TR199900326T2 - Üst solunum yollari alerjik tepkisinin histamin reseptör antagonistlerin bir birlesimi ile tedavisi. - Google Patents
Üst solunum yollari alerjik tepkisinin histamin reseptör antagonistlerin bir birlesimi ile tedavisi.Info
- Publication number
- TR199900326T2 TR199900326T2 TR1999/00326T TR9900326T TR199900326T2 TR 199900326 T2 TR199900326 T2 TR 199900326T2 TR 1999/00326 T TR1999/00326 T TR 1999/00326T TR 9900326 T TR9900326 T TR 9900326T TR 199900326 T2 TR199900326 T2 TR 199900326T2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- combination
- receptor antagonists
- upper respiratory
- allergic response
- Prior art date
Links
- 229940122236 Histamine receptor antagonist Drugs 0.000 title 1
- 208000026935 allergic disease Diseases 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 239000002552 dosage form Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229940124056 Histamine H1 receptor antagonist Drugs 0.000 abstract 1
- 229940115480 Histamine H3 receptor antagonist Drugs 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 239000000938 histamine H1 antagonist Substances 0.000 abstract 1
- 239000003395 histamine H3 receptor antagonist Substances 0.000 abstract 1
- 239000000133 nasal decongestant Substances 0.000 abstract 1
- 206010039083 rhinitis Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Rhinitis semptomlarinin yok edilmesi, (a) antihistaminik etkili bir miktarda bir histamin H1 reseptör antagonist ile beraber (b) bir burun dekonjestant etkisini saglamak için yeterli miktarda bir histamin H3 reseptör antagonistin uygulanmasiyla elde edilmektedir. Bilesimler, bilesimlerin ikisininde terapötik sistemik seviyesini ayni düzeyde tutmak amaciyla, toplu halde tek bir dozaj seklinde ya da ayri ayri, ayni ya da farkli dozaj sekillerinde verilebilir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68995196A | 1996-08-16 | 1996-08-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199900326T2 true TR199900326T2 (tr) | 1999-05-21 |
Family
ID=24770500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/00326T TR199900326T2 (tr) | 1996-08-16 | 1997-08-13 | Üst solunum yollari alerjik tepkisinin histamin reseptör antagonistlerin bir birlesimi ile tedavisi. |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0920315B1 (tr) |
| JP (2) | JP3638289B2 (tr) |
| KR (1) | KR20000029975A (tr) |
| CN (1) | CN1152682C (tr) |
| AR (1) | AR008293A1 (tr) |
| AT (1) | ATE314071T1 (tr) |
| AU (1) | AU722040B2 (tr) |
| BR (1) | BR9711149A (tr) |
| CA (1) | CA2263163A1 (tr) |
| CO (1) | CO4910138A1 (tr) |
| CZ (1) | CZ43299A3 (tr) |
| DE (1) | DE69734984D1 (tr) |
| HU (1) | HUP9904362A3 (tr) |
| ID (1) | ID17871A (tr) |
| IL (1) | IL128573A0 (tr) |
| MY (1) | MY116130A (tr) |
| NO (1) | NO990706D0 (tr) |
| NZ (1) | NZ334063A (tr) |
| PE (1) | PE100298A1 (tr) |
| PL (1) | PL191073B1 (tr) |
| SK (1) | SK20099A3 (tr) |
| TR (1) | TR199900326T2 (tr) |
| TW (2) | TWI221768B (tr) |
| WO (1) | WO1998006394A1 (tr) |
| ZA (1) | ZA977263B (tr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ527201A (en) * | 1997-03-26 | 2004-12-24 | Sepracor Inc | Stable norastemizole formulations comprising coated norastemizole particles |
| ID22891A (id) * | 1997-08-26 | 1999-12-16 | Hoechst Marion Roussel Inc | Komposisi farmasi untuk kombinasi piperidinoalkanol-dekongestan |
| US6034251A (en) * | 1997-11-07 | 2000-03-07 | Schering Corporation | Phenyl-alkyl-imidazoles |
