TR199700020T1 - (-) - (3R) -3-methyl-4- £ 4- £ 4- (4-pyridyl) piperazin-1-yl- | phenoxy | butyric acid as cellular adhesion inhibitor. - Google Patents

(-) - (3R) -3-methyl-4- £ 4- £ 4- (4-pyridyl) piperazin-1-yl- | phenoxy | butyric acid as cellular adhesion inhibitor.

Info

Publication number: TR199700020T1
Authority: TR; Turkey
Prior art keywords: piperazin; phenoxy; pyridyl; methyl; butyric acid
Prior art date: 1995-06-01

Application number

TR97/00020T

Other languages

Turkish (tr)

Inventor

Stuart Dennett Mills

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-01

Filing date

1996-05-28

Publication date

1997-04-22

1995-06-01 Priority claimed from US08/457,538 external-priority patent/US5652242A/en

1995-09-07 Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en

1996-05-28 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1997-04-22 Publication of TR199700020T1 publication Critical patent/TR199700020T1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

TR97/00020T 1995-06-01 1996-05-28 (-) - (3R) -3-methyl-4- £ 4- £ 4- (4-pyridyl) piperazin-1-yl- | phenoxy | butyric acid as cellular adhesion inhibitor. TR199700020T1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/457,538 US5652242A (en)	1993-03-29	1995-06-01	Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en)	1995-09-07	1995-09-07	Optically active derivative

Publications (1)

Publication Number	Publication Date
TR199700020T1 true TR199700020T1 (en)	1997-04-22

Family

ID=26307696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TR97/00020T TR199700020T1 (en)	1995-06-01	1996-05-28	(-) - (3R) -3-methyl-4- £ 4- £ 4- (4-pyridyl) piperazin-1-yl- \| phenoxy \| butyric acid as cellular adhesion inhibitor.

Country Status (31)

Country	Link
EP (1)	EP0796247A1 (en)
JP (1)	JP2885941B2 (en)
KR (1)	KR100245957B1 (en)
AT (1)	AT406675B (en)
AU (1)	AU710105B2 (en)
BE (1)	BE1009520A5 (en)
BR (1)	BR9606409A (en)
CA (1)	CA2194397A1 (en)
CH (1)	CH691808A5 (en)
CZ (1)	CZ26997A3 (en)
DE (1)	DE19680509T1 (en)
DK (1)	DK10697A (en)
ES (1)	ES2137886B1 (en)
FI (1)	FI970393A7 (en)
GB (1)	GB2304340B (en)
GR (1)	GR1002702B (en)
HU (1)	HUP9700274A3 (en)
IE (1)	IE960405A1 (en)
IL (1)	IL118477A0 (en)
IT (1)	IT1290839B1 (en)
LU (1)	LU90008B1 (en)
MC (1)	MC2418A1 (en)
MX (1)	MX9700379A (en)
NL (1)	NL1003243C2 (en)
NO (1)	NO307460B1 (en)
NZ (1)	NZ308597A (en)
PL (1)	PL318440A1 (en)
SE (1)	SE510812C2 (en)
SK (1)	SK13097A3 (en)
TR (1)	TR199700020T1 (en)
WO (1)	WO1996038416A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0100158A3 (en) *	1982-07-28	1985-03-27	The Upjohn Company	(3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) *	1986-04-19	1986-05-21	Pfizer Ltd	Anti-arrhythmia agents
NZ262941A (en) *	1993-03-29	1997-07-27	Zeneca Ltd	Pyridine derivatives and medicaments
GB9406144D0 (en) *	1993-03-29	1994-05-18	Zeneca Ltd	Heterocyclic compounds

