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TR200103351T2 - Nos inhibitörleri için yeni farmasötik kombinasyonlar. - Google Patents

Nos inhibitörleri için yeni farmasötik kombinasyonlar.

Info

Publication number
TR200103351T2
TR200103351T2 TR2001/03351T TR200103351T TR200103351T2 TR 200103351 T2 TR200103351 T2 TR 200103351T2 TR 2001/03351 T TR2001/03351 T TR 2001/03351T TR 200103351 T TR200103351 T TR 200103351T TR 200103351 T2 TR200103351 T2 TR 200103351T2
Authority
TR
Turkey
Prior art keywords
nos
inhibitors
new pharmaceutical
pharmaceutical combinations
nos inhibitors
Prior art date
Application number
TR2001/03351T
Other languages
English (en)
Inventor
David Saltarelli Mario
Adams Iii Lowe John
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200103351T2 publication Critical patent/TR200103351T2/tr

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
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  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Pyridine Compounds (AREA)
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Abstract

Mevcut bulus, nitrik oksit sentaz (NOS) inhibitörleri etkinligini sergileyen bilesikler için yeni farmasötik kullanimlariyla ilgilidir. Özellikle de sirkadyan ritmi degistirmek suretiyle etkili olan veya kolaylastirilan bir tedavi ile tedavi edilecek bozukluk veya durumlarin tedavisine yönelik olarak NOS inhibitörlerinin kullanimi, özellikle seçici nöronal NOS (nNOS) inhibitörlerinin tek basina veya baska etkin bir madde, özellikle ya bir SSRI veya bir NK-1 alici antagonistle beraber kullanmiyla ilgilidir.
TR2001/03351T 1999-05-21 2000-03-16 Nos inhibitörleri için yeni farmasötik kombinasyonlar. TR200103351T2 (tr)

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DE10001785A1 (de) * 2000-01-18 2001-07-19 Boehringer Ingelheim Pharma NK¶1¶-Rezeptor-Antagonisten zur Behandlung des Restless Legs Syndroms
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US6803470B2 (en) * 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
DOP2002000467A (es) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas
CA2530023A1 (en) * 2003-06-24 2004-12-29 Neurosearch A/S Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP1634598A1 (en) * 2004-09-07 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion
PA8783601A1 (es) 2007-06-08 2009-01-23 Janssen Pharmaceutica Nv Derivados de piperidina/piperazina
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine / piperazine derivatives
WO2008148851A1 (en) 2007-06-08 2008-12-11 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
WO2008148840A1 (en) 2007-06-08 2008-12-11 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
PE20140572A1 (es) 2008-06-05 2014-05-16 Janssen Pharmaceutica Nv Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar
EP2404902A1 (en) 2009-03-05 2012-01-11 Shionogi&Co., Ltd. Piperidine and pyrrolidine derivatives having npy y5 receptor antagonism
EP3610890A1 (en) 2012-11-14 2020-02-19 The Johns Hopkins University Methods and compositions for treating schizophrenia
US20220267269A1 (en) * 2019-06-14 2022-08-25 Srx Cardio, Llc Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (pcsk9)
US12115154B2 (en) 2020-12-16 2024-10-15 Srx Cardio, Llc Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9)

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EE200100611A (et) 2003-02-17
MXPA01011978A (es) 2002-05-06
GT200000071A (es) 2001-11-08
SK16602001A3 (sk) 2003-03-04
HUP0301287A2 (hu) 2003-08-28
AP2001002326A0 (en) 2001-12-31
AR022640A1 (es) 2002-09-04
CN1617743A (zh) 2005-05-18
JP2003523941A (ja) 2003-08-12
PL358538A1 (en) 2004-08-09
KR20020010916A (ko) 2002-02-06
IS6126A (is) 2001-10-26
WO2000071107A2 (en) 2000-11-30
HRP20010862A2 (en) 2003-06-30
CA2374668A1 (en) 2000-11-30
NO20015651D0 (no) 2001-11-20
TNSN00106A1 (fr) 2005-11-10
CO5160295A1 (es) 2002-05-30
NO20015651L (no) 2002-01-18
ZA200109555B (en) 2004-04-07
EA200101110A1 (ru) 2002-08-29
AU2935300A (en) 2000-12-12
OA11943A (en) 2006-04-12
PE20010157A1 (es) 2001-02-16
PA8494601A1 (es) 2002-08-29
EP1178784A1 (en) 2002-02-13
UY26148A1 (es) 2000-12-29
BG106208A (en) 2002-09-30
IL145955A0 (en) 2002-07-25
MA26732A1 (fr) 2004-12-20
BR0010820A (pt) 2002-03-05
WO2000071107A8 (en) 2002-01-24
DZ3041A1 (fr) 2004-03-27
HN2000000045A (es) 2001-03-02
HUP0301287A3 (en) 2005-03-29

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