TW201129359A - Pharmaceutical composition for the treatment of COPD - Google Patents
Pharmaceutical composition for the treatment of COPDInfo
- Publication number
- TW201129359A TW201129359A TW099145166A TW99145166A TW201129359A TW 201129359 A TW201129359 A TW 201129359A TW 099145166 A TW099145166 A TW 099145166A TW 99145166 A TW99145166 A TW 99145166A TW 201129359 A TW201129359 A TW 201129359A
- Authority
- TW
- Taiwan
- Prior art keywords
- copd
- treatment
- pharmaceutical composition
- formoterol
- glycopyrronium bromide
- Prior art date
Links
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- VPNYRYCIDCJBOM-UHFFFAOYSA-M Glycopyrronium bromide Chemical compound [Br-].C1[N+](C)(C)CCC1OC(=O)C(O)(C=1C=CC=CC=1)C1CCCC1 VPNYRYCIDCJBOM-UHFFFAOYSA-M 0.000 abstract 2
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 abstract 2
- 229960002848 formoterol Drugs 0.000 abstract 2
- 229960002462 glycopyrronium bromide Drugs 0.000 abstract 2
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 229950000210 beclometasone dipropionate Drugs 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 229940071648 metered dose inhaler Drugs 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
- B65B31/003—Adding propellants in fluid form to aerosol containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B7/00—Closing containers or receptacles after filling
- B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
- B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
- B65B7/2842—Securing closures on containers
- B65B7/285—Securing closures on containers by deformation of the closure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Mechanical Engineering (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09180671 | 2009-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201129359A true TW201129359A (en) | 2011-09-01 |
| TWI495468B TWI495468B (zh) | 2015-08-11 |
Family
ID=42107420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW099145166A TWI495468B (zh) | 2009-12-23 | 2010-12-22 | 治療慢性阻塞性肺病(copd)之醫藥組成物 |
Country Status (40)
| Country | Link |
|---|---|
| US (3) | US20110150782A1 (zh) |
| EP (1) | EP2515855B3 (zh) |
| JP (2) | JP5914354B2 (zh) |
| KR (2) | KR101757951B1 (zh) |
| CN (2) | CN104055765B (zh) |
| AR (2) | AR079726A1 (zh) |
| AU (3) | AU2010334859A1 (zh) |
| BR (1) | BR112012015337B8 (zh) |
| CA (1) | CA2785321C (zh) |
| CL (1) | CL2012001705A1 (zh) |
| CO (1) | CO6541628A2 (zh) |
| CY (2) | CY1115116T1 (zh) |
| DK (1) | DK2515855T6 (zh) |
| EA (2) | EA027778B1 (zh) |
| ES (1) | ES2468840T7 (zh) |
| FI (2) | FI2515855T6 (zh) |
| GE (1) | GEP20156311B (zh) |
| HR (1) | HRP20140582T4 (zh) |
| HU (1) | HUS1800001I1 (zh) |
| IL (1) | IL260932B (zh) |
| LT (1) | LTC2515855I2 (zh) |
| LU (1) | LUC00060I2 (zh) |
| MA (1) | MA33823B1 (zh) |
| MX (1) | MX2012006878A (zh) |
| MY (1) | MY156949A (zh) |
| NL (1) | NL300923I2 (zh) |
| NO (1) | NO2018001I2 (zh) |
| NZ (1) | NZ600790A (zh) |
| PE (2) | PE20121396A1 (zh) |
| PH (1) | PH12012501066A1 (zh) |
| PL (1) | PL2515855T6 (zh) |
| PT (1) | PT2515855E (zh) |
| RS (1) | RS53391B2 (zh) |
| SG (1) | SG181868A1 (zh) |
| SI (1) | SI2515855T1 (zh) |
| TN (1) | TN2012000269A1 (zh) |
| TW (1) | TWI495468B (zh) |
| UA (1) | UA113832C2 (zh) |
| WO (1) | WO2011076843A2 (zh) |
| ZA (1) | ZA201204615B (zh) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2785321C (en) * | 2009-12-23 | 2018-08-21 | Chiesi Farmaceutici S.P.A. | Combination therapy for copd |
