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TR200103351T2 - New pharmaceutical combinations for nos inhibitors. - Google Patents

New pharmaceutical combinations for nos inhibitors.

Info

Publication number
TR200103351T2
TR200103351T2 TR2001/03351T TR200103351T TR200103351T2 TR 200103351 T2 TR200103351 T2 TR 200103351T2 TR 2001/03351 T TR2001/03351 T TR 2001/03351T TR 200103351 T TR200103351 T TR 200103351T TR 200103351 T2 TR200103351 T2 TR 200103351T2
Authority
TR
Turkey
Prior art keywords
nos
inhibitors
new pharmaceutical
pharmaceutical combinations
nos inhibitors
Prior art date
Application number
TR2001/03351T
Other languages
Turkish (tr)
Inventor
David Saltarelli Mario
Adams Iii Lowe John
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200103351T2 publication Critical patent/TR200103351T2/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/13—Amines
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  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)

Abstract

Mevcut bulus, nitrik oksit sentaz (NOS) inhibitörleri etkinligini sergileyen bilesikler için yeni farmasötik kullanimlariyla ilgilidir. Özellikle de sirkadyan ritmi degistirmek suretiyle etkili olan veya kolaylastirilan bir tedavi ile tedavi edilecek bozukluk veya durumlarin tedavisine yönelik olarak NOS inhibitörlerinin kullanimi, özellikle seçici nöronal NOS (nNOS) inhibitörlerinin tek basina veya baska etkin bir madde, özellikle ya bir SSRI veya bir NK-1 alici antagonistle beraber kullanmiyla ilgilidir.The present invention relates to new pharmaceutical uses for compounds that exhibit the activity of nitric oxide synthase (NOS) inhibitors. The use of NOS inhibitors, especially for the treatment of disorders or conditions to be treated with a treatment that is effective or facilitated by altering the circadian rhythm, a selective or particularly active substance of selective neuronal NOS (nNOS) inhibitors alone or another NK-1. It relates to use with the recipient antagonist.

TR2001/03351T 1999-05-21 2000-03-16 New pharmaceutical combinations for nos inhibitors. TR200103351T2 (en)

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DE10001785A1 (en) * 2000-01-18 2001-07-19 Boehringer Ingelheim Pharma Use of NK-1 receptor antagonists for treatment of restless legs syndrome
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US6803470B2 (en) * 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
DOP2002000467A (en) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-AMINO-6 (PHENYL REPLACED IN POSITIONS 2,4,5) -PIRIDINES
UA82517C2 (en) 2003-06-24 2008-04-25 Ньюросерч А/С Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP1634598A1 (en) * 2004-09-07 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine/Piperazine derivatives
RU2470017C2 (en) 2007-06-08 2012-12-20 Янссен Фармацевтика Н.В. Piperidine/piperazine derivatives
JP5443342B2 (en) 2007-06-08 2014-03-19 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Piperidine / piperazine derivatives
CA2687918C (en) 2007-06-08 2016-11-08 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
ES2617619T3 (en) 2008-06-05 2017-06-19 Janssen Pharmaceutica, N.V. Drug combinations comprising a DGAT inhibitor and a PPAR agonist
WO2010101246A1 (en) 2009-03-05 2010-09-10 塩野義製薬株式会社 Piperidine and pyrrolidine derivatives having npy y5 receptor antagonism
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
CA3142890A1 (en) * 2019-06-14 2020-12-17 Srx Cardio, Llc Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (pcsk9)
US12115154B2 (en) 2020-12-16 2024-10-15 Srx Cardio, Llc Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9)

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WO2000071107A2 (en) 2000-11-30
EP1178784A1 (en) 2002-02-13
PL358538A1 (en) 2004-08-09
UY26148A1 (en) 2000-12-29
JP2003523941A (en) 2003-08-12
NO20015651L (en) 2002-01-18
HUP0301287A2 (en) 2003-08-28
BR0010820A (en) 2002-03-05
HRP20010862A2 (en) 2003-06-30
GT200000071A (en) 2001-11-08
EA200101110A1 (en) 2002-08-29
PE20010157A1 (en) 2001-02-16
AP2001002326A0 (en) 2001-12-31
HUP0301287A3 (en) 2005-03-29
OA11943A (en) 2006-04-12
CN1617743A (en) 2005-05-18
KR20020010916A (en) 2002-02-06
SK16602001A3 (en) 2003-03-04
TNSN00106A1 (en) 2005-11-10
IL145955A0 (en) 2002-07-25
MXPA01011978A (en) 2002-05-06
BG106208A (en) 2002-09-30
NO20015651D0 (en) 2001-11-20
EE200100611A (en) 2003-02-17
AU2935300A (en) 2000-12-12
CO5160295A1 (en) 2002-05-30
ZA200109555B (en) 2004-04-07
IS6126A (en) 2001-10-26
PA8494601A1 (en) 2002-08-29
DZ3041A1 (en) 2004-03-27
HN2000000045A (en) 2001-03-02
MA26732A1 (en) 2004-12-20
WO2000071107A8 (en) 2002-01-24
AR022640A1 (en) 2002-09-04
CA2374668A1 (en) 2000-11-30

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