TN2014000358A1 - Topical compositions comprising fipronil and permethrin and methods of use - Google Patents
Topical compositions comprising fipronil and permethrin and methods of useInfo
- Publication number
- TN2014000358A1 TN2014000358A1 TNP2014000358A TN2014000358A TN2014000358A1 TN 2014000358 A1 TN2014000358 A1 TN 2014000358A1 TN P2014000358 A TNP2014000358 A TN P2014000358A TN 2014000358 A TN2014000358 A TN 2014000358A TN 2014000358 A1 TN2014000358 A1 TN 2014000358A1
- Authority
- TN
- Tunisia
- Prior art keywords
- glycol
- fipronil
- permethrin
- ester
- fatty acid
- Prior art date
Links
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 title abstract 4
- 239000005899 Fipronil Substances 0.000 title abstract 4
- 229940013764 fipronil Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960000490 permethrin Drugs 0.000 title abstract 3
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 9
- -1 glycol ester Chemical class 0.000 abstract 6
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 6
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract 3
- 229930195729 fatty acid Natural products 0.000 abstract 3
- 239000000194 fatty acid Substances 0.000 abstract 3
- 230000007935 neutral effect Effects 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 241001494115 Stomoxys calcitrans Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002940 repellent Effects 0.000 abstract 1
- 239000005871 repellent Substances 0.000 abstract 1
- 150000003457 sulfones Chemical class 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261602472P | 2012-02-23 | 2012-02-23 | |
| PCT/US2013/027312 WO2013126694A1 (fr) | 2012-02-23 | 2013-02-22 | Composition topique comprenant du fipronil et de la perméthrine et ses méthodes d'utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2014000358A1 true TN2014000358A1 (en) | 2015-12-21 |
Family
ID=47790542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2014000358A TN2014000358A1 (en) | 2012-02-23 | 2014-08-21 | Topical compositions comprising fipronil and permethrin and methods of use |
Country Status (44)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3626B1 (ar) * | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| US10717919B2 (en) | 2013-03-14 | 2020-07-21 | Flotek Chemistry, Llc | Methods and compositions for use in oil and/or gas wells |
| US10709135B2 (en) | 2013-07-29 | 2020-07-14 | Attillaps Holdings | Organophosphates for treating afflictions of the skin |
| US11446241B2 (en) | 2013-07-29 | 2022-09-20 | Attillaps Holdings Inc. | Treatment of ophthalmological conditions with acetylcholinesterase inhibitors |
| WO2015195928A1 (fr) | 2014-06-19 | 2015-12-23 | Attillaps Holdings | Inhibiteurs de l'acétylcholinestérase pour le traitement d'états dermatologiques |
| US9392792B1 (en) * | 2014-12-30 | 2016-07-19 | Virbac | Topical combination of fipronil, permethrin and pyriproxyfen |
| RU2732965C1 (ru) | 2015-07-10 | 2020-09-25 | Сева Санте Анималь | Комбинация неоникотиноидного и пиретроидного соединений для контроля распространения дирофиляриоза собак сердечной формы |
| EP3120846A1 (fr) * | 2015-07-24 | 2017-01-25 | Ceva Sante Animale | Compositions et leurs utilisations pour lutter contre les ectoparasites chez des mammifères non humains |
| CA3004810C (fr) | 2015-11-10 | 2020-08-11 | Neo-Innova Healthcare Limited | Composition insectifuge renfermant du p-methane-3.8-diol et methode d'utilisation |
| GB201520724D0 (en) * | 2015-11-24 | 2016-01-06 | Merial Inc | Veterinary formulations |
| AR104691A1 (es) | 2016-05-18 | 2017-08-09 | Labyes De Uruguay S A | Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros |
| AU2017261561B2 (en) * | 2017-11-16 | 2018-08-09 | Rotam Agrochem International Company Limited | A synergistic insecticidal composition comprising methomyl and fipronil |
| US10730901B2 (en) | 2018-07-27 | 2020-08-04 | Aperta Biosciences, Llc | Spinosyn formulations for treatment of demodex-induced ocular and facial conditions |
| SI3815677T1 (sl) | 2019-10-30 | 2023-12-29 | Krka, D.D., Novo Mesto | Stabilni veterinarski sestavek, ki obsega moksidektin in imidakloprid |
