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TW200630342A - Bengamides with a substituted caprolactam ring, preparation process, compositions containing them and use thereof - Google Patents

Bengamides with a substituted caprolactam ring, preparation process, compositions containing them and use thereof

Info

Publication number
TW200630342A
TW200630342A TW094141643A TW94141643A TW200630342A TW 200630342 A TW200630342 A TW 200630342A TW 094141643 A TW094141643 A TW 094141643A TW 94141643 A TW94141643 A TW 94141643A TW 200630342 A TW200630342 A TW 200630342A
Authority
TW
Taiwan
Prior art keywords
compositions containing
preparation process
bengamides
caprolactam ring
substituted caprolactam
Prior art date
Application number
TW094141643A
Other languages
English (en)
Inventor
Jidong Zhang
Neerja Bhatnagar
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of TW200630342A publication Critical patent/TW200630342A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW094141643A 2004-11-29 2005-11-28 Bengamides with a substituted caprolactam ring, preparation process, compositions containing them and use thereof TW200630342A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0412646A FR2878525B1 (fr) 2004-11-29 2004-11-29 Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation

Publications (1)

Publication Number Publication Date
TW200630342A true TW200630342A (en) 2006-09-01

Family

ID=34954085

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094141643A TW200630342A (en) 2004-11-29 2005-11-28 Bengamides with a substituted caprolactam ring, preparation process, compositions containing them and use thereof

Country Status (17)

Country Link
US (2) US20070249584A1 (zh)
EP (1) EP1819680B1 (zh)
JP (1) JP2008521779A (zh)
KR (1) KR20070089723A (zh)
CN (1) CN101065361A (zh)
AR (1) AR052035A1 (zh)
AT (1) ATE545632T1 (zh)
AU (1) AU2005308709A1 (zh)
BR (1) BRPI0516663A (zh)
CA (1) CA2585990A1 (zh)
FR (1) FR2878525B1 (zh)
IL (1) IL183189A0 (zh)
MX (1) MX2007006042A (zh)
PE (1) PE20061081A1 (zh)
RU (1) RU2007123394A (zh)
TW (1) TW200630342A (zh)
WO (1) WO2006056695A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7153846B2 (en) * 2003-10-24 2006-12-26 Sanofi-Aventis Deutschland Gmbh Bengamide derivatives, process for preparing them, and their use
FR2878525B1 (fr) * 2004-11-29 2007-02-23 Aventis Pharma Sa Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2878528B1 (fr) * 2004-11-29 2008-05-16 Aventis Pharma Sa 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2901556A1 (fr) * 2006-05-24 2007-11-30 Sanofi Aventis Sa Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
FR2901554B1 (fr) * 2006-05-24 2011-04-01 Sanofi Aventis 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation
FR2901555A1 (fr) * 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation
GB2451451A (en) * 2007-07-30 2009-02-04 Inion Ltd Osteogenic compounds
CN101456824B (zh) * 2007-12-11 2013-04-17 中国科学院上海药物研究所 α-氨基-N-取代酰胺化合物、包含该化合物的药物组合物及其用途
CN102911118B (zh) * 2012-11-09 2014-04-09 天津商业大学 一类苯并氮杂卓类衍生物及其制备方法和用途
CN109320456A (zh) * 2018-11-16 2019-02-12 天津商业大学 新晶型的抗肿瘤化合物及其制备方法和含其的组合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692522A (en) 1985-04-01 1987-09-08 Merck & Co., Inc. Benzofused lactams useful as cholecystokinin antagonists
US4831135A (en) 1986-06-18 1989-05-16 The Regents Of The University Of California Bengamide anthelmintics
US5283241A (en) 1992-08-28 1994-02-01 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone
GB9411841D0 (en) 1994-06-14 1994-08-03 Pharma Mar Sa New antitumoral compounds from jaspis sponge
JP2002241368A (ja) 1997-02-18 2002-08-28 Shionogi & Co Ltd 新規ベンゾラクタム誘導体およびそれを含有する医薬組成物
US6239127B1 (en) 1999-11-17 2001-05-29 Novartis Ag Certain substituted caprolactams, pharmaceutical compositions containing them and a process for their preparation
CO5140099A1 (es) * 1998-11-17 2002-03-22 Novartis Ag Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores
ATE383341T1 (de) 2000-05-11 2008-01-15 Novartis Pharma Gmbh Substituierte caprolactam carbonate und ether sowie deren verwendung als anti-tumor wirkstoffe
EP1337854A2 (en) 2000-11-14 2003-08-27 Novartis AG Method for screening anti-proliferative compounds and inhibiting tumor growth
WO2002072555A1 (en) 2001-03-12 2002-09-19 Novartis Ag Process for preparing certain substituted caprolactams
JP2004262793A (ja) * 2003-02-28 2004-09-24 Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai 化合物ｎ−９０１１、その製造法及び用途
MXPA06000975A (es) * 2003-07-25 2006-04-11 Novartis Ag Lactams sustituidos y su uso como agentes anti-cancer.
US7153846B2 (en) 2003-10-24 2006-12-26 Sanofi-Aventis Deutschland Gmbh Bengamide derivatives, process for preparing them, and their use
DE10349669B3 (de) * 2003-10-24 2005-05-25 Aventis Pharma Deutschland Gmbh Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2878528B1 (fr) 2004-11-29 2008-05-16 Aventis Pharma Sa 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2878525B1 (fr) 2004-11-29 2007-02-23 Aventis Pharma Sa Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2901556A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
US20090007597A1 (en) * 2007-07-02 2009-01-08 Hanevold Gail F Body attached band with removal visual image pockets

Also Published As

Publication number Publication date
MX2007006042A (es) 2007-07-10
WO2006056695A8 (fr) 2007-04-05
US7585855B2 (en) 2009-09-08
EP1819680A1 (fr) 2007-08-22
KR20070089723A (ko) 2007-08-31
PE20061081A1 (es) 2006-12-08
FR2878525B1 (fr) 2007-02-23
RU2007123394A (ru) 2009-01-10
US20070249584A1 (en) 2007-10-25
BRPI0516663A (pt) 2008-09-16
CN101065361A (zh) 2007-10-31
FR2878525A1 (fr) 2006-06-02
ATE545632T1 (de) 2012-03-15
US20080318928A1 (en) 2008-12-25
JP2008521779A (ja) 2008-06-26
AU2005308709A1 (en) 2006-06-01
IL183189A0 (en) 2007-08-19
CA2585990A1 (fr) 2006-06-01
AR052035A1 (es) 2007-02-28
EP1819680B1 (fr) 2012-02-15
WO2006056695A1 (fr) 2006-06-01

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