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TNSN99096A1 - POLYMORPHIC FORMS OF A CRYSTALLINE PYRAZINE DERIVATIVE MONOCHLORHYDRATE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

POLYMORPHIC FORMS OF A CRYSTALLINE PYRAZINE DERIVATIVE MONOCHLORHYDRATE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
TNSN99096A1
TNSN99096A1 TNTNSN99096A TNSN99096A TNSN99096A1 TN SN99096 A1 TNSN99096 A1 TN SN99096A1 TN TNSN99096 A TNTNSN99096 A TN TNSN99096A TN SN99096 A TNSN99096 A TN SN99096A TN SN99096 A1 TNSN99096 A1 TN SN99096A1
Authority
TN
Tunisia
Prior art keywords
monochlorhydrate
preparation
pharmaceutical compositions
compositions containing
crystalline
Prior art date
Application number
TNTNSN99096A
Other languages
French (fr)
Inventor
John Meldrum Allen Douglas
Leonard Staigers Thomas
Randall Young Gregory
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN99096A1 publication Critical patent/TNSN99096A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION CONCERNE LES FORMES POLYMORPHES CRISTALLINES A ET B DU MONOCHLORHYDRATE DE (7S, 9aS)-7-[3-CYANOPHENOXY] METHYL-2-(5-FLUOROPYRIMIDINE-2 - YL) -2, 3, 4, 6, 7, 8, 9, 9 a-OCTAHYDRO-1H-PYRIDO [1,2-a] PYRAZINE. ELLE CONCERNE EGALEMENT UN PROCEDE POUR LEUR PREPARATION ET DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS POUR LE TRAITEMENT DE L'ANXIETE, DE LA DEPRESSION ET DES MALADIES PSYCHOTIQUES.THE INVENTION RELATES TO THE CRYSTALLINE POLYMORPH A AND B FORMS OF (7S, 9aS) -7- [3-CYANOPHENOXY] METHYL-2- (5-FLUOROPYRIMIDINE-2 - YL) MONOCHLORHYDRATE -2, 3, 4, 6, 7 , 8, 9, 9 a-OCTAHYDRO-1H-PYRIDO [1,2-a] PYRAZINE. IT ALSO CONCERNS A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. APPLICATION: USE OF THESE COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF ANXIETY, DEPRESSION AND PSYCHOTIC DISEASES.

TNTNSN99096A 1998-05-22 1999-05-19 POLYMORPHIC FORMS OF A CRYSTALLINE PYRAZINE DERIVATIVE MONOCHLORHYDRATE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM TNSN99096A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8641298P 1998-05-22 1998-05-22

Publications (1)

Publication Number Publication Date
TNSN99096A1 true TNSN99096A1 (en) 2005-11-10

Family

ID=22198401

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN99096A TNSN99096A1 (en) 1998-05-22 1999-05-19 POLYMORPHIC FORMS OF A CRYSTALLINE PYRAZINE DERIVATIVE MONOCHLORHYDRATE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (8)

Country Link
AP (1) AP9901544A0 (en)
AU (1) AU3529899A (en)
GT (1) GT199900060A (en)
MA (1) MA26632A1 (en)
PA (1) PA8470901A1 (en)
TN (1) TNSN99096A1 (en)
WO (1) WO1999061441A1 (en)
ZA (1) ZA993477B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL180899B1 (en) * 1994-09-30 2001-04-30 Pfizer Derivatives of 2,7-substituted octahydro-1h-pyrido[1,2-a]pyrasine

Also Published As

Publication number Publication date
PA8470901A1 (en) 2000-09-29
WO1999061441A1 (en) 1999-12-02
AU3529899A (en) 1999-12-13
GT199900060A (en) 2000-10-14
ZA993477B (en) 2000-11-21
AP9901544A0 (en) 1999-06-30
MA26632A1 (en) 2004-12-20

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