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TR200200985T2 - Pürin türevleri - Google Patents

Pürin türevleri

Info

Publication number
TR200200985T2
TR200200985T2 TR2002/00985T TR200200985T TR200200985T2 TR 200200985 T2 TR200200985 T2 TR 200200985T2 TR 2002/00985 T TR2002/00985 T TR 2002/00985T TR 200200985 T TR200200985 T TR 200200985T TR 200200985 T2 TR200200985 T2 TR 200200985T2
Authority
TR
Turkey
Prior art keywords
purine derivatives
compounds
preparation
adenosine
solvates
Prior art date
Application number
TR2002/00985T
Other languages
English (en)
Inventor
Marina Monaghan Sandra
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of TR200200985T2 publication Critical patent/TR200200985T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)

Abstract

Mevcut bulus formül (I)'e göre olan bilesikler ve bunlarin farmakolojik olarak kabul edilebilir tuzlari ve solvatlari, bunlarin hazirlanmasi için usuller, bunlarin hazirlanmasinda kullanilan ara ürünler ve bu tip bilesikleri içeren bilesimler ve bu tip bilesiklerin adenosin A2a reseptör olarak kullanimi ile ilgilidir.
TR2002/00985T 1999-10-14 2000-10-06 Pürin türevleri TR200200985T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9924363.6A GB9924363D0 (en) 1999-10-14 1999-10-14 Purine derivatives

Publications (1)

Publication Number Publication Date
TR200200985T2 true TR200200985T2 (tr) 2002-10-21

Family

ID=10862760

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00985T TR200200985T2 (tr) 1999-10-14 2000-10-06 Pürin türevleri

Country Status (50)

Country Link
US (1) US6350735B1 (tr)
EP (1) EP1220863B1 (tr)
JP (1) JP3994007B2 (tr)
KR (1) KR20020037774A (tr)
CN (1) CN1151167C (tr)
AP (1) AP1442A (tr)
AR (1) AR023275A1 (tr)
AT (1) ATE238336T1 (tr)
AU (1) AU768308B2 (tr)
BG (1) BG106569A (tr)
BR (1) BR0011776A (tr)
CA (1) CA2387531C (tr)
CO (1) CO5251399A1 (tr)
CR (1) CR6584A (tr)
CZ (1) CZ20021223A3 (tr)
DE (1) DE60002356T2 (tr)
DK (1) DK1220863T3 (tr)
DZ (1) DZ3159A1 (tr)
EA (1) EA004655B1 (tr)
EC (1) ECSP003712A (tr)
EE (1) EE200200193A (tr)
ES (1) ES2193990T3 (tr)
GB (1) GB9924363D0 (tr)
GE (1) GEP20043269B (tr)
GT (1) GT200000172A (tr)
HK (1) HK1047110B (tr)
HN (1) HN2000000204A (tr)
HU (1) HUP0203483A2 (tr)
IL (1) IL146342A0 (tr)
IS (1) IS6165A (tr)
MA (1) MA26828A1 (tr)
MX (1) MXPA02003812A (tr)
MY (1) MY136242A (tr)
NO (1) NO20021692D0 (tr)
NZ (1) NZ515323A (tr)
OA (1) OA12059A (tr)
PA (1) PA8503501A1 (tr)
PE (1) PE20010755A1 (tr)
PL (1) PL354932A1 (tr)
PT (1) PT1220863E (tr)
SI (1) SI1220863T1 (tr)
SK (1) SK4842002A3 (tr)
SV (1) SV2002000198A (tr)
TN (1) TNSN00202A1 (tr)
TR (1) TR200200985T2 (tr)
UA (1) UA66945C2 (tr)
UY (1) UY26397A1 (tr)
WO (1) WO2001027130A1 (tr)
YU (1) YU88901A (tr)
ZA (1) ZA200202849B (tr)

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JP5584138B2 (ja) 2008-01-11 2014-09-03 ノバルティス アーゲー キナーゼ阻害剤としてのピリミジン類
PL2391366T3 (pl) 2009-01-29 2013-04-30 Novartis Ag Podstawione benzimidazole do leczenia gwiaździaków
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
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BR0011776A (pt) 2002-03-12
AU7548800A (en) 2001-04-23
SI1220863T1 (en) 2003-10-31
ZA200202849B (en) 2003-06-25
YU88901A (sh) 2004-09-03
IL146342A0 (en) 2002-07-25
NO20021692L (no) 2002-04-10
AR023275A1 (es) 2002-09-04
DE60002356D1 (de) 2003-05-28
CA2387531A1 (en) 2001-04-19
DZ3159A1 (fr) 2001-04-19
CZ20021223A3 (cs) 2003-05-14
TNSN00202A1 (fr) 2005-11-10
HUP0203483A2 (hu) 2003-02-28
CN1151167C (zh) 2004-05-26
EA004655B1 (ru) 2004-06-24
EP1220863A1 (en) 2002-07-10
GB9924363D0 (en) 1999-12-15
CN1358192A (zh) 2002-07-10
JP3994007B2 (ja) 2007-10-17
GT200000172A (es) 2002-04-05
UA66945C2 (uk) 2004-06-15
SV2002000198A (es) 2002-02-05
PL354932A1 (en) 2004-03-22
NZ515323A (en) 2003-10-31
EA200101107A1 (ru) 2002-10-31
OA12059A (en) 2006-05-03
IS6165A (is) 2001-11-16
WO2001027130A1 (en) 2001-04-19
CR6584A (es) 2004-01-14
AP2002002478A0 (en) 2002-06-30
AU768308B2 (en) 2003-12-04
PE20010755A1 (es) 2001-07-17
CA2387531C (en) 2006-12-05
GEP20043269B (en) 2004-06-25
JP2003511459A (ja) 2003-03-25
PA8503501A1 (es) 2002-02-21
MXPA02003812A (es) 2002-09-30
PT1220863E (pt) 2003-07-31
ATE238336T1 (de) 2003-05-15
HK1047110A1 (en) 2003-02-07
BG106569A (en) 2002-12-29
CO5251399A1 (es) 2003-02-28
ECSP003712A (es) 2002-05-23
HK1047110B (zh) 2005-03-04
UY26397A1 (es) 2001-05-31
DK1220863T3 (da) 2003-08-11
SK4842002A3 (en) 2003-06-03
AP1442A (en) 2005-06-29
US6350735B1 (en) 2002-02-26
EE200200193A (et) 2003-06-16
NO20021692D0 (no) 2002-04-10
MA26828A1 (fr) 2004-12-20
MY136242A (en) 2008-08-29
ES2193990T3 (es) 2003-11-16
HN2000000204A (es) 2001-06-21
EP1220863B1 (en) 2003-04-23
DE60002356T2 (de) 2004-02-19
KR20020037774A (ko) 2002-05-22

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