| RU2760526C1 (ru) * | 2020-12-22 | 2021-11-26 | Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" (ООО "НВЦ Агроветзащита") | Ветеринарная композиция для лечения и предотвращения паразитарных болезней у кошек и собак |
| CN117045592A (zh) * | 2023-09-11 | 2023-11-14 | 重庆汉佩生物科技有限公司 | 一种宠物耳部感染复方软膏及其制备方法 |
| EP4545067A1 (fr) | 2023-10-25 | 2025-04-30 | Infectopharm Arzneimittel und Consilium GmbH | Préparation de permethrin applicable par voie dermale à haute dose et chargé de drogue augmentée dans le compartiment cible pour un traitement amelioré d' infestation des éctoparasites |
Family Cites Families (185)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426333B1 (en) | 1996-09-19 | 2002-07-30 | Merial | Spot-on formulations for combating parasites |
| FR2753377B1 (fr) | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
| US2348930A (en) | 1942-05-06 | 1944-05-16 | Safety Car Heating & Lighting | Fluorescent lighting fixture |
| NL160809C (nl) | 1970-05-15 | 1979-12-17 | Duphar Int Res | Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen. |
| US3950360A (en) | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
| JPS4914624A (fr) | 1972-06-08 | 1974-02-08 | ||
| US3818047A (en) | 1972-08-07 | 1974-06-18 | C Henrick | Substituted pyrones |
| JPS5516402B2 (fr) | 1972-09-29 | 1980-05-01 | ||
| US4113968A (en) | 1974-10-03 | 1978-09-12 | Kuraray Co., Ltd. | Process for preparation of substituted cyclopropane carboxylic acids and esters thereof and intermediates of said acids and esters |
| SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| CH604517A5 (fr) | 1976-08-19 | 1978-09-15 | Ciba Geigy Ag | |
| US4134973A (en) | 1977-04-11 | 1979-01-16 | Merck & Co., Inc. | Carbohydrate derivatives of milbemycin and processes therefor |
| US4199569A (en) | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
| US4144352A (en) | 1977-12-19 | 1979-03-13 | Merck & Co., Inc. | Milbemycin compounds as anthelmintic agents |
| US4203976A (en) | 1978-08-02 | 1980-05-20 | Merck & Co., Inc. | Sugar derivatives of C-076 compounds |
| JPS57139012A (en) | 1981-02-23 | 1982-08-27 | Sankyo Co Ltd | Anthelmintic composition |
| US4427663A (en) | 1982-03-16 | 1984-01-24 | Merck & Co., Inc. | 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof |
| JPS59199673A (ja) | 1983-04-25 | 1984-11-12 | Sumitomo Chem Co Ltd | 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤 |
| DE3580444D1 (en) | 1984-10-18 | 1990-12-13 | Ciba Geigy Ag | Benzoylphenylharnstoffe. |
| ATE67493T1 (de) | 1985-02-04 | 1991-10-15 | Bayer Agrochem Kk | Heterocyclische verbindungen. |
| GB8713768D0 (en) | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
| GB8531485D0 (en) | 1985-12-20 | 1986-02-05 | May & Baker Ltd | Compositions of matter |
| US5232940A (en) | 1985-12-20 | 1993-08-03 | Hatton Leslie R | Derivatives of N-phenylpyrazoles |
| EP0237482A1 (fr) | 1986-03-06 | 1987-09-16 | Ciba-Geigy Ag | Dérivés de la C(29)-carbonyloxy-milbémycine pour la lutte contre les parasites d'espèces végétales ou animales |
| ES2019932B3 (es) | 1986-03-25 | 1991-07-16 | Sankyo Co | Compuestos macrolidos. |
| GB8613914D0 (en) | 1986-06-07 | 1986-07-09 | Coopers Animal Health | Liquid formulations |
| ES2039258T3 (es) | 1986-07-02 | 1993-09-16 | Ciba-Geigy Ag | Pesticidas. |
| US4855317A (en) | 1987-03-06 | 1989-08-08 | Ciba-Geigy Corporation | Insecticides and parasiticides |
| US4871719A (en) | 1987-03-24 | 1989-10-03 | Ciba-Geigy Corporation | Composition for controlling parasites in productive livestock |
| IT1214292B (it) | 1987-05-05 | 1990-01-10 | Garda Impianti Srl | Apparecchiatura per la misura e/o il controllo della posizione edella orientazione di punti o zone caratteristiche di strutture, in particolare di scocche di autoveicoli. |
| FR2616569B1 (fr) | 1987-06-12 | 1989-09-08 | Thomson Csf | Dispositif de visualisation a plusieurs ecrans plats escamotables |
| US4874749A (en) | 1987-07-31 | 1989-10-17 | Merck & Co., Inc. | 4"-Deoxy-4-N-methylamino avermectin Bla/Blb |
| GB8723347D0 (en) | 1987-10-05 | 1987-11-11 | Shell Int Research | Ectoparasiticidal pour-on formulation |
| DE3888936T2 (de) | 1987-11-03 | 1994-07-21 | Beecham Group Plc | Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. |
| SE8802173D0 (sv) | 1988-06-10 | 1988-06-10 | Astra Ab | Pyrimidine derivatives |
| GB8816915D0 (en) | 1988-07-15 | 1988-08-17 | May & Baker Ltd | New compositions of matter |
| OA09249A (fr) | 1988-12-19 | 1992-06-30 | Lilly Co Eli | Composés de macrolides. |
| NZ232422A (en) | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
| IE904606A1 (en) | 1989-12-21 | 1991-07-03 | Beecham Group Plc | Novel products |
| CA2036147A1 (fr) | 1990-06-29 | 1991-12-30 | Hiroki Tomioka | Derive de 1-pyridylimidazole ainsi que sa production et son utilisation |
| NZ247278A (en) | 1991-02-12 | 1995-03-28 | Ancare Distributors | Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier |
| US5236938A (en) | 1991-04-30 | 1993-08-17 | Rhone-Poulenc Inc. | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles |
| AU655014B2 (en) | 1991-04-30 | 1994-12-01 | Merial Limited | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles |
| WO1992022555A1 (fr) | 1991-06-17 | 1992-12-23 | Beecham Group Plc | Derives de paraherquamide, precurseur de ces derives, procedes de preparation, microorganisme utilise et utilisation de ces derives comme agents parasiticides |
| US5202242A (en) | 1991-11-08 | 1993-04-13 | Dowelanco | A83543 compounds and processes for production thereof |
| US5345377A (en) | 1992-10-30 | 1994-09-06 | Electric Power Research Institute, Inc. | Harmonic controller for an active power line conditioner |
| US5591606A (en) | 1992-11-06 | 1997-01-07 | Dowelanco | Process for the production of A83543 compounds with Saccharopolyspora spinosa |
| GB9300883D0 (en) | 1993-01-18 | 1993-03-10 | Pfizer Ltd | Antiparasitic agents |
| US5556873A (en) | 1993-02-24 | 1996-09-17 | Rhone-Poulenc Inc. | Pesticidal 1-aryl-5-(substituted alkyl (thio) amido)pyrazoles |
| BR9406587A (pt) | 1993-03-12 | 1996-01-02 | Dowelanco | Novos compostos a83543 e processo para a produção dos mesmos |
| US5321040A (en) | 1993-06-02 | 1994-06-14 | Rhone-Poulenc Inc. | Pesticidal 1-aryl-5-(substituted N-cinnamylideneimino) pyrazoles |
| US5399582A (en) | 1993-11-01 | 1995-03-21 | Merck & Co., Inc. | Antiparasitic agents |
| JP3715994B2 (ja) | 1993-12-21 | 2005-11-16 | 住友化学株式会社 | 害虫防除剤 |
| DE4343832A1 (de) | 1993-12-22 | 1995-06-29 | Bayer Ag | Substituierte 1-Arylpyrazole |
| US5750548A (en) | 1994-01-24 | 1998-05-12 | Novartis Corp. | 1- N-(halo-3-pyridylmethyl)!-N-methylamino-1-alklamino-2-nitroethylene derivatives for controlling fleas in domestic animals |
| CN1071089C (zh) | 1994-02-27 | 2001-09-19 | 罗纳-普朗克农业化学公司 | 拟除虫菊酯和n-苯基-吡唑的增效杀白蚁组合物 |
| AUPM969994A0 (en) | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
| IL116148A (en) | 1994-11-30 | 2001-03-19 | Rhone Poulenc Agrochimie | Complexible composition for insect control |
| DE4443888A1 (de) | 1994-12-09 | 1996-06-13 | Bayer Ag | Dermal applizierbare Formulierungen von Parasitiziden |
| US6221894B1 (en) | 1995-03-20 | 2001-04-24 | Merck & Co., Inc. | Nodulisporic acid derivatives |
| US5962499A (en) | 1995-03-20 | 1999-10-05 | Merck & Co., Inc. | Nodulisporic acid derivatives |
| US5629335A (en) | 1995-04-07 | 1997-05-13 | Rhone-Poulenc Inc. | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters |
| ZA964426B (en) | 1995-06-05 | 1997-03-06 | Rhone Poulenc Agrochimie | Pesticidal sulfur compounds |
| TW334436B (en) | 1995-07-21 | 1998-06-21 | Upjohn Co | Antiparasitic marcfortines and paraherquamides |
| US5595588A (en) | 1995-07-24 | 1997-01-21 | Alliedsignal Truck Brake Systems Co. | Air dryer cartridge mounting system |
| FR2739255B1 (fr) | 1995-09-29 | 1998-09-04 | Rhone Merieux | Composition antiparasitaire pour le traitement et la protection des animaux de compagnie |
| ATE236883T1 (de) | 1995-12-19 | 2003-04-15 | Bayer Cropscience Sa | Neue 1-aryl pyrazol derivate und ihre verwendung als schädlingsbekämpfungsmittel |
| US5814652A (en) | 1995-12-20 | 1998-09-29 | Rhone-Poulenc Inc. | Pesticidal 5-amino-4-ethylsulfinyl-1-arylpyrazoles |
| JPH10152476A (ja) | 1996-01-30 | 1998-06-09 | Takeda Chem Ind Ltd | 1−アリールピラゾール誘導体、その製造法および用途 |
| US5885607A (en) | 1996-03-29 | 1999-03-23 | Rhone Merieux | N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs |
| IE80657B1 (en) | 1996-03-29 | 1998-11-04 | Merial Sas | Insecticidal combination to control mammal fleas in particular fleas on cats and dogs |
| US6413542B1 (en) | 1996-03-29 | 2002-07-02 | Merial | Direct pour-on antiparasitic skin solution and methods for treating, preventing and controlling myasis |
| US6010710A (en) | 1996-03-29 | 2000-01-04 | Merial | Direct pour-on skin solution for antiparasitic use in cattle and sheep |
| FR2752525B1 (fr) * | 1996-08-20 | 2000-05-05 | Rhone Merieux | Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede |
| US6001981A (en) | 1996-06-13 | 1999-12-14 | Dow Agrosciences Llc | Synthetic modification of Spinosyn compounds |
| ES2215231T3 (es) | 1996-07-25 | 2004-10-01 | Pfizer Inc. | Pirazoles antiparasitarios. |
| US6998131B2 (en) | 1996-09-19 | 2006-02-14 | Merial Limited | Spot-on formulations for combating parasites |
| EP0839809A1 (fr) | 1996-11-01 | 1998-05-06 | Rhone-Poulenc Agrochimie | Dérivés pesticides 1-arylpyrazole-5-sulfinilimine |
| GB9625045D0 (en) | 1996-11-30 | 1997-01-22 | Pfizer Ltd | Parasiticidal compounds |
| US6069157A (en) | 1997-11-25 | 2000-05-30 | Pfizer Inc. | Parasiticidal compounds |
| DE19650197A1 (de) | 1996-12-04 | 1998-06-10 | Bayer Ag | 3-Thiocarbamoylpyrazol-Derivate |
| TW524667B (en) | 1996-12-05 | 2003-03-21 | Pfizer | Parasiticidal pyrazoles |
| BR9714181A (pt) | 1996-12-24 | 2000-02-29 | Rhone Poulenc Agrochimie | Processo para controlar insetos por meio de aplicação de um ingrediente inseticidamente ativo, composições pesticida e afidicida, composto, e, processo para preparar o mesmo. |
| SK284351B6 (sk) | 1996-12-24 | 2005-02-04 | Rhone-Poulenc Agro | 1-Arylpyrazoly a ich soli, pesticídne prostriedky obsahujúce tieto zlúčeniny ako účinné látky, spôsob prípravy 1-arylpyrazolov a spôsob regulácie škodcov |
| US6350771B1 (en) | 1996-12-24 | 2002-02-26 | Rhone-Poulenc, Inc. | Pesticidal 1-arylpyrazoles |
| ZA981934B (en) | 1997-03-10 | 1999-09-06 | Rhone Poulenc Agrochimie | Pesticidal 1-aryl-3-iminopyrazoles. |
| ZA981776B (en) | 1997-03-10 | 1998-09-03 | Rhone Poulenc Agrochimie | Pesticidal 1-arylpyrazoles |
| AU6826898A (en) | 1997-03-11 | 1998-09-29 | Rhone-Poulenc Agro | Pesticidal combination |
| AU6523398A (en) | 1997-04-07 | 1998-10-30 | Mitsubishi Corporation | Pyrazole derivatives, process for preparing the same, intermediates, and pest control agent containing the same as active ingredient |
| US6207647B1 (en) | 1997-07-18 | 2001-03-27 | Smithkline Beecham Corporation | RatA |
| JP3489401B2 (ja) | 1997-07-31 | 2004-01-19 | 住友化学工業株式会社 | 殺虫剤組成物 |
| EP0911329A1 (fr) | 1997-10-07 | 1999-04-28 | Rhone-Poulenc Agro | Dérivés 3-substitués d'arylpyrazole |
| GB9801851D0 (en) | 1998-01-29 | 1998-03-25 | Pfizer Ltd | Parasiticidal agents |
| EP1063992B1 (fr) | 1998-03-19 | 2005-05-11 | Merck & Co., Inc. | Sulfurpenta fluorophenyl pyrazoles utiles dans la lutte contre les infestations par les ectoparasites |
| CN1131863C (zh) | 1998-06-02 | 2003-12-24 | 住化武田农药株式会社 | 噁二唑啉衍生物及其作为杀虫剂的用途 |
| DE19824487A1 (de) | 1998-06-02 | 1999-12-09 | Bayer Ag | Substituierte 3-Thiocarbamoylpyrazole |
| US6090751A (en) | 1998-06-10 | 2000-07-18 | Rhone-Poulenc Agro | Emulsifiable concentrate comprising an insecticidal 1-arylpyrazole |
| US6174540B1 (en) | 1998-09-14 | 2001-01-16 | Merck & Co., Inc. | Long acting injectable formulations containing hydrogenated caster oil |
| DE19853560A1 (de) | 1998-11-20 | 2000-05-25 | Bayer Ag | Verfahren zur Herstellung von 5-Amino-3-(thio)carbamoylpyrazolen |
| DE69915878T2 (de) | 1998-12-18 | 2005-03-03 | Dow Global Technologies, Inc., Midland | Verfahren zur herstellung von 2,3-dihalogenpropanolen |
| ATE271314T1 (de) | 1998-12-22 | 2004-08-15 | Bayer Cropscience Sa | Verfahren zur schädlingsbekämpfung |
| AU2878400A (en) * | 1999-02-11 | 2000-08-29 | Salk Institute For Biological Studies, The | Integration of transplanted neural progenitor cells into neural tissue of immature and mature dystrophic recipients |
