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NZ591174A - Metered dose inhaler - Google Patents

Metered dose inhaler

Info

Publication number
NZ591174A
NZ591174A NZ591174A NZ59117409A NZ591174A NZ 591174 A NZ591174 A NZ 591174A NZ 591174 A NZ591174 A NZ 591174A NZ 59117409 A NZ59117409 A NZ 59117409A NZ 591174 A NZ591174 A NZ 591174A
Authority
NZ
New Zealand
Prior art keywords
metered dose
inhaler
combination
canister
pmdi
Prior art date
Application number
NZ591174A
Inventor
John Hywel Davies
Original Assignee
Neo Inhalation Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39722250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ591174(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neo Inhalation Products Ltd filed Critical Neo Inhalation Products Ltd
Publication of NZ591174A publication Critical patent/NZ591174A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0073—Mechanical counters having a display or indicator on a ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0075—Mechanical counters having a display or indicator on a disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

591174 The present invention relates to metered dose inhalers for the administration of active medicaments/propellants and excipients from pressurised aerosol cans. The invention provides a pMDI inhaler (20) comprising a pMDI canister (22), a vortex device, an integral horn (58) and a breath-activated mechanism (26, 28, 34, 66, 78). The canister (22) contains a formulation comprising a combination of an inhaled corticosteroid (ICS) such as fluticasone and a long-acting beta-agonist (LABA) such as sameterol. The combination of the vortex inhaler (20) with the asthma medication results in an increased lung absorption of the respirable dose.
NZ591174A 2008-07-14 2009-07-14 Metered dose inhaler NZ591174A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0812854.8A GB2461752B (en) 2008-07-14 2008-07-14 Metered dose inhaler
PCT/GB2009/001740 WO2010007361A1 (en) 2008-07-14 2009-07-14 Metered dose inhaler

Publications (1)

Publication Number Publication Date
NZ591174A true NZ591174A (en) 2013-09-27

Family

ID=39722250

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ591174A NZ591174A (en) 2008-07-14 2009-07-14 Metered dose inhaler

Country Status (6)

Country Link
EP (1) EP2313113A1 (en)
CA (1) CA2734135C (en)
GB (1) GB2461752B (en)
NZ (1) NZ591174A (en)
WO (1) WO2010007361A1 (en)
ZA (1) ZA201101206B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2230934B8 (en) 2007-12-14 2012-10-24 AeroDesigns, Inc Delivering aerosolizable food products
JP4878651B1 (en) * 2010-09-17 2012-02-15 シャープ株式会社 Mobile station apparatus, communication system, communication method, and integrated circuit
GB201118845D0 (en) 2011-11-01 2011-12-14 Euro Celtique Sa Dispenser
EP2983773B1 (en) 2013-03-14 2018-03-07 Trudell Medical International Metered dose inhaler applicator
EP3247339A1 (en) * 2015-01-23 2017-11-29 Teva Branded Pharmaceutical Products R & D, Inc. An inhalable medicament
GB2544477A (en) * 2015-11-16 2017-05-24 3M Innovative Properties Co Improvements in or relating to medical actuators

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001730A1 (en) * 1984-09-18 1986-03-27 Vortran Corporation Aerosol producing device
EP0308524B1 (en) * 1987-09-22 1995-04-26 Vortran Medical Technology, Inc. Inhalation device and method
US4955371A (en) * 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
IL106930A0 (en) * 1992-09-08 1993-12-28 Norton Healthcare Ltd Medicament dispensing device
WO2001028887A1 (en) * 1999-10-16 2001-04-26 Glaxo Group Limited Device housing for an aerosol container
US6581590B1 (en) * 2000-03-21 2003-06-24 Iep Pharmaceutical Devices Inc. Inhalation actuated device
TWI224515B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
KR100947409B1 (en) * 2002-03-01 2010-03-12 키에시 파르마슈티시 엣스. 피. 에이. Formoterol Ultrafine Composition
SE0301426D0 (en) * 2003-05-15 2003-05-15 Astrazeneca Ab Novel treatment
US7600512B2 (en) * 2003-07-14 2009-10-13 Vortran Medical Technology 1, Inc. Inhaler with breath actuated dose counter
US7703454B2 (en) * 2003-07-14 2010-04-27 Vortran Medical Technology Inhaler with breath actuated dose counter
US7219664B2 (en) * 2005-04-28 2007-05-22 Kos Life Sciences, Inc. Breath actuated inhaler
GB0518770D0 (en) * 2005-09-14 2005-10-26 Glaxo Group Ltd A closure for a dispensing device
AR058290A1 (en) * 2005-12-12 2008-01-30 Glaxo Group Ltd MEDICINAL DISPENSER
GB0602897D0 (en) * 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
GB0611131D0 (en) * 2006-06-06 2006-07-19 Neo Inhalation Technologies Lt Nicotine inhalation therapies - smoking cessation and other medical uses
EP2142239B1 (en) * 2007-04-30 2017-06-07 Sun Pharma Advanced Research Company Limited Inhalation device

Also Published As

Publication number Publication date
EP2313113A1 (en) 2011-04-27
ZA201101206B (en) 2012-04-25
CA2734135A1 (en) 2010-01-21
GB2461752A (en) 2010-01-20
GB0812854D0 (en) 2008-08-20
WO2010007361A1 (en) 2010-01-21
CA2734135C (en) 2020-12-29
GB2461752B (en) 2013-04-17

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Legal Events

Date Code Title Description
RENP Pct: late entry into national phase requested

Effective date: 20110215

PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 14 JUL 2016 BY CPA GLOBAL

Effective date: 20140224

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 14 JUL 2019 BY CPA GLOBAL

Effective date: 20140903

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 14 JUL 2022 BY CPA GLOBAL

Effective date: 20140906

Free format text: PATENT RENEWED FOR 7 YEARS UNTIL 14 JUL 2029 BY CPA GLOBAL

Effective date: 20140908