| MX340264B (es) * | 2009-12-23 | 2016-07-04 | Chiesi Farm Spa | Formulacion de aerosol para la enfermedad pulmonar obstructiva cronica. |
| ES2468835T3 (es) * | 2009-12-23 | 2014-06-17 | Chiesi Farmaceutici S.P.A. | Terapia combinada para EPOC |
| RU2013142268A (ru) * | 2011-02-17 | 2015-03-27 | Сипла Лимитед | Фармацевтическая композиция |
| CN103874483B (zh) | 2011-10-11 | 2017-09-12 | 奇斯药制品公司 | 包衣了脂肪酸的β‑激动剂的晶体微粒 |
| JP2016503390A (ja) * | 2012-10-23 | 2016-02-04 | シプラ・リミテッド | 医薬組成物 |
| PT3019153T (pt) * | 2013-07-11 | 2018-12-04 | Chiesi Farm Spa | Formulação de pó seco que compreende um anticolinérgico, um corticosteroide e um beta-adrenérgico para administração por inalação |
| ES2666905T4 (es) * | 2013-12-30 | 2018-06-07 | Chiesi Farmaceutici S.P.A. | Composición en solución para aerosol estable presurizada de una combinación de bromuro de glicopirronio y formoterol |
| SI3089735T1 (sl) | 2013-12-30 | 2018-10-30 | Chiesi Farmaceutici S.P.A. | Sestavek stabilne aerosolne raztopine pod tlakom, ki vsebuje glikopironijev bromid in formoterol |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039620B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US9554992B2 (en) * | 2014-06-09 | 2017-01-31 | Chiesi Farmaceutici S.P.A. | Inhalation particles comprising a combination of an anticholinergic, a corticosteroid and a beta-adrenergic |
| GB201416909D0 (en) * | 2014-09-25 | 2014-11-12 | Prosonix Ltd | Method of forming concentrated solution |
| WO2016170518A1 (en) | 2015-04-24 | 2016-10-27 | Glenmark Specialty S.A. | Pharmaceutical compositions comprising arformoterol and glycopyrronium |
| TWI731891B (zh) | 2015-11-16 | 2021-07-01 | 義大利商吉斯藥品公司 | 含有抗膽鹼劑、皮質類固醇及β-腎上腺素之乾粉配方之製備方法 |
| GB2545025A (en) * | 2015-12-04 | 2017-06-07 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
| EP3436115B1 (en) | 2016-03-31 | 2021-07-28 | Chiesi Farmaceutici S.p.A. | Aerosol inhalation device |
| US10098837B2 (en) * | 2016-07-28 | 2018-10-16 | Chiesi Farmaceutici S.P.A. | Combination therapy for COPD |
| PE20191043A1 (es) * | 2016-09-19 | 2019-08-06 | Mexichem Fluor Sa De Cv | Composicion farmaceutica |
| ES2877575T3 (es) | 2016-09-19 | 2021-11-17 | Mexichem Fluor Sa De Cv | Composición farmacéutica que comprende salmeterol |
| ES2956521T3 (es) * | 2016-09-19 | 2023-12-22 | Mexichem Fluor Sa De Cv | Composición farmacéutica que comprende bromuro de tiotropio |
| CN110582269B (zh) | 2017-05-11 | 2023-02-28 | 奇斯药制品公司 | 制备包含抗胆碱能药、皮质类固醇和β-肾上腺素能药的干粉制剂的方法 |
| KR20220155609A (ko) | 2017-05-11 | 2022-11-23 | 키에시 파르마슈티시 엣스. 피. 에이. | 항콜린제, 코르티코스테로이드 및 베타-아드레날린성 약물을 포함하는 건조 분말 제제의 제조 방법 |
| MA52756A (fr) * | 2018-06-04 | 2021-04-14 | Lupin Inc | Compositions pharmaceutiques stables pour inhalateurs doseurs sous pression |
| CN114502146A (zh) * | 2019-12-02 | 2022-05-13 | 奇斯药制品公司 | 用于加压定量吸入器的不锈钢罐 |
| US20230270754A1 (en) | 2020-07-31 | 2023-08-31 | Chemo Research, S.L. | Combination therapy for inhalation administration |
| CA3193038A1 (en) | 2020-10-09 | 2022-04-14 | Enrico Zambelli | A pharmaceutical formulation for pressurised metered dose inhaler |
| WO2023227782A1 (en) | 2022-05-27 | 2023-11-30 | Chiesi Farmaceutici S.P.A. | A pharmaceutical formulation for pressurised metered dose inhaler |
| CN119255820A (zh) | 2022-05-27 | 2025-01-03 | 奇斯药制品公司 | 用于加压定量吸入器的药物制剂 |
