TN2010000342A1 - Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy - Google Patents

Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy

Info

Publication number: TN2010000342A1
Authority: TN; Tunisia
Prior art keywords: muscular dystrophy; treatment; immunosuppressive cyclosporin; cyclosporin; immunosuppressive
Prior art date: 2008-02-08

Application number

TNP2010000342A

Other languages

English (en)

Inventor

Jeffery D Molkentin

Original Assignee

Debiopharm Sa Ch

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-02-08

Filing date

2010-07-21

Publication date

2011-12-29

2010-07-21 Application filed by Debiopharm Sa Ch filed Critical Debiopharm Sa Ch

2011-12-29 Publication of TN2010000342A1 publication Critical patent/TN2010000342A1/fr

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
229930105110 Cyclosporin A Natural products 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
201000006938 muscular dystrophy Diseases 0.000 title 1
201000009342 Limb-girdle muscular dystrophy Diseases 0.000 abstract 1
230000007850 degeneration Effects 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
230000003387 muscular Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Physical Education & Sports Medicine (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

TNP2010000342A 2008-02-08 2010-07-21 Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy TN2010000342A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/IB2008/000292 WO2009098533A1 (fr)	2008-02-08	2008-02-08	Cyclosporine non immunosuppressive pour le traitement de la dystrophie musculaire
PCT/IB2009/000204 WO2009098577A2 (fr)	2008-02-08	2009-02-05	Cyclosporine non immunosuppressive pour le traitement de la dystrophie musculaire

Publications (1)

Publication Number	Publication Date
TN2010000342A1 true TN2010000342A1 (en)	2011-12-29

Family

ID=39951648

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2010000342A TN2010000342A1 (en)	2008-02-08	2010-07-21	Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy

Country Status (25)

Country	Link
US (1)	US20100323972A1 (fr)
EP (1)	EP2249860B8 (fr)
JP (1)	JP5536673B2 (fr)
KR (1)	KR101633772B1 (fr)
CN (1)	CN101939021B (fr)
AU (1)	AU2009211129B2 (fr)
BR (1)	BRPI0908376A8 (fr)
CA (1)	CA2713416C (fr)
CY (1)	CY1120000T1 (fr)
DK (1)	DK2249860T3 (fr)
EA (1)	EA021701B1 (fr)
ES (1)	ES2558710T3 (fr)
HR (1)	HRP20151413T1 (fr)
HU (1)	HUE026567T2 (fr)
IL (1)	IL207477A (fr)
MA (1)	MA32129B1 (fr)
MX (1)	MX2010008533A (fr)
PL (1)	PL2249860T3 (fr)
PT (1)	PT2249860E (fr)
RS (1)	RS54494B1 (fr)
SI (1)	SI2249860T1 (fr)
TN (1)	TN2010000342A1 (fr)
UA (1)	UA101177C2 (fr)
WO (2)	WO2009098533A1 (fr)
ZA (1)	ZA201005483B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3128192B2 (ja)	1995-12-06	2001-01-29	信越化学工業株式会社	アリルトリアルコキシシラン化合物の製造方法
MX2009007045A (es) *	2007-01-04	2009-10-07	Debiopharm Sa	Ciclosporina no inmunosupresora para el tratamiento de distrofia muscular congenita de ullrich.
WO2011141891A1 (fr)	2010-05-12	2011-11-17	Debio Recherche Pharmaceutique S.A.	Utilisation de composés cycloundécadepsipeptides
US20150133369A1 (en)	2012-05-07	2015-05-14	Steven Kovacs	Pharmacokinetic modulation with alisporivir
AR090964A1 (es)	2012-05-09	2014-12-17	Novartis Ag	Proceso para la elaboracion de undecapeptidos ciclicos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9911724A (pt) *	1998-07-01	2001-03-20	Debiopharm Sa	Ciclosporina que tem um perfil de atividade melhorado
CN1507451A (zh) *	2001-04-20	2004-06-23	�±Ȱ·�ķ�ɷ��޹�˾	可用作前体药物的修饰环孢菌素及其应用
SG139750A1 (en) *	2004-10-01	2008-02-29	Debiopharm Sa Ch	Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3- [etval]4-cyclosporin
ES2387682T3 (es) *	2005-01-10	2012-09-28	Debiopharm S.A.	Utilización de un undecapéptido cíclico para la preparación de un medicamento administrable durante situaciones isquémicas miocárdicas
MX2009007045A (es) *	2007-01-04	2009-10-07	Debiopharm Sa	Ciclosporina no inmunosupresora para el tratamiento de distrofia muscular congenita de ullrich.

