. The uppermost layer of the biosensor test paper is provided with a sealing sheet, so that the reaction zone can be completely sealed to avoid the purpose of delaying the aging of the test paper. In the influence of the reaction zone of the brother, the sealing sheet can be peeled off to expose the reaction zone for the reaction, so it is convenient for the user to use. 3. Adding a sealing sheet to the top layer of each bio-sensing test paper. 12 M293434 The sheet is wrapped in aluminum foil, which requires more cost, but benefits, so it can reduce costs. 1=1 violates the same effect. 4. Each piece of test paper is sealed with a sealing sheet to seal the dry can, so it can save costs. 5, the bio-sensing test paper is carried out by a single piece of the user, and is easy to carry. Style, can be convenient
六、精由在生物感測試紙最上層設宓 應區密封，可以達到枝抽取的目的，式將反 將單片包裝需要費時胸撕開，才能將試：出= 驗的不方便性。 ^取出進订檢 极上興岔封片間加設有 :定吸入反應區之流體體積的目的，進而增二=準達: 八、於回疋月中設有一通氣孔 流體進入反應區’進而達到縮短檢測時；二：待測物之Sixth, the essence is set on the top layer of the biological test paper. The area should be sealed, which can achieve the purpose of branch extraction. The formula will reverse the time-consuming chest tearing of the single piece of packaging, in order to test: the inconvenience of the test. ^ Take out the check-in detector and install the seal between the sheets. The purpose of setting the volume of the fluid in the reaction zone is to increase the second = quasi-reach: 8. Set a vent hole into the reaction zone during the return month. When the detection is shortened; two: the object to be tested
雖'然前述實例說日林㈣之具體事實 可能的修正及改變均不㈣以下主張之瞭解任何 精神及範疇。 申明專利範圍的 【圖式簡單說明】 第-圖係本創作第—種實施例之立體示意圖 第二圖係本創作第1實_之立體分解圖。 第三圖係本創作第二種實施例之立體分解圖。 第四圖係本創作第三種實施例之立體示意圖。 第五圖係本創作第四圖實施例之立體分解圖。 M293434 .第六圖係本創作第四種實施例之立體分解圖。 【主要元件符號說明】 (1 ◦ ) ( 1 0 a) ( 1 ◦ b)基板 (2 〇）（2 〇a) ( 2 Ob)導電膜 (2 2 ) ( 2 2a) ( 2 2b)導電銀膠層 (2 4 ) ( 2 4 a) ( 2 4b)導電碳粉層 (3 0 ) ( 3 0 a) ( 3 Ob)中隔板 (3 1 )孔洞 > (3 2 )凹槽 (3 4 )開孔 (4 0 ) ( 4 〇a) ( 4 Ob) ( 4 1 )反應區 (4 2 )固定片 (4 4 )通氣孔 (4 6 )滴入口 (5 0 ) ( 5 0 a) ( 5 0 b)密封片 > (5 2 )撕開部 14Although the foregoing examples say that the specific facts of Rilin (4) are likely to be amended and changed, (4) the following claims are understood for any spirit and scope. [Simplified description of the scope of the patent] The first diagram is a three-dimensional schematic diagram of the first embodiment of the present invention. The third figure is an exploded perspective view of the second embodiment of the present creation. The fourth figure is a perspective view of a third embodiment of the present creation. The fifth figure is an exploded perspective view of the fourth embodiment of the present creation. M293434. The sixth figure is a perspective exploded view of the fourth embodiment of the present creation. [Explanation of main component symbols] (1 ◦ ) ( 1 0 a) ( 1 ◦ b) Substrate (2 〇) (2 〇a) ( 2 Ob) Conductive film (2 2 ) ( 2 2a) ( 2 2b) Conductive silver Adhesive layer (2 4 ) ( 2 4 a) ( 2 4b) Conductive carbon powder layer (3 0 ) ( 3 0 a) ( 3 Ob) partition (3 1 ) hole > (3 2 ) groove (3 4) Opening (4 0 ) ( 4 〇 a) ( 4 Ob) ( 4 1 ) Reaction zone (4 2 ) Fixing plate (4 4 ) Venting hole (4 6 ) Drip inlet (5 0 ) ( 5 0 a) ( 5 0 b) sealing sheet > (5 2 ) tearing portion 14