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PA8855001A1 - Monocarbamas - Google Patents

Monocarbamas

Info

Publication number
PA8855001A1
PA8855001A1 PA20098855001A PA8855001A PA8855001A1 PA 8855001 A1 PA8855001 A1 PA 8855001A1 PA 20098855001 A PA20098855001 A PA 20098855001A PA 8855001 A PA8855001 A PA 8855001A PA 8855001 A1 PA8855001 A1 PA 8855001A1
Authority
PA
Panama
Prior art keywords
monocarbamas
compounds
formula
refers
memory
Prior art date
Application number
PA20098855001A
Other languages
English (en)
Inventor
Singh Lall Manjinder
Edward Flanagan Mark
Joseph Brickner Steven
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PA8855001A1 publication Critical patent/PA8855001A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCIÓN SE REFIERE A COMPUESTOS DE LA FÓRMULA (1): EN LA QUE R1, R2, R3, R4, R5, Y R6 SON COMO SE DEFINEN EN LA PRESENTE MEMORIA. LA INVENCIÓN TAMBIÉN SE REFIERE A COMPOSICIONES FARMACÉUTICAS Y A MÉTODOS PARA TRATAR INFECCIONES BACTERIANAS USANDO LOS COMPUESTOS DE LA FÓRMULA (1).
PA20098855001A 2008-12-19 2009-12-18 Monocarbamas PA8855001A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13915908P 2008-12-19 2008-12-19

Publications (1)

Publication Number Publication Date
PA8855001A1 true PA8855001A1 (es) 2010-07-27

Family

ID=41727494

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20098855001A PA8855001A1 (es) 2008-12-19 2009-12-18 Monocarbamas

Country Status (15)

Country Link
US (2) US8252782B2 (es)
EP (1) EP2379546A1 (es)
JP (1) JP2012512863A (es)
KR (1) KR20110086742A (es)
CN (1) CN102325769A (es)
AR (1) AR074801A1 (es)
AU (1) AU2009329169B2 (es)
CA (1) CA2744756C (es)
IL (1) IL213216A0 (es)
MX (1) MX2011006541A (es)
PA (1) PA8855001A1 (es)
SG (1) SG171781A1 (es)
TW (1) TW201026696A (es)
UY (1) UY32336A (es)
WO (1) WO2010070523A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2744756C (en) * 2008-12-19 2013-05-28 Pfizer Inc. Monocarbams and their use as antibacterial agent
CA2815821C (en) 2010-11-29 2015-07-07 Pfizer Inc. Monobactams useful for treating bacterial infections
UY34585A (es) 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
SI3353175T1 (sl) * 2015-09-23 2020-11-30 Novartis Ag Soli in trdne oblike monobaktam antibiotika
CN105481812B (zh) * 2015-11-30 2020-04-21 重庆天奕恒化科技有限公司 一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法
EP3558987A1 (en) 2016-12-21 2019-10-30 AiCuris GmbH & Co. KG COMBINATION THERAPY WITH AMIDINE SUBSTITUTED ß-LACTAM COMPOUNDS AND ß-LACTAMASE INHIBITORS FOR INFECTIONS WITH ANTIBIOTIC RESISTANT BACTERIAL STRAINS
US11414411B2 (en) 2017-08-02 2022-08-16 Novartis Ag Chemical process for manufacturing monobactam antibiotic and intermediates thereof
JP7244493B2 (ja) 2017-08-23 2023-03-22 ヘルムホルツ－ツェントルム フュア インフェクツィオンスフォルシュンク ゲーエムベーハー 新規なシストバクタミド誘導体
CN111328327A (zh) 2017-08-31 2020-06-23 北兴化学工业株式会社 1-(n,n-二取代的氨基甲酰基)4-(取代的磺酰基)三唑啉-5-酮衍生物、4-(n,n-二取代的氨基甲酰基)1-(取代的磺酰基)三唑啉-5-酮衍生物和包含这些衍生物作为有效成分的除草剂
WO2019144969A1 (zh) 2018-01-29 2019-08-01 南京明德新药研发股份有限公司 用于治疗细菌感染的单环β-内酰胺化合物
EP3901150B1 (en) 2018-12-18 2025-12-03 Shenzhen Optimum Biological Technology Co., Ltd Monocyclic beta-lactam compound for use in the treatment of pneumonia
WO2021121387A1 (zh) 2019-12-19 2021-06-24 南京明德新药研发有限公司 化合物在制药中的应用
GEAP202516632A (en) 2022-04-22 2025-02-25 Vertex Pharma Heteroaryl compounds for the treatment of pain

