TW200730527A - Fused heterocyclic compound - Google Patents
Fused heterocyclic compoundInfo
- Publication number
- TW200730527A TW200730527A TW095144339A TW95144339A TW200730527A TW 200730527 A TW200730527 A TW 200730527A TW 095144339 A TW095144339 A TW 095144339A TW 95144339 A TW95144339 A TW 95144339A TW 200730527 A TW200730527 A TW 200730527A
- Authority
- TW
- Taiwan
- Prior art keywords
- alkyl group
- hydrogen atom
- alkyl
- halogen atom
- heterocyclic compound
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005349858 | 2005-12-02 | ||
| JP2006060648 | 2006-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200730527A true TW200730527A (en) | 2007-08-16 |
Family
ID=37897379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095144339A TW200730527A (en) | 2005-12-02 | 2006-11-30 | Fused heterocyclic compound |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20100216788A1 (zh) |
| EP (1) | EP1957495A1 (zh) |
| JP (1) | JP2009517333A (zh) |
| KR (1) | KR20080084823A (zh) |
| AR (1) | AR057961A1 (zh) |
| AU (1) | AU2006319787A1 (zh) |
| BR (1) | BRPI0619911A2 (zh) |
| CA (1) | CA2631066A1 (zh) |
| CR (1) | CR10057A (zh) |
| MA (1) | MA30046B1 (zh) |
| NO (1) | NO20082870L (zh) |
| PE (1) | PE20071089A1 (zh) |
| RU (1) | RU2008126949A (zh) |
| TW (1) | TW200730527A (zh) |
| WO (1) | WO2007064045A1 (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2389731C2 (ru) * | 2004-06-02 | 2010-05-20 | Такеда Фармасьютикал Компани Лимитед | Конденсированное гетероциклическое соединение |
| RU2009126576A (ru) * | 2006-12-12 | 2011-01-20 | Такеда Фармасьютикал Компани Лимитед (Jp) | Конденсированное гетероциклическое соединение |
| US7825127B2 (en) | 2006-12-28 | 2010-11-02 | Takeda Pharmaceutical Company, Limited | Method for treating cancer |
| EP2163258A1 (en) | 2007-06-19 | 2010-03-17 | Takeda Pharmaceutical Company Limited | Preventive/remedy for cancer |
| TW200940546A (en) * | 2008-03-03 | 2009-10-01 | Takeda Pharmaceutical | Combination drug |
| WO2009113560A1 (ja) * | 2008-03-12 | 2009-09-17 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| AU2012273133A1 (en) | 2011-06-20 | 2013-11-07 | E. I. Du Pont De Nemours And Company | Heterocyclic compounds for treating helminth infections |
| WO2013159095A1 (en) | 2012-04-20 | 2013-10-24 | Anderson Gaweco | Ror modulators and their uses |
| RU2712220C2 (ru) * | 2013-07-31 | 2020-01-27 | Мерк Патент Гмбх | Пиридины, пиримидины и пиразины в качестве ингибиторов тирозинкиназы брутона и их применение |
| GB201520499D0 (en) * | 2015-11-20 | 2016-01-06 | Medical Res Council Technology | Compounds |
| AR119494A1 (es) * | 2019-07-29 | 2021-12-22 | Servier Lab | DERIVADOS DE 6,7-DIHIDRO-5H-PIRIDO[2,3-c]PIRIDAZIN-8-ILO, COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN Y SUS USOS COMO AGENTES PROAPOPTÓTICOS |
| EP4323356A1 (en) | 2021-04-13 | 2024-02-21 | Nuvalent, Inc. | Amino-substituted heterocycles for treating cancers with egfr mutations |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| RU2389731C2 (ru) * | 2004-06-02 | 2010-05-20 | Такеда Фармасьютикал Компани Лимитед | Конденсированное гетероциклическое соединение |
| CN101031570B (zh) * | 2004-07-30 | 2012-09-05 | 梅特希尔基因公司 | Vegf受体和hgf受体信号的抑制剂 |
| TW200740820A (en) * | 2005-07-05 | 2007-11-01 | Takeda Pharmaceuticals Co | Fused heterocyclic derivatives and use thereof |
-
2006
- 2006-11-30 TW TW095144339A patent/TW200730527A/zh unknown
- 2006-12-01 PE PE2006001541A patent/PE20071089A1/es not_active Application Discontinuation
- 2006-12-01 RU RU2008126949/04A patent/RU2008126949A/ru not_active Application Discontinuation
- 2006-12-01 EP EP06834254A patent/EP1957495A1/en not_active Withdrawn
- 2006-12-01 CA CA002631066A patent/CA2631066A1/en not_active Abandoned
- 2006-12-01 AR ARP060105330A patent/AR057961A1/es unknown
- 2006-12-01 AU AU2006319787A patent/AU2006319787A1/en not_active Abandoned
- 2006-12-01 KR KR1020087016193A patent/KR20080084823A/ko not_active Withdrawn
- 2006-12-01 BR BRPI0619911A patent/BRPI0619911A2/pt not_active IP Right Cessation
- 2006-12-01 WO PCT/JP2006/324499 patent/WO2007064045A1/en not_active Ceased
- 2006-12-01 US US12/095,543 patent/US20100216788A1/en not_active Abandoned
- 2006-12-01 JP JP2008520459A patent/JP2009517333A/ja not_active Withdrawn
-
2008
- 2008-06-09 CR CR10057A patent/CR10057A/es not_active Application Discontinuation
- 2008-06-11 MA MA31024A patent/MA30046B1/fr unknown
- 2008-06-24 NO NO20082870A patent/NO20082870L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007064045A1 (en) | 2007-06-07 |
| RU2008126949A (ru) | 2010-01-10 |
| NO20082870L (no) | 2008-09-01 |
| MA30046B1 (fr) | 2008-12-01 |
| AU2006319787A1 (en) | 2007-06-07 |
| PE20071089A1 (es) | 2007-11-19 |
| EP1957495A1 (en) | 2008-08-20 |
| JP2009517333A (ja) | 2009-04-30 |
| AR057961A1 (es) | 2007-12-26 |
| BRPI0619911A2 (pt) | 2016-08-30 |
| CR10057A (es) | 2008-07-29 |
| US20100216788A1 (en) | 2010-08-26 |
| CA2631066A1 (en) | 2007-06-07 |
| KR20080084823A (ko) | 2008-09-19 |
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