| DE19913534A1 (de) | 1999-03-25 | 2000-10-05 | Bayer Ag | Avermectinderivate |
| DE19954394A1 (de) | 1999-11-12 | 2001-05-17 | Bayer Ag | Verwendung von Polysiloxanen mit quartären Aminogruppen als Formulierungshilfe und Mittel enthalten dieselben |
| DE10004084A1 (de) | 2000-01-31 | 2001-08-02 | Bayer Ag | Substituierte Imid-Derivate |
| FR2805971B1 (fr) | 2000-03-08 | 2004-01-30 | Aventis Cropscience Sa | Procedes de traitement et/ou de protection des cultures contre les arthropodes et compositions utiles pour de tels procedes |
| PE20011289A1 (es) | 2000-04-07 | 2001-12-21 | Upjohn Co | Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles |
| US6399786B1 (en) | 2000-07-14 | 2002-06-04 | Merck & Co., Inc. | Nonacyclic nodulisporic acid derivatives |
| US20020103233A1 (en) | 2000-11-30 | 2002-08-01 | Arther Robert G. | Compositions for enhanced acaricidal activity |
| DE10117676A1 (de) * | 2001-04-09 | 2002-10-10 | Bayer Ag | Dermal applizierbare flüssige Formulierungen zur Bekämpfung von parasitierenden Insekten an Tieren |
| AR036872A1 (es) | 2001-08-13 | 2004-10-13 | Du Pont | Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados |
| CA2464403A1 (fr) | 2001-10-25 | 2003-05-01 | Sankyo Lifetech Company, Limited | Composition anthelmintique |
| FR2834288B1 (fr) | 2001-12-28 | 2011-12-16 | Virbac Sa | Procede de preparation de nouveaux derives n-substitues de 5-amino-phenylpyrazole, nouveaux derives n-substitues de 5-amino-phenylpyrazole et leur utilisation comme agents parasiticides et/ou insecticides |
| TW200409760A (en) | 2002-09-11 | 2004-06-16 | Novartis Ag | Organic compounds |
| US20050245582A1 (en) * | 2002-09-12 | 2005-11-03 | The Hartz Mountain Corporation | High concentration topical insecticides containing pyrethroids |
| GB2396557A (en) | 2002-11-25 | 2004-06-30 | John Strauss | Protecting animals against ectoparasite infestations |
| US7262214B2 (en) * | 2003-02-26 | 2007-08-28 | Merial Limited | 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases |
| DE10320505A1 (de) | 2003-05-08 | 2004-11-25 | Bayer Healthcare Ag | Mittel zum Bekämpfen von Parasiten an Tieren |
| DE102004021564A1 (de) | 2003-11-14 | 2005-07-07 | Bayer Cropscience Ag | Wirkstoffkombinationen mit insektiziden Eigenschaften |
| US7531186B2 (en) | 2003-12-17 | 2009-05-12 | Merial Limited | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz |
| US7514464B2 (en) | 2003-12-18 | 2009-04-07 | Pfizer Limited | Substituted arylpyrazoles |
| ZA200607637B (en) | 2004-03-05 | 2008-05-28 | Nissan Chemical Ind Ltd | Isoxazoline-substituted benzamide compound and noxious organism control agent |
| EP1574502A1 (fr) | 2004-03-08 | 2005-09-14 | Novartis AG | Utilisation de composés pyrimidine pour la préparation d'agents parasiticides |
| AU2005223483B2 (en) | 2004-03-18 | 2009-04-23 | Zoetis Llc | N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides |
| US20100261396A1 (en) * | 2004-07-02 | 2010-10-14 | Dixon Timothy R | Insecticidally treated fabric having improved wash durability and insecticidal efficacy and method for its production |
| US20060025728A1 (en) | 2004-07-30 | 2006-02-02 | Leiboff Arnold R | Device and method for colonic lavage |
| WO2007026965A1 (fr) | 2005-09-02 | 2007-03-08 | Nissan Chemical Industries, Ltd. | Composé de benzamide à substitution isoxazoline et agent de lutte contre les organismes nuisibles |
| US20090143410A1 (en) | 2005-12-14 | 2009-06-04 | Kanu Maganbhai Patel | Isoxazolines for Controlling Invertebrate Pests |
| TW200803740A (en) | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| ATE466846T1 (de) | 2006-03-10 | 2010-05-15 | Nissan Chemical Ind Ltd | Substituierte isoxazolin-verbindung und schädlingsbekämpfungsmittel |
| KR20090005201A (ko) | 2006-04-20 | 2009-01-12 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 무척추 해충 방제용 피라졸린 |
| AU2007257076B2 (en) | 2006-04-28 | 2012-04-12 | Ceva Animal Health, Llc | High concentration topical insecticides containing pyrethroids |
| WO2007125984A1 (fr) | 2006-04-28 | 2007-11-08 | Nihon Nohyaku Co., Ltd. | Derive isoxazoline, agent insecticide et utilisation de l'agent insecticide |
| KR101437704B1 (ko) | 2006-07-05 | 2014-09-04 | 아벤티스 애그리컬쳐 | 1-아릴-5-알킬 피라졸 유도체 화합물, 이의 제조 방법 및 이의 사용 방법 |
| JP2008044880A (ja) | 2006-08-15 | 2008-02-28 | Bayer Cropscience Ag | 殺虫性イソオキサゾリン類 |
| DE102006061537A1 (de) | 2006-12-27 | 2008-07-03 | Bayer Healthcare Ag | Mittel zur Bekämpfung von Parasiten an Tieren |
| DE102006061538A1 (de) | 2006-12-27 | 2008-07-03 | Bayer Healthcare Ag | Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren |
| RU2340181C1 (ru) * | 2007-03-06 | 2008-12-10 | Александр Анатольевич Хахалин | Инсектоакарицидное средство "инсектал-плюс" |
| EP2151437A4 (fr) | 2007-03-07 | 2012-05-02 | Nissan Chemical Ind Ltd | Composé de benzamide substitué par isoxazoline et agent de contrôle des nuisibles |
| US8114814B2 (en) | 2007-03-16 | 2012-02-14 | Kumiai Chemical Industry Co., Ltd. | Herbicide composition |
| JP5256753B2 (ja) | 2007-03-29 | 2013-08-07 | 住友化学株式会社 | イソオキサゾリン化合物とその有害生物防除用途 |
| CA2683180A1 (fr) | 2007-04-10 | 2008-10-16 | Bayer Cropscience Ag | Derives d'arzlisoxayoline insecticides |
| SI2155699T1 (sl) | 2007-05-15 | 2015-12-31 | Merial, Inc. | Ariloazol-2-il cianoetilamino spojine, postopek njihove izdelave in postopek njihove uporabe |
| CA2684671A1 (fr) | 2007-06-13 | 2008-12-18 | E.I. Du Pont De Nemours And Company | Insecticides a l'isoxazoline |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| WO2009001942A1 (fr) | 2007-06-27 | 2008-12-31 | Nissan Chemical Industries, Ltd. | Procédé de production du composé 3-hydroxypropane-1-one, procédé de production du composé 2-propène-1-one et procédé de production d'un composé d'isoxazoline |
| EP2172448A4 (fr) | 2007-06-29 | 2012-01-11 | Nissan Chemical Ind Ltd | Composé isoxazoline ou énone oxime substitué, et agent de lutte contre les nuisibles |
| CN101686962B (zh) | 2007-06-29 | 2012-05-23 | 辉瑞大药厂 | 驱虫药联合用药 |
| TWI556741B (zh) | 2007-08-17 | 2016-11-11 | 英特威特國際股份有限公司 | 異唑啉組成物及其作為抗寄生蟲藥上的應用 |
| JP5365806B2 (ja) | 2007-09-10 | 2013-12-11 | 日産化学工業株式会社 | 置換イソキサゾリン化合物及び有害生物防除剤 |
| ES2399572T3 (es) | 2007-10-03 | 2013-04-02 | E. I. Du Pont De Nemours And Company | Compuestos de naftaleno isoxazolina para el control de plagas de invertebrados |
| CA2708170C (fr) * | 2007-12-20 | 2016-06-14 | Syngenta Participations Ag | Lutte contre les fourmis |
| JP2011527307A (ja) | 2008-07-09 | 2011-10-27 | ビーエーエスエフ ソシエタス・ヨーロピア | イソオキサゾリン化合物iを含む殺有害生物活性混合物 |
| WO2010003877A1 (fr) | 2008-07-09 | 2010-01-14 | Basf Se | Mélanges pesticides comprenant des composés de type isoxazoline ii |
| ES2582575T3 (es) | 2008-07-09 | 2016-09-13 | Nissan Chemical Industries, Ltd. | Procedimiento para la producción de compuesto de amida del ácido benzoico sustituido con isoxazolina |
| EP2331535B1 (fr) | 2008-09-04 | 2015-07-22 | Syngenta Participations AG | Composés insecticides |
| NZ592382A (en) | 2008-10-21 | 2013-03-28 | Merial Ltd | Thioamide compounds, method of making and method of using thereof |
| ES2729854T3 (es) | 2008-11-14 | 2019-11-06 | Merial Inc | Compuestos de ariloazol-2-ilcianoetilamino parasiticidas enriquecidos enantioméricamente |
| ES2442342T3 (es) | 2008-12-18 | 2014-02-11 | Novartis Ag | Derivados de las isoxazolinas y su uso como pesticida |
| HUE015568T4 (en) | 2008-12-19 | 2017-10-30 | Elanco Tiergesundheit Ag | Isoxazoline derivatives and their use as pesticides |
| EP2411384B1 (fr) | 2009-03-26 | 2013-01-30 | Syngenta Participations AG | Composés insecticides |
| EP2414353A1 (fr) | 2009-04-01 | 2012-02-08 | Basf Se | Composés d'isoxazoline pour lutter contre les ravageurs invertébrés |
| US8614244B2 (en) | 2009-09-22 | 2013-12-24 | Segeant's Pet Care Products, Inc. | Spot-on pesticide composition |
| TWI487486B (zh) | 2009-12-01 | 2015-06-11 | Syngenta Participations Ag | 以異唑啉衍生物為主之殺蟲化合物 |
| PT2513104E (pt) | 2009-12-17 | 2016-06-03 | Merial Inc | Compostos de di-hidroazole antiparasitários e composições que compreendem os mesmos |
| BR112012017540A2 (pt) * | 2010-01-29 | 2016-08-02 | Pfizer | formulações antiparasitárias tópicas |
| US8999889B2 (en) | 2010-02-01 | 2015-04-07 | Basf Se | Substituted ketonic isoxazoline compounds and derivatives for combating animal pests |
