TW200744613A - Compositions for reducing the incidence of drug induced arrhythmia - Google Patents
Compositions for reducing the incidence of drug induced arrhythmiaInfo
- Publication number
- TW200744613A TW200744613A TW095126806A TW95126806A TW200744613A TW 200744613 A TW200744613 A TW 200744613A TW 095126806 A TW095126806 A TW 095126806A TW 95126806 A TW95126806 A TW 95126806A TW 200744613 A TW200744613 A TW 200744613A
- Authority
- TW
- Taiwan
- Prior art keywords
- compositions
- incidence
- methods
- reducing
- drug
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 206010003119 arrhythmia Diseases 0.000 title abstract 2
- 230000006793 arrhythmia Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 2
- MREBEPTUUMTTIA-PCLIKHOPSA-N Azimilide Chemical compound C1CN(C)CCN1CCCCN1C(=O)N(\N=C\C=2OC(=CC=2)C=2C=CC(Cl)=CC=2)CC1=O MREBEPTUUMTTIA-PCLIKHOPSA-N 0.000 abstract 2
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 2
- 208000018452 Torsade de pointes Diseases 0.000 abstract 2
- 208000002363 Torsades de Pointes Diseases 0.000 abstract 2
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 2
- 229950001786 azimilide Drugs 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000000164 antipsychotic agent Substances 0.000 abstract 1
- 229940005529 antipsychotics Drugs 0.000 abstract 1
- 229940082627 class iii antiarrhythmics Drugs 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 229940030606 diuretics Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70155505P | 2005-07-22 | 2005-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200744613A true TW200744613A (en) | 2007-12-16 |
Family
ID=37547445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095126806A TW200744613A (en) | 2005-07-22 | 2006-07-21 | Compositions for reducing the incidence of drug induced arrhythmia |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8183284B2 (zh) |
| EP (1) | EP1906966A2 (zh) |
| JP (1) | JP4880685B2 (zh) |
| KR (1) | KR20080017489A (zh) |
| CN (1) | CN101227908A (zh) |
| AR (1) | AR055091A1 (zh) |
| AU (1) | AU2006271230A1 (zh) |
| BR (1) | BRPI0613670A2 (zh) |
| CA (1) | CA2615975C (zh) |
| IL (1) | IL188831A0 (zh) |
| MA (1) | MA29622B1 (zh) |
| MX (1) | MX2008001063A (zh) |
| NO (1) | NO20080890L (zh) |
| PE (1) | PE20070369A1 (zh) |
| RU (1) | RU2376994C2 (zh) |
| SM (1) | SMP200800012B (zh) |
| TW (1) | TW200744613A (zh) |
| WO (1) | WO2007010498A2 (zh) |
| ZA (1) | ZA200800564B (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105534976A (zh) * | 2016-01-14 | 2016-05-04 | 山东大学 | 2-(2,2-二苯基环丙基)-4,5-二氢-1h-咪唑在制备抗神经退化性疾病药物中的应用 |
| CN110022908B (zh) * | 2016-05-19 | 2022-04-05 | 塔布拉拉莎医疗保健公司 | 具有降低的药物相关毒性的治疗方法和鉴定由处方药物引起的患者伤害的可能性的方法 |
| EP3569249A4 (en) * | 2016-12-27 | 2020-11-11 | Osaka University | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF REFRACTORY HEART DISEASE |
| KR20210072013A (ko) * | 2018-11-02 | 2021-06-16 | (주)셀트리온 | 비후성 심근증 치료용 약학 조성물 |
| CA3145041A1 (en) * | 2019-07-29 | 2021-02-04 | Matthias Rath | Ascorbate in the prevention of statin induced vascular calcification |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB742544A (en) | 1952-02-23 | 1955-12-30 | Kodak Ltd | Enteric products |
| FR2833M (zh) | 1962-06-12 | 1964-10-05 | I N I C O Ind Nuclear Invest C | |
| GB1142757A (en) | 1967-01-26 | 1969-02-12 | Carter Wallace | Therapeutic compositions |
| IL34145A0 (en) | 1969-03-24 | 1970-05-21 | Monsanto Co | Improved effervescent compositions |
| BE759520A (fr) * | 1969-11-28 | 1971-04-30 | Aspro Nicholas Ltd | Compositions d'aspirine |
| US3887700A (en) * | 1969-11-28 | 1975-06-03 | Aspro Nicholas Ltd | Analgesic formulations |
| JPS58126879A (ja) | 1982-01-25 | 1983-07-28 | Nippon Chemiphar Co Ltd | 光学活性なピペラジン誘導体ならびに心筋梗塞の予防および治療剤 |
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| WO1990009185A1 (en) | 1989-02-16 | 1990-08-23 | Angio-Medical Corp. | Composition and method for treatment of gastric and duodenal ulcers and mucosal erosions |
| GB9104854D0 (en) | 1991-03-07 | 1991-04-17 | Reckitt & Colmann Prod Ltd | Sustained release compositions |
| JP3228347B2 (ja) * | 1991-06-25 | 2001-11-12 | 三菱化学株式会社 | シクロプロペノン誘導体 |
| DE69321087T2 (de) * | 1992-12-25 | 1999-05-20 | Mitsubishi Chemical Corp., Tokio/Tokyo | Alpha-aminoketon Derivate |
| US6316487B1 (en) * | 1993-06-16 | 2001-11-13 | Aryx Therapeutics | Compounds for treatment of cardiac arrhythmia synthesis, and methods of use |
| AU5787996A (en) * | 1995-04-19 | 1996-11-07 | Lipoprotein Technologies, Inc. | Compositions, kits, and methods for administration of antilipemic and anti-platelet aggregation drugs |
