[go: up one dir, main page]

TR200000419T2 - Feksofenadin ve türevlerinin biyo elde edilebilirliklerinin arttırılması yöntemi. - Google Patents

Feksofenadin ve türevlerinin biyo elde edilebilirliklerinin arttırılması yöntemi.

Info

Publication number
TR200000419T2
TR200000419T2 TR2000/00419T TR200000419T TR200000419T2 TR 200000419 T2 TR200000419 T2 TR 200000419T2 TR 2000/00419 T TR2000/00419 T TR 2000/00419T TR 200000419 T TR200000419 T TR 200000419T TR 200000419 T2 TR200000419 T2 TR 200000419T2
Authority
TR
Turkey
Prior art keywords
bioavailability
fexofenadine
derivatives
increasing
patient
Prior art date
Application number
TR2000/00419T
Other languages
English (en)
Inventor
Hwang Kin-Kai
H. Giesing Dennis
H. Hurst Gail
Original Assignee
Hoechst Marion Roussel, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel, Inc. filed Critical Hoechst Marion Roussel, Inc.
Publication of TR200000419T2 publication Critical patent/TR200000419T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A61K31/75—Polymers of hydrocarbons of ethene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Mevcut bulus, bir hastadaki bir piperidinoalkanol antihistaminin biyo elde edilebilirliginin arttirilmasi için olup söz konusu hastaya söz konusu piperidinoalkanolün etkili bir miktarinin ve p-glikoprotein önleyicinin etkili bir p-glikoprotein önleyici miktarinin birlikte uygulanmasini içeren bir yöntemle ilgilidir.
TR2000/00419T 1997-08-14 1998-07-21 Feksofenadin ve türevlerinin biyo elde edilebilirliklerinin arttırılması yöntemi. TR200000419T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91156397A 1997-08-14 1997-08-14

Publications (1)

Publication Number Publication Date
TR200000419T2 true TR200000419T2 (tr) 2000-09-21

Family

ID=25430473

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00419T TR200000419T2 (tr) 1997-08-14 1998-07-21 Feksofenadin ve türevlerinin biyo elde edilebilirliklerinin arttırılması yöntemi.

Country Status (29)

Country Link
EP (1) EP1003528B1 (tr)
JP (1) JP4295913B2 (tr)
KR (1) KR100522985B1 (tr)
CN (1) CN1143680C (tr)
AR (1) AR018505A1 (tr)
AT (1) ATE224721T1 (tr)
AU (1) AU725965C (tr)
BR (1) BR9811937A (tr)
CA (1) CA2301267C (tr)
CZ (1) CZ293666B6 (tr)
DE (1) DE69808303T2 (tr)
DK (1) DK1003528T3 (tr)
EE (1) EE04263B1 (tr)
ES (1) ES2179523T3 (tr)
HU (1) HU226823B1 (tr)
ID (1) ID24463A (tr)
IL (1) IL134521A (tr)
NO (1) NO325148B1 (tr)
NZ (1) NZ502133A (tr)
OA (1) OA11287A (tr)
PL (1) PL191607B1 (tr)
PT (1) PT1003528E (tr)
RU (1) RU2197967C2 (tr)
SK (1) SK283868B6 (tr)
TR (1) TR200000419T2 (tr)
TW (1) TWI240633B (tr)
UA (1) UA64765C2 (tr)
WO (1) WO1999008690A1 (tr)
ZA (1) ZA987221B (tr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69624559T2 (de) * 1995-02-28 2003-07-10 Aventis Pharmaceuticals Inc., Bridgewater Arzneizubereitungen für piperidinalkanolderivate
DK0998272T3 (da) * 1997-08-26 2003-08-25 Aventis Pharma Inc Farmaceutisk præparat til kombinationen piperidinoalkanoldekongestivum
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
BR0306329A (pt) * 2002-05-29 2005-04-26 Aventis Pharmaceuticals Holdin Método de tratamento de asma
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
PE20060416A1 (es) * 2004-08-03 2006-06-09 Novartis Ag Composicion de inhibidores de renina e inhibidores de proteinas de efusion
JP2008120684A (ja) * 2005-03-07 2008-05-29 Kumamoto Univ 抗アレルギー薬
KR101106374B1 (ko) 2009-06-05 2012-01-19 민병욱 고체연료에 의한 가연성 가스 발생 장치
KR101117014B1 (ko) * 2009-09-09 2012-06-14 민병욱 부패성 폐기물의 바이오매스 처리에 의한 폐자원 재활용 방법 및 장치
CN101843616B (zh) * 2010-06-04 2011-07-27 西安万隆制药有限责任公司 一种盐酸非索非那定与微晶纤维素组合物及其制备方法
RU2453315C2 (ru) * 2010-08-17 2012-06-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения аллергических заболеваний
PH12013502368A1 (en) 2011-05-20 2014-01-06 Aventisub Llc Pharmaceutical composition comprising fexofenadine
RU2504018C1 (ru) * 2012-05-28 2014-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения и социального развития Российской Федерации Способ моделирования состояния индукции функциональной активности гликопротеина-р финастеридом в эксперименте
RU2553362C1 (ru) * 2014-01-09 2015-06-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Способ моделирования состояния ингибирования функциональной активности гликопротеина-р линестренолом в эксперименте
CN104188998A (zh) * 2014-09-18 2014-12-10 中山大学 一种柚皮苷与盐酸非索非那丁药物组合物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
KR910007515A (ko) * 1989-01-31 1991-05-30 호르스트 카베리쯔 부식에 의한 활성제의 서방형 제제 및 그 제조방법
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
WO1996040792A1 (en) * 1995-06-07 1996-12-19 Novo Nordisk A/S Modification of polypeptides
CA2224227A1 (en) * 1995-06-07 1996-12-19 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds

Also Published As

Publication number Publication date
ZA987221B (en) 1999-02-15
OA11287A (en) 2003-10-22
RU2197967C2 (ru) 2003-02-10
EE04263B1 (et) 2004-04-15
CZ293666B6 (cs) 2004-06-16
CN1143680C (zh) 2004-03-31
ES2179523T3 (es) 2003-01-16
DK1003528T3 (da) 2003-02-03
SK283868B6 (sk) 2004-03-02
CZ2000522A3 (cs) 2000-09-13
EP1003528B1 (en) 2002-09-25
CA2301267C (en) 2004-07-13
CN1267221A (zh) 2000-09-20
HU226823B1 (hu) 2009-11-30
KR100522985B1 (ko) 2005-10-21
KR20010022845A (ko) 2001-03-26
CA2301267A1 (en) 1999-02-25
ATE224721T1 (de) 2002-10-15
AU8505098A (en) 1999-03-08
NZ502133A (en) 2002-03-28
PT1003528E (pt) 2003-02-28
TWI240633B (en) 2005-10-01
NO325148B1 (no) 2008-02-11
AR018505A1 (es) 2001-11-28
IL134521A (en) 2005-07-25
BR9811937A (pt) 2000-09-05
HUP0003189A2 (en) 2001-03-28
SK1842000A3 (en) 2000-08-14
PL338579A1 (en) 2000-11-06
PL191607B1 (pl) 2006-06-30
AU725965C (en) 2004-04-22
NO20000706L (no) 2000-04-13
ID24463A (id) 2000-07-20
JP2001515041A (ja) 2001-09-18
HK1025901A1 (en) 2000-12-01
EP1003528A1 (en) 2000-05-31
DE69808303D1 (de) 2002-10-31
DE69808303T2 (de) 2003-05-22
JP4295913B2 (ja) 2009-07-15
NO20000706D0 (no) 2000-02-11
AU725965B2 (en) 2000-10-26
EE200000069A (et) 2000-10-16
HUP0003189A3 (en) 2001-04-28
UA64765C2 (uk) 2004-03-15
IL134521A0 (en) 2001-04-30
WO1999008690A1 (en) 1999-02-25

Similar Documents

Publication Publication Date Title
TR200000419T2 (tr) Feksofenadin ve türevlerinin biyo elde edilebilirliklerinin arttırılması yöntemi.
PT1002795E (pt) Pirimidinas inibidoras da replicacao do hiv
SE9703693D0 (sv) Novel combination
EP1009415A4 (en) INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR
ID22982A (id) PIRAZOL-PIRAZOL TERSUBSTITUSI SEBAGAI INHIBITOR KINASE p38
EE200000488A (et) Fosfolipaasensüümide inhibiitorid ja farmatseutilised kompositsioonid
DE60002193D1 (de) Metalloprotease inhibitoren
DK1133477T3 (da) Substituerede benzimidazoler og deres anvendelse som parpinhibitorer
NO20031843D0 (no) Metylfenidatmodifiserte frigjöringspreparater
DK0958287T3 (da) Sulfamidmetalloprotease-inhibitorer
NO996578D0 (no) Urokinase-inhibitorer
ATE234091T1 (de) Thrombin inhibitoren
TR199903287T2 (tr) Matriks metaloproteinazlarinin ters hidroksamat inhibitörleri.
LU91345I2 (fr) Rufinamide et ses sels pharmaceutiquement acceptables (inovelon)
ATE429224T1 (de) Arzneizubereitungen enthaltend mindestens einen hiv preoteaseinhibitor
NO20015897D0 (no) Indolylpiperidinderivater som antihistaminiske og antiallergiske midler
NO20014243L (no) Dihetero-substituerte metalloproteaseinhibitorer
ATE228760T1 (de) Thrombininhibitoren
DK1214302T3 (da) Substituerede 3-phenyl-5-alkoxy-1,3,4-oxadiazol-2-oner og deres anvendelse som lipasehæmmere
ITBO990293A0 (it) Metodo di controllo di banconote .
FI20011649L (fi) Korkeapaineinen, suurnopeuksinen primäärinen ja sekundäärinen jalostus
TR199800847A3 (tr) Bir anjiyotensin dönüstürücü enzim inhibitörünün sabit doz bilesimi.
ID24224A (id) Turunan-turunan 6-azaurasil sebagai inhibitor il-5
ATE227288T1 (de) Acetylenische ortho-sulfonamido- und phosphinsäure-amido-bicyclische heteroarylhydroxamsäure als tace-inhibitoren
ATE228122T1 (de) Umgekehrt hydroxamat inhibitoren von matrix metalloproteinasen