TW200838428A - Pesticidally active compositions comprising 3-acetyl-1-phenylpyrazole compounds - Google Patents

Abstract

The present invention relates to pesticidal compositions comprising as active components at least one 3-acetyl-l-phenylpyrazole compound of the formula I or a salt thereof: wherein X is N or C-R5; R1 is C1-C4-alkyl or C1-C4-haloalkyl; R2 is NR6R7 or S(O)nR8; R3 is halogen, C1-C4-haloaikyl, C1-C4-haloaikoxy, SF5 or S(O)pR9; R4 is hydrogen or halogen; R5 is halogen; R6 is hydrogen, C1-C4-alkyl, C1-C4-haloalkyl, C(O)R10, S(O)qCF3; R7 is hydrogen or C1-C4-alkyl, or R6 and R7 are joined so as together form a C4-C6-alkylene moiety, wherein one CH2-group may be replaced by oxygen or a radical N-R11; R8, R9, R10, R11 are each independently hydrogen, C1-C4-alkyl or C1-C4-haloalkyl; m, n, p and q are each independently 0, 1 or 2; and at least one further pesticidally active compound II, selected from A.1 GABA-gated chloride channel antagonists; A.2 Nicotinic acetylcholine receptor agonists/antagonists A.3 Juvenile hormone mimics; A.4 Compounds affecting the oxidative phosphorylation; A.5 Inhibitors of the chitin biosynthesis; A.6 Moulting disruptors; A.7 Mitochondrial electron transport inhibitors; A.8 Voltage-dependent sodium channel blockers; A.9 Inhibitors of the lipid synthesis; and A.10 group of various compounds

Description

200838428 IX. INSTRUCTIONS OF THE INVENTION: TECHNICAL FIELD OF THE INVENTION The present invention relates to at least one 3-ethylamino-1-phenyl-pyridyl compound of the formula I or a salt thereof:

Wherein X is N or C-R5; ... is ^-sanalkyl or CVCU haloalkyl; R2 is NR6R7 or S(0)nR8; R3 is halogen, CVC4 haloalkyl, (ν(:4_alkoxy) , SF5 or S(0)pR9; R is chlorine or _; ;^5 is _; R is hydrogen, CrCU alkyl, CVCU halogen, c(〇)Ri〇, S(0)qCF3; R7 Is hydrogen or c--C4 alkyl, or "joined with !^ to form a C4_C6 alkyl group, wherein one CH2 group can be replaced by oxygen or a group of feet; R8 m π are each independently Hydrogen, Ci_C4 alkyl or c 128485.doc 200838428 Tooth burning base; P&q are each independently 0, 1 or 2; - Pesticide-active compound π as active ingredient pesticide [Prior Art] In the field of pest control The emergence of the typical problem in; ^ to reduce activity

The dose rate in t to reduce or avoid adverse environmental effects or toxicological effects while k still allows for effective pest control. Another problem encountered is the need for an available pest control agent that is effective against a wide range of pests. There is also a need for a pest control agent that combines strong activity with long-term control, that is, a combination of rapid action and long-lasting action.

m, η, and at least another composition. Another difficulty associated with the use of pesticides is the repetition and only—(iv) individual pesticide compounds result in a rapid selection of pests that have developed natural or adaptive resistance to the active compound 16 in question under various conditions. Therefore, there is a need for pest control agents that help prevent or overcome resistance. The compounds of formula I, their preparation and their action against arthropods, plant nematodes, creeps or protozoan pests have been described in Wq 98/2 8277. It has been suggested herein to combine Compound I with a synergist such as: piperonyl butoxide or sesamex, stabilizing substances, other insecticides, acaricides, plant-killing nematodes, worms Agents or anticoccidial agents, fungicides, fungicides, arthropod or vertebrate attractants or repellents, pheromones, fragrances, dyes or adjuvant therapeutics (such as trace elements). However, the composition comprising Compound I and at least one insecticide compound 128485.doc 200838428 is not specifically disclosed. In particular, 'w 98/28277 does not disclose that the inclusion of the compound I of the invention and at least one other compound „ has increased activity according to synergism, enhances the range of activity, combines potent activity with long-term control or applies to resistance management A pesticidal composition. Accordingly, it is an object of the present invention to provide a pesticidal composition that solves at least one of the problems discussed, such as reducing the dosage rate, enhancing the range of activity, or combining the potent activity with long-term control or for resistance management. SUMMARY OF THE INVENTION We have found that this object is achieved, in part or in whole, by a combination of at least one compound of the formula and at least one pesticidally active compound 选自 selected from Group A as defined below. Furthermore, we have found that simultaneously (ie Administration of compound I and one or more quinone compounds π or continuous administration of compound I and one or more group A compounds π enhances control of pests compared to possible control rates in the case of individual compounds The group A of the pesticide-active compound consists of the following: Α·1 is selected from the following GABA-gated types Ion channel antagonist A.la 1^-ethyl-2,2-methylpropyl S&amine 2-(2,6-dichloro-α·α·α-diox-p-methyl group) , N_ethyl-2,2-diqi-l-fluorenylcyclopropane-carbamidine-2-(2,6-dichloro-α·α·α_trifluoro-p-tolyl) hydrazine; Α· 1 .b from ethiprole, fipronil, pyrafluprole, pyripr〇le, vaniliprole and phenylpyrazole compounds Category of phenylpyrazole consisting of π·A2·1: 128485.doc -10- 200838428

Α·2 is a nicotinic acetylcholine receptor agonist/antagonist selected from the group consisting of nicotin, thiocyclam, acetamiprid, and chlorpyrifos ( Similar to neonicotinoid consisting of chlothianidin, dinotefliran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam and AKD-1022 And ectopic nicotinic acetylcholine receptor agonist spinosad; A.3 a juvenile hormone selected from the group consisting of: hydroprene, aphid _ (kinoprene), Fenoke (€611 father 5^&1^) and pyriproxyfen; Α·4 is selected from the following compounds that affect oxidative phosphorylation: diafenthiuron ), fenbutatin oxide, propargite, and chlorfenapyr; A.5 is a chitin biosynthesis inhibitor selected from the group consisting of buprofezin and Bistrifluron, diflubenzuron, flufenoxuron, hexaflumuron, lufenlong Benzylurea consisting of ufenuron) and novaluron; 128485.doc 11 200838428 Α·6 is selected from the following sclerosing agents: cyromazine and methoxyfenozide And the ecdysone agonist class composed of tebuferxozide; A.7 mitochondrial electron transport inhibitors selected from the group consisting of pyridaben, tolfenpyrad and Flufenerim; Α·8 is selected from the group consisting of indoxacarb and metaflumizone voltage-dependent sodium channel blockers; Α·9 is selected from the following lipid synthesis inhibitors: Spirodiclofen, spiromesifen, and spirotetramat; Α·10 A group of compounds consisting of the following compounds: amidoflumet, amitraz , bifenazate, clofentezine, cyenopyrafen, cyflumetofen, etoxazole, flubendiamide, fluoride brigade 11 flupyrazophos, hexythiazox, genital Pymetrozine, pyridalyl and pyrifluquinazon. Accordingly, the present invention relates to a pesticide comprising at least one 3-ethylindenyl-1-phenylpyrazole compound of the formula I or a salt thereof and at least one compound of the group A having a pesticidal activity as defined herein as an active ingredient. combination. The invention also provides a method for controlling insects, acarids or nematodes comprising contacting an insect, aphid or nematode or a food source, habitat, breeding ground or locus thereof with a pesticidally effective amount of a composition as defined herein. In addition, the present invention also relates to a method for protecting plants from insects, mites or invasive or infested by the worms of 128485.doc -12-200838428, which comprises a plant or plant growing soil or water 舆 pesticide effective amount as defined herein The composition is in contact. The invention also provides a method for protecting seeds from soil insects and protecting seedling roots and shoots from soil and leaf-feeding insects, comprising the effective amount of seeds and pesticides before and/or after germination. The defined composition is in contact. The invention also relates to the use of a composition as defined herein for combating arthropod pests, such as insects or arachnids, or nematodes. Compounds of Group A are commercially available compounds and are disclosed in particular in the Pesticide Manual, 13th Edition, British Crop Protection Council (2003). Thioamide derivatives analogous to formula II.A2.1 and their preparation have been described in WO 98/28279. Metaflumizone and its preparation are described in EP-A1 462 456. Flupyrazofos is described in Pesticide Science 54, 1988, pages 237-243 and US 4,822,779. Piperelol and its preparation have been described in JP-A 2002-193709 and WO 01/00614. Piperid and its preparation are described in WO 98/45274 and US 6,335,357. Indoleamine and its preparation have been described in US 6,221,890 and JP-A 21010907. Flufenillin and its preparation have been described in WO 03/007717 and WO 03/007718. Tetfluramine and its preparation have been described in WO 04/080180. A method for the preparation of neonicotinoid analogs similar to AKD-1022 has been described by Zhang, A. et al., J. Neurochemistry, 75(3), 2000. The organic moiety referred to in the above definitions of such codes is, for example, the term 128485.doc -13- 200838428 halogen, a collective term for individual lists of individual group members. In each case, the prefix cn-cm indicates the number of possible carbon atoms in the group. "π halogen" shall be taken to mean fluoro, chloro, bromo and iodo. The term "CKC4 alkyl" or "C1c2 alkyl" as used herein means having 1 to 4 or 1 or 2 carbon atoms, respectively. Branched or unbranched (linear) saturated hydrocarbon groups such as methyl, ethyl, propyl, ! Methyl ethyl, butyl, methylpropyl, 2-methylpropyl, dimethylethyl. The term "CVC4 haloalkyl π or decylalkyl" as used herein refers to a straight or branched alkyl group having 1 to 4 or 2 or 2 carbon atoms (as mentioned above) where Some or all of the hydrogen atoms in the group are replaced by a halogen atom as mentioned above, in particular by a fluorine atom or a chlorine atom, for example, a chloromethyl group, a dichloromethyl group, a trichloromethane group, a fluorine group. Base, dimethoxymethyl, trifluoromethyl, chlorofluoromethyl, difluorofluoromethyl, chlorodifluorodecyl, b-ethyl, 1-bromoethyl, b-fluoroethyl, 2-fluoroethyl , 2,2-difluoroethyl, 2,2,2-tri-Iethyl, ethyl, 2-chloro-2,2-diethylene, 2,2-di-I-fluoroethyl, 2, 2,2-trichloroethyl and pentafluoroethyl, 2-fluoroclay 3 I propyl, 2,2-difluoropropyl, 2,3-di-propyl propyl, 2- chloropropene 3 chloropropyl , 2,3_dichloropropyl, 2·propyl, 3_glypropyl, 3,3,3β-trifluoropropyl, 3,3,3-trichloropropyl, CH2-C2F5, CF2-C2F5 , CF(CF3)2, ^(fluorodecylfluoroethyl, 1-(chloromethyl)-2-chloroethyl, bromomethylethyl, 4-fluorobutyl, 4-chlorobutyl, 'mute butyl, nonafluorobutyl. Therefore, terminology, Ci -C2 fluoroalkyl" means a fluorenyl or ethyl group in which the i, 2, 3, 4 or 5 hydrogen atom has been replaced by fluorinated fluorine, such as in the fluoroindolyl group, the difluoromethyl group and the trifluoromethyl group. 128485.doc - 14- 200838428 Similarly '"CpC:4 alkoxy'' means a straight or branched alkyl group having 1 to 4 carbon atoms (as mentioned above) which is via an oxygen at any bond in the alkyl group. Keys are bonded. Examples include Ci_c4 alkoxylates such as methoxy, ethoxy, propoxy, isopropoxy, butoxy, second butoxy, isobutoxy and tert-butoxy base.

