TH83577A - Amino-Imidazolone For inhibition of B-zecretase - Google Patents
Amino-Imidazolone For inhibition of B-zecretaseInfo
- Publication number
- TH83577A TH83577A TH601000111A TH0601000111A TH83577A TH 83577 A TH83577 A TH 83577A TH 601000111 A TH601000111 A TH 601000111A TH 0601000111 A TH0601000111 A TH 0601000111A TH 83577 A TH83577 A TH 83577A
- Authority
- TH
- Thailand
- Prior art keywords
- amino
- formula
- beta
- zecretase
- imidazolone
- Prior art date
Links
- ZMLJHXQHPNGPJP-UHFFFAOYSA-N 4-aminoimidazol-2-one Chemical compound NC1=NC(=O)N=C1 ZMLJHXQHPNGPJP-UHFFFAOYSA-N 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 2
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 2
- 102100021257 Beta-secretase 1 Human genes 0.000 abstract 2
- 101000894895 Homo sapiens Beta-secretase 1 Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 210000001682 neurofibril Anatomy 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
Abstract
DC60 (29/03/49) การประดิษฐ์นี้จะจัดให้มีสารประกอบอะมิโน-อะมิดาโซโลน ที่มีสูตร I (สูตรเคมี) (I) ที่ถูกจัดให้มีอีกด้วย คือ สารผสม และวิธีการ สำหรับการใช้ของสิ่งเหล่านี้ เพื่อยับยั้ง เบตา-ซีครีเตส (BACE) และบำบัดรักษาการตกสะสมของ เบตา-อะไมลอยด์ และ การพันกันของนิวโรไฟบริล การประดิษฐ์นี้จะจัดให้มีสารประกอบอะมิโน-อะมิดาโซโลน ที่มีสูตร I (สูตรเคมี) (I) ที่ถูกจัดให้มีอีกด้วย คือ สารผสม และวิธีการ สำหรับการใช้ของสิ่งเหล่านี้ เพื่อยับยั้ง เบตา-ซีครีเตส (BACE) และบำบัดรักษาการตกสะสมของ เบตา-อะไมลอยด์ และ การพันกันของนิวโรไฟบริล สิทธิบัตรยา DC60 (29/03/49) This invention provides an amino-amidazolone compound with the formula I (chemical formula) (I) that is also provided, a mixture and a method for the Use of these to inhibit beta-sequestrate (BACE) and to treat Beta-amyloid and neurofibril tangles The invention will also provide amino-amidazolone compounds with formula I (chemical formula) (I) that are also provided, mixtures and methods for their use to inhibit beta. - Cecretase (BACE) and treatment of accumulation of Beta-amyloid and neurofibril tangles.Patent of drug.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH83577B TH83577B (en) | 2007-03-15 |
| TH83577A true TH83577A (en) | 2007-03-15 |
Family
ID=
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