PE100298A1 - Tratamiento de las respuestas alergicas de la vias respiratorias superiores - Google Patents
Tratamiento de las respuestas alergicas de la vias respiratorias superioresInfo
- Publication number
- PE100298A1 PE100298A1 PE1997000705A PE00070597A PE100298A1 PE 100298 A1 PE100298 A1 PE 100298A1 PE 1997000705 A PE1997000705 A PE 1997000705A PE 00070597 A PE00070597 A PE 00070597A PE 100298 A1 PE100298 A1 PE 100298A1
- Authority
- PE
- Peru
- Prior art keywords
- histamine
- components
- antagonist
- treatment
- entrezos
- Prior art date
Links
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 210000002345 respiratory system Anatomy 0.000 title 1
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 4
- 229940115480 Histamine H3 receptor antagonist Drugs 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 239000002552 dosage form Substances 0.000 abstract 2
- 229960001340 histamine Drugs 0.000 abstract 2
- 239000003395 histamine H3 receptor antagonist Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- MBUVEWMHONZEQD-UHFFFAOYSA-N Azeptin Chemical compound C1CN(C)CCCC1N1C(=O)C2=CC=CC=C2C(CC=2C=CC(Cl)=CC=2)=N1 MBUVEWMHONZEQD-UHFFFAOYSA-N 0.000 abstract 1
- HXRBAVXGYZUSED-UHFFFAOYSA-N Burimamide Chemical compound CNC(=S)NCCCCC1=CN=CN1 HXRBAVXGYZUSED-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- QKDDJDBFONZGBW-UHFFFAOYSA-N N-Cyclohexy-4-(imidazol-4-yl)-1-piperidinecarbothioamide Chemical compound C1CC(C=2NC=NC=2)CCN1C(=S)NC1CCCCC1 QKDDJDBFONZGBW-UHFFFAOYSA-N 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- GXDALQBWZGODGZ-UHFFFAOYSA-N astemizole Chemical compound C1=CC(OC)=CC=C1CCN1CCC(NC=2N(C3=CC=CC=C3N=2)CC=2C=CC(F)=CC=2)CC1 GXDALQBWZGODGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960000383 azatadine Drugs 0.000 abstract 1
- SEBMTIQKRHYNIT-UHFFFAOYSA-N azatadine Chemical compound C1CN(C)CCC1=C1C2=NC=CC=C2CCC2=CC=CC=C21 SEBMTIQKRHYNIT-UHFFFAOYSA-N 0.000 abstract 1
- 229960004574 azelastine Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- MZCJWLAXZRFUPI-UHFFFAOYSA-N impentamine Chemical compound NCCCCCC1=CN=CN1 MZCJWLAXZRFUPI-UHFFFAOYSA-N 0.000 abstract 1
- MURRAGMMNAYLNA-UHFFFAOYSA-N impromidine Chemical compound N1C=NC(CSCCNC(N)=NCCCC=2NC=NC=2)=C1C MURRAGMMNAYLNA-UHFFFAOYSA-N 0.000 abstract 1
- 229950005073 impromidine Drugs 0.000 abstract 1
- 239000008297 liquid dosage form Substances 0.000 abstract 1
- 229960003088 loratadine Drugs 0.000 abstract 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 abstract 1
- 206010039083 rhinitis Diseases 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE: A) UNA CANTIDAD ANTIHISTAMINICA EFICAZ DE UN ANTAGONISTA RECEPTOR DE HISTAMINA H1 QUE SE SELECCIONA DEL GRUPO CONFORMADO POR: ASTEMIZOL, AZATADINA, AZELASTINA, ACRIVASTINA, LORATADINA, ENTRE OTROS, Y MEZCLAS DE LOS MISMOS; Y B) UNA CANTIDAD SUFICIENTE DE UN ANTAGONISTA RECEPTOR DE HISTAMINA H3, QUE SE SELECCIONA DEL GRUPO CONFORMADO POR: TIOPERAMIDA, IMPROMIDINA, BURIMAMIDA, IMPENTAMINA, ENTRE OTROS, Y MEZCLAS DE DOS