Similarly, "CrC: 4-haloalkoxy" refers to a straight or branched alkyl group having 1 to 4 carbon atoms (as mentioned above) which is bonded via an oxygen atom at any bond in the alkyl group. Wherein some or all of the hydrogen atoms of the groups are replaced by a halogen atom as mentioned above, in particular by a fluorine atom or a gas atom, for example a C1_C2 haloalkoxy group, such as chloromethoxy, bromomethoxy, Dichloromethoxy, trichloromethoxy, methoxymethoxy, difluoromethoxy, trifluoromethoxy, chloromethoxy, di methoxy, chlorodifluoromethoxy, 1-chloro Ethoxy, i. oxaoxyl fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2- Gas ethoxy, 2-chloro-2, 2_ bis ethoxy, 2,2. dichlorofluoroethoxy, 2,2,2·trichloroethoxy and pentafluoroethoxy and the like The compound I may be present in a neutral form or in the form of a salt thereof. Suitable salt 2 has no adverse effect on the action of the compound of the invention on its anthracene: an acid addition salt of an acid acceptable for the industry. The ions of the acid addition salt are mainly chloride ions, (tetra), Fluoride, hydrogen sulfate: sulphide, = acid dihydrogen, hydrogen phosphate, phosphate, nitrate, carbonate, carbonate, hexafluoride, hexafluorosilicate, benzoate and (c4 burn) An anion of an acid, preferably a formate, an acetate, a propionate or a butane. It can be obtained by using a compound of the formula: and an acid of the corresponding anion, preferably nitrogen 128485.doc -15- 200838428 acid, hydrobromic acid, sulfuric acid And squaric acid or nitric acid is formed by reacting. With regard to its use in the pesticidal composition of the present invention, a 3-ethylmercaptophenylpyrazole compound of the formula I is particularly preferred, wherein the codes of the individual or in particular combinations have the following meanings. X is N or preferably c_R5; m is 0 or 1; R1 is methyl; R2 is NR6R7'. wherein R6 and R7 are as defined above and wherein... especially selected from the group consisting of: a Ci_C2 alkyl group, a halogenated group C(〇)CH3 and s(o)2cf3, more preferably hydrogen; and wherein &amp;7 is especially selected from hydrogen or a Cl-C2 alkyl group, more preferably hydrogen, or a group _r6r7 Polinolin 1 is more than a pyridyl group, a benzylidene group, a 1-benzinyl group or a 4-methylpiperazin-1-yl group; R3 is a nutrient or 〇^2 tooth-burning group, preferably W_C2 oxygen a radical, especially a trifluoromethyl group; r4 is a halogen, especially chlorine; r5 is a halogen, especially chlorine. Particularly preferred are the compounds of the formula I and their salts, in which X is C-R5; m is 〇 or 1; Is methyl; R2 is nh2; R3 is _ or <^_〇: 2 fluoroalkyl; r4 is halogen, especially chlorine; and 128485.doc -16 - 200838428 r5 is halogen, especially chlorine. In a preferred embodiment, the formula is acetamidine (caffe oil), which corresponds to X being C-R5, i, Ri is a sulfhydryl group, r^Nh2, r3 is a trifluoromethyl group, and R4 is chlorine and R5 is a compound of the formula of chlorine. With respect to its use in the pesticide mixture of the present invention, 'the compound Η as listed in the following paragraphs is particularly preferred. A first embodiment of the invention relates to a pesticide composition comprising at least one compound of the group Α.1 as defined above and especially selected from the group of compounds Αι. Preferably, the compound Ai is selected from the group consisting of: N_ethyl-2,2-dimethylpropionamide_2_(2,6-dichloro-α.αα_trifluoro · p-Phenylphenyl) hydrazine, hydrazine-ethyl-2,2-dichloromethylcyclopropane-formamide-2_ (2,6-dichloro-α·α·α-trifluoro-p-tolyl)腙, 乙醯普, 乙虫清, fipronil, piperacop, piperid, Fan Li popular phenyl carbazole compound ΙΙ.Α2·1. More preferably, the compound A1 is selected from the group consisting of the following: ^^ethyl-['-monomethylpropionamide^^^-dichloro-[-trifluoro-p-tolyl) oxime and N-ethyl-2,2-dichloro-1-methylcyclopropane monomethanolamine 2_(2,6-dichloro-α.α·α_trifluoro-p-tolyl) oxime. More preferably, the compound A1 is selected from the group consisting of fipronil and acetaminophen. An example of the invention relates to a compound Ij [a pesticide composition comprising at least one compound of the group 2 as defined above and especially selected from the group of compounds Α·2. Wherein 'preferably, the compound Α·2 is selected from the group consisting of: insecticidal ring, acetamiprid, chlorothiazide, dinotefuran, idadamine, imidacloprid, thiacloprid, Thiamethoxam, AKD-1022 and spinosyn, especially clothianidin, edetamine, thiamethoxam, especially edaramin and thiazide 128485.doc -17- 200838428 嗓. The second embodiment of the present invention relates to a pesticide composition comprising at least one compound of the group 4 as defined above and especially selected from the group of compounds Α·4. Among them, the compound Α·4 is preferably a composition of the same. • A fourth embodiment of the invention relates to a pesticide composition comprising at least one compound of the group 5 as defined above and in particular selected from the group of compounds Α·5. Among them, the compound Α·5 is preferably a composition of the same. The present invention is directed to a pesticide composition comprising at least one compound of the group 7 as defined above and especially selected from the group of compounds Α7. Among them, it is preferred that the compound Α·7 is a composition of saponin or flufenaline. A sixth embodiment of the present invention relates to a pesticide composition comprising at least one compound of the above-described group of 8 groups and especially selected from the group of compounds Α8. Among them, it is preferred that the compound Α·8 is indoxacarb or cyanofluorfen, and in particular, the composition of mersin. • A seventh embodiment of the invention relates to a pesticide composition comprising at least one compound of the group 9 as defined above and especially selected from the group of compounds Α·9. Among them, it is preferred that the compound α·9 is selected from the group consisting of spirodecyl ester, spiromethyl ester and spirotetramat, especially selected from the group consisting of spiromethyl ester and spirotetramat. An eighth embodiment of the present invention relates to a pesticidal composition comprising at least one compound of the above group, and especially selected from the group of the compounds Al 。. Among them, it is preferred that the compound A1 is selected from the group consisting of triterpenoids, flufenamide, chlorpyrifos, acetamiprid and piperazine. Among them, 128485.doc -18- 200838428 is preferably a composition of the compound Α·10 which is a combination of chlorhexidine or piperazine. Particularly preferred is a pesticide containing bismuth-ethyl-2,2-dimethylpropionamide-2-(2,6-dichloro-α.α.α-trifluoro-p-tolyl) oxime as compound II. combination. It is especially preferred to contain 1^-ethyl-2,2-dichloro-1-methylcyclopropane-carbenamide-2-(2,6-dichloro-α.α.α-trifluoro-p-toluene A pesticide composition as a compound. Particularly preferred is a pesticidal composition containing fipronil as the compound II. Particularly preferred is a pesticidal composition containing acetaminophen as the compound II. Particularly preferred is a pesticidal composition containing cotinine as the compound II. Especially preferred is a pesticidal composition containing edaamine as compound II. Especially preferred is a pesticidal composition containing thiamethoxam as compound II. Particularly preferred is a pesticidal composition containing acetamiprid as the compound II. Particularly preferred is a pesticidal composition containing aspartate as the compound II. Especially preferred is a pesticidal composition containing buffing as a compound II. Particularly preferred is a pesticidal composition containing bismuth as a compound II. Particularly preferred is a pesticidal composition containing flufensulfine as the compound II. Particularly preferred is a pesticidal composition containing fluoranthene as the compound II. Particularly preferred is a pesticidal composition containing the compound as the compound II. Particularly preferred is a pesticidal composition containing spironolactone as the compound II. Particularly preferred is a pesticidal composition containing spirotetramat as the compound II. Particularly preferred is a pesticidal composition containing piperoxyquinone as the compound II. It is especially preferred that the compound II is fipronil and the compound of the formula I is an agrochemical composition of acetaminophen. It is especially preferred that the compound II is acetaminophen and the compound of the formula I is a pharmaceutical composition of acetaminophen 128485.doc -19- 200838428. It is especially preferred that the compound 11 is N_ethyl·2,2-dimethylpropionamide_2_(2,6-dichloro-α·α·α·tri-p-tolyl) The substance is a pesticide composition of acetaminophen. Particularly preferred is a compound 11 wherein the compound 11 is decyl 2,2-dichloromethylcyclopropan-2-carbamimid-2-(2,6-dichloroTM-trifluoro-p-methyl) and The compound of formula 1 is a pesticide composition of acetamidine.