2008
- 2008-02-08 WO PCT/IB2008/000292 patent/WO2009098533A1/fr not_active Ceased
2009
- 2009-02-05 BR BRPI0908376A patent/BRPI0908376A8/pt not_active Application Discontinuation
- 2009-02-05 KR KR1020107019296A patent/KR101633772B1/ko not_active Expired - Fee Related
- 2009-02-05 JP JP2010545572A patent/JP5536673B2/ja not_active Expired - Fee Related
- 2009-02-05 ES ES09707226.8T patent/ES2558710T3/es active Active
- 2009-02-05 PT PT97072268T patent/PT2249860E/pt unknown
- 2009-02-05 SI SI200931348T patent/SI2249860T1/sl unknown
- 2009-02-05 CN CN2009801043707A patent/CN101939021B/zh not_active Expired - Fee Related
- 2009-02-05 PL PL09707226T patent/PL2249860T3/pl unknown
- 2009-02-05 WO PCT/IB2009/000204 patent/WO2009098577A2/fr not_active Ceased
- 2009-02-05 UA UAA201010796A patent/UA101177C2/ru unknown
- 2009-02-05 AU AU2009211129A patent/AU2009211129B2/en not_active Ceased
- 2009-02-05 DK DK09707226.8T patent/DK2249860T3/en active
- 2009-02-05 RS RS20160008A patent/RS54494B1/sr unknown
- 2009-02-05 EP EP09707226.8A patent/EP2249860B8/fr active Active
- 2009-02-05 US US12/866,844 patent/US20100323972A1/en not_active Abandoned
- 2009-02-05 CA CA2713416A patent/CA2713416C/fr not_active Expired - Fee Related
- 2009-02-05 MX MX2010008533A patent/MX2010008533A/es active IP Right Grant
- 2009-02-05 EA EA201070945A patent/EA021701B1/ru not_active IP Right Cessation
- 2009-02-05 HU HUE09707226A patent/HUE026567T2/hu unknown
- 2009-02-05 HR HRP20151413TT patent/HRP20151413T1/hr unknown
2010
- 2010-07-21 TN TNP2010000342A patent/TN2010000342A1/fr unknown
- 2010-07-30 ZA ZA2010/05483A patent/ZA201005483B/en unknown
- 2010-08-08 IL IL207477A patent/IL207477A/en not_active IP Right Cessation
- 2010-09-01 MA MA33133A patent/MA32129B1/fr unknown
2016
- 2016-01-11 CY CY20161100018T patent/CY1120000T1/el unknown

Also Published As

Publication number	Publication date
AU2009211129B2 (en)	2013-10-31
US20100323972A1 (en)	2010-12-23
DK2249860T3 (en)	2016-01-18
CA2713416C (fr)	2017-05-23
EA021701B1 (ru)	2015-08-31
BRPI0908376A2 (pt)	2015-08-11
JP2011511057A (ja)	2011-04-07
IL207477A0 (en)	2010-12-30
AU2009211129A1 (en)	2009-08-13
MA32129B1 (fr)	2011-03-01
SI2249860T1 (sl)	2016-02-29
KR20100114914A (ko)	2010-10-26
EA201070945A1 (ru)	2011-02-28
KR101633772B1 (ko)	2016-06-27
JP5536673B2 (ja)	2014-07-02
EP2249860B1 (fr)	2015-10-14
CN101939021A (zh)	2011-01-05
CN101939021B (zh)	2013-01-30
WO2009098533A1 (fr)	2009-08-13
MX2010008533A (es)	2010-08-30
RS54494B1 (sr)	2016-06-30
BRPI0908376A8 (pt)	2016-07-12
EP2249860A2 (fr)	2010-11-17
HRP20151413T1 (hr)	2016-02-12
ZA201005483B (en)	2012-02-29
CA2713416A1 (fr)	2009-08-13
CY1120000T1 (el)	2018-12-12
HUE026567T2 (hu)	2016-06-28
EP2249860B8 (fr)	2015-11-18
HK1148665A1 (en)	2011-09-16
WO2009098577A2 (fr)	2009-08-13
ES2558710T3 (es)	2016-02-08
UA101177C2 (ru)	2013-03-11
PL2249860T3 (pl)	2016-04-29
WO2009098577A3 (fr)	2010-05-20
IL207477A (en)	2017-04-30
PT2249860E (pt)	2016-02-05

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