TR199701497T1 - Beyin ödemini önleyen terkip. - Google Patents
Beyin ödemini önleyen terkip.Info
- Publication number
- TR199701497T1 TR199701497T1 TR97/01497T TR9701497T TR199701497T1 TR 199701497 T1 TR199701497 T1 TR 199701497T1 TR 97/01497 T TR97/01497 T TR 97/01497T TR 9701497 T TR9701497 T TR 9701497T TR 199701497 T1 TR199701497 T1 TR 199701497T1
- Authority
- TR
- Turkey
- Prior art keywords
- endothelin antagonist
- treating
- brain edemas
- edemas
- composition
- Prior art date
Links
- 208000014644 Brain disease Diseases 0.000 title 1
- 206010048962 Brain oedema Diseases 0.000 abstract 5
- 208000006752 brain edema Diseases 0.000 abstract 5
- 239000002308 endothelin receptor antagonist Substances 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960003065 bosentan Drugs 0.000 abstract 1
- SXTRWVVIEPWAKM-UHFFFAOYSA-N bosentan hydrate Chemical compound O.COC1=CC=CC=C1OC(C(=NC(=N1)C=2N=CC=CN=2)OCCO)=C1NS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1 SXTRWVVIEPWAKM-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Bu bulus, beyin ödemlerinin tedavisi- veya önlenmesi için, aktif bir madde olarak bir endotelin antagonist içeren bir terkip ile örnegin, asagidaki formül (I) bilesimi; veya onun farmasötik olarak kabul edilebilir tuzlari veya hidratlari; bosentan, sislo
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16006095 | 1995-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199701497T1 true TR199701497T1 (tr) | 1998-06-22 |
Family
ID=15707042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR97/01497T TR199701497T1 (tr) | 1995-06-02 | 1996-05-29 | Beyin ödemini önleyen terkip. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5945448A (tr) |
| EP (1) | EP0838223B1 (tr) |
| JP (1) | JP4011114B2 (tr) |
| KR (1) | KR100399797B1 (tr) |
| CN (1) | CN1083261C (tr) |
| AT (1) | ATE245447T1 (tr) |
| AU (1) | AU700182B2 (tr) |
| BR (1) | BR9608413A (tr) |
| CA (1) | CA2218028C (tr) |
| DE (1) | DE69629195T2 (tr) |
| DK (1) | DK0838223T3 (tr) |
| ES (1) | ES2202449T3 (tr) |
| PT (1) | PT838223E (tr) |
| TR (1) | TR199701497T1 (tr) |
| TW (1) | TW460286B (tr) |
| WO (1) | WO1996038173A1 (tr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482857B1 (en) | 1998-07-17 | 2002-11-19 | The University Of Texas Southwestern Medical Center | Compositions which contain triterpenes for regulating hair growth |
| US6124362A (en) | 1998-07-17 | 2000-09-26 | The Procter & Gamble Company | Method for regulating hair growth |
| TWI232102B (en) * | 2001-07-17 | 2005-05-11 | Shionogi & Co | A pharmaceutical formulation for injection |
| JP2007217438A (ja) * | 2001-07-17 | 2007-08-30 | Shionogi & Co Ltd | 注射用医薬製剤 |
| US20040138187A1 (en) | 2002-08-28 | 2004-07-15 | Reading Christopher L. | Therapeutic treatment methods |
| WO2006098800A1 (en) | 2005-01-14 | 2006-09-21 | Airlite Plastics Co. | Insulated foam panel forms |
| RU2008136317A (ru) * | 2006-03-13 | 2010-04-20 | Инсайсив Фармасьютикалз, Инк. (US) | Способы и композиции для лечения диагностикой сердечной недостаточности |
| US8071596B2 (en) | 2007-01-12 | 2011-12-06 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