| WO2023227781A1 (en) | 2022-05-27 | 2023-11-30 | Chiesi Farmaceutici S.P.A. | A pharmaceutical formulation for pressurised metered dose inhaler |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2956062A (en) | 1959-02-26 | 1960-10-11 | Robins Co Inc A H | Esters of amino alcohols |
| WO1994013263A1 (en) | 1992-12-09 | 1994-06-23 | Jager Paul D | Stabilized medicinal aerosol solution formulations |
| ATE283033T1 (de) | 1998-07-24 | 2004-12-15 | Jago Res Ag | Medizinische aerosolformulierungen |
| EP1102579B1 (de) * | 1998-08-04 | 2003-03-19 | Jago Research Ag | Medizinische aerosolformulierungen |
| US20060171899A1 (en) * | 1998-12-10 | 2006-08-03 | Akwete Adjei | Water-stabilized aerosol formulation system and method of making |
| IT1317720B1 (it) | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
| GB0008660D0 (en) | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
| BR0015884A (pt) * | 2000-05-22 | 2003-07-08 | Chiesi Farma Spa | Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados |
| US20060257324A1 (en) * | 2000-05-22 | 2006-11-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical solution formulations for pressurised metered dose inhalers |
| DE50211045D1 (de) | 2001-03-30 | 2007-11-22 | Jagotec Ag | Medizinische aerosolformulierungen |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| EP1321159A1 (en) | 2001-12-21 | 2003-06-25 | CHIESI FARMACEUTICI S.p.A. | Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices |
| KR100947409B1 (ko) | 2002-03-01 | 2010-03-12 | 키에시 파르마슈티시 엣스. 피. 에이. | 포모테롤 초미세 조성물 |
| EP1575588A1 (en) | 2002-12-16 | 2005-09-21 | Boehringer Ingelheim Pharma GmbH & Co.KG | Tiotropium containing hfc solution formulations |
| AR041873A1 (es) * | 2003-10-30 | 2005-06-01 | Pablo Cassara Srl Lab | Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante |
| PT1713473E (pt) | 2004-02-06 | 2013-05-13 | Meda Pharma Gmbh & Co Kg | Combinação de anticolinérgicos e glucocorticóides para o tratamento a longo prazo de asma e copd |
| DE602005007708D1 (de) * | 2004-02-06 | 2008-08-07 | Meda Pharma Gmbh & Co Kg | Neue kombination von anticholinergen und beta mimetika zur behanldung von atemwegserkrankungen |
| GB0410399D0 (en) | 2004-05-10 | 2004-06-16 | Arakis Ltd | The treatment of respiratory disease |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| EP1616567A1 (en) | 2004-07-16 | 2006-01-18 | Boehringer Ingelheim Pharma GmbH & Co.KG | Medicaments for inhalation comprising PDE IV inhibitors and glycopyrrolate salts |
| GB0505545D0 (en) | 2005-03-17 | 2005-04-27 | Glaxo Group Ltd | Inhalation devices |
| EP2484382A1 (en) | 2005-03-30 | 2012-08-08 | Schering Corporation | Medicament comprising a phosphodiesterase IV inhibitor in an inhalable form |
| GB0523653D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| KR20080032136A (ko) | 2005-08-01 | 2008-04-14 | 아스트라제네카 아베 | 흡입기 밸브 |
| GB0523654D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| GB0523655D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| GB0523656D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| NZ568349A (en) | 2005-12-21 | 2011-05-27 | Meda Pharma Gmbh & Co Kg | Combination of anticholinergics, glucocorticoids, beta2-agonists, PDE 4 inhibitor and antileukotriene for the treatment of inflammatory diseases |
| GB0613161D0 (en) | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
| EP1894568A1 (en) * | 2006-08-31 | 2008-03-05 | Novartis AG | Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases |
| US8618160B2 (en) | 2007-10-18 | 2013-12-31 | Rose U | Topical glycopyrrolate formulations |
| AU2010258751A1 (en) * | 2009-06-09 | 2012-02-02 | Sunovion Respiratory Development Inc. | Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration |
| ES2467928T3 (es) | 2009-12-23 | 2014-06-13 | Chiesi Farmaceutici S.P.A. | Formulación en aerosol para EPOC |
| MX340264B (es) * | 2009-12-23 | 2016-07-04 | Chiesi Farm Spa | Formulacion de aerosol para la enfermedad pulmonar obstructiva cronica. |
| ES2468835T3 (es) | 2009-12-23 | 2014-06-17 | Chiesi Farmaceutici S.P.A. | Terapia combinada para EPOC |
| CA2785321C (en) * | 2009-12-23 | 2018-08-21 | Chiesi Farmaceutici S.P.A. | Combination therapy for copd |
| PT3019153T (pt) * | 2013-07-11 | 2018-12-04 | Chiesi Farm Spa | Formulação de pó seco que compreende um anticolinérgico, um corticosteroide e um beta-adrenérgico para administração por inalação |
| ES2666905T4 (es) * | 2013-12-30 | 2018-06-07 | Chiesi Farmaceutici S.P.A. | Composición en solución para aerosol estable presurizada de una combinación de bromuro de glicopirronio y formoterol |
| SI3089735T1 (sl) * | 2013-12-30 | 2018-10-30 | Chiesi Farmaceutici S.P.A. | Sestavek stabilne aerosolne raztopine pod tlakom, ki vsebuje glikopironijev bromid in formoterol |
| US9554992B2 (en) * | 2014-06-09 | 2017-01-31 | Chiesi Farmaceutici S.P.A. | Inhalation particles comprising a combination of an anticholinergic, a corticosteroid and a beta-adrenergic |
| US10098837B2 (en) * | 2016-07-28 | 2018-10-16 | Chiesi Farmaceutici S.P.A. | Combination therapy for COPD |
-
2010
- 2010-12-22 CA CA2785321A patent/CA2785321C/en active Active
- 2010-12-22 TW TW099145166A patent/TWI495468B/zh active
- 2010-12-22 NZ NZ600790A patent/NZ600790A/en unknown
- 2010-12-22 JP JP2012545323A patent/JP5914354B2/ja active Active
- 2010-12-22 SI SI201030654T patent/SI2515855T1/sl unknown
- 2010-12-22 EA EA201590179A patent/EA027778B1/ru active Protection Beyond IP Right Term
- 2010-12-22 AU AU2010334859A patent/AU2010334859A1/en not_active Abandoned
- 2010-12-22 PL PL10799030.1T patent/PL2515855T6/pl unknown
- 2010-12-22 KR KR1020127015996A patent/KR101757951B1/ko active Active
- 2010-12-22 PT PT107990301T patent/PT2515855E/pt unknown
- 2010-12-22 AR ARP100104922A patent/AR079726A1/es not_active Application Discontinuation
- 2010-12-22 KR KR1020177009412A patent/KR20170040392A/ko not_active Ceased
- 2010-12-22 CN CN201410289445.6A patent/CN104055765B/zh active Active
- 2010-12-22 EP EP10799030.1A patent/EP2515855B3/en active Active
- 2010-12-22 PH PH1/2012/501066A patent/PH12012501066A1/en unknown
- 2010-12-22 WO PCT/EP2010/070479 patent/WO2011076843A2/en not_active Ceased
- 2010-12-22 EA EA201290375A patent/EA021917B1/ru active Protection Beyond IP Right Term
- 2010-12-22 DK DK10799030.1T patent/DK2515855T6/da active
- 2010-12-22 MX MX2012006878A patent/MX2012006878A/es active IP Right Grant
- 2010-12-22 BR BR112012015337A patent/BR112012015337B8/pt active IP Right Grant
- 2010-12-22 PE PE2012000865A patent/PE20121396A1/es not_active Application Discontinuation
- 2010-12-22 PE PE2016000787A patent/PE20160853A1/es unknown
- 2010-12-22 UA UAA201207626A patent/UA113832C2/uk unknown
- 2010-12-22 SG SG2012046157A patent/SG181868A1/en unknown
- 2010-12-22 CN CN201080058048.8A patent/CN102665679B/zh active Active
- 2010-12-22 ES ES10799030T patent/ES2468840T7/es active Active