| EP2538788A1 (fr) | 2010-02-25 | 2013-01-02 | Syngenta Participations AG | Mélanges pesticides comprenant des dérivés d'isoxazoline et un agent biologique insecticide ou nématicide |
| PH12012501625A1 (en) | 2010-02-25 | 2012-10-22 | Syngenta Participations Ag | Process for the preparation of isoxazoline derivatives |
| US20120324604A1 (en) | 2010-02-25 | 2012-12-20 | Syngenta Crop Protection Llc | Pesticidal mixtures containing isoxazoline derivatives and a fungicide |
| CA2794428A1 (fr) | 2010-04-08 | 2011-10-13 | Pfizer Inc. | Derives de 3,5-diphenyl-isoxazoline substitues comme insecticides et acaricides |
| CN101804048B (zh) * | 2010-04-16 | 2014-06-11 | 上海汉维生物医药科技有限公司 | 用于动物的抗寄生物组合物 |
| WO2011154434A2 (fr) | 2010-06-09 | 2011-12-15 | Syngenta Participations Ag | Mélanges pesticides comprenant des dérivés d' isoxazoline |
| WO2011154433A2 (fr) | 2010-06-09 | 2011-12-15 | Syngenta Participations Ag | Mélanges pesticides comprenant des dérivés d' isoxazoline |
| UY33403A (es) | 2010-06-17 | 2011-12-30 | Novartis Ag | Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales |
| CA2807005C (fr) | 2010-08-05 | 2015-04-07 | Ah Usa 42 Llc | Derives d'isoxazoline en tant qu'agents antiparasitaires |
| ES2793481T3 (es) | 2010-09-24 | 2020-11-16 | Zoetis Services Llc | Oximas de isoxazolina como agentes antiparasitarios |
| WO2012086462A1 (fr) | 2010-12-20 | 2012-06-28 | 日本曹達株式会社 | Composé isoxazoline et agent de lutte contre les parasites |
| KR20130130761A (ko) | 2010-12-27 | 2013-12-02 | 인터벳 인터내셔널 비.브이. | 국소 적용 이속사졸린 제제 |
| PT2658541T (pt) | 2010-12-27 | 2022-03-11 | Intervet Int Bv | Formulação de isoxazolina localizada tópica compreendendo glicofurol |
| MX2013009211A (es) | 2011-02-10 | 2013-08-29 | Novartis Ag | Derivados de isoxazolina para controlar plagas de invertebrados. |
| ME02412B (fr) | 2011-03-10 | 2016-09-20 | Zoetis Services Llc | Dérivés d'isoxazolines spirocycliques à titre d'agents antiparasitaires |
| CA2829149A1 (fr) | 2011-03-10 | 2012-09-13 | Novartis Ag | Derives d'isoxazole |
| JO3626B1 (ar) * | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
-
2013
- 2013-02-21 JO JOP/2013/0055A patent/JO3626B1/ar active
- 2013-02-22 HU HUE13707523A patent/HUE047727T2/hu unknown
- 2013-02-22 GE GEAP201313575A patent/GEP201606580B/en unknown
- 2013-02-22 KR KR1020207003884A patent/KR102152569B1/ko active Active
- 2013-02-22 PE PE2014001294A patent/PE20141998A1/es active IP Right Grant
- 2013-02-22 MD MDA20140102A patent/MD4525C1/ro active IP Right Grant
- 2013-02-22 MX MX2014010106A patent/MX369418B/es active IP Right Grant
- 2013-02-22 PH PH1/2014/501905A patent/PH12014501905B1/en unknown
- 2013-02-22 KR KR1020197012454A patent/KR102078516B1/ko active Active
- 2013-02-22 EA EA201891058A patent/EA038168B1/ru unknown
- 2013-02-22 MY MYPI2018000104A patent/MY197215A/en unknown
- 2013-02-22 HR HRP20200513TT patent/HRP20200513T1/hr unknown
- 2013-02-22 SG SG11201405026QA patent/SG11201405026QA/en unknown
- 2013-02-22 MY MYPI2014002427A patent/MY175189A/en unknown
- 2013-02-22 AU AU2013222249A patent/AU2013222249B2/en active Active
- 2013-02-22 NZ NZ629045A patent/NZ629045A/en unknown
- 2013-02-22 ME MEP-2020-70A patent/ME03768B/fr unknown
- 2013-02-22 EP EP13707523.0A patent/EP2816898B1/fr active Active
- 2013-02-22 AR ARP130100538A patent/AR090122A1/es active IP Right Grant
- 2013-02-22 SM SM20200075T patent/SMT202000075T1/it unknown
- 2013-02-22 UA UAA201410391A patent/UA113756C2/uk unknown
- 2013-02-22 WO PCT/US2013/027312 patent/WO2013126694A1/fr not_active Ceased
- 2013-02-22 EP EP19206350.1A patent/EP3659439A1/fr active Pending
- 2013-02-22 EA EA201400942A patent/EA031714B1/ru unknown
- 2013-02-22 DK DK13707523.0T patent/DK2816898T3/da active
- 2013-02-22 JP JP2014558863A patent/JP6183861B2/ja active Active
- 2013-02-22 ES ES13707523T patent/ES2801048T3/es active Active
- 2013-02-22 MX MX2018006860A patent/MX382884B/es unknown
- 2013-02-22 BR BR112014020647-3A patent/BR112014020647B1/pt active IP Right Grant
- 2013-02-22 UY UY0001034636A patent/UY34636A/es active IP Right Grant
- 2013-02-22 PT PT137075230T patent/PT2816898T/pt unknown
- 2013-02-22 MX MX2019013094A patent/MX382531B/es unknown