| US8080549B2 (en) | 2007-01-12 | 2011-12-20 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
| CA2793668A1 (en) | 2011-10-31 | 2013-04-30 | Bradley J. Crosby | An apparatus and method for construction of structures utilizing insulated concrete forms |
| CA2801735C (en) | 2012-01-13 | 2019-08-06 | Bradley J. Crosby | An apparatus and method for construction of structures utilizing insulated concrete forms |
| USD713975S1 (en) | 2012-07-30 | 2014-09-23 | Airlite Plastics Co. | Insulative insert for insulated concrete form |
| US10787827B2 (en) | 2016-11-14 | 2020-09-29 | Airlite Plastics Co. | Concrete form with removable sidewall |
| CA3061942A1 (en) | 2018-11-19 | 2020-05-19 | Bradley J. Crosby | Concrete form with removable sidewall |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992012991A1 (fr) * | 1991-01-29 | 1992-08-06 | Shionogi Seiyaku Kabushiki Kaisha | Derive de triterpene |
| TW272974B (tr) * | 1993-06-11 | 1996-03-21 | Shionogi & Co | |
| US5599811A (en) * | 1995-02-21 | 1997-02-04 | Warner-Lambert Company | Benzothiazine dioxides as endothelin antagonists |
-
1996
- 1996-05-29 CA CA2218028A patent/CA2218028C/en not_active Expired - Fee Related
- 1996-05-29 BR BR9608413A patent/BR9608413A/pt not_active Application Discontinuation
- 1996-05-29 EP EP96919984A patent/EP0838223B1/en not_active Expired - Lifetime
- 1996-05-29 KR KR1019970707867A patent/KR100399797B1/ko not_active Expired - Fee Related
- 1996-05-29 TR TR97/01497T patent/TR199701497T1/tr unknown
- 1996-05-29 DK DK96919984T patent/DK0838223T3/da active
- 1996-05-29 ES ES96919984T patent/ES2202449T3/es not_active Expired - Lifetime
- 1996-05-29 AT AT96919984T patent/ATE245447T1/de not_active IP Right Cessation
- 1996-05-29 PT PT96919984T patent/PT838223E/pt unknown
- 1996-05-29 AU AU58440/96A patent/AU700182B2/en not_active Ceased
- 1996-05-29 DE DE69629195T patent/DE69629195T2/de not_active Expired - Lifetime
- 1996-05-29 WO PCT/JP1996/001438 patent/WO1996038173A1/ja not_active Ceased
- 1996-05-29 JP JP53636696A patent/JP4011114B2/ja not_active Expired - Fee Related
- 1996-05-29 US US08/930,827 patent/US5945448A/en not_active Expired - Lifetime
- 1996-05-29 CN CN96194363A patent/CN1083261C/zh not_active Expired - Fee Related
- 1996-06-01 TW TW085106558A patent/TW460286B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69629195D1 (de) | 2003-08-28 |
| BR9608413A (pt) | 1998-12-29 |
| KR100399797B1 (ko) | 2004-04-13 |
| CN1083261C (zh) | 2002-04-24 |
| ATE245447T1 (de) | 2003-08-15 |
| US5945448A (en) | 1999-08-31 |
| AU700182B2 (en) | 1998-12-24 |
| ES2202449T3 (es) | 2004-04-01 |
| PT838223E (pt) | 2003-12-31 |
| DK0838223T3 (da) | 2003-11-17 |
| DE69629195T2 (de) | 2004-05-06 |
| CA2218028C (en) | 2010-07-06 |
| CN1186441A (zh) | 1998-07-01 |
| TW460286B (en) | 2001-10-21 |
| AU5844096A (en) | 1996-12-18 |
| WO1996038173A1 (en) | 1996-12-05 |
| KR19990008341A (ko) | 1999-01-25 |
| CA2218028A1 (en) | 1996-12-05 |
| MX9708920A (es) | 1998-03-31 |
| EP0838223A1 (en) | 1998-04-29 |
| EP0838223B1 (en) | 2003-07-23 |
| JP4011114B2 (ja) | 2007-11-21 |
| EP0838223A4 (en) | 2001-04-25 |
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