- 2010-12-22 HR HRP20140582TT patent/HRP20140582T4/hr unknown
- 2010-12-22 GE GEAP201012756A patent/GEP20156311B/en unknown
- 2010-12-22 MY MYPI2012002844A patent/MY156949A/en unknown
- 2010-12-22 RS RS20140338A patent/RS53391B2/sr unknown
- 2010-12-23 US US12/977,159 patent/US20110150782A1/en not_active Abandoned
-
2012
- 2012-05-29 TN TNP2012000269A patent/TN2012000269A1/en unknown
- 2012-06-01 CO CO12092198A patent/CO6541628A2/es unknown
- 2012-06-14 MA MA34966A patent/MA33823B1/fr unknown
- 2012-06-21 CL CL2012001705A patent/CL2012001705A1/es unknown
- 2012-06-21 ZA ZA2012/04615A patent/ZA201204615B/en unknown
-
2014
- 2014-05-29 CY CY20141100382T patent/CY1115116T1/el unknown
-
2015
- 2015-07-29 US US14/812,190 patent/US10159645B2/en active Active
-
2016
- 2016-04-04 JP JP2016075136A patent/JP6283388B2/ja active Active
- 2016-09-27 AU AU2016234895A patent/AU2016234895B2/en active Active
-
2017
- 2017-12-22 CY CY2017047C patent/CY2017047I1/el unknown
- 2017-12-29 FI FIEP10799030.1T patent/FI2515855T6/fi active
- 2017-12-29 FI FIC20170064C patent/FIC20170064I1/fi unknown
-
2018
- 2018-01-05 HU HUS1800001C patent/HUS1800001I1/hu unknown
- 2018-01-10 NO NO2018001C patent/NO2018001I2/no unknown
- 2018-01-10 LU LU00060C patent/LUC00060I2/fr unknown
- 2018-01-11 LT LTPA2018001C patent/LTC2515855I2/lt unknown
- 2018-01-12 NL NL300923C patent/NL300923I2/en unknown
- 2018-04-30 AU AU2018202998A patent/AU2018202998A1/en not_active Abandoned
- 2018-08-01 IL IL260932A patent/IL260932B/en active IP Right Grant
- 2018-10-16 US US16/161,427 patent/US11389401B2/en active Active
-
2019
- 2019-08-02 AR ARP190102199A patent/AR115897A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW201129359A (en) | Pharmaceutical composition for the treatment of COPD | |
| WO2011076841A3 (en) | Combination therapy for copd | |
| MX340924B (es) | Composiciones farmaceuticas. | |
| WO2012016845A3 (en) | Pharmaceutical formulation comprising a phosphodiesterase inhibitor | |
| GEP20166479B (en) | Aerosol formulation for copd | |
| CO2022012449A2 (es) | Inhaladores dosificadores presurizados que comprenden una formulación farmacéutica amortiguada | |
| MX2014004364A (es) | Composiciones que comprenden sulfato de salbutamol. | |
| WO2014016548A3 (en) | Pharmaceutical composition comprising olodaterol and one or more further active pharmaceutical ingredient | |
| WO2012040228A3 (en) | Aerosol composition for administering drugs | |
| AR123674A2 (es) | Composición farmacéutica en aerosol de formoterol y dipropionato de beclometasona | |
| CL2023000998A1 (es) | Formulación farmacéutica para inhalador presurizado de dosis medidas | |
| WO2010042701A3 (en) | Corticosteroid compositions for use in treating diseases of the upper and lower airway passages | |
| NZ591174A (en) | Metered dose inhaler | |
| CL2012000947A1 (es) | Formulación en suspensión para inhalar de dosis medida que comprende fumarato de formoterol dihidratado y propionato de fluticasona y microlin sodico en un propelente hfa; composicion farmaceutica; un producto; uso de 0,01 a 0,1% cromolin sodico, util en asma y rinitis. | |
| MX2024014385A (es) | Formulacion farmaceutica para inhalador presurizado de dosis medidas | |
| TH127043A (th) | ผลิตภัณฑ์รวมสำหรับบำบัด copd | |
| BR102012008322B8 (pt) | formulações medicinais em aerossol que não debilitam a camada de ozônio e com baixo efeito estufa |