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SV2004001367A - Compuestos y procedimientos antitumorales ref.x-15365 - Google Patents

Compuestos y procedimientos antitumorales ref.x-15365

Info

Publication number
SV2004001367A
SV2004001367A SV2002001367A SV2002001367A SV2004001367A SV 2004001367 A SV2004001367 A SV 2004001367A SV 2002001367 A SV2002001367 A SV 2002001367A SV 2002001367 A SV2002001367 A SV 2002001367A SV 2004001367 A SV2004001367 A SV 2004001367A
Authority
SV
El Salvador
Prior art keywords
procedures
ref
antitumor compounds
compounds
antitumor
Prior art date
Application number
SV2002001367A
Other languages
English (en)
Inventor
Dios Alfonso De
Cora Sue Grossman
Philip Arthur Hipskind
Ho-Shen Lin
Karen Lynn Lobb
Deuralde Gamendia Beatriz Lopez
Jose Eduardo Lopez
Mary Margaret Mader
Michael Enrico Richett
Chuan Shih
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SV2004001367A publication Critical patent/SV2004001367A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA COMPUESTOS ANTINEOPLASTICOS DE FORMULA; VER FORMULA, Y PROCEDIMIENTOS ANTINEOPLASTICOS
SV2002001367A 2001-10-25 2002-10-24 Compuestos y procedimientos antitumorales ref.x-15365 SV2004001367A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35201201P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
SV2004001367A true SV2004001367A (es) 2004-02-24

Family

ID=23383421

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2002001367A SV2004001367A (es) 2001-10-25 2002-10-24 Compuestos y procedimientos antitumorales ref.x-15365

Country Status (33)

Country Link
US (2) US7084170B2 (es)
EP (1) EP1442030B1 (es)
JP (1) JP4464681B2 (es)
KR (1) KR100913471B1 (es)
CN (1) CN1298709C (es)
AR (1) AR037248A1 (es)
AT (1) ATE338033T1 (es)
AU (1) AU2002334817B2 (es)
BR (1) BR0212386A (es)
CA (1) CA2463300C (es)
CY (1) CY1106247T1 (es)
DE (1) DE60214413T2 (es)
DK (1) DK1442030T3 (es)
EA (1) EA006081B1 (es)
EC (1) ECSP045078A (es)
EG (1) EG26021A (es)
ES (1) ES2269816T3 (es)
HR (1) HRP20040371B1 (es)
HU (1) HUP0401638A3 (es)
IL (2) IL160851A0 (es)
MX (1) MXPA04003886A (es)
MY (1) MY130718A (es)
NO (1) NO20041316L (es)
NZ (1) NZ531136A (es)
PE (1) PE20030574A1 (es)
PL (1) PL208083B1 (es)
PT (1) PT1442030E (es)
SI (1) SI1442030T1 (es)
SV (1) SV2004001367A (es)
TW (1) TWI281916B (es)
UA (1) UA75716C2 (es)
WO (1) WO2003035629A1 (es)
ZA (1) ZA200403089B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002100851A2 (en) * 2001-06-11 2002-12-19 Shire Biochem Inc. Thiophene derivatives as antiviral agents for flavivirus infection
SE0102616D0 (sv) * 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
US7375131B2 (en) * 2002-06-06 2008-05-20 Smithklinebeecham Corp. NF-κB inhibitors
US7402608B2 (en) 2002-12-10 2008-07-22 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of Flavivirus infections
SE0300091D0 (sv) * 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300092D0 (sv) * 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
US20050085531A1 (en) * 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
JP5134247B2 (ja) * 2004-09-13 2013-01-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド含有化合物の血管新生阻害物質との併用
US8772269B2 (en) 2004-09-13 2014-07-08 Eisai R&D Management Co., Ltd. Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
WO2006030941A1 (ja) * 2004-09-13 2006-03-23 Eisai R & D Management Co., Ltd. スルホンアミド含有化合物の血管新生阻害物質との併用
KR20070114774A (ko) * 2005-02-28 2007-12-04 에자이 알앤드디 매니지먼트 가부시키가이샤 술폰아미드 화합물의 혈관 신생 저해 물질과의 신규 병용
WO2006090930A1 (ja) 2005-02-28 2006-08-31 Eisai R & D Management Co., Ltd. スルホンアミド化合物の新規併用
WO2006090927A1 (ja) * 2005-02-28 2006-08-31 Eisai R & D Management Co., Ltd. スルホンアミド化合物の摂食亢進作用
SG161315A1 (en) * 2005-05-13 2010-05-27 Virochem Pharma Inc Compounds and methods for the treatment or prevention of flavivirus infections
US7208506B2 (en) * 2005-07-07 2007-04-24 Hoffmann-La Roche Inc. Heteroarylethenyl derivatives, their manufacture and use as pharmaceutical agents
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US20100291592A1 (en) 2006-04-20 2010-11-18 Taro Semba Novel marker for sensitivity against sulfonamide compound
US7939532B2 (en) 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
BRPI0718915A2 (pt) 2006-11-15 2013-12-03 Virochem Pharma Inc Análogos de tiofeno para o tratamento ou prevenção de infecções por flavivírus
JP2010526844A (ja) 2007-05-16 2010-08-05 エフ．ホフマン−ラ ロシュ アーゲー アリールピリジルスルホンアミド誘導体、それらの製造法及び医薬剤としての使用
CN101899008B (zh) * 2010-05-20 2012-10-17 中国人民解放军第二军医大学 N-取代嘧啶磺酰基-取代苯甲酰胺类化合物及其制备药物的用途
CN103450149B (zh) * 2012-06-01 2015-10-14 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物及其制备方法和用途
JP6364967B2 (ja) * 2014-05-30 2018-08-01 東ソー株式会社 ジチエノベンゾジチオフェンの製造方法
CN106588868A (zh) * 2016-11-16 2017-04-26 武汉理工大学 一种2‑溴‑3‑噻吩甲酸中间体的合成方法
CN108558822B (zh) * 2018-06-01 2020-12-18 盐城锦明药业有限公司 N-((5-溴噻吩-2-基)磺酰基)-2,4-二氯苯甲酰胺的合成方法
CN110835345A (zh) * 2018-08-17 2020-02-25 中国科学院上海药物研究所 一类细胞周期依赖性激酶的降解剂、其制备方法、药物组合物及其用途
CN109265437A (zh) * 2018-10-19 2019-01-25 凯莱英医药集团（天津）股份有限公司 一种3-羟基噻吩-2-羧酸酯类化合物的制备方法
WO2024251876A1 (en) * 2023-06-07 2024-12-12 KRæFTENS BEKæMPELSE PROTACs AND HyT-PD MOLECULES FOR TARGETED PROTEIN DEGRADATION OF DCAF15 AND THEIR USE IN THE TREATMENT OF AMYLOIDOSIS
WO2025031360A1 (zh) * 2023-08-09 2025-02-13 上海科技大学 磺酰胺类化合物及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA813332B (en) * 1980-06-21 1982-05-26 Pfizer Larvicides and isecticides
NZ238911A (en) * 1990-07-17 1993-10-26 Lilly Co Eli Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor
US5177074A (en) * 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
US6046228A (en) * 1996-07-05 2000-04-04 The United States Of America As Represented By The Department Of Health And Human Services Anti-viral pharmaceutical compositions containing saturated 1,2-dithiaheterocyclic compounds and uses thereof
EP0929540A4 (en) * 1996-10-04 2001-12-12 Lilly Co Eli ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS
JP4316787B2 (ja) 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、