1996
- 1996-05-28 FI FI970393A patent/FI970393A7/en unknown
- 1996-05-28 JP JP8536281A patent/JP2885941B2/en not_active Expired - Fee Related
- 1996-05-28 DE DE19680509T patent/DE19680509T1/en not_active Withdrawn
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/en not_active Expired - Fee Related
- 1996-05-28 GR GR960100176A patent/GR1002702B/en not_active IP Right Cessation
- 1996-05-28 SK SK130-97A patent/SK13097A3/en unknown
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/en unknown
- 1996-05-28 ES ES009750006A patent/ES2137886B1/en not_active Expired - Fee Related
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 PL PL96318440A patent/PL318440A1/en unknown
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/en unknown
- 1996-05-28 MX MX9700379A patent/MX9700379A/en unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/en unknown
- 1996-05-28 CH CH00224/97A patent/CH691808A5/en not_active IP Right Cessation
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active Ceased
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 EP EP96919906A patent/EP0796247A1/en not_active Withdrawn
- 1996-05-28 AT AT0900596A patent/AT406675B/en active
- 1996-05-28 BR BR9606409A patent/BR9606409A/en not_active Application Discontinuation
- 1996-05-29 MC MC2347A patent/MC2418A1/en unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/en unknown
- 1996-05-31 NL NL1003243A patent/NL1003243C2/en not_active IP Right Cessation
- 1996-05-31 BE BE9600491A patent/BE1009520A5/en not_active IP Right Cessation
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/en active IP Right Grant
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/en active
- 1997-01-24 SE SE9700203A patent/SE510812C2/en not_active IP Right Cessation
- 1997-01-30 DK DK010697A patent/DK10697A/en not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU710105B2 (en)	1999-09-16
MX9700379A (en)	1997-04-30
NO970437D0 (en)	1997-01-31
BE1009520A5 (en)	1997-04-01
IE960405A1 (en)	1996-12-11
FI970393L (en)	1997-01-30
PL318440A1 (en)	1997-06-09
NO970437L (en)	1997-02-20
CH691808A5 (en)	2001-10-31
DK10697A (en)	1997-04-01
AT406675B (en)	2000-07-25
CA2194397A1 (en)	1996-12-05
LU90008B1 (en)	1997-04-16
CZ26997A3 (en)	1997-08-13
EP0796247A1 (en)	1997-09-24
IT1290839B1 (en)	1998-12-14
GB2304340B (en)	1998-07-29
HUP9700274A2 (en)	1999-06-28
BR9606409A (en)	1997-09-30
NL1003243C2 (en)	1996-12-04
GB2304340A (en)	1997-03-19
JPH09512836A (en)	1997-12-22
ATA900596A (en)	1999-12-15
HUP9700274A3 (en)	2000-02-28
HU9700274D0 (en)	1997-04-28
SE510812C2 (en)	1999-06-28
ITMI961113A0 (en)	1996-05-31
ITMI961113A1 (en)	1997-12-01
ES2137886A1 (en)	1999-12-16
SE9700203L (en)	1997-01-24
FI970393A0 (en)	1997-01-30
AU5827296A (en)	1996-12-18
IL118477A0 (en)	1996-09-12
NZ308597A (en)	1998-11-25
KR100245957B1 (en)	2000-04-01
JP2885941B2 (en)	1999-04-26
GR1002702B (en)	1997-05-22
ES2137886B1 (en)	2000-08-16
MC2418A1 (en)	1997-05-23
GB9627127D0 (en)	1997-02-19
FI970393A7 (en)	1997-01-30
SE9700203D0 (en)	1997-01-24
DE19680509T1 (en)	1997-12-04
NO307460B1 (en)	2000-04-10
WO1996038416A1 (en)	1996-12-05
SK13097A3 (en)	1997-08-06
KR970704689A (en)	1997-09-06

Publication	Publication Date	Title
MX9705005A (en)	1998-07-31	MICROSOMIC TRIGLYCERIDE TRANSFER PROTEIN INHIBITORS AND METHOD.
DE19680255T1 (en)	1997-06-05	Rotamase enzyme activity inhibitors
FI965019A7 (en)	1996-12-13	Enzyme inhibitors
NO974213L (en)	1997-12-04	Small molecular inhibitors of rotamase enzyme activity
TR199501472A2 (en)	1996-07-21	Matrix metalloprotease inhibitors.
NO20006718D0 (en)	2000-12-29	protease inhibitors
DE69522690D1 (en)	2001-10-18	alpha-ketogultaric acid dehydrogenase gene
DK0925303T3 (en)	2003-02-24	Phosphinic acid amides as matrix metalloprotease inhibitors
NO993587D0 (en)	1999-07-22	Sulfonamide metalloprotease inhibitors
FR2769318B1 (en)	1999-12-10	HYDROPHOBIC COATING, ESPECIALLY FOR GLAZING
TR199501451A2 (en)	1996-07-21	£ 2- (2-alkoxy-6-trifluormetilpirimi-4-yl) oxymethyl AN) \| -phenyl-acetic acid derivatives, methods and intermediates for their production and their use.
EE9900180A (en)	1999-12-15	Substituted 4-Biphenyl-4-hydroxybutanoic Acid Derivatives as Metalloprotease Matrix Inhibitors
NO911459D0 (en)	1991-04-15	USE OF METALLION COMPLEXS AS INVESTMENT INHIBITORS.
BR9610075A (en)	1999-03-02	Prolyl endopeptidase inhibitors
TR199700020T1 (en)	1997-04-22	(-) - (3R) -3-methyl-4- £ 4- £ 4- (4-pyridyl) piperazin-1-yl- \| phenoxy \| butyric acid as cellular adhesion inhibitor.
TR199600607A2 (en)	1997-02-21	Para-hydroxyphenylacetic acid for reducing the repellency of insecticides.
IT239603Y1 (en)	2001-03-05	SHOE STRUCTURE, PARTICULARLY FOR SKATES
NO965353D0 (en)	1996-12-13	3-Amino-2-oxo-1-piperidinedacetic acid derivatives as enzyme inhibitors
ID22205A (en)	1999-09-16	HOLIDAY SHOES PIT
ITRM960100V0 (en)	1996-05-22	ANTIQUE EFFECT FILM CRAQUELURES FOR CONTACT.
GB9610093D0 (en)	1996-07-17	(-)-(3R)-methyl-4-[4-[4-(4-pyridyl) piperazin-1-yl] phenoxy] butyric acid
KR970000223A (en)	1997-01-21	Cholesterol biosynthesis inhibitors
ZA964509B (en)	1996-12-02	(-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy}butyric acid
IT1275260B (en)	1997-07-31	NAIL PARTICULARLY FOR FOOTWEAR
ITBO970676A0 (en)	1997-11-18	BENDING METHOD, PARTICULARLY OF TABLETS.