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TN2009000109A1 - New benzamide derivatives as brad ykinin antagonists - Google Patents

New benzamide derivatives as brad ykinin antagonists

Info

Publication number
TN2009000109A1
TN2009000109A1 TN2009000109A TN2009000109A TN2009000109A1 TN 2009000109 A1 TN2009000109 A1 TN 2009000109A1 TN 2009000109 A TN2009000109 A TN 2009000109A TN 2009000109 A TN2009000109 A TN 2009000109A TN 2009000109 A1 TN2009000109 A1 TN 2009000109A1
Authority
TN
Tunisia
Prior art keywords
benzamide derivatives
new benzamide
brad ykinin
ykinin antagonists
new
Prior art date
Application number
TN2009000109A
Other languages
English (en)
Inventor
Istvan Vago
Gyula Beke
Eva Bozo
Sandor Farkas
Katalin Hornok
Gyorgy Keseru
Eva Schmidt
Eva Szentirmay
Monika Vastag
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of TN2009000109A1 publication Critical patent/TN2009000109A1/fr

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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TN2009000109A 2006-10-27 2009-03-30 New benzamide derivatives as brad ykinin antagonists TN2009000109A1 (en)

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HUP0600810A3 (en) * 2006-10-27 2008-09-29 Richter Gedeon Nyrt New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
HUP0600809A3 (en) * 2006-10-27 2008-09-29 Richter Gedeon Nyrt New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
EP2215055A1 (fr) * 2007-10-27 2010-08-11 Richter Gedeon Nyrt. Nouveaux dérivés non peptidiques utilisés comme antagonistes de la bradykinine du type b1
JP2012500801A (ja) * 2008-08-21 2012-01-12 リヒター ゲデオン ニルバーノシャン ミーケデーレスベニュタールシャシャーグ Ｃｎｓ疾患の治療法
CA2734651A1 (fr) * 2008-08-21 2010-02-25 Richter Gedeon Nyrt. Procede de traitement de douleur neuropathique
CA2759126C (fr) * 2009-02-26 2017-08-22 Boehringer Ingelheim International Gmbh Composes comme antagononistes de bradykinine b1
ES2350077B1 (es) * 2009-06-04 2011-11-04 Laboratorios Salvat, S.A. Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1.
US8912221B2 (en) * 2010-12-27 2014-12-16 Hoffmann-La Roche Inc. Biaryl amide derivatives
BR112016024473A2 (pt) * 2014-04-23 2018-01-23 X Rx Inc composto, composição farmacêutica, e, método para tratamento de uma doença e/ou condição
KR101676850B1 (ko) 2015-04-23 2016-11-18 한일화섬 주식회사 내구성이 우수한 스피커용 댐퍼 및 그 제조 방법
IL296716A (en) 2020-03-26 2022-11-01 Richter Gedeon Nyrt History of naphthyridine and pyrido[4,3-c]pyridazine as gabaa alpha 5 receptor modulators
HU231691B1 (hu) 2021-09-29 2025-10-28 Richter Gedeon Nyrt GABAA ALFA5 receptor modulátor hatású biciklusos aminszármazékok

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HUP0600809A3 (en) 2006-10-27 2008-09-29 Richter Gedeon Nyrt New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
HUP0600810A3 (en) 2006-10-27 2008-09-29 Richter Gedeon Nyrt New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
EP2215055A1 (fr) 2007-10-27 2010-08-11 Richter Gedeon Nyrt. Nouveaux dérivés non peptidiques utilisés comme antagonistes de la bradykinine du type b1
CA2717763A1 (fr) 2008-03-04 2009-09-11 John Bilello Diagnostic et surveillance de troubles depressifs bases sur une pluralite de panels de biomarqueurs
CA2734651A1 (fr) 2008-08-21 2010-02-25 Richter Gedeon Nyrt. Procede de traitement de douleur neuropathique
JP2012500801A (ja) 2008-08-21 2012-01-12 リヒター ゲデオン ニルバーノシャン ミーケデーレスベニュタールシャシャーグ Ｃｎｓ疾患の治療法
EP2529222A4 (fr) 2010-01-26 2013-10-09 Ridge Diagnostics Inc Panels de marqueurs biologiques multiples pour stratifier la sévérité d'une maladie et pour surveiller le traitement d'une dépression

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