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TW200736397A - Method of protein production using anti-senescence compounds - Google Patents

Method of protein production using anti-senescence compounds

Info

Publication number
TW200736397A
TW200736397A TW095139179A TW95139179A TW200736397A TW 200736397 A TW200736397 A TW 200736397A TW 095139179 A TW095139179 A TW 095139179A TW 95139179 A TW95139179 A TW 95139179A TW 200736397 A TW200736397 A TW 200736397A
Authority
TW
Taiwan
Prior art keywords
cell culture
protein production
senescence
senescence compound
culture medium
Prior art date
Application number
TW095139179A
Other languages
English (en)
Inventor
Yen-Tung Luan
Wen-Ge Wang
Paul Thoday
Denis Drapeau
Judy Chou
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37873105&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200736397(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of TW200736397A publication Critical patent/TW200736397A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • C12N2500/33Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
TW095139179A 2005-10-24 2006-10-24 Method of protein production using anti-senescence compounds TW200736397A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72957305P 2005-10-24 2005-10-24

Publications (1)

Publication Number Publication Date
TW200736397A true TW200736397A (en) 2007-10-01

Family

ID=37873105

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095139179A TW200736397A (en) 2005-10-24 2006-10-24 Method of protein production using anti-senescence compounds

Country Status (23)

Country Link
US (1) US20070110743A1 (zh)
EP (1) EP1941026B1 (zh)
JP (2) JP2009512459A (zh)
KR (1) KR101402634B1 (zh)
CN (1) CN101297027B (zh)
AR (1) AR058140A1 (zh)
AU (1) AU2006306433B2 (zh)
BR (1) BRPI0617744A2 (zh)
CA (1) CA2627003C (zh)
CR (1) CR9897A (zh)
DK (1) DK1941026T3 (zh)
EC (1) ECSP088395A (zh)
ES (1) ES2485374T3 (zh)
IL (1) IL190550A (zh)
NI (1) NI200800111A (zh)
NO (1) NO20081622L (zh)
PE (1) PE20070796A1 (zh)
PL (1) PL1941026T3 (zh)
PT (1) PT1941026E (zh)
RU (1) RU2491347C2 (zh)
SI (1) SI1941026T1 (zh)
TW (1) TW200736397A (zh)
WO (1) WO2007050498A2 (zh)

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US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
TW200902708A (en) * 2007-04-23 2009-01-16 Wyeth Corp Methods of protein production using anti-senescence compounds
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US8895709B2 (en) 2008-10-20 2014-11-25 Abbvie Inc. Isolation and purification of antibodies using protein A affinity chromatography
US8859235B2 (en) 2009-08-14 2014-10-14 Basf Se Methods in cell cultures, and related inventions, employing certain additives
EP2601287B1 (en) 2010-08-05 2015-01-07 Amgen Inc. Dipeptides to enhance yield and viability from cell cultures
EP2611904A2 (en) * 2010-08-31 2013-07-10 Friesland Brands B.V. Culture medium for eukaryotic cells
EP2702077A2 (en) 2011-04-27 2014-03-05 AbbVie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
TW201247874A (en) * 2011-05-25 2012-12-01 United Biomedical Inc Method for producing the activity of bone activating protein
US9505833B2 (en) 2012-04-20 2016-11-29 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
SG11201504249XA (en) 2012-09-02 2015-07-30 Abbvie Inc Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
MX360649B (es) * 2013-03-13 2018-11-12 Anteis Sa Péptidos para el rejuvenecimiento de la piel y métodos de uso de los mismos.
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
EP2970875B2 (en) 2013-03-15 2025-11-26 F. Hoffmann-La Roche AG Cell culture compositions with antioxidants and methods for polypeptide production
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
MX374124B (es) 2013-10-16 2025-03-05 Outlook Therapeutics Inc Formulaciones de tampón para la estabilidad de anticuerpo mejorada.
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
CN104398398A (zh) * 2014-10-27 2015-03-11 陈少威 一种细胞量子动力素(平衡剂)及其使用方法
MA40864A (fr) * 2014-10-31 2017-09-05 Biogen Ma Inc Hypotaurine, gaba, bêta-alanine et choline pour la régulation de l'accumulation de sous-produits résiduaires dans des procédés de culture de cellules mammifères
EP3247718B1 (en) 2015-01-21 2021-09-01 Outlook Therapeutics, Inc. Modulation of charge variants in a monoclonal antibody composition
TWI870789B (zh) 2015-08-04 2025-01-21 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
WO2017083224A1 (en) 2015-11-09 2017-05-18 Bristol-Myers Squibb Company Methods to manipulate quality attributes of polypeptides produced in cho cells
CN109153717A (zh) * 2016-01-06 2019-01-04 安口生物公司 减少单克隆抗体组合物中的高分子量物类、酸性电荷物类和片段
WO2017136433A1 (en) 2016-02-03 2017-08-10 Oncobiologics, Inc. Buffer formulations for enhanced antibody stability
BR112020003122A2 (pt) * 2017-10-16 2020-08-04 Regeneron Pharmaceuticals, Inc. métodos e sistemas para controlar condições de meio de cultura celular e para reduzir modificações pós-translação de uma proteína secretada
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WO2025053166A1 (ja) * 2023-09-05 2025-03-13 味の素株式会社 培地組成物
WO2025142807A1 (ja) * 2023-12-25 2025-07-03 武田薬品工業株式会社 細胞の培養方法

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Also Published As

Publication number Publication date
CR9897A (es) 2008-07-29
BRPI0617744A2 (pt) 2011-08-02
AU2006306433A1 (en) 2007-05-03
DK1941026T3 (da) 2014-07-21
JP2009512459A (ja) 2009-03-26
AR058140A1 (es) 2008-01-23
JP5907928B2 (ja) 2016-04-26
NO20081622L (no) 2008-06-18
IL190550A (en) 2017-01-31
IL190550A0 (en) 2008-11-03
EP1941026B1 (en) 2014-06-04
CN101297027A (zh) 2008-10-29
PE20070796A1 (es) 2007-08-15
PL1941026T3 (pl) 2014-12-31
CN101297027B (zh) 2013-04-03
AU2006306433B2 (en) 2013-04-18
US20070110743A1 (en) 2007-05-17
KR20080063365A (ko) 2008-07-03
HK1120552A1 (zh) 2009-04-03
ES2485374T3 (es) 2014-08-13
CA2627003A1 (en) 2007-05-03
EP1941026A2 (en) 2008-07-09
RU2491347C2 (ru) 2013-08-27
RU2008113220A (ru) 2009-12-10
KR101402634B1 (ko) 2014-06-03
SI1941026T1 (sl) 2014-07-31
ECSP088395A (es) 2008-05-30
NI200800111A (es) 2009-03-03
JP2013165728A (ja) 2013-08-29
PT1941026E (pt) 2014-07-31
WO2007050498A2 (en) 2007-05-03
WO2007050498A3 (en) 2007-07-12
CA2627003C (en) 2018-08-28

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