It is especially preferred that the compound U is a nicotine and the compound of the formula is an agrochemical composition of acetaminophen. Preferably, the compound hydrazine is edaramine and the hydrazine compound is an agricultural composition of acetamidine. It is especially preferred that the compound II is thiamethoxam and the compound of the formula is an agricultural composition of acetaminophen. It is especially preferred that the compound II is a derivative and the compound of the formula is an agrochemical composition of acetaminophen. It is especially preferred that the compound II is fenfen and the compound of the formula is an agricultural composition of acetaminophen. It is especially preferred that the compound π is buffin and the compound of the formula is an amphetamine composition. It is especially preferred that the compound II is a quinone and a formula; [the compound is an agricultural composition of acetaminophen. It is especially preferred that the compound II is flufensulfonate and the hydrazine compound is an agricultural composition of acetamidine. It is especially preferred that the compound II is cyanofluorfen and the compound of the formula is acetylidene 128485.doc -20- 200838428 a pesticide composition. It is especially preferred that the compound II is a spiromethyl hydrazide and the compound of the formula I is a pesticide composition of acetaminophen. It is especially preferred that the compound II is spirotetramat and the compound of the formula I is a pesticide composition of acetaminophen. It is especially preferred that the compound π is piperazine and the compound of formula I is a pesticide composition of acetamidine. Another aspect of the present invention is that, in the preparation of the compositions, it is preferred to use the pure W active compounds I and II, to which other active compounds (for example, resistant to harmful fungi or herbicidal active compounds) or Growth regulator or fertilizer. The compositions of the present invention may contain both Compounds I and II or Compounds I and II may be administered simultaneously (i.e., in combination or separately) to exhibit significant resistance to pests. The composition is especially suitable for combating pests from the following species: insects from the order Lepidopterans (Lepidoptera), such as • Agrotis ypsilon, Agrotis segetum, Alabama argillacea , Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Hou Huang, Cacoecia murinana, cotton brown Capua reticulana, Cheimatobia brumata, Choristoneura fiimiferana, Western spruce leaf butterfly (€:11〇1^1:〇1^1^〇( :(^(161^&amp;118), American mites (Ciiphis unipuncta), Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, giant 128485.doc -21- 200838428

Diatraea grandiosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholitha funebrana, Grapholithas molesta, Heliothis armigera, Heliothis virescens, Heliothis zea, and vegetable fillets (Hellula undalis), Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina flscellaria, beet night Mophy (Laphygma exigua), Lepuoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, yellow-green scorpion (Loxostege sticticalis), lymantria dispar, nymphal moth (Lymantria mo Nacha), Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea ), red bollworm (?6 also! 1 (^11〇瓜8〇88}^611&amp;), variegated tiger (Peridroma saucia), Phalera bucephala, horse 钤 potato tuber moth (Phthorimaea Operculella), Phyllocnistis citrella, Pieris brassicae, Plathy penna scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia 128485.doc -22- 200838428 frustrana), Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, grass worm (8卩〇(1〇口161&amp; 1^1卩61' (1&amp;), Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, and green leaf moth ( Tortrix viridana), Trichoplusia ni and Zeiraphera canadensis,

Aphids (Coleoptera, Coleoptera), such as Agrihis sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar , Anthonomus grandis, Anthonomus pomorum, Aphthona euphoridae, Athous haemorrhoidalis, Atomaria linearis, Blastophagus Piniperda), Blitophaga undata, Brnchus rufimanus, Bmchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa ), Cerotoma trifurcata, Cetonia aurata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus Vespertinus), Crioceris asparagi, Ctenicera ssp·, Longhorned beetle Diabrotica longicornis), Diabrotica semipunctata, Diabrotica 12-punctata, Diabrotica speciosa, 128485.doc -23- 200838428 Diabrotica virgifera , Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, pine weevil (1^1〇1^118 abietis), Egyptian Hypora brunneipennis, eucalyptus (Hypera postica), Ips typographies, Lembilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius

Califomicus), Lisorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melonontha melolontha, rice Oulema oryzae, Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllobius pyri, Phyllotreta chrysocephala , Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, cowpea leaf 曱(Sitona lineatus) and Sitophilus granaria, ropes, mosquitoes (Diptera), such as Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles cruci Ans), Anopheles albimamis, Anopheles gambiae, Anopheles freeborni, Anopheles sinensis 128485.doc -24- 200838428

(Anopheles leucosphyms), Anopheles mini-mus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, America Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola, Cordylobia anthropophaga, Culicoides forens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus ), Culex tarsalis, Culiseta inornata, Culiseta melanura, Dacus cucurbitae, Dacus oleae, Brassica Dasineura brassicae, Delia antique, Delia coarctata, Delia platura, Gan Delia radicum, Dermatobia hominis, Fannia canicularis, Geomyza Tripunctata, Gasterophilus intestinalis, Glossina morsitans Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp. Hylemyia platura, Hypoderma lineata, Leptoconops torrens, Liriomyza sativae, Liriomyza trifolii, Mountain 128485.doc -25- 200838428

Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansonia titillanus, Mayetiola destructor ), Musca domestica, Muscina stabulans, Oestrus ovis, black-and-white cans (0卩〇111}^&amp; florum), Swedish straw rope (Oscinella frit), Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Phlebotomus argentipes, Psorophora columbiae, carrot rope (Psila rosae), Psorophora discolor, Prosimulium mixtum, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga haemorrhoidalis, Sarcophaga Sp·), Simulium vittatum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Taban Us lineola) and itan (Tabanus similis), cabbage (Tipula oleracea) and European mosquito (Tipula paludosa), thrips (Thysanoptera), such as orchid thrips (Dichromothrips corbetti), orchid Dichromothrips spp., Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae ), Thrips palmi and Thrips tabaci, termites (Isoptera), such as European wood termites (Calotermes 128485.doc -26- 200838428 flavicollis), yellow foot termites (Leucotermes flavipes) ), heterotermes aureus, Reticulitermes flavipes, Reticulitermes virginicus, Reticulitermes lucifugus, Termes natalensis, and Taiwan milk white sacrifice ( Coptotermes formosanus),

蟑螂 (Blattaria-Blattodea), such as Blattella germanica, Blattella asahinae, American cockroach (〇11卩1&amp;1^&amp;&amp;11161^ dish), 曰Benedict (?61^1&amp;]16 words 3]3卩0111.&amp;), brown pheasant (Periplaneta brunnea), black-breasted cockroach (Periplaneta fuligginosa), Australian cockroach (Periplaneta australasiae) and oriental non-蠊(Blatta orientalis), True bug (Hemiptera), such as Acrosternum hilare, Blissus leucopterus, Cyrtopeltis notatus, cotton red mites (Cyrto orientalis) Dysdercus cingulatus), Dysdercus intermedius, Eurygasterintegriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, pasture blinding Lygus pratensis), Nezara viridula, Piesema quadrata, Solubea insularis, Thyanta perditor, cowpea pair (Acyrthosiphon o Nobrychis), Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis forbesi, Aphis pomi, Aphis gossypii, vinegar Aphis grossulariae, buckthorn (Aphis 128485.doc •27- 200838428

Schneideri), Aphis spiraecola, Aphis sambuei, Acyrthosiphon pisum, Aulacorthum solani, Bemisia argentifolii, Short-tailed worm (Brachycaudus cardui), Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brevicoryne brassicae, Capitophorus horni, Cotton worm (Cerosipha gossypii) ), Chaetosiphon fragaefolii, Cryptomyzusribis, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, apple ditch Dysaulacorthum pseudosolani, Dysaphis plantaginea, Dysaphis pyri, Empoasca fabae, Hyalopterus prnni, and sorrel Hyperomyzus lactucae), Macrosiphum avenae, scorpion (Macrosiphum euphorbiae), Macrosiphon rosae, Megoura viciae, Melanaphis pyrarius, Metopolophium dirhodum, Myzus persicae, Winter onion 1 (Myzus ascalonicus), Myzus cerasi, Myzus varians, Nasonovia ribis-nigri, Nilaparvata lugens, Pemphigus Bursarius), Perkinsiella saccharicida, Phorodon humuli, Pingmu Yan (? 3}^1^11^1〗), Psylla piri, winter onions! Rhopalomyzus ascalonicus, jade 128485.doc -28- 200838428

Rhopalosiphum maidis, Rhopalosiphum padi, Rhopalosiphum insertum, Sappaphis mala, Sappaphis mali, maidenworm teeth (Sappaphis mali) Schizaphis graminum), Schizoneura lanuginosa, Sitobion avenae, trialeurodes vaporariorum, Toxoptera aurantiiand, Viteus vitifolii, temperate bed bug (Cimex) Lectularius), tropical bedbugs ((1^111^1^1111卩1^1:118), old-fashioned Reduvius senilis, Triatoma spp., and Arilus critatus, Ants, bees, wasps, leaf bees (Hymenoptera, hymenoptera), such as Athalia rosae, Atta cephalotes, Atta capiguara, and big-headed ants Atta cephalotes), Atta laevigata, Atta robusta, Atta sexdens, Atta texana Crematogaster spp., Hoplocampa minuta, Hoplocampa testudinea, Monomorium pharaonis, Solenopsis geminata, Solenopsis invicta, fire Ants (8〇1611〇卩818 richteri), California fire ants (Solenopsis xyloni), red harvest ants (Pogonomyrmex barbatus), California harvest ants (Pogonomyrmex californicus), Pheidole megacephala, Dasymutilla occidentalis, Bumblebee Genus (Bombus spp.), Southern Hornet (Vespulasquamosa), Pair of Vespa (Paravespula vulgaris), Bin 128485.doc -29- 200838428 State vs. Yellow Vespa (Paravespula pennsylvanica), German vs. Yellow Vespa (Paravespula germanica), Bald Face For the hornet (Dolichovespula maculata), the European hornet (Vespa crabro), the Polistes rubiginosa, the Camponotus floridanus and the Linepithema humile,

蟠蟀, 蚱猛, 4 king Orthoptera (Orthoptera), such as Acheta domestica, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femurmbmm, Melanoplus mexicanus, migratory savage (1\^1 mad 11〇卩1118 8311 101^068), Melanoplus spretus, red-winged worm Nomadacris septemfasciata, Schistocerca americana, Schistocerca gregaria, Dociostaurus maroccanus, Tachycines asynamorus, Senegalese car worm (Oedaleus senegalensis), Zonozerus variegatus, Hieroglyphus daganensis, Kraussaria angulifera, Calliptamus italicus, Chortoicetes terminifera and South Africa Locustana pardalina, Arachnoidea, such as the arachnid (Acarina), Such as Argasidae, Ixodidae and Sarcopteridae, such as Amblyomma americanimi, Amblyomma variegatum, Ambryomma maculatum, Persian Arg (Argas persicus), 128485.doc -30- 200838428

Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Dermacentor silvamm, Dermacentor andersoni, Dermacentor variabilis ), long-stained eyelids (Hyalomma truncatum), Ixodes ricinus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Pacific hard palate (Ixodes holocyclus) Ixodes pacificus), σ彖蜱 (Ornithodorus moubata), Ornithodorus hermsi, Ornithodorus turicata, Ornithonyssus bacoti, 17 耳 (Otobius megnini) ), Dermanyssus gallinae, Psoroptes ovis, Rhipicephalus sanguineus, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei And Eriophyidae spp., such as Aculus schlechtendali, Phyllocoptrata oleivora Eriophyes sheldoni; Tarsonemidae spp., such as Phytonemus pallidus and Polyphagotarsonemus latus; Tenuipalpidae spp. Such as, for example, Brevipalpus phoenicis; Tetranychidae spp., such as Tetranychus cinnabarinus, Tetranychus kanzawai, Tettranychus pacificus, cotton red worm (Tetranychus telarius) and Tetranychus urticae, Panonychus ulmi, Panonychus citri and grass 128485.doc -31- 200838428 Earthworm (oligonychus pratensis); Latrodectus mactans and Loxosceles reclusa, fleas (Siphonaptera) ' For example! Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus fasciatus, aphids, Domestic fish (Thysanura), such as Lepisma saccharina and Thermobia domestica,

Chilopoda, such as Scutigera coleoptrata, Polypodidae, such as the genus Narceus spp., worms (Lepidoptera, Dermaptera) ), for example, Forflcula auricularia 5 (Phthiraptera), such as Pediculus humanus capitis, human nitrogen (Pediculus humanus corporis), Pthirus pubis, cattle Bled (Haematopinus eurysternus), Haematopinus suis, Linognathus vituli, Bovicola bovis, Menopon gallinae, Menacanthus stramineus and cattle Solenopotes capillatus, plant parasitic nematodes, such as root-knot nematodes, Meloidogyne arenaria, Meloidogyne chitwoodi, Meloidogyne exigua, northern root 128485.doc -32- 200838428

Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica and other root-knot nematodes; cyst nematodes, Globodera rostochiensis, potato cyst nematode ( Globodera pallida), Globodera tabacum and other cyst nematodes, Heterodera avenae, Heterodera glycines, Heterodera schachtii, clover cysts Nematodes (116161&gt;〇(161^11^〇出); and other cyst nematodes; species nematodes, Anguina funesta, Anguina tritici, and other nematodes; Stem and leaf nematodes, Aphelenchoides besseyi, Aphelenchoides fragariae, Aphelenchoides ritzemabosi and other species of the genus Nematodes; Nematodes, A. elegans (Belonolaimus) Longicaudatus and other species of the genus Nematode; pine worm, pine wood nematode (Bursaphelenchus xylophil Us) and other pine wood nematodes; ring nematodes, Criconema species, Criconemella species, Criconemoides species, and Mesocriconema species; bulb nematodes , Ditylenchus destructor, Ditylenchus dipsaci, Ditylenchus myceliophagus and other stem nematodes; cone nematodes, Dolichodorus species; spiral nematodes, double palaces Helicover (Helicotylenchus dihystera), Helicotylenchus multicinctus and others 128485.doc -33- 200838428

Spirulina species, Rotylenchus robustus and other species of H. elegans; Nematodes, Hemicycliophora species and Hemicriconemoides species; Hirshmanniella species; Species, Hoplolaimus columbus, Hoplolaimus galeatus and other crownworm species; pseudo-root nodule, Nacobbus aberrans and other pearl line species; needle nematodes, Longidorus elongates And other species of long needle nematodes; Nematodes, Paratylenchus species; rot nematodes, Pratylenchus brachyurus, Pratylenchus coffeae, Pratylenchus curvitatus, Ancient Rattynchus goodeyi, Pratylencus neglectus, Pratylenchus penetrans, Pratylenchus scribneri, Pratylenchus vulnus , short-tailed nematode (Pratylenchus zeae) and Short-line nematode species; Rhadinaphelenchus cocophilus and other species of nematodes; similar perforated nematodes, Radopholus similis and other perforated nematodes; nematode nematodes, nematodes (Rotylenchulus reniformis) and other nematode species; Shield nematodes; C. elegans, Trichodorus primitivus and other burrowing nematodes; Pseudostellaria and other genus Trichinella; Dwarf nematodes, tobacco dwarf Nematodes (Tylenchorhynchus claytoni), indefinite dwarf nematodes (Tylenchorhynchus dubius) and other dwarf nematodes and short-toothed Merlin 128485.doc -34- 200838428 Merlinius species; Hanging nematodes, hanging orange half-trapping nematodes (Tylenchulus semipenetrans) and other citrus nematodes; S. elegans, Xiphinema americanum, Xiphinema index, Xiphinema diversicaudatum, and other species of nematodes, and other plant-parasitic nematodes. Further, the pesticidal composition of the present invention is particularly useful for controlling Lepidoptera, Coleoptera, Diptera, Thysanoptera, and Hymenoptera. The pesticidal compositions of the present invention are particularly useful for controlling Thysanoptera and Hymenoptera, especially Hymenoptera.

The pesticidal compositions of the present invention can be converted into conventional formulations such as solutions, emulsions, suspensions, powders, powders, pastes and granules. The form of use will depend on the particular purpose desired; in each case, it should be ensured that the compounds used in accordance with the invention are finely and uniformly distributed.

In a known manner (see, for example, US 3,060,084, EP-A 707 445 (for liquid concentrates), Browning, &quot; Agglomeration' Chemical Engineering, December 4, 1967, 147-48, Perry's Chemical Engineer's Handbook, 4th , McGraw-Hill, New York, 1963, pp. 8-57 and WO 91/13546, US 4,172,714 'US 4,144,050, US 3,920,442, US 5,180,587, US 5,232,701, US 5,208,030, GB 2,095,558, US 3,299,566, Klingman, Weed Control as a Science, John Wiley and Sons, Inc., New York, 1961, Hance et al, Weed Control Handbook, 8th edition, Blackwell Scientific Publications, Oxford, 1989 and Mollet, H., Grubemann , A·, Formulation technology, Wiley VCH Verlag GmbH, Weinheim 128485.doc -35- 200838428 (Germany), 2001, 2. D. A. Knowles, Chemistry and Technology of Agrochemical Formulations, Kluwer Academic Publishers, Dordrecht, 1998 (ISBN 0-7514_0443_8)), for example by using an auxiliary agent (such as a solvent and/or a carrier) suitable for blending agrochemicals, if necessary • of agents, surfactants and dispersants, preservatives, antifoaming agents, antifreeze agents, • prepared for seed treatment formulations are formulations should also optionally gelling agents) expansion of the active compound. Φ In general, in addition to at least one compound of the formula I and one or more compounds II, the formulation of the drug or slave parasite also comprises a liquid or solid carrier and optionally other auxiliaries, such as emulsifiers, surfactants and Dispersing agents, preservatives, antifoaming agents, antifreeze agents, and gelling agents are also optionally included in the seed treatment formulation. Liquid carriers include conventional solvents. Examples of suitable solvents are water, aromatic solvents (eg, solvesso products, xylene), paraffins (eg, mineral oil fractions), alcohols (eg, methanol, butanol, pentanol, succinyl alcohol), ketones (eg, , cyclohexanone, butyrolactone), pyrrole ketone (NMP (N•methyl·pyrrolidone), nop (n-octyl·anthrolidone)), acetate (ethylene glycol diethyl Acid esters), glycols, fatty acid dimethyl decylamine, fatty acids and fatty acid esters. Solvent mixtures can also be used in principle. Suitable emulsifiers are nonionic and anionic emulsifiers (for example, poly-ethylene oxide fatty alcohol ethers, alkyl sulfonates and aryl sulfonates). Examples of sub-governing agents are lignin-sulfite waste liquid and methyl cellulose. Suitable surfactants used are lignosulfonic acid, naphthalenesulfonic acid, phenolic acid, alkali metal salts of dibutylnaphthalenesulfonic acid, alkaline earth metal salts and ammonium salts, alkylarylsulfonates, alkyl sulfates, and alkane. Sulfonate, fatty alcohol sulfate 128485.doc -36 - 200838428

Fatty acid and sulfated fatty alcohol glycol ether, in addition, condensed product of sulfonated naphthalene and naphthalene derivative with methylate, naphthalene or naphthalene; condensate of acid and benzene and carbaryl, polyepoxyoctyl octyl Phenylene ether, ethoxylated isooctylbenzene, octyl benzene, mercapto benzene, alkyl benzene (tetra) glycol ether 'tributyl phenyl polyethylene glycol scale, tristearic acid benzene Polyethylene aryl aryl group, alcohol and fatty alcohol epoxy condensate condensate, ethoxylated E sesame oil, polyepoxyethylene group, ethoxylated polyoxypropylene, lauryl polyethylene glycol (4) Laying, sorbitol vinegar, wood sulfite waste liquid and sulfhydryl cellulose. Suitable for preparing a directly sprayable solution, emulsion, paste or oily dispersion, which is a mineral oil with a medium to high point, such as kerosene or diesel, in addition to coal tar and oil of plant or animal origin, Aliphatic hydrocarbons, cyclic hydrocarbons and aromatic hydrocarbons (for example, alpha 1, bisbenzene, paraffin, tetrahydronaphthalene, alkylated extracts or derivatives thereof, methanol, ethanol, propanol, butanol, cyclohexanol, rings Hexanone, isophor _), a strong polar solvent (for example, dimethyl sulfite, n-methyl hydral ketone or water).

It can also be added to the formulation, such as glycerin or ethylene glycol. Antifreeze and bactericides for propylene glycol Suitable defoamers are, for example, antifoaming agents based on strontium or magnesium stearate. Suitable preservatives are, for example, dichl〇rophen. &quot; Gelling agent - an example is Satiagel®. The powder, the material to be dispersed, and the powderable product can be produced by subjecting the active material to (iv) carrier or simultaneous grinding. Granules (e.g., coated particles, impregnated particles, and homogeneous particles) can be prepared by combining the active compound with a solid carrier. 128485.doc • 37 · 200838428 Examples of solid carriers are: mineral soils such as Shiqi gum, shi ware, talc, ridge clay, attaclay, limestone, lime, chalk, red basalt, Loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetics; fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea; and plant-derived products such as flour, bark Powder, wood flour and nut shell powder, cellulose powder; and other solid carriers. In general, the formulation comprises from 1 to 95% by weight of 〇·〇, preferably from 1 to 9% by weight of active compound. In this case, the active compound is used in a purity of from 9% by weight to 100% by weight, preferably from 95% by weight to 100% by weight (according to NMR spectrum). For the purpose of seed treatment, the individual formulations may be diluted 2 to 1 fold to produce an active compound concentration of from 0.001 to 6% by weight, preferably from 1 to 4% by weight, in the ready-to-use preparation. The mixture of the present invention can be used as it is, in the form of its formulation or in the form of a solution, powder or suspension which can be directly sprayed, for example, a float or dispersion, an emulsion, a paste, a powderable Oil-producing dispersion, paste

The form, by means of spraying, atomization, powder use, depending on the intended purpose; the finest possible fraction of active compound

128485.doc condensate, paste or oily dispersion). To prepare the milk, the substance as it is or dissolved in an oil or solvent can be homogenized in water by means of a wetting agent, a tackifier, or a emulsifier. However, it is also possible to prepare concentrates consisting of active substances, wetting agents, tackifiers, powders or emulsifiers and, if appropriate, solvents or oils, which are suitable for dilution with water. The concentration of the active compound in the ready-to-use preparation can be, in a relatively wide range, from 0% to 1% by weight, preferably from 0.001% to 1% by weight. %. The active compounds can also be used successfully in ultra low volume (ULV) processes, it is possible to apply formulations containing more than 95% by weight of active compound, or even to apply active compounds without additives. The following are examples of formulations: 1. Products diluted with water for application to the leaves. The products may be applied to the seed in diluted or undiluted form for the purpose of seed treatment. A) Water-soluble concentrate (SL, LS) 10 parts by weight of the active compound are dissolved in 9 parts by weight of water or a water-soluble solvent. Alternatively, add a wetting agent or other auxiliaries. The active compound is dissolved after dilution with water to give a formulation having 1% by weight (w/w) of the active compound. B) Dispersible Concentrate (DC) 20 parts by weight of the active compound are dissolved in 7 parts by weight of cyclohexanone while 10 parts by weight of a dispersing agent (for example, polyvinyl fluorenone) are added. The dispersion was diluted with water to thereby obtain a formulation having 20% (w/w) of the active compound. C) Emulsifiable Concentrate (EC) 128485.doc -39- 200838428 15 parts by weight of the active compound are dissolved in 75 parts by weight of xylene with the addition of calcium dodecylbenzenesulfonate and ethoxylated cannabis oil (In each case, it is 5 heavy injuries). The emulsion is produced by dilution with water, whereby a formulation having 1% (w/w) of active compound is obtained. D) Emulsion (EW, EO, ES) 25 parts by weight of the active compound is dissolved in 35 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and ethoxylated castor oil (in each case) 5 parts by weight). This mixture was introduced into 30 parts by weight of water by means of an emulsifier (e.g., Ultraturrax) and made into a homogeneous emulsion. Dilution with water to produce an emulsion was obtained to obtain a formulation having 25% (w/w) of active compound. E) Suspensions (SC, OD, FS) In a disturbed ball mill, 20 parts by weight of the active compound are ground together with 1 part by weight of dispersant, wetting agent and 7 parts by weight of water or organic solvent. To produce a fine suspension of the active compound. Dilution with water produces a stable suspension of the active compound, whereby a formulation having 2% by weight (w/w) of the active compound is obtained. F) Water-dispersible granules and water-soluble granules (WG, SG) 50 parts by weight of the active compound are finely ground together with the added 5 parts by weight of dispersant and wetting agent and by means of technical equipment (for example, an extruder, The spray tower, fluidized bed) is made of water-dispersible or water-soluble particles. Dilution with water produces a stable dispersion or solution of the active compound, whereby a formulation having 50% (w/w) of active compound is obtained. G) Water-dispersible powders and water-soluble powders (WP, SP, SS, WS) 75 parts by weight of active compound in a rotor-stator grinder and 25 parts of a dispersant added with 128485.doc -40-200838428 , humectant and silicone rubber are ground together. Dilution with water produces a stable dispersion or solution of the active compound, whereby a formulation having 75% (w/w) active compound is obtained. H) Gel formulation (gf) In an actuated ball mill, 20 parts by weight of active compound plus 10 parts by weight of dispersant, 1 part by weight of gelling agent wetting agent and 70 parts by weight of water or organic The solvent is ground together to produce a fine suspension of the active compound. Dilution with water yields a stable suspension of the active compound, whereby a formulation with 20% (w/w) active compound is obtained. 2. A product that is applied without application to the application of the leaves. For seed treatment purposes, the products can be applied to the seed in diluted or undiluted form. I) Powderable powder (DP, DS) 5 parts by weight of the active compound are finely ground and intimately mixed with 95 parts by weight of fine powdery chitin. This produces a pulverizable product having 5% (w/w) active compound. J) Particles (GR, FG, GG, MG) 5 parts by weight of the active compound are finely ground and combined with 95.5% by weight of the carrier, whereby an active compound having 〇·5% (w/w) is obtained. Formulations. Current methods are extrusion, spray drying or fluidized beds. This produces granules that are applied undiluted for leaf use. K) ULV solution (UL) 10 parts by weight of the active compound are dissolved in 90 parts by weight of an organic solvent such as xylene. This resulted in the production of 10% (w/w) active compound 128485.doc -41 - 200838428 ' applied to the leaves without dilution. Various types of oils, wetting agents, adjuvants, herbicides, fungicides, other pesticides or fungicides can be added to the active ingredient and, if appropriate, added immediately prior to use (tank mix). These agents are usually mixed with the agent of the present invention in a weight ratio of 1:10 to 10:1. • The e-form I and the one or more compounds II can be administered simultaneously (i.e., jointly or separately) or continuously. When applied separately, the order of administration generally has no effect on the outcome of the control. Compound I and one or more compounds are typically administered in a weight ratio that is sufficient to achieve the desired synergistic effect. In particular, the weight ratio of the compound to the compound is in the range of from 1000:1 to 1:200, preferably from 500:1 to 1:1. Depending on the desired effect, the application rate of the composition of the present invention is from J g/ha to 2,000, preferably from 5 to 15 (10) g/ha, especially 1 Torr, depending on the amount of application of Compound 1 + Chemical &amp; Up to 75〇g/ha. The compositions of the invention are effective both by contact and ingestion. • According to a preferred embodiment of the invention, the composition of the invention is applied via soil application. It is especially advantageous when used to resist ants, termites, mites or mites. • In accordance with another preferred embodiment of the present invention, the composition of the present invention is prepared as a temptation for use against non-crop pests such as ants, white stalks, wasps, flies, mosquitoes, mites, mites or mites. _preparation. The lustre may be a liquid, solid or semi-solid preparation (eg, a gel). In addition to the active ingredients listed above, the compositions of the present invention may further comprise other active ingredients. For example, fungicides, herbicides, fertilizers (128485.doc -42- 200838428 such as ammonium nitrate, urea, potash and perphosphate), plant toxins and plant growth extractants and safeners. These additional ingredients may be used in sequence, or in combination with the above-mentioned group of mouthpieces, if appropriate, or just in front of the application (tank mix). For example, the plants can be sprayed with the compositions of the invention before or after treatment with other active ingredients. The compositions of the present invention can be applied to any and all stages of development, such as prints, larvae, worms and adults. #由使的虫虫,其食品源,楼

The pest, the breeding ground or its location is contacted with a pesticidally effective amount of a mixture of the invention or a composition comprising the mixture to control the pest. "Location" means a plant, seed, soil, area, material or environment in which a pest grows or may grow. In the case of a meal, an effective amount of a pesticide means a mixture of the invention required to achieve an observable effect on growth or The amount of the composition comprising the mixture, including necrosis, death, delay, prevention and removal, disruption or otherwise reducing the appearance and activity of the target organism. The effective amount of the pesticide can vary for the various mixtures/compositions used in the present invention. The pesticide effective amount of the mixture/composition is also varied depending on the main conditions, such as the desired pesticide effect and duration, weather, target species, location, mode of application, and the like. The inventive composition can also be used to protect plants from attack or infestation by insects, worms or nematodes, which involve contact with plants or plant domains. The initially grown soil or water, or plant. In the context of the present invention, the term "plant" refers to a part of a plant or a propagation material of a plant, that is, a seed or a seedling. 128485.doc -43- 200838428 Plants which can be treated with the mixture of the invention include all genetically modified or transgenic plants, for example, due to breeding including genetic engineering methods, herbicides or eucalyptus or insecticide crops, Or plants having improved body and good characteristics compared to existing plants, which can be produced, for example, by conventional breeding methods and/or by generating mutants or by recombinant procedures. - The composition of the invention has a systemic effect and can therefore be used for protection: the young teeth are protected from leaf pests and used to treat seeds and roots

Inflicted by bandit pests. ^ Thus the composition of the present invention is suitable for treating seeds to protect the seeds from insects, insects, especially native insect pests, and to protect the roots of the resulting plants from soil and insects. Protect the roots and young teeth of the resulting plants #乂佳. More preferably, the buds of the resulting plants are protected from attack by sucking insects, wherein it is best protected from aphids. In this way, the present invention comprises a method for protecting seeds from insects, especially soils, and protecting the roots and shoots of seedlings from insects, especially soil and leaf insects. The method comprises pre-planting and/or germination. After treatment, the seed is contacted with the composition of the present invention. In particular, it is preferred that the roots and shoots of the plants are protected by the method, and that the buds of the plants are protected from the sucking type of Kunjia, and the buds of the plants are protected from the insects and insects. method. The term seed covers all types of seeds and plant propagules, including but not limited to seed seeds, seed pieces, root strips, bulbs, bulbs, fruits, tubers, grains, cuttings, cutting strips and An analog thereof, and in a preferred embodiment, means a seed. 128485.doc -44- 200838428 All suitable seeds are known for seed pulverization, seed soaking and seed granules. The term seed treatment encompasses the state of the art techniques, such as seed dressing, seed coating, and sizing.

This month also contains active compounds and cloth or seeds containing active compounds I and II. The term &quot;coated and/or contained&quot; generally means that the coating is mostly on the surface of the reproductive product, although depending on the coating method, the components may penetrate into the propagation product. When (re)planting the reproductive product, it can absorb the active ingredient. The seed of I I is a seed of a genus, a root crop, an oil crop, a vegetable, a spice, a plant, such as a seed of the following: durum wheat And ', he, wheat, barley, oats, rye, corn (feed corn and sugar jade sweet and feed corn), soybeans, oil crops, cruciferous plants, cotton to sundial, banana, rice, rape, Turnip rapeseed, beet, feed = vegetable, herb, potato, grass, lawn, turf, forage grass, idiot, leeks, pumpkin (pmnpkin/squash), kale, cabbage, pepper, steamed melon, melon, scallions Brassica species, soybeans, alfalfa: masters, onions, carrots, tuber plants such as potatoes, sorghum, tobacco, grapes, petunias, geranium / geranium, pansy and balsam Furthermore, the compositions of the present invention can also be used to treat seeds from plants that are resistant to herbicides or killing agents or insecticides by breeding including genetic engineering methods. For example, a, the active composition can be used to treat resistant Seeds of plants subjected to herbicides selected from the group consisting of: 醯 醯 urea, imiline, grass 128485.doc -45- 200838428 ammonium phosphine (glufosinate-ammonium) or glyphosate isopropyl ammonium (glyphosate - isopropylammonium) and similar active substances (see, for example, 卩-八-0242236, EP-A-242246) (WO 92/00377) (ΕΡ-Α·0257993, US Patent No. 5,013,659) or for transgenic crop plants (eg A cotton (EP-A-0142924, EP-A-0193259) capable of producing a plant resistant to certain pests of Bacillus thuringiensis toxin (Bt toxin). Furthermore, the composition of the present invention can also be used for treatment. From seeds of plants having improved characteristics compared to existing plants, which can be produced, for example, by conventional breeding methods and/or by the production of mutants or by recombinant procedures. For example, to achieve synthesis in improved plants A number of examples of recombinantly improved crop plants have been described for the purpose of starch (e.g., WO 92/11376, WO 92/14827, WO 91/19806) or transgenic crop plants with improved fatty acid composition (WO 91/13972). Seed treatment applications are carried out by spraying or dusting the seed prior to plant sowing and prior to germination of the plant seed. In seed treatment, the corresponding formulation is applied by treating the seed with an effective amount of the composition of the invention. Herein, the application rate of active compounds I and II (total amount of I+II) is generally from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, especially per 100 kg of seed. 1 g to 2. 5 kg. For specific crops such as lettuce, the application rate can be higher. Compositions particularly suitable for seed treatment can be formulated as (for example) · A soluble concentrate (SL, LS) D emulsion (EW, EO, ES) 128485.doc -46- 200838428 E suspension (SC, OD, FS) F water-dispersible granules and water-soluble granules (WG, SG) G water-dispersible powder and water-soluble powder (WP, SP, H gel formulation (GF) 1 pulverizable powder (DP, DS) Seed treatment formulations include, for example, flowable concentrate FS, solution LS, powder DS for drying treatment, water dispersible powder WS for slurry treatment, water soluble powder SS and emulsion ES and £(: and Gel formulation GF. These formulations may be applied to the seed in diluted or undiluted form. Application to the seed may be carried out directly on the seed prior to sowing, or after germination of the latter. For example, FS formulations are used for seed treatment. Typically the 'FS formulation can contain 1-800 g/Ι active ingredient, 1-200 g/Ι surfactant, 0 to 200 g/Ι antifreeze, 0 to 400 g / Ι adhesive, 〇 to 2 〇〇 g / 1 pigment and up to 1 liter of solvent, preferably water. Preferred FS formulations of the seed treated compositions of the invention typically comprise from 1 to 80% by weight (1 to 800 g/inch) of active ingredient, from 0.1 to 20% by weight (1 to 200 g/inch) of at least one of a surfactant, for example, 5 to 5% by weight of a wetting agent and 0.5 to 15% by weight of a dispersing agent, up to 20% by weight (for example, 5 to 20% by weight) of an antifreezing agent, 〇 to 15 parts by weight % (for example, 1 to 15% by weight) of pigment and/or dye, 〇 to 40% by weight (for example, 1 to 40% by weight) of binder (adhesive/adhesive), optionally up to 5% by weight (for example) , 0.1 to 5% by weight of a thickener, optionally 0.1 to 2% by weight of an antifoaming agent and, as the case may be, for example, 0. 01 to 1% by weight of a preservative (such as a biocide, antioxidant 128485. Doc-47-200838428 agent or its analog) and up to 100% by weight of filler/vehicle. In addition, the seed treatment formulation may also contain a binder and optionally a colorant. A binder may be added to improve after treatment. The active substance is on the seed. Suitable binder is block copolymer EO/po surfactant, 1 polyvinyl alcohol Polyethylene (4), polyacrylic acid sl, polymethyl acrylate vinegar, polybutene, polyisobutylene, polystyrene 1 vinylamine, polyvinylamine, polyethyleneimine (Lupasol®, Polymin®), Polyether, polyurethane vinegar, polyvinyl acetate vinegar, methyl cellulose and copolymers derived therefrom, etc. Depending on the formulation, the coloring agent may also be included in the formulation. Suitable coloring for seed treatment formulations The agent or dye is rhodamine called can-oil b), c丄 pigment red in, c丄 solvent ή, pigment blue 15:4, pigment blue i5 3, pigment blue Μ, pigment blue 15:1, pigment blue 8〇 , pigment xanthine, pigment yellow ^, pigment red 112, pigment red 48: 2, pigment red 48: 1, pigment red 57: 1, pigment red 53: 1, pigment orange 43, pigment orange 34, pigment orange 5, pigment Green%, Pigment Green 7, Pigment White 6, Yan's Material Brown 25, Testability (IV), Verification Purple 49, Acid Red Dragonfly "Red 52, Acid Red 14, Acid Blue 9, Acid Yellow 23, Alkaline Red 10 Verification red 108. The invention is also directed to seeds comprising the compositions of the invention. The amount of the compound WI or its agriculturally suitable salt will generally vary from 1 to 5 kg per 100 kg of seed per gram of seed 〇igg, especially from 1 g to 1000 g per (10) kg of seed. ^月的口口物 via contact (via soil, glass, wall, mosquito 128485.doc -48-200838428 ::: carpet, plant part or animal part) and ingestion (trigger or plant and via feeding and transfer) The preferred method of application is to enter the body of water, through the soil, cracks and fissures, = side: piles, drains, into the water, on the floor, on the wall or by the application of the surrounding bait and bait. - a preferred embodiment, the mixture of the invention is prepared as a bait preparation for achieving resistance to non-crop pests such as ants, ants, wasps, cans, mosquitoes, pterosides, beetles or cockroaches. The bait may be a liquid, A solid or semi-solid preparation (for example, a gel). The combination used in combination = is a product that is sufficiently attractive to promote consumption such as ants, white sacrifice: wasp 'soil', mosquitoes, chrysalis, etc. or cockroaches. This reference = may be selected from the sensible pheromones and/or sex pheromones readily known in the art. The mixture of the invention and its individual compositions control the transmission of diseases caused by ticks (eg , dysentery, dengue and yellow The method of fever, lymphoid moth disease: Leishman's disease deis-)) also includes treatment of sheds and living surfaces, air spray and dipping curtains, tents, clothing, mosquito nets, rope catchers or the like. The insecticidal composition for application to fibers, fabrics, knits, non-woven fabrics, woven materials or tarpaulins preferably comprises a combination comprising a composition of the invention, an ex situ repellent and at least one binder. The δ of the Moon Group can be used to protect wooden materials such as trees, wooden barriers, sleepers, etc., as well as buildings such as houses, outbuildings, and workers, as well as furniture, leather, fiber, vinyl, and wire. And cables 128485.doc -49- 200838428 to prevent ants and/or termites from infusing, and to control the damage of ants and termites to crops or humans (for example, when pests invade houses and public facilities). In the case of application to the pest habitat or nest I, the amount of active compound 1 + 11 is in the range of from 1 to 5 g, preferably from 0.001 to 20 g per 100 m2. Material protection The usual application rate is (❹) 0.01 g to 1000 g of the active compound ϊ+π per square meter of treatment material, ideally 50 g per square meter. The insecticidal composition used in material impregnation usually contains 〇〇〇1 Up to 95% by weight, preferably from 0.1 to 45% by weight, and more preferably from 1 to 25% by weight, of at least one repellent and/or insecticide. For use in a bait composition, the active compound Ι+π Typical content is from 0.0001% by weight to 15% by weight, desirably from 1% by weight to 5% by weight of active compound. The composition used may also contain other additives, such as solvents, flavoring agents, antiseptic of active materials. Agent, dye or bitter. It can also be enhanced by a specific color, shape or texture. For use in a spray composition, the S of the active ingredient Ι+π is from 0.001 to 80% by weight, preferably from 0 01 to 5% by weight, and most preferably from 1 to 15% by weight. . For use in treating crop plants, the application rate of the mixture of active ingredients of the invention may be from 1 § to 4 〇〇〇g per hectare, desirably from 25 g to 600 g per hectare, more desirably per hectare § to Within the range of 5〇〇g. [Embodiment] 128485.doc -50- 200838428 Biological synergism may be referred to as the interaction of two or more compounds in combination with the sum of the individual effects of each compound. Limpel type can be used (Limpel, LE 'Schuldt, PH ^ Lament, D. Proc. NE Weed Control· Conf· 1962, 16, 48-53, see also Colby, S. R., 1967, Calculating Synergistic and Antagonistic Responses in Herbicide Combinations, Weeds, 15, 20-22) to calculate the presence of synergism between the two mixed partners (X and Y) (controlled in %): Ε=Χ+Υ-Χ·Υ/100 Ε mixture The expected % mortality X is the % of the compound when the independent measurement is measured. Υ The % mortality of the compound in the independent measurement. If the % observed mixture is greater than the % expected mortality, the synergy is significant. The following tests demonstrate the efficacy of the compounds, mixtures or compositions of the invention in controlling pests. However, pest control protection provided by a compound, mixture or composition is not limited to such species. In some instances, it has been discovered that the combination of a compound of the invention with other invertebrate pest control compounds or agents exhibits synergistic effects against certain important invertebrate pests. The Limpel formula is used to determine the analysis of synergism or antagonism between the mixtures or compositions. Test B.1 To assess the control of vetch aphid (Megoura viciae) via contact or systemic approach. The test unit consists of a 24-well microtiter plate containing stupid bean leaves 128485.doc -51- 200838428. . The compound or mixture is formulated using a solution containing 75% water and 25% dimethyl hydrazine (DMSO). Different concentrations of the formulated compound or mixture were sprayed onto the leaf discs at 2.5 μΐ using a custom micro-atomizer and repeated twice. For the experimental mixtures in these tests, the same amount of the two mixed conjugates were separately mixed together at the desired concentration. After application, the leaf discs were air dried and 5 to 8 adult aphids were placed on the leaf discs inside the microtiter wells. The mites were then allowed to suck on the treated leaf pans and incubated for 5 days at 23 ± 1 ° C, 50 ± 5% RH (room humidity). Visual assessment of aphid mortality and fertility. The results are presented in Table 1 below: Table 1: Active compounds against the broad bean scorpion scorpion I ppm Compound II ppm Average control [%] 乙醯普0 达蜗灵 0 0 0 20 0 2 20 100 2 0 0 0 布芬净0 0 0 200 0 2 200 100 2 0 0 乙醯普0 thiamethoxam 0 0 0 0.6 0 20 0.6 100 20 0 0