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587047A (en) * 1981-04-09 1986-05-06 E. R. Squibb & Sons, Inc. 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
NZ199981A (en) 1981-04-09 1985-08-16 Squibb & Sons Inc 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines
US5006650A (en) * 1987-02-11 1991-04-09 The Upjohn Company Novel N-1 substituted beta-lactams as antibiotics
EP0344197B1 (en) 1987-02-11 1991-08-14 The Upjohn Company Novel n-1 substituted beta-lactams as antibiotics
JPH02502455A (ja) * 1987-02-27 1990-08-09 ジ・アップジョン・カンパニー ピリドンカルボン酸または酸誘導体を含有する抗生物質β‐ラクタム
CA1317298C (en) * 1987-03-03 1993-05-04 Upjohn Company (The) Antibiotic sulfonylaminocarbonyl activated .beta.-lactams
US4762922A (en) * 1987-07-01 1988-08-09 Squibb Corporation 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US5015737A (en) * 1987-07-22 1991-05-14 The Upjohn Company Therapeutically useful beta-lactams
US4777252A (en) 1987-08-13 1988-10-11 E. R. Squibb & Sons, Inc. 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US4889930A (en) 1987-12-21 1989-12-26 E. R. Squibb & Sons, Inc. Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein
JPH01305081A (ja) 1988-04-04 1989-12-08 E R Squibb & Sons Inc ３―アシルアミノ―１―［［［（置換スルホニル）アミノ〕カルボニル〕アミノ〕―２―アゼチジノン類
EP0344707A3 (en) 1988-06-02 1990-04-18 E.R. Squibb & Sons, Inc. 2-Oxo-1-[[(substituted sulfonyl)-amino]carbonyl]-azetidine derivatives
US4959470A (en) 1988-08-17 1990-09-25 E. R. Squibb & Sons, Inc. 2-oxo-[[(substituted sulfonyl)-amino]carbonyl]-azetidines
WO1990003376A1 (en) 1988-09-27 1990-04-05 The Upjohn Company Dihydroxyaryl 4-substituted monocarbams as antibiotics
CA2210787A1 (en) 1997-07-17 1999-01-17 William R. Collier Self-contained work station
KR101320718B1 (ko) 2007-03-23 2013-10-21 바실리어 파마슈티카 아게 세균 감염 치료용 조합 약제
CA2744756C (en) * 2008-12-19 2013-05-28 Pfizer Inc. Monocarbams and their use as antibacterial agent

Also Published As

Publication number Publication date
US20100160281A1 (en) 2010-06-24
JP2012512863A (ja) 2012-06-07
US8324198B1 (en) 2012-12-04
MX2011006541A (es) 2011-07-20
CN102325769A (zh) 2012-01-18
EP2379546A1 (en) 2011-10-26
AU2009329169A1 (en) 2010-06-24
TW201026696A (en) 2010-07-16
CA2744756A1 (en) 2010-06-24
WO2010070523A1 (en) 2010-06-24
KR20110086742A (ko) 2011-07-29
US8252782B2 (en) 2012-08-28
AU2009329169B2 (en) 2012-06-28
CA2744756C (en) 2013-05-28
UY32336A (es) 2010-07-30
SG171781A1 (en) 2011-07-28
US20120289455A1 (en) 2012-11-15
AR074801A1 (es) 2011-02-16
IL213216A0 (en) 2011-07-31

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