O MAS DE LOS MISMOS, PARA PROVEER UN EFECTO DESCONGESTIVO NASAL; EN UN PORTADOR FARMACEUTICAMENTE ACEPTABLE; DONDE DICHOS COMPONENTES SE PUEDEN COMBINAR EN UNA FORMA DE DOSIFICACION SOLIDA O LIQUIDA. SE REFIERE TAMBIEN A UN METODO PARA ALIVIAR LOS SINTOMAS DE RINITIS EN UN MAMIFERO QUE COMPRENDE MANTENER SIMULTANEAMENTE EN EL SISTEMA CIRCULATORIO: A) UN ANTAGONISTA RECEPTOR DE HISTAMINA H1; Y B) UN ANTAGONISTA RECEPTOR DE HISTAMINA H3; DONDE DICHOS COMPONENTES PUEDEN ADMINISTRARSE EN FORMA DE DOSIFICACION CONJUNTA UNICA, O POR SEPARADO EN FORMAS DE DOSIFICACION IGUALES O DIFERENTES PARA MANTENER LOS NIVELES SISTEMICOS TERAPEUTICOS DE AMBOS COMPONENTES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68995196A | 1996-08-16 | 1996-08-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE100298A1 true PE100298A1 (es) | 1999-01-11 |
Family
ID=24770500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997000705A PE100298A1 (es) | 1996-08-16 | 1997-08-13 | Tratamiento de las respuestas alergicas de la vias respiratorias superiores |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0920315B1 (es) |
| JP (2) | JP3638289B2 (es) |
| KR (1) | KR20000029975A (es) |
| CN (1) | CN1152682C (es) |
| AR (1) | AR008293A1 (es) |
| AT (1) | ATE314071T1 (es) |
| AU (1) | AU722040B2 (es) |
| BR (1) | BR9711149A (es) |
| CA (1) | CA2263163A1 (es) |
| CO (1) | CO4910138A1 (es) |
| CZ (1) | CZ43299A3 (es) |
| DE (1) | DE69734984D1 (es) |
| HU (1) | HUP9904362A3 (es) |
| ID (1) | ID17871A (es) |
| IL (1) | IL128573A0 (es) |
| MY (1) | MY116130A (es) |
| NO (1) | NO990706L (es) |
| NZ (1) | NZ334063A (es) |
| PE (1) | PE100298A1 (es) |
| PL (1) | PL191073B1 (es) |
| SK (1) | SK20099A3 (es) |
| TR (1) | TR199900326T2 (es) |
| TW (2) | TWI221768B (es) |
| WO (1) | WO1998006394A1 (es) |
| ZA (1) | ZA977263B (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010005746A (ko) * | 1997-03-26 | 2001-01-15 | 더글라스이.리디치 | 화학적, 열적으로 안정적인 노라스테미졸 조성물 |
| SK283803B6 (sk) * | 1997-08-26 | 2004-02-03 | Aventis Pharmaceuticals Inc. | Farmaceutický prostriedok vo forme dvojvrstvovej tabletky na kombinovanie piperidinoalkanolu s dekongestantom |
| US6034251A (en) * | 1997-11-07 | 2000-03-07 | Schering Corporation | Phenyl-alkyl-imidazoles |
| JP2001522845A (ja) * | 1997-11-07 | 2001-11-20 | シェーリング コーポレイション | １個の窒素原子を含有する５、６、または７員複素環式環で置換されたイミダゾイルアルキル |
| US5990147A (en) * | 1997-11-07 | 1999-11-23 | Schering Corporation | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
| KR20010031724A (ko) * | 1997-11-07 | 2001-04-16 | 둘락 노먼 씨. | 페닐-알킬-이미다졸 유형의 ｈ₃ 수용체 리간드 |
| ES2188029T3 (es) * | 1997-11-07 | 2003-06-16 | Schering Corp | Fenil-alquil-imidazoles como antagonistas del receptor h3. |
| US6384038B1 (en) * | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| CA2346227A1 (en) * | 1998-10-09 | 2000-04-20 | Schering Corporation | Composition and method for treating allergic diseases |
| US6100279A (en) * | 1998-11-05 | 2000-08-08 | Schering Corporation | Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom |
| PE20010752A1 (es) * | 1999-09-22 | 2001-07-17 | Schering Corp | Uso de desloratadina para el tratamiento de estados alergicos e inflamatorios |
| WO2001056571A1 (en) | 2000-02-03 | 2001-08-09 | Schering Corporation | Treating allergic and inflammatory conditions |
| PE20020507A1 (es) | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| GB2373186A (en) * | 2001-02-23 | 2002-09-18 | Astrazeneca Ab | Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation |
| US6849621B2 (en) | 2001-03-13 | 2005-02-01 | Schering Corporation | Piperidine compounds |
| NZ535764A (en) | 2002-04-18 | 2007-10-26 | Schering Corp | 1-(4-piperidinyl) benzimidazolones as histamine H3 antagonists |
| US7105505B2 (en) | 2002-04-18 | 2006-09-12 | Schering Corporation | Benzimidazole derivatives useful as histamine H3 antagonists |
| JP4326468B2 (ja) | 2002-06-24 | 2009-09-09 | シェーリング コーポレイション | ヒスタミンｈ３アンタゴニストとして有用なインドール誘導体 |
| US20050090527A1 (en) * | 2003-01-28 | 2005-04-28 | Schering Corporation | Combination of H1, H3 and H4 receptor antagonists for treatment of allergic and non-allergic pulmonary inflammation, congestion and allergic rhinitis |
| US7635705B2 (en) | 2005-06-20 | 2009-12-22 | Schering Corporation | Heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists |
| EP2318388A2 (en) | 2008-07-23 | 2011-05-11 | Schering Corporation | Tricyclic spirocycle derivatives and methods of use thereof |
| JP2012505899A (ja) | 2008-10-16 | 2012-03-08 | シェーリング コーポレイション | アジン誘導体およびそれの使用方法 |
| WO2010071822A1 (en) | 2008-12-19 | 2010-06-24 | Schering Corporation | Piperidine and piperazine derivatives and methods of use thereof |
| US8283360B2 (en) | 2008-12-19 | 2012-10-09 | Merck Sharp & Dohme Corp. | Bicyclic heterocyclic derivatives and methods of use thereof |
| MX2011009802A (es) | 2009-03-17 | 2011-11-02 | Aciex Therapeutics Inc | Formulaciones oftalmicas de cetirizina y metodos de uso. |
| US8569273B2 (en) | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
| CN102573847A (zh) * | 2009-05-14 | 2012-07-11 | 总医院公司 | 治疗退化性及缺血性疾病的方法和组合物 |
| EP2485735B1 (en) | 2009-10-08 | 2015-07-29 | Merck Sharp & Dohme Corp. | Inhibitors of fatty acid binding protein (fabp) |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| RU2685277C1 (ru) * | 2018-05-24 | 2019-04-17 | Общество с ограниченной ответственностью "Фарминтерпрайсез Аллерджи" | Применение бисамидного производного малоновой кислоты для лечения аллергических и других заболеваний человека и животных |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU201683B (en) * | 1987-08-04 | 1990-12-28 | Biogal Gyogyszergyar | Process for producing pharmaceutical compositions for promoting healing of wounds |
| US5019591A (en) * | 1989-02-17 | 1991-05-28 | Pennsylvania Research Corporation | Method for treating retinopathy and other small vessel disorders associated with diabetes |
| GB9303210D0 (en) * | 1993-02-17 | 1993-03-31 | Univ Manitoba | Cancer treatment |
-
1997