Test B.2 To assess the control of boll weevil (Anthonomus grandis), the test unit consisted of a 24-well microtiter plate containing an insect diet and 20-30 eggs of the cotton aphid. 128485.doc -52- 200838428 Formulate a compound or mixture using a solution containing 75% water and 25% DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 20 μL using a custom micro-atomizer and repeated twice. For the experimental mixtures in these tests, the same amount of the two mixed conjugates were separately mixed together at the desired concentration. After application, the microtiter plate was incubated for 5 days at 23 ± 1 ° C, 50 ± 5% RH. Egg and larval mortality were assessed visually. The results are presented in Table 2 below:

Table 2: Resistant cotton compound worm active compound I ppm compound II ppm average [%] 乙醯普0 派灭净0 0 0 2 0 2 2 100 2 0 50 乙醯普0 哒螨灵0 0 0 6 25 2 6 100 2 0 25 醯普普0 布芬净0 0 0 6 0 0.6 6 100 0.6 0 0 Test B.3 To evaluate the control of the Mediterranean fruit fly (Ceratitis capitata), the test unit consists of insects Diet and consisting of a 96-well microtiter plate of 50-80 Mediterranean eggs. The compound or mixture is formulated using a solution containing 75% water and 25% DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 5 μΐ using a custom micro-atomizer and repeated twice. 128485.doc -53- 200838428 For the experimental mixtures in these tests, the same amount of the two mixed conjugates were separately mixed at the desired concentration. After application, the microtiter plate was incubated for 5 days at 28 ± rc, 80 ± 5% RH. Egg and larval mortality were assessed visually. The results are presented in Table 3 below: Table 3: Activity against Mediterranean fruit fly Compound I ppm Compound II ppm Average control [%] 乙醯普0 派灭净0 0 0 2 0 2 2 100 2 0 25 乙醯普0 Fipronil 0 0 0 0.6 0 2 0.6 100 2 0 25 Test B. 4 To assess the control of tobacco budworm (Heliothis virescens), the test unit consisted of an insect-containing diet and 15-25 tobacco budworms The 96-well microtiter plate of eggs is composed. The compound or mixture is formulated using a solution containing 75% water and 25% DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 10 μΐ using a custom micro-atomizer and repeated twice. For the experimental mixtures in these tests, the same amount of the two mixed conjugates were separately mixed together at the desired concentration. After application, the microtiter plate was incubated for 5 days at 28 ± 1 ° C and 80 ± 5% RH. Egg and larval mortality were assessed visually. The results are presented in Table 4 below: 128485.doc -54- 200838428 Table 4: Activity against Igmoga sinensis Compound I ppm Compound II ppm Average control [%] 0 0 0 醯 醯 普 0 哒 哒 0.2 0.2 0 200 0 , 2 75 200 0 0 Test B.5 In order to evaluate the control of green peach aphid (Myzus persica) φ system with a mixed age of wingless peach aphid infected with two true leaves of the bell pepper seedlings (buds The ends are removed) (about 3〇_60 aphids per seedling). After one day of infestation, count the live insects on each seedling (count before treatment) and then 1:1 acetone: water (+〇 · 〇 1% by volume of the technical compound)

Leaching in KineticTM) dilution. The treated seedlings can be maintained at 28 after being air dried. 〇 Constant fluorescent lighting. After 5 days of treatment, the live aphids on each seedling were counted (count after treatment) and then the % mortality was estimated from the pre-treatment count. Calculate the average. Mortality, each place • Repeat 3 to 9 times (1 repetition = 1 seedling). There was no aphid mortality in the diluted control. In the test 5·5, the Limpel formula was used to determine if the insecticidal mixture had a synergistic effect. If the mixture is. If the observed mortality rate is greater than the % expected death rate, the synergy is significant. Table 5. Independent Activity of Industrial Grade Insecticides (Ethylpyrrolidamine, Idamine and Fipronil) Resistant to Lamp Rejuvenation Seedlings on Peach Series 128485.doc -55- 200838428 乙醯普3 达达胺〇· 〇!ΈοΓ Fluoride guess 0.6 dose concentration (εεεξ!

