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SV2004001373A - Inhibidores de pde9 para tratamiento de transtornos cardiovasculares. ref. pcs22051 - Google Patents

Inhibidores de pde9 para tratamiento de transtornos cardiovasculares. ref. pcs22051

Info

Publication number
SV2004001373A
SV2004001373A SV2002001373A SV2002001373A SV2004001373A SV 2004001373 A SV2004001373 A SV 2004001373A SV 2002001373 A SV2002001373 A SV 2002001373A SV 2002001373 A SV2002001373 A SV 2002001373A SV 2004001373 A SV2004001373 A SV 2004001373A
Authority
SV
El Salvador
Prior art keywords
rent
optionally replaced
treatment
pde9 inhibitors
cardiovascular disorders
Prior art date
Application number
SV2002001373A
Other languages
English (en)
Inventor
Michael Paul Deninno
Mark Ian Kemp
Michael John Palmer
Anthony Wood
Bernadette Hughes
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0126395A external-priority patent/GB0126395D0/en
Priority claimed from GB0130695A external-priority patent/GB0130695D0/en
Priority claimed from GB0216761A external-priority patent/GB0216761D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of SV2004001373A publication Critical patent/SV2004001373A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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Abstract

LA INVENCION SE REFIERE A LOS INHIBIDORES PDE9 PARA EL TRATAMIENTO DE TRASTORNOS CARDIOVASCULARES. LOS INHIBIDORES PDE9 PREERIDOS SON COMPUESTOS DE LA FORMULA I EN LOS QUE R1 ES H O ALQUILO C1-6, EN EL QUE R1 ESTA UNIDO BIEN A N1 O N2; R2 CES ALQUILO C1-6 OPCIONALMENTE SUSTITUIDO CON HIDROXI O ALCOXI; CICLOALQUILO C3-7 OPCIONALMENTE SUSTITUIDO CON ALQUILO, HIDROXI, O ALCOXI; UN HETEROCICLO SATURADO DE 5-6 MIEMBROS OPCIONALMENTE SUSTITUIDO CON ALQUILO, HIDROXI O ALCOXI; HET1 O AR1; R3 ES ALQUILO C1-6 OPCIONALMENTE SUSTITUIDO CON 1 O 2 GRUPOS INDEPENDIENTEMENTE SELECCIONADOS ENTRE: AR2; CICLOALQUILO C3-7 OPCIONALMENTE SUTITUIDO CON ALQUILO C1-6; O AR2; SAR2; NHC(O) ALQUILO C1-6; HET2; XANTENO Y NAFTALENO.
SV2002001373A 2001-11-02 2002-11-01 Inhibidores de pde9 para tratamiento de transtornos cardiovasculares. ref. pcs22051 SV2004001373A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0126395A GB0126395D0 (en) 2001-11-02 2001-11-02 Pyrazolo[4,3]pyrimidine derivatives and their use in treating disease
GB0130695A GB0130695D0 (en) 2001-12-21 2001-12-21 Pyrazola[4,3]pyrimidine
GB0216761A GB0216761D0 (en) 2002-07-18 2002-07-18 PDE9 Inhibitors for treating cardiovascular disorders

Publications (1)

Publication Number Publication Date
SV2004001373A true SV2004001373A (es) 2004-01-07

Family

ID=27256310

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2002001373A SV2004001373A (es) 2001-11-02 2002-11-01 Inhibidores de pde9 para tratamiento de transtornos cardiovasculares. ref. pcs22051

Country Status (14)

Country Link
EP (1) EP1440073A1 (es)
JP (1) JP2005511575A (es)
AR (1) AR037329A1 (es)
BR (1) BR0214096A (es)
CA (1) CA2466824A1 (es)
DO (1) DOP2002000482A (es)
HN (1) HN2002000317A (es)
MX (1) MXPA04004171A (es)
PA (1) PA8557401A1 (es)
PE (1) PE20030702A1 (es)
SV (1) SV2004001373A (es)
TW (1) TW200300081A (es)
UY (1) UY27522A1 (es)
WO (1) WO2003037899A1 (es)

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