| TWI238064B (en) * | 1995-06-20 | 2005-08-21 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| DE69734290T2 (de) * | 1996-11-05 | 2006-07-06 | The Children's Medical Center Corp., Boston | Mittel zur hemmung von angiogenese enthaltend thalodomid und einen nsaid |
| US6245797B1 (en) * | 1997-10-22 | 2001-06-12 | Merck & Co., Inc. | Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease |
| US6884792B2 (en) * | 1999-01-08 | 2005-04-26 | Marvin B. Bacaner | Bretylium compositions and kits and their use in preventing and treating cardiovascular conditions |
| CA2358459C (en) | 1999-01-08 | 2011-05-24 | Marvin B. Bacaner | Novel bretylium compositions and kits, and their use in preventing and treating cardiovascular conditions |
| FR2838057B1 (fr) * | 2002-04-05 | 2005-07-08 | Servier Lab | Nouvelle association d'un antithrombotique et d'aspirine |
| JP2005531532A (ja) | 2002-04-05 | 2005-10-20 | メルク エンド カムパニー インコーポレーテッド | アレンドロナートおよびビタミンｄ製剤を用いる骨吸収阻害法 |
| US20040137054A1 (en) * | 2002-05-03 | 2004-07-15 | Alexandra Hager | Stable pharmaceutical formulation for a combination of a statin and an ace-inhibitors |
| BR0312426A (pt) * | 2002-07-03 | 2005-12-06 | Esperion Therapeutics Inc | Composição farmacêutica, métodos para tratar, prevenir ou controlar um colesterol, dislipidemia ou distúrbio relacionado, para reduzir ou evitar um efeito adverso associado com monoterapia de pantetina e para reduzir ou evitar um efeito adverso associado com monoterapia de segundo agente ativo, e, kit |
| US20050142129A1 (en) * | 2002-10-15 | 2005-06-30 | Mangano Dennis T. | Methods of preventing morbidity and mortality by perioperative administration of a blood clotting inhibitor |
| WO2005018635A2 (en) | 2003-08-07 | 2005-03-03 | Cardiome Pharma Corp. | Ion channel modulating activity i |
| PE20050438A1 (es) * | 2003-10-20 | 2005-06-14 | Esperion Therapeutics Inc | Formulas farmaceuticas, metodos y regimenes de dosificacion para el tratamiento y la prevencion de sindromes coronarios agudos |
-
2006
- 2006-07-20 BR BRPI0613670-2A patent/BRPI0613670A2/pt not_active IP Right Cessation
- 2006-07-20 RU RU2007148908/15A patent/RU2376994C2/ru not_active IP Right Cessation
- 2006-07-20 AU AU2006271230A patent/AU2006271230A1/en not_active Abandoned
- 2006-07-20 US US11/489,756 patent/US8183284B2/en not_active Expired - Fee Related
- 2006-07-20 CA CA2615975A patent/CA2615975C/en not_active Expired - Fee Related
- 2006-07-20 CN CNA200680026609XA patent/CN101227908A/zh active Pending
- 2006-07-20 KR KR1020087001549A patent/KR20080017489A/ko not_active Abandoned
- 2006-07-20 WO PCT/IB2006/052496 patent/WO2007010498A2/en not_active Ceased
- 2006-07-20 MX MX2008001063A patent/MX2008001063A/es unknown
- 2006-07-20 EP EP06780154A patent/EP1906966A2/en not_active Withdrawn
- 2006-07-20 SM SM200800012T patent/SMP200800012B/it unknown
- 2006-07-20 JP JP2008522160A patent/JP4880685B2/ja not_active Expired - Fee Related
- 2006-07-21 TW TW095126806A patent/TW200744613A/zh unknown
- 2006-07-21 AR ARP060103156A patent/AR055091A1/es unknown
- 2006-07-21 PE PE2006000884A patent/PE20070369A1/es not_active Application Discontinuation
-
2008
- 2008-01-09 MA MA30561A patent/MA29622B1/fr unknown
- 2008-01-17 ZA ZA200800564A patent/ZA200800564B/xx unknown
- 2008-01-17 IL IL188831A patent/IL188831A0/en unknown
- 2008-02-21 NO NO20080890A patent/NO20080890L/no not_active Application Discontinuation
-
2012
- 2012-03-22 US US13/427,458 patent/US20120178724A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120178724A1 (en) | 2012-07-12 |
| WO2007010498A2 (en) | 2007-01-25 |
| CN101227908A (zh) | 2008-07-23 |
| RU2007148908A (ru) | 2009-08-27 |
| NO20080890L (no) | 2008-03-03 |
| SMAP200800012A (it) | 2008-02-27 |
| MA29622B1 (fr) | 2008-07-01 |
| BRPI0613670A2 (pt) | 2011-01-25 |
| US20070021395A1 (en) | 2007-01-25 |
| JP2009502773A (ja) | 2009-01-29 |
| JP4880685B2 (ja) | 2012-02-22 |
| AR055091A1 (es) | 2007-08-08 |
| US8183284B2 (en) | 2012-05-22 |
| AU2006271230A1 (en) | 2007-01-25 |
| ZA200800564B (en) | 2008-12-31 |
| PE20070369A1 (es) | 2007-05-16 |
| MX2008001063A (es) | 2008-03-19 |
| EP1906966A2 (en) | 2008-04-09 |
| IL188831A0 (en) | 2008-08-07 |
| RU2376994C2 (ru) | 2009-12-27 |
| CA2615975C (en) | 2012-11-27 |
| KR20080017489A (ko) | 2008-02-26 |
| CA2615975A1 (en) | 2007-01-25 |
| SMP200800012B (it) | 2008-02-27 |
| WO2007010498A3 (en) | 2007-05-31 |
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