| US5990147A (en) * | 1997-11-07 | 1999-11-23 | Schering Corporation | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
| CN1285828A (zh) * | 1997-11-07 | 2001-02-28 | 先灵公司 | 被含有一个氮原子的五、六或七元杂环取代的咪唑基烷基 |
| JP2001522836A (ja) * | 1997-11-07 | 2001-11-20 | シェーリング コーポレイション | H3レセプターアンタゴニストとしてのフェニル−アルキル−イミダゾール |
| CA2308586A1 (en) * | 1997-11-07 | 1999-05-20 | Schering Corporation | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
| US6384038B1 (en) * | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| AU6252699A (en) * | 1998-10-09 | 2000-05-01 | Schering Corporation | Composition and method for treating allergic diseases |
| US6100279A (en) * | 1998-11-05 | 2000-08-08 | Schering Corporation | Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom |
| PE20010752A1 (es) * | 1999-09-22 | 2001-07-17 | Schering Corp | Uso de desloratadina para el tratamiento de estados alergicos e inflamatorios |
| HK1046367A1 (zh) * | 2000-02-03 | 2003-01-10 | Schering Corporation | 治疗过敏和炎症症状 |
| PE20020507A1 (es) | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| GB2373186A (en) * | 2001-02-23 | 2002-09-18 | Astrazeneca Ab | Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation |
| JP4522651B2 (ja) | 2001-03-13 | 2010-08-11 | シェーリング コーポレイション | 新規非イミダゾール化合物 |
| US7105505B2 (en) | 2002-04-18 | 2006-09-12 | Schering Corporation | Benzimidazole derivatives useful as histamine H3 antagonists |
| CA2482551C (en) | 2002-04-18 | 2009-08-11 | Schering Corporation | 1-(4-piperidinyl) benzimidazolones as histamine h3 antagonists |
| AU2003243709B2 (en) | 2002-06-24 | 2007-01-18 | Schering Corporation | Indole derivatives useful as histamine H3 antagonists |
| US20050090527A1 (en) * | 2003-01-28 | 2005-04-28 | Schering Corporation | Combination of H1, H3 and H4 receptor antagonists for treatment of allergic and non-allergic pulmonary inflammation, congestion and allergic rhinitis |
| KR20080021082A (ko) | 2005-06-20 | 2008-03-06 | 쉐링 코포레이션 | 히스타민 h3 길항제로서 유용한 피페리딘 유도체 |
| EP2318388A2 (en) | 2008-07-23 | 2011-05-11 | Schering Corporation | Tricyclic spirocycle derivatives and methods of use thereof |
| EP2350048A2 (en) | 2008-10-16 | 2011-08-03 | Schering Corporation | Azine derivatives and methods of use thereof |
| WO2010071822A1 (en) | 2008-12-19 | 2010-06-24 | Schering Corporation | Piperidine and piperazine derivatives and methods of use thereof |
| US8283360B2 (en) | 2008-12-19 | 2012-10-09 | Merck Sharp & Dohme Corp. | Bicyclic heterocyclic derivatives and methods of use thereof |
| PT2408453T (pt) | 2009-03-17 | 2022-04-05 | Nicox Ophthalmics Inc | Formulações oftálmicas de cetirizina e métodos de utilização |
| US8569273B2 (en) | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
| EP2429530B1 (en) * | 2009-05-14 | 2018-11-07 | The General Hospital Corporation | (s)-meclizine for treating ischaemia-reperfusion injury |
| US8759357B2 (en) | 2009-10-08 | 2014-06-24 | Merck Sharp & Dohme Corp. | Inhibitors of fatty acid binding protein (FABP) |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| RU2685277C1 (ru) * | 2018-05-24 | 2019-04-17 | Общество с ограниченной ответственностью "Фарминтерпрайсез Аллерджи" | Применение бисамидного производного малоновой кислоты для лечения аллергических и других заболеваний человека и животных |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU201683B (en) * | 1987-08-04 | 1990-12-28 | Biogal Gyogyszergyar | Process for producing pharmaceutical compositions for promoting healing of wounds |