Bell Pepper Table 6 · Ethylpyrrolidone (all industrial grade) mixture to resist the synergistic effect of the peach aphid on the seedlings Pesticide mixture % observed mortality - ^86-- 醯 醯 (3 ppm) + EDTA (0.04 ppm) acetaminophen (3 ppm) + idalide (0.01 ppm) 80 acetaminophen (1 ppm) + idalide (0.04 ppm) ^^83 acetaminophen (1 ppm) + benefit Damine (0.01 ppm) 16 Based on Limpel's formula, % observed mortality is greater than % expected mortality, which has a synergistic effect. Table 7.·················································· Acetyl (3 ppm) + gas disk nitrile (0.6 ppm) Acetyl (2 ppm) + fipronil (1 ppm) Acetyl (2 ppm) + fipronil (0.6 ppm) % Observed mortality 92 92

Based on the Limpel style. /〇 Observed mortality is greater than expected mortality, which has a synergistic effect. This table 128485.doc -56-

Claims (1)

200838428 X. Patent application scope: 1 · A pesticide composition comprising i) at least one 3-ethylindol-1-phenylpyrazole compound of formula I Ο Wherein X is N or C-R5; ... is a heart--alkyl or CVC4 haloalkyl; R2 is NR6R7 or S(0)nR8; r3 is halogen, C!-C4 haloalkyl, CVC* haloalkoxy , SF5 or S(〇)pR9; R is hydrogen or _; R5 is γ; R is hydrogen, CrC* alkyl, Ci_C4 haloalkyl, C(0)R10, S(〇)qCF3; R7 is hydrogen Or a Cl-C4 alkyl group, or "joined with a reverse 7 to form a c4-c6 alkylene group, wherein one CH2 group can be replaced by oxygen or N-R&quot;; rn R, RG, RU are each independent The ground is hydrogen, CVC4 alkyl or Li_C4 haloalkyl; m, n, P and q are each independently 〇, 】 or 2; 128485, doc 200838428 or a salt thereof, and (ii) one or more selected from the following A group of compounds Π ·· A.1 is selected from the following GABA-gated gas channel antagonists Ala N-ethyl-2,2-dimethylpropanamide-2-(2,6· Dichloro-α·α·α-tris-p-tolyl)anthracene, Ν-ethyl·2,2-dichloro-1-indolylcyclopropane-carbenamide_2-(2,6-dichloro _α·α·α-trifluoro-p-tolyl) oxime; Alb consists of ethiprole, fipronil, pyrafluprole, pyripolle, vaniliprole and phenyl pi-salt compound Π.Α2·1 Category of phenylpyrazole: 2.2 nicotinic acetylcholine receptor agonist/antagonist selected from the group consisting of nicotin, thiocyclam, acetamiprid, chlorosigma ( Chlothianidin), dinotefuran, imidacloprid, nitenpyram, thiacloprid, 11 thiamethoxam and AKD-1022 Category; and ectopic nicotinic acetylcholine receptor agonist spinosyn 128485.doc 200838428 A.3 A.4 A.5 A.6 A.7 into A.8 A.9 A.10 (spinosad); a juvenile hormone selected from the group consisting of: hydroprene, kinoprene, fenoxycarb, and pyriproxyfen; Oxidative phosphorylation compounds of various substances: diafenthiuron, fenbutatin oxide, propargite, and chlorfenapyr; chitin biosynthesis selected from the following Inhibitors: buprofezin and bistrifluron, diflubenzuron, flufen a class of benzyl urea consisting of noxuron), hexaflumuron, lufenuron, and novaluron; a molting agent selected from the group consisting of cyromazine and a class of ecdysone agonists composed of methoxyfenozide and tebufenozide; a mitochondrial electron transport inhibitor selected from the group consisting of pyridaben and oxalidamide 1: 〇1£6叩71^(!) and flufenerim; a voltage-dependent sodium channel blocker selected from indoxacarb and metaflumizone; Inhibitors of lipid synthesis: spirodiclofen, spiromesifen and spirotetramat; a group of compounds consisting of the following compounds: guanamine fluoromethame 128485.doc 200838428 ( Amidoflumet), amitraz, bifenazate, clofentezine, cyenopyrafen, cyflumetofen, etoxazole, benzene Flubendiamide, flupyrazophos, sold -One (hexythiazox), to send off the net (pymetrozine), insect propyl starch ether (pyridalyl) and trip-fluoro what month were (pyrifluquinazon), as an active ingredient. 2. The composition of claim 1, wherein the substituent of the compound of formula (I) has the following meaning: X is N or C-R5; m is 0 or 1; R1 is fluorenyl; R2 is NR6R7; R3 is halogen Or 匕-匕-dentyl; R4 is halogen; R5 is halogen; R6 is hydrogen, C!-C2 alkyl, CVC2 i alkyl, C(0)CH3, s(o)2cf3; R7 is hydrogen or CVC2 alkane Or the group NR6R7 is 4-morpholinyl, 1-oxaridinyl, 1-piperidinyl, 1-bromomethyl or 4-methylpyrylene. 3. The composition of claim 1, wherein the substituents of the compound of formula (I) have the following meanings: 128485.doc 200838428 X is C-R5; m is 0 or 1; R1 is fluorenyl; R2 is NH2 And R3 is a self-primary or (^-(:2 fluoroalkyl; R4 is a self-priming; and R5 is a self-priming. 4. The composition of claim 1, wherein the substituent of the compound of the formula (I) has The following meanings: 1 X is C-R5; m is 1; R1 is a fluorenyl group; R2 is NH2; R3 is a trifluoromethyl group; R4 is chlorine; and R5 is chlorine. 5 · As detailed in any of the claims The composition, wherein the at least one compound II is selected from the group consisting of: in the group A.1, selected from the group consisting of N-ethyl·2,2-dimethylpropanamide-2-(2,6-dichloro- α·α·α-trifluoro-p-tolyl)fluorene, N-ethyl-2,2-dichloro-1-mercaptocyclopropanone, and methotrexate-2-(2,6-digas-α · α·α-trifluoro-p-phenylene) oxime, acetamiprid, fipronil, piperacop, piperid or van der phenyl carbazole compound ΙΙ.Α2·1 ; in Α·2 In the group, it is selected from the group consisting of insecticidal ring, acetamiprid, chlorhexidine, and furosel 128485.doc - 5 - 200838428 Amine, edamine, imidacloprid, thiacloprid , thiamethoxam, AKD_1〇22 and spinosyn; in group A.4, selected from fenfenyl; in group A.5, selected from bufphenine; in group Α7, selected Self-purifying and flufenaline; in the Α·8 group, selected from indoxacarb and cyanofluorfen; in the Α·9 group, selected from snail ester, spironolactone and spirotetrazol In the group of Α·10, selected from the group consisting of triterpenoids, flufendipine, chlorfenapyr, acetamiprid, and uranyl fluoride. 6. The composition of any one of items 1 to 5 Wherein the compound η is selected from the group consisting of: Ν_ethyl-2,2-dimercaptopropionamide_2-(2,6-dichloro-αα α-trifluoro-p-tolyl) oxime and ruthenium- A1 group consisting of ethyl 2,2_di-nitro-1-methylcyclopropane-carbenamide 2 (2,6-dichloro-α·α·α-trifluoro-p-tolyl) oxime. The composition of any one of claims 1 to 5, wherein the compound η is selected from the group consisting of fluocinonitrile and acetaminophen. 8 · The combination of any one of items 1 to 5 And a compound selected from the group A to 2, which is a composition of any one of claims 1 to 5, wherein the compound II is a compound of the group A to 2, The compound of any one of claims 1 to 5, wherein the compound II selected from the group consisting of Α·5 is buffing. The composition of any one of claims 1 to 5, wherein the compound II selected from the group consisting of α·7 is olfactory or flufen. The composition of any one of claims 1 to 5, wherein the compound II selected from the group consisting of α·8 is fluorene. The composition according to any one of claims 1 to 5, wherein the compound II selected from the group consisting of α·9 is spirodecyl ester or spirotetramat. The composition of any one of claims 1 to 5, wherein the compound II selected from the group consisting of Α·10 is fenacetin or piperazine. The composition of claim 1 to 2, which comprises the compound of the formula 1 and one or more compounds II in a weight ratio of 丨10 to (8. 16. Use of a composition according to any one of claims 1 to 15 for combating insects, arachnids or nematodes. 17. A method of protecting a plant from infestation or infestation by an insect, a worm, or a nematode, which comprises causing the plant or the soil or water in which the plant is grown to be effective as a pesticide, as in any one of claims 1 to 15. The composition is in contact. 1 8 · A method for controlling insects, arachnids or nematodes, comprising an insect, aphid or nematode or its food source, habitat, breeding ground or violent location and pesticidal effective amount as claimed in claim 1 The composition of any of 15 is contacted. The method of claim 17 or 18, wherein the composition of any one of claims 1 to 2 is administered in an amount of from 5 g/ha to 2000 g/ha. 20. A method of protecting a seed comprising contacting the seed with a pesticidally effective amount of a composition according to any one of claims 1 to 15. The method of claim 20, wherein the composition of any one of claim 15 is administered in an amount of from 〇jg to 1〇kg per 100 kg of seed. A seed comprising the composition of any one of claims 1 to 28, 128485.doc -7- 200838428, a compound I+II having a parental content of 100 kg of seed 〇·1 § to 1 〇 kg. 23. The method of any one of claims 17 to 21, wherein the compound of the formula I and the lanthanide of the formula I as defined in any one of claims 1 to 15 are administered simultaneously, ie, in combination or separately, or continuously Apply. 24. A pesticide or parasiticidal formulation comprising a liquid or solid carrier and a composition according to any one of claims 1 to 15. 128485.doc 200838428 VII. Designated representative map: (1) The representative representative of the case is: (none) (2) The symbolic symbol of the representative figure is simple: • 8. If there is a chemical formula in this case, please reveal the characteristics that can best show the invention. Chemical formula·· 〇 128485.doc