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TW200745126A - Bicyclic heteroaryl derivatives as cannabinoid receptor modulators - Google Patents

Bicyclic heteroaryl derivatives as cannabinoid receptor modulators

Info

Publication number
TW200745126A
TW200745126A TW096106748A TW96106748A TW200745126A TW 200745126 A TW200745126 A TW 200745126A TW 096106748 A TW096106748 A TW 096106748A TW 96106748 A TW96106748 A TW 96106748A TW 200745126 A TW200745126 A TW 200745126A
Authority
TW
Taiwan
Prior art keywords
cannabinoid
cannabinoid receptor
receptor modulators
disorders
bicyclic heteroaryl
Prior art date
Application number
TW096106748A
Other languages
Chinese (zh)
Inventor
Mrinalkanti Kundu
Neelima Khairatkar-Joshi
Suhas Mangesh Nadkarni
Rameshwar Madhavrao Pansare
Pallavi Karnik
Original Assignee
Glenmark Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa
Publication of TW200745126A publication Critical patent/TW200745126A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The present invention relates to novel bicyclic derivatives as cannabinoid receptor modulators, in particular cannabinoid 1 (CB1) or cannabinoid 2 (CB2) receptor modulators, and uses thereof for treating diseases, conditions and/or disorders modulated by a cannabinoid receptor (such as pain, neurodegenative disorders, eating disorders, weight loss or control, obesity, smoking cessation, alcohol dependency, depression, and attention deficit hyperactivity disorder). Pharmaceutical compositions containing the described compounds, which can be used for the treatment of diseases, condition and/or disorders mediated by a cannabinoid receptor (such as CB1 or CB2) are further provided.
TW096106748A 2006-02-27 2007-02-27 Bicyclic heteroaryl derivatives as cannabinoid receptor modulators TW200745126A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN275MU2006 2006-02-27
US78105506P 2006-03-10 2006-03-10
IN1146MU2006 2006-07-18
US82147506P 2006-08-04 2006-08-04
IN2088MU2006 2006-12-20

Publications (1)

Publication Number Publication Date
TW200745126A true TW200745126A (en) 2007-12-16

Family

ID=38437745

Family Applications (1)

Application Number Title Priority Date Filing Date
TW096106748A TW200745126A (en) 2006-02-27 2007-02-27 Bicyclic heteroaryl derivatives as cannabinoid receptor modulators

Country Status (4)

Country Link
AR (1) AR059643A1 (en)
PE (1) PE20080114A1 (en)
TW (1) TW200745126A (en)
WO (1) WO2007096764A2 (en)

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Also Published As

Publication number Publication date
WO2007096764A3 (en) 2008-07-10
PE20080114A1 (en) 2008-04-16
WO2007096764A2 (en) 2007-08-30
AR059643A1 (en) 2008-04-16

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