Also Published As

Publication number Publication date
US20040198784A1 (en) 2004-10-07
CY1106247T1 (el) 2011-06-08
EP1442030A1 (en) 2004-08-04
DE60214413T2 (de) 2007-03-08
CN1575286A (zh) 2005-02-02
US7084170B2 (en) 2006-08-01
AU2002334817B2 (en) 2008-02-21
MXPA04003886A (es) 2004-07-08
AR037248A1 (es) 2004-11-03
HUP0401638A3 (en) 2012-09-28
IL160851A (en) 2009-11-18
JP2005511547A (ja) 2005-04-28
US7250430B2 (en) 2007-07-31
PT1442030E (pt) 2006-12-29
HRP20040371B1 (en) 2012-07-31
NO20041316L (no) 2004-03-30
DE60214413D1 (de) 2006-10-12
ZA200403089B (en) 2005-04-22
DK1442030T3 (da) 2006-12-27
EA006081B1 (ru) 2005-08-25
KR20040062583A (ko) 2004-07-07
HK1068337A1 (en) 2005-04-29
ES2269816T3 (es) 2007-04-01
US20060223871A1 (en) 2006-10-05
UA75716C2 (en) 2006-05-15
EG26021A (en) 2012-12-10
EP1442030B1 (en) 2006-08-30
PL208083B1 (pl) 2011-03-31
SI1442030T1 (sl) 2006-12-31
BR0212386A (pt) 2004-07-27
EA200400582A1 (ru) 2004-08-26
IL160851A0 (en) 2004-08-31
CA2463300A1 (en) 2003-05-01
JP4464681B2 (ja) 2010-05-19
CA2463300C (en) 2011-07-19
PL368234A1 (en) 2005-03-21
ATE338033T1 (de) 2006-09-15
NZ531136A (en) 2006-08-31
HUP0401638A2 (hu) 2004-11-29
TWI281916B (en) 2007-06-01
HRP20040371A2 (en) 2004-08-31
CN1298709C (zh) 2007-02-07
ECSP045078A (es) 2004-06-28
MY130718A (en) 2007-07-31
PE20030574A1 (es) 2003-07-03
KR100913471B1 (ko) 2009-08-25
WO2003035629A1 (en) 2003-05-01

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