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TN2009000374A1 - Macrolides a base d'erythromycine - Google Patents

Macrolides a base d'erythromycine

Info

Publication number
TN2009000374A1
TN2009000374A1 TNP2009000374A TN2009000374A TN2009000374A1 TN 2009000374 A1 TN2009000374 A1 TN 2009000374A1 TN P2009000374 A TNP2009000374 A TN P2009000374A TN 2009000374 A TN2009000374 A TN 2009000374A TN 2009000374 A1 TN2009000374 A1 TN 2009000374A1
Authority
TN
Tunisia
Prior art keywords
macrolides
erythromycin
compounds
formula
relates
Prior art date
Application number
TNP2009000374A
Other languages
English (en)
Inventor
Sr Richard Allen Buzon
Mark Edward Flanagan
Zhengong Bryan Li
Thomas Victor Magee
Mark Carl Noe
Usa Datta Reilly
Daniel William Widlicka
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TN2009000374A1 publication Critical patent/TN2009000374A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention concerne des composés de formule (I) dans laquelle R1, R2 et X sont tels que définis dans le présent mémoire. L'invention concerne également des compositions pharmaceutiques et méthodes de traitement d'infections bactériennes utilisant les composés de formule (I).
TNP2009000374A 2007-03-13 2009-09-11 Macrolides a base d'erythromycine TN2009000374A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89447507P 2007-03-13 2007-03-13
US2337008P 2008-01-24 2008-01-24
PCT/IB2008/000715 WO2008110918A2 (fr) 2007-03-13 2008-03-04 Macrolides

Publications (1)

Publication Number Publication Date
TN2009000374A1 true TN2009000374A1 (fr) 2010-12-31

Family

ID=39760163

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2009000374A TN2009000374A1 (fr) 2007-03-13 2009-09-11 Macrolides a base d'erythromycine

Country Status (28)

Country Link
US (1) US20080293646A1 (fr)
EP (1) EP2125851B1 (fr)
JP (1) JP4468487B1 (fr)
KR (1) KR20090110381A (fr)
CN (1) CN101631795A (fr)
AP (1) AP2009004985A0 (fr)
AR (1) AR065724A1 (fr)
AT (1) ATE471943T1 (fr)
AU (1) AU2008224633A1 (fr)
BR (1) BRPI0809002A2 (fr)
CA (1) CA2680527A1 (fr)
CL (1) CL2008000695A1 (fr)
CR (1) CR10998A (fr)
CU (1) CU20090155A7 (fr)
DE (1) DE602008001611D1 (fr)
DO (1) DOP2009000214A (fr)
EA (1) EA200901059A1 (fr)
EC (1) ECSP099627A (fr)
IL (1) IL200613A0 (fr)
MA (1) MA31252B1 (fr)
MX (1) MX2009009074A (fr)
PA (1) PA8772401A1 (fr)
PE (1) PE20090106A1 (fr)
SV (1) SV2009003368A (fr)
TN (1) TN2009000374A1 (fr)
TW (1) TW200848061A (fr)
UY (1) UY30957A1 (fr)
WO (1) WO2008110918A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169142A (en) * 2012-03-06 2019-02-18 Pfizer Macrocyclic derivatives for the treatment of proliferative diseases
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
HK1242920A1 (zh) 2014-10-08 2018-07-06 哈佛大学的校长及成员们 14-元酮内酯及其制备和使用方法
HK1250371A1 (zh) 2015-03-25 2018-12-14 President And Fellows Of Harvard College 具有修饰的脱氧糖胺糖的大环内酯及其用途
CN105924451B (zh) * 2016-04-27 2017-12-15 国家海洋局第三海洋研究所 具有抗茶叶致病真菌活性的大环内酯化合物及制备与用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA011281B1 (ru) * 2004-12-21 2009-02-27 Пфайзер Продактс Инк. Макролиды

Also Published As

Publication number Publication date
MA31252B1 (fr) 2010-03-01
CR10998A (es) 2009-09-11
JP2010521448A (ja) 2010-06-24
DE602008001611D1 (en) 2010-08-05
BRPI0809002A2 (pt) 2014-11-11
CU20090155A7 (es) 2011-04-26
PA8772401A1 (es) 2008-11-19
CL2008000695A1 (es) 2008-09-22
AU2008224633A1 (en) 2008-09-18
MX2009009074A (es) 2009-09-28
IL200613A0 (en) 2010-05-17
WO2008110918A3 (fr) 2009-01-29
EP2125851B1 (fr) 2010-06-23
JP4468487B1 (ja) 2010-05-26
EA200901059A1 (ru) 2010-02-26
EP2125851A2 (fr) 2009-12-02
UY30957A1 (es) 2008-10-31
TW200848061A (en) 2008-12-16
US20080293646A1 (en) 2008-11-27
ATE471943T1 (de) 2010-07-15
CA2680527A1 (fr) 2008-09-18
DOP2009000214A (es) 2009-10-31
SV2009003368A (es) 2009-11-09
ECSP099627A (es) 2009-10-30
CN101631795A (zh) 2010-01-20
AP2009004985A0 (en) 2009-10-31
KR20090110381A (ko) 2009-10-21
WO2008110918A2 (fr) 2008-09-18
PE20090106A1 (es) 2009-02-08
AR065724A1 (es) 2009-06-24

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