| US5019591A (en) * | 1989-02-17 | 1991-05-28 | Pennsylvania Research Corporation | Method for treating retinopathy and other small vessel disorders associated with diabetes |
| GB9303210D0 (en) * | 1993-02-17 | 1993-03-31 | Univ Manitoba | Cancer treatment |
-
1997
- 1997-08-13 AT AT97937153T patent/ATE314071T1/de not_active IP Right Cessation
- 1997-08-13 TW TW086111627A patent/TWI221768B/zh not_active IP Right Cessation
- 1997-08-13 ZA ZA9707263A patent/ZA977263B/xx unknown
- 1997-08-13 PL PL331617A patent/PL191073B1/pl not_active IP Right Cessation
- 1997-08-13 MY MYPI97003708A patent/MY116130A/en unknown
- 1997-08-13 BR BR9711149A patent/BR9711149A/pt not_active Application Discontinuation
- 1997-08-13 TW TW093112764A patent/TW200427450A/zh unknown
- 1997-08-13 KR KR1019997001226A patent/KR20000029975A/ko not_active Abandoned
- 1997-08-13 JP JP50985998A patent/JP3638289B2/ja not_active Expired - Fee Related
- 1997-08-13 NZ NZ334063A patent/NZ334063A/xx unknown
- 1997-08-13 PE PE1997000705A patent/PE100298A1/es not_active Application Discontinuation
- 1997-08-13 TR TR1999/00326T patent/TR199900326T2/tr unknown
- 1997-08-13 IL IL12857397A patent/IL128573A0/xx unknown
- 1997-08-13 CN CNB971987130A patent/CN1152682C/zh not_active Expired - Fee Related
- 1997-08-13 WO PCT/US1997/013903 patent/WO1998006394A1/en not_active Ceased
- 1997-08-13 AU AU39733/97A patent/AU722040B2/en not_active Ceased
- 1997-08-13 HU HU9904362A patent/HUP9904362A3/hu unknown
- 1997-08-13 AR ARP970103693A patent/AR008293A1/es unknown
- 1997-08-13 CZ CZ99432A patent/CZ43299A3/cs unknown
- 1997-08-13 DE DE69734984T patent/DE69734984D1/de not_active Expired - Lifetime
- 1997-08-13 CA CA002263163A patent/CA2263163A1/en not_active Abandoned
- 1997-08-13 SK SK200-99A patent/SK20099A3/sk unknown
- 1997-08-13 EP EP97937153A patent/EP0920315B1/en not_active Expired - Lifetime
- 1997-08-14 CO CO97046887A patent/CO4910138A1/es unknown
- 1997-08-14 ID IDP972837A patent/ID17871A/id unknown
-
1999
- 1999-02-15 NO NO990706A patent/NO990706D0/no unknown
-
2002
- 2002-07-30 JP JP2002222138A patent/JP2003095979A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0920315B1 (en) | 2005-12-28 |
| SK20099A3 (en) | 2000-08-14 |
| ZA977263B (en) | 1998-02-16 |
| HUP9904362A2 (hu) | 2000-11-28 |
| PE100298A1 (es) | 1999-01-11 |
| JP2003095979A (ja) | 2003-04-03 |
| HUP9904362A3 (en) | 2000-12-28 |
| TW200427450A (en) | 2004-12-16 |
| TWI221768B (en) | 2004-10-11 |
| DE69734984D1 (de) | 2006-02-02 |
| MY116130A (en) | 2003-11-28 |
| PL191073B1 (pl) | 2006-03-31 |
| NO990706L (no) | 1999-02-15 |
| AU722040B2 (en) | 2000-07-20 |
| AR008293A1 (es) | 1999-12-29 |
| NO990706D0 (no) | 1999-02-15 |
| EP0920315A1 (en) | 1999-06-09 |
| AU3973397A (en) | 1998-03-06 |
| CO4910138A1 (es) | 2000-04-24 |
| JP3638289B2 (ja) | 2005-04-13 |
| ID17871A (id) | 1998-02-05 |
| CZ43299A3 (cs) | 1999-07-14 |
| ATE314071T1 (de) | 2006-01-15 |
| CN1152682C (zh) | 2004-06-09 |
| KR20000029975A (ko) | 2000-05-25 |
| CN1233179A (zh) | 1999-10-27 |
| PL331617A1 (en) | 1999-08-02 |
| NZ334063A (en) | 2000-09-29 |
| IL128573A0 (en) | 2000-01-31 |
| WO1998006394A1 (en) | 1998-02-19 |
| BR9711149A (pt) | 1999-08-17 |
| CA2263163A1 (en) | 1998-02-19 |
| JP2000505094A (ja) | 2000-04-25 |
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