- 1997-08-13 TW TW086111627A patent/TWI221768B/zh not_active IP Right Cessation
- 1997-08-13 CN CNB971987130A patent/CN1152682C/zh not_active Expired - Fee Related
- 1997-08-13 NZ NZ334063A patent/NZ334063A/xx unknown
- 1997-08-13 CA CA002263163A patent/CA2263163A1/en not_active Abandoned
- 1997-08-13 ZA ZA9707263A patent/ZA977263B/xx unknown
- 1997-08-13 CZ CZ99432A patent/CZ43299A3/cs unknown
- 1997-08-13 MY MYPI97003708A patent/MY116130A/en unknown
- 1997-08-13 SK SK200-99A patent/SK20099A3/sk unknown
- 1997-08-13 PL PL331617A patent/PL191073B1/pl not_active IP Right Cessation
- 1997-08-13 PE PE1997000705A patent/PE100298A1/es not_active Application Discontinuation
- 1997-08-13 EP EP97937153A patent/EP0920315B1/en not_active Expired - Lifetime
- 1997-08-13 IL IL12857397A patent/IL128573A0/xx unknown
- 1997-08-13 KR KR1019997001226A patent/KR20000029975A/ko not_active Abandoned
- 1997-08-13 JP JP50985998A patent/JP3638289B2/ja not_active Expired - Fee Related
- 1997-08-13 HU HU9904362A patent/HUP9904362A3/hu unknown
- 1997-08-13 AU AU39733/97A patent/AU722040B2/en not_active Ceased
- 1997-08-13 DE DE69734984T patent/DE69734984D1/de not_active Expired - Lifetime
- 1997-08-13 TW TW093112764A patent/TW200427450A/zh unknown
- 1997-08-13 BR BR9711149A patent/BR9711149A/pt not_active Application Discontinuation
- 1997-08-13 TR TR1999/00326T patent/TR199900326T2/xx unknown
- 1997-08-13 AR ARP970103693A patent/AR008293A1/es unknown
- 1997-08-13 WO PCT/US1997/013903 patent/WO1998006394A1/en not_active Ceased
- 1997-08-13 AT AT97937153T patent/ATE314071T1/de not_active IP Right Cessation
- 1997-08-14 CO CO97046887A patent/CO4910138A1/es unknown
- 1997-08-14 ID IDP972837A patent/ID17871A/id unknown
-
1999
- 1999-02-15 NO NO990706A patent/NO990706L/no unknown
-
2002
- 2002-07-30 JP JP2002222138A patent/JP2003095979A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP3638289B2 (ja) | 2005-04-13 |
| EP0920315A1 (en) | 1999-06-09 |
| TR199900326T2 (xx) | 1999-05-21 |
| SK20099A3 (en) | 2000-08-14 |
| WO1998006394A1 (en) | 1998-02-19 |
| NZ334063A (en) | 2000-09-29 |
| HUP9904362A3 (en) | 2000-12-28 |
| NO990706D0 (no) | 1999-02-15 |
| JP2003095979A (ja) | 2003-04-03 |
| ZA977263B (en) | 1998-02-16 |
| AU722040B2 (en) | 2000-07-20 |
| EP0920315B1 (en) | 2005-12-28 |
| ID17871A (id) | 1998-02-05 |
| JP2000505094A (ja) | 2000-04-25 |
| CO4910138A1 (es) | 2000-04-24 |
| NO990706L (no) | 1999-02-15 |
| TWI221768B (en) | 2004-10-11 |
| PL191073B1 (pl) | 2006-03-31 |
| CN1233179A (zh) | 1999-10-27 |
| HUP9904362A2 (hu) | 2000-11-28 |
| AU3973397A (en) | 1998-03-06 |
| IL128573A0 (en) | 2000-01-31 |
| CA2263163A1 (en) | 1998-02-19 |
| ATE314071T1 (de) | 2006-01-15 |
| TW200427450A (en) | 2004-12-16 |
| KR20000029975A (ko) | 2000-05-25 |
| CN1152682C (zh) | 2004-06-09 |
| PL331617A1 (en) | 1999-08-02 |
| BR9711149A (pt) | 1999-08-17 |
| AR008293A1 (es) | 1999-12-29 |
| DE69734984D1 (de) | 2006-02-02 |
| MY116130A (en) | 2003-11-28 |
| CZ43299A3 (cs) | 1999-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |