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TR200200995T2 - 7-amino-3-metksimetil-3-sefem-4-karbosilik asitin hazırlanmasına yönelik proses. - Google Patents

7-amino-3-metksimetil-3-sefem-4-karbosilik asitin hazırlanmasına yönelik proses.

Info

Publication number
TR200200995T2
TR200200995T2 TR2002/00995T TR200200995T TR200200995T2 TR 200200995 T2 TR200200995 T2 TR 200200995T2 TR 2002/00995 T TR2002/00995 T TR 2002/00995T TR 200200995 T TR200200995 T TR 200200995T TR 200200995 T2 TR200200995 T2 TR 200200995T2
Authority
TR
Turkey
Prior art keywords
cefem
amino
preparation
carboxylic acid
methymethyl
Prior art date
Application number
TR2002/00995T
Other languages
English (en)
Inventor
Lee Gwan-Sun
Lee Jae-Heon
Chang Young-Kil
Park Chul-Hyun
Park Gha-Seung
Kim Cheol-Kyung
Original Assignee
Hanmi Pharm. Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm. Co., Ltd. filed Critical Hanmi Pharm. Co., Ltd.
Publication of TR200200995T2 publication Critical patent/TR200200995T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Metansülfonik asit varliginda bir trimetil borat ve metanolun azeotropik karisimi ile 7-aminosefalosporanik asitin reaksiyona sokulmasini kapsayan, formül (I)'e ait 7-amino-3-metoksimetil-3-sefem-4-karboksilik asitin hazirlanmasina yönelik bir proses.
TR2002/00995T 1999-10-13 2000-10-13 7-amino-3-metksimetil-3-sefem-4-karbosilik asitin hazırlanmasına yönelik proses. TR200200995T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019990044322A KR100343434B1 (ko) 1999-10-13 1999-10-13 7-아미노-3-메톡시메틸-3-세펨-4-카복실산의 제조방법

Publications (1)

Publication Number Publication Date
TR200200995T2 true TR200200995T2 (tr) 2002-06-21

Family

ID=19615184

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00995T TR200200995T2 (tr) 1999-10-13 2000-10-13 7-amino-3-metksimetil-3-sefem-4-karbosilik asitin hazırlanmasına yönelik proses.

Country Status (14)

Country Link
US (1) US6620930B1 (tr)
EP (1) EP1220859B1 (tr)
JP (1) JP3860750B2 (tr)
KR (1) KR100343434B1 (tr)
CN (1) CN1148371C (tr)
AT (1) ATE260923T1 (tr)
AU (1) AU755155B2 (tr)
BR (1) BR0014727A (tr)
CA (1) CA2387223A1 (tr)
DE (1) DE60008772T2 (tr)
ES (1) ES2213615T3 (tr)
IL (1) IL148978A0 (tr)
TR (1) TR200200995T2 (tr)
WO (1) WO2001027117A1 (tr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN192344B (tr) * 2001-01-30 2004-04-10 Ranbaxy Lab Ltd
WO2004002237A2 (en) 2002-06-26 2004-01-08 Ctb, Inc. Poultry feeder
CN102746322B (zh) * 2012-07-20 2015-06-17 山东睿鹰先锋制药有限公司 头孢中间体7-氨基-3-甲氧甲基-2-头孢烯-2-羧酸的制备方法
WO2017153824A1 (en) 2016-03-07 2017-09-14 Dhanuka Laboratories Ltd. A process for alkylating the hydroxymethyl group at position -3 of cephalosporins
KR101808192B1 (ko) * 2016-08-26 2018-01-18 아미코젠주식회사 7-아미노세팔로스포란산의 고농도 생산 재조합 아크레모니움 크리소제눔 균주의 제조방법 및 이 방법으로 제조된 균주
CN109956958B (zh) * 2019-04-02 2020-06-16 河北合佳医药科技集团股份有限公司 一种7-氨基-3-甲氧基甲基-3-头孢烯-4-羧酸合成方法
CN112480144A (zh) * 2020-12-07 2021-03-12 湖北凌晟药业有限公司 一种7-氨基-3-甲氧甲基-3-头孢烯-4-羧酸的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5896091A (ja) * 1981-12-01 1983-06-07 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリン類の製造法
JP2612493B2 (ja) * 1988-05-24 1997-05-21 旭化成工業株式会社 ３―置換メチル―３―セフェム―４―カルボン酸類の製造方法
EP0485204B1 (en) * 1990-11-07 1995-05-31 Sankyo Company Limited Process for the preparation of 3-alkoxymethyl cephalosporin derivatives
JP3302417B2 (ja) * 1992-11-11 2002-07-15 三共有機合成株式会社 ３−アルコキシメチル−セファロスポリン誘導体の製造法

Also Published As

Publication number Publication date
ATE260923T1 (de) 2004-03-15
DE60008772D1 (de) 2004-04-08
CN1377359A (zh) 2002-10-30
IL148978A0 (en) 2002-11-10
CN1148371C (zh) 2004-05-05
WO2001027117A1 (en) 2001-04-19
JP2003511455A (ja) 2003-03-25
EP1220859A1 (en) 2002-07-10
EP1220859B1 (en) 2004-03-03
AU7966700A (en) 2001-04-23
ES2213615T3 (es) 2004-09-01
US6620930B1 (en) 2003-09-16
AU755155B2 (en) 2002-12-05
JP3860750B2 (ja) 2006-12-20
DE60008772T2 (de) 2004-07-29
EP1220859A4 (en) 2003-04-02
KR100343434B1 (ko) 2002-07-11
KR20010037039A (ko) 2001-05-07
CA2387223A1 (en) 2001-04-19
BR0014727A (pt) 2002-06-25

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