- 2013-02-22 KR KR1020147026655A patent/KR101977591B1/ko active Active
- 2013-02-22 PL PL13707523T patent/PL2816898T3/pl unknown
- 2013-02-22 AP AP2014007890A patent/AP2014007890A0/xx unknown
- 2013-02-22 CN CN201380017270.7A patent/CN104202985B/zh active Active
- 2013-02-22 CA CA2865117A patent/CA2865117C/fr active Active
- 2013-02-22 LT LTEP13707523.0T patent/LT2816898T/lt unknown
- 2013-02-22 RS RS20200380A patent/RS60109B1/sr unknown
- 2013-02-22 US US13/774,159 patent/US9457088B2/en active Active
- 2013-02-22 SI SI201331666T patent/SI2816898T1/sl unknown
- 2013-02-23 TW TW102106448A patent/TWI578908B/zh active
-
2014
- 2014-08-20 CR CR20140391A patent/CR20140391A/es unknown
- 2014-08-21 IL IL234230A patent/IL234230A/en active IP Right Grant
- 2014-08-21 TN TNP2014000358A patent/TN2014000358A1/fr unknown
- 2014-08-21 CL CL2014002228A patent/CL2014002228A1/es unknown
- 2014-08-22 ZA ZA2014/06192A patent/ZA201406192B/en unknown
- 2014-09-10 MA MA37348A patent/MA37348B1/fr unknown
- 2014-09-23 EC ECIEPI201419920A patent/ECSP14019920A/es unknown
- 2014-09-23 CO CO14210001A patent/CO7141409A2/es unknown
-
2016
- 2016-06-29 AU AU2016204502A patent/AU2016204502B2/en active Active
- 2016-08-26 US US15/248,327 patent/US9949953B2/en active Active
-
2017
- 2017-07-19 JP JP2017139772A patent/JP6445102B2/ja active Active
-
2018
- 2018-03-28 US US15/937,878 patent/US10646473B2/en active Active
- 2018-04-17 AU AU2018202648A patent/AU2018202648B2/en active Active
-
2020
- 2020-03-10 CY CY20201100210T patent/CY1122838T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TN2014000358A1 (en) | Topical compositions comprising fipronil and permethrin and methods of use | |
| BR112016002915A2 (pt) | formulação agroquímica pulverizável, formulação concentrada, uso de um éster graxo de um poliol c3 a c8, ou oligômero do mesmo, e, métodos para reduzir o desvio de pulverização e para tratamento de vegetação para controlar pestes e/ou fornecer nutrientes | |
| KR101295228B1 (ko) | 축사 및 양계 소독용 살충제 조성물 및 이의 제조방법 | |
| AR093742A1 (es) | Composiciones sinergicas que comprenden etefona y saflufenacilo o ciclanilida y saflufenacilo | |
| IN2014CN04034A (fr) | ||
| CO6251200A2 (es) | Metodo para modular la tasa de liberacion de ingredientes activos microencapsulados usado paa la proteccion de cultivos | |
| WO2016116403A8 (fr) | Solutions de polyuréthane-urée pour des compositions contenant des substances actives ou des parfums | |
| DE602004021855D1 (de) | Formulierung einer synergistischen insektiziden zusammensetzung als cyclodextrin-komplex | |
| MX358473B (es) | Formulaciones de giberelina con baja cantidad de productos quimicos organicos volatiles. | |
| BR112017017643A2 (pt) | formulação farmacêutica tópica | |
| EA200702593A1 (ru) | Высококонцентрированные композиции, применимые для борьбы с экто- и эндопаразитами | |
| WO2014169003A3 (fr) | Composition multifonctionnelle pour des formulations cosmétiques | |
| AR077584A1 (es) | Formulaciones herbicidas estabilizadas y metodos de uso | |
| UY37867A (es) | Formulación de uso tópico para el control y la prevención de parásitos en animales | |
| NZ703176A (en) | Stable pexiganan formulation | |
| AR080054A1 (es) | Formulaciones antiparasitarias topicas | |
| CO2024005848A2 (es) | Formulación que comprende un activo de función ácida, un activo de función éster y un activo salino y/o químicamente lábil, su uso y método de producción | |
| MX2022004368A (es) | Formulacion de mezclas insecticidas que comprenden disolventes de eter de glicol. | |
| TH154049A (th) | องค์ประกอบสำหรับใช้เฉพาะที่ซึ่งประกอบรวมด้วยไฟโพรนิลและเพอร์เมธรินและวิธีใช้ | |
| PH12022550873A1 (en) | Formulation of insecticides comprising glycol ether solvents | |
| TN2017000462A1 (en) | Ec formulations comprising organophosphate insecticides | |
| JP6164942B2 (ja) | 皮膚外用剤 | |
| TH160193A (th) | องค์ประกอบยาต้านจุลชีพที่ได้รับการปรับปรุง | |
| TH10559A3 (th) | ผลิตภัณฑ์ไมโครอิมัลชันเพื่อบรรเทาปวด และอักเสบที่มีส่วนผสมของน้ำมันไพลและสารสกัดพริก | |
| TH10559C3 (th) | ผลิตภัณฑ์ไมโครอิมัลชันเพื่อบรรเทาปวด และอักเสบที่มีส่วนผสมของน้ำมันไพลและสารสกัดพริก |